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The map label for this gene is ddc [H]

Identifier: 117921127

GI number: 117921127

Start: 3212207

End: 3213856

Strand: Direct

Name: ddc [H]

Synonym: Shewana3_2686

Alternate gene names: 117921127

Gene position: 3212207-3213856 (Clockwise)

Preceding gene: 117921126

Following gene: 117921129

Centisome position: 64.6

GC content: 51.27

Gene sequence:

>1650_bases
ATGACCCAAAAACTCCCTCGCCAAGCCATCGCATCCGAAGACAGTTTGATGCGAATTTTCACTGTGCCCGAAGATGCGGA
ATCCACCTTAAGCATCATCGAGCAGAAGCTTTCCGAGGACTTAGCCGGCTTTTTGGGTGACAGCATTGCCGCGCTGGAAA
AGCCGCTCTCCGAAATCGAAACCGATTTTCAAGCCTTTGAAATTCCAAGCCAGCCACGTTTTGTCTCCGACTATACCGAC
GAAATCATGCAAAATCTGGTGGCACATTCGGTGCATACGGCGGCGCCCAGTTTTATCGGCCATATGACCTCGGCGCTGCC
CTATTTCGTGTTACCACTGTCGAAGATGATGGTGGGGCTGAATCAAAACTTGGTCAAAATTGAAACCTCCAAAGCCTTTA
CGCCGCTTGAGCGTCAAGTGCTCGGCATGATGCACCATTTGATTTACGCTCAAGATGATGATTTTTATCGTAATTGGATG
CACAGTGCCAACCATTCCCTCGGCGCATTTTGCTCCGGCGGCACAGTGGCTAACATCACCGCCCTGTGGATTGCCCGCAA
CCAATTACTCAAGGCCGATGGCGACTTTAAAGGCGTGACCCGCGAAGGCTTAATCAAGGCGCTGCGCCACTATGGCTTCG
ATGATTTAGCAATTCTGGTCTCCGAGCGCGGCCACTACTCCTTAGGTAAGGCCGTCGATCTGCTCGGTATCGGTCGCGAC
AATATCATCAGCATCCCAACCGATGGCAATAACAAAGTCGACGTTGCCAAAATGCGCGAAGTTGCCGCCGAACTGGCGAA
TAAACGCATCAAAGTCATGGCGATTGTTGGGGTAGCAGGCACAACCGAGACGGGCAATATCGACCCACTGCGCGAACTTG
CCGCCTTAGCAAGTGAGTTAAACTGCCACTTCCATGTAGATGCGGCTTGGGGCGGCGCAAGCTTATTATCCAATAAATAC
CGTCACTTACTCGATGGTATTGAACTGGCAGACTCAGTCACCATCGATGCTCATAAGCAAATGTATGTCCCCATGGGCGC
GGGTATGGTGCTGTTTAAAAATCCTGAGTTTGCCCATGCCATTGCCCACCACGCCGAATATATCCTGCGCCGAGGCTCTA
AGGATTTAGGCAGCCAAACGCTCGAAGGCTCACGCCCCGGCATGGCCATGTTAGTGCATGCCTGTTTGCAGATTATTGGC
CGCGATGGTTACGAAATCCTGATCAACAACAGCCTTGAAAAAGCCCGTTATTTTGCCGAACAAATCGACGCACACCCTGA
CTTTGAGCTAGTCACCGCGCCAGAGCTGTGCCTGCTCACCTATCGTTATGTACCCGCGGAGGTGCAGGCCGCCATGCAAG
TGGCGATAGACCAAGGCGATAAGGTGAAACTCGCTCGCTTTAATGAGCTGCTCGATGGCCTAACCCAATTTATTCAAAAA
CATCAACGCGAACAGGGCAAATCCTTTGTCTCCCGTACCCGCATTCAACCCGCGCGCTACTTTAGACAACCCACAGTGGT
GTTTCGCGTCGTATTAGCTAATCCTTTGACTAGCCATGAGATCCTTAATCGAGTGCTTATCGAGCAAGGCGAAATTGCCG
CATTGGATAAAGAGTTCTTACCTGCACTATTAGCTATGGCCAATGAATAG

