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The map label for this gene is srpA [H]

Identifier: 117921124

GI number: 117921124

Start: 3208133

End: 3209131

Strand: Direct

Name: srpA [H]

Synonym: Shewana3_2683

Alternate gene names: 117921124

Gene position: 3208133-3209131 (Clockwise)

Preceding gene: 117921123

Following gene: 117921125

Centisome position: 64.52

GC content: 49.65

Gene sequence:

>999_bases
ATGCAGCCATATCATGCCAAACTCAGCTCACTCGCCACCGCTTGCCTAATGGTCGGCTCAGTGTTTGTCGCCCCACTTGC
CAGTGCGGCGGAGCGTACCATTCCCGAATTAGTGGATGCAGTGAACGGCACGCCAGATGCAGCGAGTCGCGAGGCGGGTA
AAAAAGTGAAACTGCGCAATCATACAAAAGGGTTTTGTACCTCGGGCTACTTTGCCCCCAATCCCCAATTACACGATTCA
CTCAACATTCCCTTTTTTAATCAAAATCCCATTAAAGTGACCGCCCGTTTTTCCCTCGGCGGCACCAATCCTAAGCTGTC
CGATAAGACTCCTGGGCGCTTTATGTCATTGAAAATTGATGGAGAGCGGGAAAACCTGAACTTTGTCACCACCAATGTGC
CAGTCTTCTTTGCCAGTAACCTTGAGGATTTTTATCTGTTCCAAACTAAAACCAAACAAGGCGCCGAAGGTAAGCAATGG
CTTATCGATAATAAGCCCGACGCCAAAGCCTTTTTCGACTATCTAAAACAATTGCCGCCGAGCCCGAGTTTTGCCAATAG
CCAGTACTTTGGGGTGAACAGTTTTCTGTTTACCGATAAGCAAAATAACAGCATTGCGGGTAAATGGATTTTTGAACCCG
TAGCGGACACGCAAGCACTCACTCCGCAAGCATTGGCACAGCTCGATGATGACTTTCTCAAGCCCGAGTTACTCAAGCGA
ATTCAGTCTCAACCCGCCAAGTGGGATCTGTATATTCAGTTAGCGGAACAAGGCGATGAGATTAATAACCCGACAGTGCT
CTGGCCCGAAGACCGCCAGCGCATTCTCGTCGGCCAAGTGGTGATTGATGGCAAGCGCGACAGCGATCCTCAAGTACAAC
AATGCGATAGAAGCATTTTTAACCCTCTGCTGCTCCCCAAAGGCATAGCAGCGTCGGATGACCCAATTCTCAATGCCCGC
ACCGCGGCATATGTGGAGTCCTTTATCCGTCGTCAATAA

Upstream 100 bases:

>100_bases
TCAGATATTCACACAATGAGTGAAAGATAATTTCGCCTCGTCCTTTCCTATAAATGCACAAGACACCCATACGGTTAAAT
TGCTTAAGGAAGGAAACCCC

Downstream 100 bases:

>100_bases
GCACGGCTCGCGGTGCGGTTCGCGTGAGCAAAACAATATTTTTAGCATTACATTCGAATTCACGGCCATTATTTTGTGCG
CACGCACAAAATAATGGCCA

Product: catalase domain-containing protein

Products: H2O; O2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MQPYHAKLSSLATACLMVGSVFVAPLASAAERTIPELVDAVNGTPDAASREAGKKVKLRNHTKGFCTSGYFAPNPQLHDS
LNIPFFNQNPIKVTARFSLGGTNPKLSDKTPGRFMSLKIDGERENLNFVTTNVPVFFASNLEDFYLFQTKTKQGAEGKQW
LIDNKPDAKAFFDYLKQLPPSPSFANSQYFGVNSFLFTDKQNNSIAGKWIFEPVADTQALTPQALAQLDDDFLKPELLKR
IQSQPAKWDLYIQLAEQGDEINNPTVLWPEDRQRILVGQVVIDGKRDSDPQVQQCDRSIFNPLLLPKGIAASDDPILNAR
TAAYVESFIRRQ

Sequences:

>Translated_332_residues
MQPYHAKLSSLATACLMVGSVFVAPLASAAERTIPELVDAVNGTPDAASREAGKKVKLRNHTKGFCTSGYFAPNPQLHDS
LNIPFFNQNPIKVTARFSLGGTNPKLSDKTPGRFMSLKIDGERENLNFVTTNVPVFFASNLEDFYLFQTKTKQGAEGKQW
LIDNKPDAKAFFDYLKQLPPSPSFANSQYFGVNSFLFTDKQNNSIAGKWIFEPVADTQALTPQALAQLDDDFLKPELLKR
IQSQPAKWDLYIQLAEQGDEINNPTVLWPEDRQRILVGQVVIDGKRDSDPQVQQCDRSIFNPLLLPKGIAASDDPILNAR
TAAYVESFIRRQ
>Mature_332_residues
MQPYHAKLSSLATACLMVGSVFVAPLASAAERTIPELVDAVNGTPDAASREAGKKVKLRNHTKGFCTSGYFAPNPQLHDS
LNIPFFNQNPIKVTARFSLGGTNPKLSDKTPGRFMSLKIDGERENLNFVTTNVPVFFASNLEDFYLFQTKTKQGAEGKQW
LIDNKPDAKAFFDYLKQLPPSPSFANSQYFGVNSFLFTDKQNNSIAGKWIFEPVADTQALTPQALAQLDDDFLKPELLKR
IQSQPAKWDLYIQLAEQGDEINNPTVLWPEDRQRILVGQVVIDGKRDSDPQVQQCDRSIFNPLLLPKGIAASDDPILNAR
TAAYVESFIRRQ

Specific function: Decomposes Hydrogen Peroxide Into Water And Oxygen; Serves To Protect Cells From The Toxic Effects Of Hydrogen Peroxide. [C]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI25147792, Length=299, Percent_Identity=26.7558528428094, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25151141, Length=299, Percent_Identity=26.7558528428094, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020835
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase [H]

EC number: 1.11.1.6 [C]

Molecular weight: Translated: 36984; Mature: 36984

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPYHAKLSSLATACLMVGSVFVAPLASAAERTIPELVDAVNGTPDAASREAGKKVKLRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEECC
HTKGFCTSGYFAPNPQLHDSLNIPFFNQNPIKVTARFSLGGTNPKLSDKTPGRFMSLKID
CCCCCEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEC
GERENLNFVTTNVPVFFASNLEDFYLFQTKTKQGAEGKQWLIDNKPDAKAFFDYLKQLPP
CCCCCCEEEEECCCEEEECCCCEEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCCC
SPSFANSQYFGVNSFLFTDKQNNSIAGKWIFEPVADTQALTPQALAQLDDDFLKPELLKR
CCCCCCCEEECCCEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHCHHCCCHHHHHH
IQSQPAKWDLYIQLAEQGDEINNPTVLWPEDRQRILVGQVVIDGKRDSDPQVQQCDRSIF
HHCCCCCEEEEEEEECCCCCCCCCEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHH
NPLLLPKGIAASDDPILNARTAAYVESFIRRQ
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MQPYHAKLSSLATACLMVGSVFVAPLASAAERTIPELVDAVNGTPDAASREAGKKVKLRN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEECC
HTKGFCTSGYFAPNPQLHDSLNIPFFNQNPIKVTARFSLGGTNPKLSDKTPGRFMSLKID
CCCCCEECCCCCCCCCCCCCCCCCEECCCCEEEEEEEEECCCCCCCCCCCCCCEEEEEEC
GERENLNFVTTNVPVFFASNLEDFYLFQTKTKQGAEGKQWLIDNKPDAKAFFDYLKQLPP
CCCCCCEEEEECCCEEEECCCCEEEEEEECCCCCCCCCEEEECCCCCHHHHHHHHHHCCC
SPSFANSQYFGVNSFLFTDKQNNSIAGKWIFEPVADTQALTPQALAQLDDDFLKPELLKR
CCCCCCCEEECCCEEEEECCCCCCCCEEEEECCCCCCCCCCHHHHHHHCHHCCCHHHHHH
IQSQPAKWDLYIQLAEQGDEINNPTVLWPEDRQRILVGQVVIDGKRDSDPQVQQCDRSIF
HHCCCCCEEEEEEEECCCCCCCCCEEECCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHH
NPLLLPKGIAASDDPILNARTAAYVESFIRRQ
CHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Heme Group. [C]

Metal ions: NA

Kcat value (1/min): 980000 [C]

Specific activity: NA

Km value (mM): 18.2 {H2O2}} 10 {H2O2}} 3.7 {H2O2}} [C]

Substrates: Hydrogen peroxide [C]

Specific reaction: (2) Hydrogen peroxide --> (2) H2O + O2 [C]

General reaction: Redox reaction [C]

Inhibitor: 3-Amino-1-H-1, 2, 4-triazolecoli, Rhodopseudomonascapsulata; Dianisidine; H2O2 [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7536734 [H]