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The map label for this gene is sapD [H]

Identifier: 117921094

GI number: 117921094

Start: 3166788

End: 3167795

Strand: Direct

Name: sapD [H]

Synonym: Shewana3_2653

Alternate gene names: 117921094

Gene position: 3166788-3167795 (Clockwise)

Preceding gene: 117921093

Following gene: 117921095

Centisome position: 63.69

GC content: 52.38

Gene sequence:

>1008_bases
ATGCCATTACTCGACGTTAGAAACCTGACCATTGAGCTCGACACGCCCCACGGCAGAGTGCGCGCCCTTGAGAAAGTGAG
TTTGACCCTGAACGCGGGGGAAATTCACGGTCTAGTGGGTGAATCGGGCTCGGGCCGCAGTCTGCTCGCCAGAGCTATTC
TTGGGATCCCAGGCCCCAATTGGACCATTACCGCCGACCGCATGATGTGGGATGGTAATAATCTGATGGCCATGACCTCG
AAGGAGCGCCGTAATCTGATGGGCTCAGATATGGCAATGATCTTCCAAGACCCCTCAGGCAGCCTTGACCCTTCGCAAAC
TGTGGGCAGTCAGCTGATGCAGGCCATGCCTAAGAACCCTAAGGCTTACTTTTGGCAAAAGCACAAACATGCCAAACTCA
CGGCACAAAAATGGCTGCATAAGGTCGGGATTAAGAATCCGCAAAAAGTGATGTTGAGTTATGCTTGGGAGCTTTCGGAA
GGCGAATGCCAAAAAGTGATGATCGCCATGGCAATTGCCAACCAACCGCGATTATTGATTGCCGACGAACCGACCAACTC
GATGGAGCTGAGCACTCAGGCGCAGATTTTCCGTCTGCTATCACAGCTTAACCAGCTACAAAACGTGTCGATTTTAATCA
TCAGCCACGAGCTTGAAACGCTGGCACAGTGGTGCGATCACCTATCCGTGCTCTATTGTGGCCAAGTCATGGAATCTGGC
CCAACGGAAGAACTGATCAATCAGCCGTATCATCCTTACACTAAGGCACTCTTGGATAATATGCCGGATTACTCGGGGAT
AGAGGCGCACAAAGCCATTATGCCAACCCTGCCAGGCTCGGCCCCCGCCCTGCAGCATCTGCCCATTGGTTGTCGCCTAG
GGCCAAGATGCCCTGAGGCACAAAAGAAATGCGTTAATCAGCCAAGTTTGAGTCATTTACGCGACCGCTACTTTGCCTGC
CATTTCCCTTACCACGGTGAAACGACAAATGACGACCCCACTGCTTAA

Upstream 100 bases:

>100_bases
TGTGACCATTCCAGGGCTGGCGATTCTTTTTAGTGTGCTCGCCATTAACTTGGTGGGCGATGGCTTGAGATCGGCGCTTG
CGCCCATCAGAAACTAACCT

Downstream 100 bases:

>100_bases
AGTTAACGATCTCTTTAAGAGGTACGATACCGGCTATAAGGGCTTTACCCGCCAATATAACGATGCCTTAGCCCCGGTTT
CCTTTGAATTAAACCGCGGC

Product: oligopeptide/dipeptide ABC transporter ATPase subunit

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MPLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPNWTITADRMMWDGNNLMAMTS
KERRNLMGSDMAMIFQDPSGSLDPSQTVGSQLMQAMPKNPKAYFWQKHKHAKLTAQKWLHKVGIKNPQKVMLSYAWELSE
GECQKVMIAMAIANQPRLLIADEPTNSMELSTQAQIFRLLSQLNQLQNVSILIISHELETLAQWCDHLSVLYCGQVMESG
PTEELINQPYHPYTKALLDNMPDYSGIEAHKAIMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNQPSLSHLRDRYFAC
HFPYHGETTNDDPTA

Sequences:

>Translated_335_residues
MPLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPNWTITADRMMWDGNNLMAMTS
KERRNLMGSDMAMIFQDPSGSLDPSQTVGSQLMQAMPKNPKAYFWQKHKHAKLTAQKWLHKVGIKNPQKVMLSYAWELSE
GECQKVMIAMAIANQPRLLIADEPTNSMELSTQAQIFRLLSQLNQLQNVSILIISHELETLAQWCDHLSVLYCGQVMESG
PTEELINQPYHPYTKALLDNMPDYSGIEAHKAIMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNQPSLSHLRDRYFAC
HFPYHGETTNDDPTA
>Mature_334_residues
PLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPNWTITADRMMWDGNNLMAMTSK
ERRNLMGSDMAMIFQDPSGSLDPSQTVGSQLMQAMPKNPKAYFWQKHKHAKLTAQKWLHKVGIKNPQKVMLSYAWELSEG
ECQKVMIAMAIANQPRLLIADEPTNSMELSTQAQIFRLLSQLNQLQNVSILIISHELETLAQWCDHLSVLYCGQVMESGP
TEELINQPYHPYTKALLDNMPDYSGIEAHKAIMPTLPGSAPALQHLPIGCRLGPRCPEAQKKCVNQPSLSHLRDRYFACH
FPYHGETTNDDPTA