Upstream 100 bases:

>100_bases
CTTTTTGGTAATCCGTAAACGGGTTTAAGCGCCATGTATTTGGTTATACTCTTAATCACCTTTGCGGTTTCACTATAAGA
ATTAATAGACGGCAAGCCCC

Downstream 100 bases:

>100_bases
CGAGTGATTTAGTGCAAGCTTTAAATCTCACTCAAATACAGAGTGTTAATCACAAACAGCCGCAAATATTTGCGGCTGTT
TTTGTTTGCAAAGCTGGGAT

Product: pyridoxal-dependent decarboxylase

Products: NA

Alternate protein names: DABA decarboxylase; DABA-DC [H]

Number of amino acids: Translated: 549; Mature: 548

Protein sequence:

>549_residues
MTQKLPRQAIASEDSLMRIFTVPEDAESTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPSQPRFVSDYTD
EIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYAQDDDFYRNWM
HSANHSLGAFCSGGTVANITALWIARNQLLKADGDFKGVTREGLIKALRHYGFDDLAILVSERGHYSLGKAVDLLGIGRD
NIISIPTDGNNKVDVAKMREVAAELANKRIKVMAIVGVAGTTETGNIDPLRELAALASELNCHFHVDAAWGGASLLSNKY
RHLLDGIELADSVTIDAHKQMYVPMGAGMVLFKNPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIG
RDGYEILINNSLEKARYFAEQIDAHPDFELVTAPELCLLTYRYVPAEVQAAMQVAIDQGDKVKLARFNELLDGLTQFIQK
HQREQGKSFVSRTRIQPARYFRQPTVVFRVVLANPLTSHEILNRVLIEQGEIAALDKEFLPALLAMANE

Sequences:

>Translated_549_residues
MTQKLPRQAIASEDSLMRIFTVPEDAESTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPSQPRFVSDYTD
EIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYAQDDDFYRNWM
HSANHSLGAFCSGGTVANITALWIARNQLLKADGDFKGVTREGLIKALRHYGFDDLAILVSERGHYSLGKAVDLLGIGRD
NIISIPTDGNNKVDVAKMREVAAELANKRIKVMAIVGVAGTTETGNIDPLRELAALASELNCHFHVDAAWGGASLLSNKY
RHLLDGIELADSVTIDAHKQMYVPMGAGMVLFKNPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIG
RDGYEILINNSLEKARYFAEQIDAHPDFELVTAPELCLLTYRYVPAEVQAAMQVAIDQGDKVKLARFNELLDGLTQFIQK
HQREQGKSFVSRTRIQPARYFRQPTVVFRVVLANPLTSHEILNRVLIEQGEIAALDKEFLPALLAMANE
>Mature_548_residues
TQKLPRQAIASEDSLMRIFTVPEDAESTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIETDFQAFEIPSQPRFVSDYTDE
IMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGLNQNLVKIETSKAFTPLERQVLGMMHHLIYAQDDDFYRNWMH
SANHSLGAFCSGGTVANITALWIARNQLLKADGDFKGVTREGLIKALRHYGFDDLAILVSERGHYSLGKAVDLLGIGRDN
IISIPTDGNNKVDVAKMREVAAELANKRIKVMAIVGVAGTTETGNIDPLRELAALASELNCHFHVDAAWGGASLLSNKYR
HLLDGIELADSVTIDAHKQMYVPMGAGMVLFKNPEFAHAIAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGR
DGYEILINNSLEKARYFAEQIDAHPDFELVTAPELCLLTYRYVPAEVQAAMQVAIDQGDKVKLARFNELLDGLTQFIQKH
QREQGKSFVSRTRIQPARYFRQPTVVFRVVLANPLTSHEILNRVLIEQGEIAALDKEFLPALLAMANE

Specific function: Unknown

COG id: COG0076

COG function: function code E; Glutamate decarboxylase and related PLP-dependent proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the group II decarboxylase family [H]

Homologues:

Organism=Homo sapiens, GI197383062, Length=455, Percent_Identity=26.3736263736264, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI197276620, Length=477, Percent_Identity=25.7861635220126, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI4503875, Length=477, Percent_Identity=25.7861635220126, Blast_Score=142, Evalue=7e-34,
Organism=Homo sapiens, GI58331246, Length=390, Percent_Identity=27.9487179487179, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI194294551, Length=381, Percent_Identity=26.246719160105, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI4503281, Length=409, Percent_Identity=22.2493887530562, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI132814448, Length=409, Percent_Identity=22.2493887530562, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17555682, Length=471, Percent_Identity=25.4777070063694, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI71993062, Length=455, Percent_Identity=25.7142857142857, Blast_Score=144, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI71993058, Length=373, Percent_Identity=27.0777479892761, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17543922, Length=274, Percent_Identity=25.9124087591241, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI17136594, Length=446, Percent_Identity=27.5784753363229, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24657193, Length=395, Percent_Identity=25.0632911392405, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24657185, Length=395, Percent_Identity=25.0632911392405, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24657188, Length=395, Percent_Identity=25.0632911392405, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21356415, Length=388, Percent_Identity=22.9381443298969, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221476190, Length=243, Percent_Identity=24.2798353909465, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585143, Length=243, Percent_Identity=24.2798353909465, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24585139, Length=243, Percent_Identity=24.2798353909465, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002129
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR021115 [H]

Pfam domain/function: PF00282 Pyridoxal_deC [H]

EC number: =4.1.1.86 [H]

Molecular weight: Translated: 60830; Mature: 60698

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKLPRQAIASEDSLMRIFTVPEDAESTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIE
CCCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFQAFEIPSQPRFVSDYTDEIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQNLVKIETSKAFTPLERQVLGMMHHLIYAQDDDFYRNWMHSANHSLGAFCSGGTVANIT
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCCHHHHH
ALWIARNQLLKADGDFKGVTREGLIKALRHYGFDDLAILVSERGHYSLGKAVDLLGIGRD
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHEECCCC
NIISIPTDGNNKVDVAKMREVAAELANKRIKVMAIVGVAGTTETGNIDPLRELAALASEL
CEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
NCHFHVDAAWGGASLLSNKYRHLLDGIELADSVTIDAHKQMYVPMGAGMVLFKNPEFAHA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCEEEECCCHHHHH
IAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGRDGYEILINNSLEKARYFAE
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
QIDAHPDFELVTAPELCLLTYRYVPAEVQAAMQVAIDQGDKVKLARFNELLDGLTQFIQK
HHCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
HQREQGKSFVSRTRIQPARYFRQPTVVFRVVLANPLTSHEILNRVLIEQGEIAALDKEFL
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHH
PALLAMANE
HHHHHHCCC
>Mature Secondary Structure 
TQKLPRQAIASEDSLMRIFTVPEDAESTLSIIEQKLSEDLAGFLGDSIAALEKPLSEIE
CCCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TDFQAFEIPSQPRFVSDYTDEIMQNLVAHSVHTAAPSFIGHMTSALPYFVLPLSKMMVGL
CCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NQNLVKIETSKAFTPLERQVLGMMHHLIYAQDDDFYRNWMHSANHSLGAFCSGGTVANIT
CCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEECCCCHHHHH
ALWIARNQLLKADGDFKGVTREGLIKALRHYGFDDLAILVSERGHYSLGKAVDLLGIGRD
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHEECCCC
NIISIPTDGNNKVDVAKMREVAAELANKRIKVMAIVGVAGTTETGNIDPLRELAALASEL
CEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHC
NCHFHVDAAWGGASLLSNKYRHLLDGIELADSVTIDAHKQMYVPMGAGMVLFKNPEFAHA
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCEEEECCCHHHHH
IAHHAEYILRRGSKDLGSQTLEGSRPGMAMLVHACLQIIGRDGYEILINNSLEKARYFAE
HHHHHHHHHHCCCHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHH
QIDAHPDFELVTAPELCLLTYRYVPAEVQAAMQVAIDQGDKVKLARFNELLDGLTQFIQK
HHCCCCCCEEECCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
HQREQGKSFVSRTRIQPARYFRQPTVVFRVVLANPLTSHEILNRVLIEQGEIAALDKEFL
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHH
PALLAMANE
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9514614 [H]