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The map label for this gene is gluP [H]

Identifier: 117921137

GI number: 117921137

Start: 3221705

End: 3223063

Strand: Reverse

Name: gluP [H]

Synonym: Shewana3_2696

Alternate gene names: 117921137

Gene position: 3223063-3221705 (Counterclockwise)

Preceding gene: 117921138

Following gene: 117921128

Centisome position: 64.82

GC content: 50.18

Gene sequence:

>1359_bases
ATGAAATTCACGTCCGACAGTACCCAAGCCACGGCCTCGCCGCAGGGCAGTTTTATTCCTATGTTATTGATAGGGATTTT
ATTTTTTGTGTTTGGCTTTGTGACTTGGCTCAATGGTGCCTTGATCCCATTTTTAAAAATCGCCTGTCAGTTGAATGAGT
TTGAAGCCTATTTAGTCACCTTTGTGTTTTACATTGCTTATTTTGTGATGGCGCTGCCAACTTCATCCATCCTCACGCGT
CTTGGCTATAAGATGGGCATGACCTTAGGTTTAGGGATTATGGCGGCTGGCGCGGGCTTGTTTATTGTGGCGGCTTTGGT
CGGCCATTTTGCGACCTTCCTCTTGGCGTTATTTGTGTTGGGCACAGGCTTAACCTTGCTGCAAACGGCGGCCAATCCTT
ACATTGTCTGTATTGGCCCACGGGAAAGTGCGGCAATGCGGATAAGTTTAATGGGGATAGTGAATAAGGGCGCGGGCTTT
ATTGTGCCAATCATCTTCACGGCCTGGATTTTAACGGGCATGGAACCTTACAGTGAAACGGCATTGGCCAGCCTGTCCGA
GGCGCAGCGCCAATTGGCGTTAACGGAATTAGCCAATCGTTTAGTACACCCCTATTTAATGATGATGCTTGTACTTTTGG
GGTTGATGGCCTTTGTGTGGTTTTCACCGCTGCCAGAGCCCGAATTAGGAGAGCGAGTCGAGCGTACTCAAACCGATTGG
AAGGCTATTCTACAATATCCGCAGGTGATCTTAGGGGCACTGACACTCTTCTGTTATGTGGGCGCCGAGGTGATTGCTGG
TGATAGCATAGGACTATTCAGTCAGGGACTGGGGGTTGCGCACTTTGGCATGATGACCTCCTACACCATGGGATTTATGG
TACTGGGCTATGTGCTCGGAATCCTGCTGATCCCAAGATGGATCAGCCAGCAAACAGCATTAGTGGGCTCGGCTATCGCG
GGCTTGTTATTTACCCTCGGGGTCTTGCTCAGCGACAGTCAAAGCCAAGCTTTGTCTGAGCTGTTACTCGGTTGGTTAGG
CGTGTTACCCGTGCCCGATCCCGTGCTTTACTTAGCCCTACTTGGGTTAGCAAACGCCTTGGTATGGCCTGCGGTGTGGC
CATTAGCCCTTGAAGGGCTCGGGCGCTTAACAGCCACCGCATCGGCGTTACTGATCATGGGAATTGCGGGCGGTGCGATT
CTGCCACTGCTCTATGGCTACATCGCCCATAGTCAAGGTGACAGCCAAATGGCGTACTTCTTACTATTACCTTGTTACGG
CTTAATTTTTTACTACGCCATTTGGGGCCATAAGCTAACGGCCAAAGTGGCCTCAAGCATTGCGATGGTTAATGAATAG

Upstream 100 bases:

>100_bases
ACAATAACTAAAGCGGCATTTATTTGGGTGAGCTAAGTACTCAACCCATGGCCCATTCAACAAGCAAAATAACAATAAAC
TAATAACAAAAGGTGAAACG

Downstream 100 bases:

>100_bases
CAAAGAAAAGCCCCATGCTCAGCACTGTGGTTAATAGGGTATTACGCGTGACAAATGCTAATACCGTTGCGACCACAGCG
CATATCAAGTAGCTGTTATC

Product: major facilitator transporter

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKFTSDSTQATASPQGSFIPMLLIGILFFVFGFVTWLNGALIPFLKIACQLNEFEAYLVTFVFYIAYFVMALPTSSILTR
LGYKMGMTLGLGIMAAGAGLFIVAALVGHFATFLLALFVLGTGLTLLQTAANPYIVCIGPRESAAMRISLMGIVNKGAGF
IVPIIFTAWILTGMEPYSETALASLSEAQRQLALTELANRLVHPYLMMMLVLLGLMAFVWFSPLPEPELGERVERTQTDW
KAILQYPQVILGALTLFCYVGAEVIAGDSIGLFSQGLGVAHFGMMTSYTMGFMVLGYVLGILLIPRWISQQTALVGSAIA
GLLFTLGVLLSDSQSQALSELLLGWLGVLPVPDPVLYLALLGLANALVWPAVWPLALEGLGRLTATASALLIMGIAGGAI
LPLLYGYIAHSQGDSQMAYFLLLPCYGLIFYYAIWGHKLTAKVASSIAMVNE