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI21729873, Length=238, Percent_Identity=27.3109243697479, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI15149474, Length=238, Percent_Identity=27.3109243697479, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787548, Length=328, Percent_Identity=55.4878048780488, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1789963, Length=325, Percent_Identity=39.6923076923077, Blast_Score=247, Evalue=8e-67,
Organism=Escherichia coli, GI1787759, Length=325, Percent_Identity=36.3076923076923, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI48994883, Length=327, Percent_Identity=37.9204892966361, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI145693107, Length=336, Percent_Identity=31.547619047619, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787500, Length=313, Percent_Identity=33.2268370607029, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1788506, Length=262, Percent_Identity=35.1145038167939, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789962, Length=307, Percent_Identity=30.6188925081433, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1787758, Length=304, Percent_Identity=30.9210526315789, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789890, Length=267, Percent_Identity=31.8352059925094, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI48994997, Length=260, Percent_Identity=31.1538461538462, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789891, Length=219, Percent_Identity=31.9634703196347, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786398, Length=247, Percent_Identity=29.9595141700405, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787547, Length=261, Percent_Identity=29.5019157088123, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787792, Length=248, Percent_Identity=31.4516129032258, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081791, Length=268, Percent_Identity=26.1194029850746, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788225, Length=262, Percent_Identity=26.3358778625954, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87081834, Length=199, Percent_Identity=31.6582914572864, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789032, Length=257, Percent_Identity=26.8482490272374, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790162, Length=266, Percent_Identity=24.0601503759398, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788644, Length=254, Percent_Identity=27.9527559055118, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789586, Length=284, Percent_Identity=27.8169014084507, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787712, Length=265, Percent_Identity=25.6603773584906, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789873, Length=223, Percent_Identity=27.8026905829596, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1786345, Length=226, Percent_Identity=25.2212389380531, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1786319, Length=232, Percent_Identity=25.8620689655172, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787029, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=248, Percent_Identity=25.4032258064516, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790739, Length=246, Percent_Identity=25.2032520325203, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790544, Length=250, Percent_Identity=25.6, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787105, Length=248, Percent_Identity=25.4032258064516, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786563, Length=227, Percent_Identity=29.0748898678414, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786703, Length=219, Percent_Identity=29.2237442922374, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1786803, Length=239, Percent_Identity=23.8493723849372, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48995001, Length=237, Percent_Identity=27.8481012658228, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788761, Length=254, Percent_Identity=22.4409448818898, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790190, Length=229, Percent_Identity=24.8908296943231, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787089, Length=237, Percent_Identity=27.4261603375527, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081709, Length=260, Percent_Identity=21.1538461538462, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789991, Length=226, Percent_Identity=26.1061946902655, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=251, Percent_Identity=23.5059760956175, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788897, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786654, Length=244, Percent_Identity=25.4098360655738, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788450, Length=243, Percent_Identity=20.9876543209877, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1786253, Length=225, Percent_Identity=26.2222222222222, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=242, Percent_Identity=27.6859504132231, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI115534520, Length=232, Percent_Identity=25.4310344827586, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI193202349, Length=232, Percent_Identity=24.5689655172414, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37325; Mature: 37193

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPN
CCCCCCEEEEEEEECCCHHHHEEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGNNLMAMTSKERRNLMGSDMAMIFQDPSGSLDPSQTVGSQLMQAMPKNP
EEEEECCEEECCCCEEEECCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
KAYFWQKHKHAKLTAQKWLHKVGIKNPQKVMLSYAWELSEGECQKVMIAMAIANQPRLLI
CHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTNSMELSTQAQIFRLLSQLNQLQNVSILIISHELETLAQWCDHLSVLYCGQVMESG
EECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
PTEELINQPYHPYTKALLDNMPDYSGIEAHKAIMPTLPGSAPALQHLPIGCRLGPRCPEA
CHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHH
QKKCVNQPSLSHLRDRYFACHFPYHGETTNDDPTA
HHHHCCCCCHHHHHHHHEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
PLLDVRNLTIELDTPHGRVRALEKVSLTLNAGEIHGLVGESGSGRSLLARAILGIPGPN
CCCCCEEEEEEEECCCHHHHEEEEEEEEEECCCEEEECCCCCCCHHHHHHHHHCCCCCC
WTITADRMMWDGNNLMAMTSKERRNLMGSDMAMIFQDPSGSLDPSQTVGSQLMQAMPKNP
EEEEECCEEECCCCEEEECCHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCC
KAYFWQKHKHAKLTAQKWLHKVGIKNPQKVMLSYAWELSEGECQKVMIAMAIANQPRLLI
CHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEE
ADEPTNSMELSTQAQIFRLLSQLNQLQNVSILIISHELETLAQWCDHLSVLYCGQVMESG
EECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCC
PTEELINQPYHPYTKALLDNMPDYSGIEAHKAIMPTLPGSAPALQHLPIGCRLGPRCPEA
CHHHHHCCCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCHH
QKKCVNQPSLSHLRDRYFACHFPYHGETTNDDPTA
HHHHCCCCCHHHHHHHHEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]