Sequences:

>Translated_452_residues
MKFTSDSTQATASPQGSFIPMLLIGILFFVFGFVTWLNGALIPFLKIACQLNEFEAYLVTFVFYIAYFVMALPTSSILTR
LGYKMGMTLGLGIMAAGAGLFIVAALVGHFATFLLALFVLGTGLTLLQTAANPYIVCIGPRESAAMRISLMGIVNKGAGF
IVPIIFTAWILTGMEPYSETALASLSEAQRQLALTELANRLVHPYLMMMLVLLGLMAFVWFSPLPEPELGERVERTQTDW
KAILQYPQVILGALTLFCYVGAEVIAGDSIGLFSQGLGVAHFGMMTSYTMGFMVLGYVLGILLIPRWISQQTALVGSAIA
GLLFTLGVLLSDSQSQALSELLLGWLGVLPVPDPVLYLALLGLANALVWPAVWPLALEGLGRLTATASALLIMGIAGGAI
LPLLYGYIAHSQGDSQMAYFLLLPCYGLIFYYAIWGHKLTAKVASSIAMVNE
>Mature_452_residues
MKFTSDSTQATASPQGSFIPMLLIGILFFVFGFVTWLNGALIPFLKIACQLNEFEAYLVTFVFYIAYFVMALPTSSILTR
LGYKMGMTLGLGIMAAGAGLFIVAALVGHFATFLLALFVLGTGLTLLQTAANPYIVCIGPRESAAMRISLMGIVNKGAGF
IVPIIFTAWILTGMEPYSETALASLSEAQRQLALTELANRLVHPYLMMMLVLLGLMAFVWFSPLPEPELGERVERTQTDW
KAILQYPQVILGALTLFCYVGAEVIAGDSIGLFSQGLGVAHFGMMTSYTMGFMVLGYVLGILLIPRWISQQTALVGSAIA
GLLFTLGVLLSDSQSQALSELLLGWLGVLPVPDPVLYLALLGLANALVWPAVWPLALEGLGRLTATASALLIMGIAGGAI
LPLLYGYIAHSQGDSQMAYFLLLPCYGLIFYYAIWGHKLTAKVASSIAMVNE

Specific function: Intake of glucose and galactose (Potential) [H]

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=423, Percent_Identity=26.0047281323877, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005964
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48619; Mature: 48619

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTSDSTQATASPQGSFIPMLLIGILFFVFGFVTWLNGALIPFLKIACQLNEFEAYLVT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FVFYIAYFVMALPTSSILTRLGYKMGMTLGLGIMAAGAGLFIVAALVGHFATFLLALFVL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTGLTLLQTAANPYIVCIGPRESAAMRISLMGIVNKGAGFIVPIIFTAWILTGMEPYSET
HCCHHHHHHCCCCEEEEECCCCCHHHEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
ALASLSEAQRQLALTELANRLVHPYLMMMLVLLGLMAFVWFSPLPEPELGERVERTQTDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KAILQYPQVILGALTLFCYVGAEVIAGDSIGLFSQGLGVAHFGMMTSYTMGFMVLGYVLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ILLIPRWISQQTALVGSAIAGLLFTLGVLLSDSQSQALSELLLGWLGVLPVPDPVLYLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGLANALVWPAVWPLALEGLGRLTATASALLIMGIAGGAILPLLYGYIAHSQGDSQMAYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHH
LLLPCYGLIFYYAIWGHKLTAKVASSIAMVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFTSDSTQATASPQGSFIPMLLIGILFFVFGFVTWLNGALIPFLKIACQLNEFEAYLVT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
FVFYIAYFVMALPTSSILTRLGYKMGMTLGLGIMAAGAGLFIVAALVGHFATFLLALFVL
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTGLTLLQTAANPYIVCIGPRESAAMRISLMGIVNKGAGFIVPIIFTAWILTGMEPYSET
HCCHHHHHHCCCCEEEEECCCCCHHHEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHH
ALASLSEAQRQLALTELANRLVHPYLMMMLVLLGLMAFVWFSPLPEPELGERVERTQTDW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
KAILQYPQVILGALTLFCYVGAEVIAGDSIGLFSQGLGVAHFGMMTSYTMGFMVLGYVLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ILLIPRWISQQTALVGSAIAGLLFTLGVLLSDSQSQALSELLLGWLGVLPVPDPVLYLAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
LGLANALVWPAVWPLALEGLGRLTATASALLIMGIAGGAILPLLYGYIAHSQGDSQMAYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHH
LLLPCYGLIFYYAIWGHKLTAKVASSIAMVNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9168605 [H]