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The map label for this gene is fabD [H]

Identifier: 117921000

GI number: 117921000

Start: 3061140

End: 3062066

Strand: Reverse

Name: fabD [H]

Synonym: Shewana3_2559

Alternate gene names: 117921000

Gene position: 3062066-3061140 (Counterclockwise)

Preceding gene: 117921001

Following gene: 117920999

Centisome position: 61.58

GC content: 49.08

Gene sequence:

>927_bases
ATGGAAAATGTAGCTTTTGTATTCCCAGGCCAAGGTTCACAGGCTCTAGGCATGTTAGCCGAGCTGGCTGGTGCACAGCC
GATTGTGGGACAAACCTTTGCCGAAGCGAGTGAGGTGTTAGGGTATGATCTGTGGGCATTAGTGCAAGACGGCCCCGCAG
AAACCTTAAATGAAACCGATAAAACCCAGCCTGCTTTATTAGCGGCAAGTGTGGCCATTTGGCGCGCTTACGTTGCTTCA
GGTAAAGCTATGCCTGCAATGTTAGCGGGTCACAGCCTAGGCGAATATTCTGCATTAGTTTGTGCTGGTGTCATCGACTT
TAAAGATGCGATCAAACTGGTTGAGCTACGTGGTCAACTGATGCAGCAAGCCGTGCCAGCGGGTACTGGCGCTATGTACG
CGATTATCGGTCTTGATAATGACGGTATTGCTAATGCGTGTATTGAAGCAGCCCAAGACGAAGTGGTGAGCCCAGTTAAC
TTCAACAGCCCAGGCCAAGTGGTTATCGCCGGTCAAAAAGAAGCGGTTGAACGTGCAGCTGCTGCCTGTAAAGCGGCGGG
CGCCAAAATGGCGGTTGCTCTGCCTGTCAGCGTGCCATCACACTGCGCATTAATGAAACCTGCTGCTGATAAATTAGCGG
TAGCTTTAAATGATGTGCAGTTTAATGCGCCAAGCATCACTGTTATCAATAACGTAGATGTGGCATCACCCACTGCGGTT
GCCGACATTAAAGATGCGCTGGTTCGTCAACTGTATTGCCCAGTACGCTGGAGCGAAACCGTTGAATTAATGGCCGAAAA
AGGTATTACACAGTTAGTTGAGTGTGGTCCTGGTAAAGTATTGACAGGTCTTGCGAAACGCATTAATAAATCTCTTTCTG
CCCAAGCAGTTAATGACGTTGCATCCCTTGCCGCGTTAACTGAATAA

Upstream 100 bases:

>100_bases
ATCTGTATACGACTAAATTCCTAACTATCGTTATCTTGGTTTGCTGTCCAAGATAACGGTTTAGTGTTCAATAAATTAAG
TTCGCCATAGGTAATTTGAT

Downstream 100 bases:

>100_bases
GGAGTTTGTATGAGTATCAATCTGAGTTTAGCGGGCAAAGTTGCCTTAGTGACAGGCGCGAGCCGTGGTATCGGCCGTGC
GATTGCTGAAACCTTAGTCG

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MENVAFVFPGQGSQALGMLAELAGAQPIVGQTFAEASEVLGYDLWALVQDGPAETLNETDKTQPALLAASVAIWRAYVAS
GKAMPAMLAGHSLGEYSALVCAGVIDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNDGIANACIEAAQDEVVSPVN
FNSPGQVVIAGQKEAVERAAAACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPSITVINNVDVASPTAV
ADIKDALVRQLYCPVRWSETVELMAEKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE

Sequences:

>Translated_308_residues
MENVAFVFPGQGSQALGMLAELAGAQPIVGQTFAEASEVLGYDLWALVQDGPAETLNETDKTQPALLAASVAIWRAYVAS
GKAMPAMLAGHSLGEYSALVCAGVIDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNDGIANACIEAAQDEVVSPVN
FNSPGQVVIAGQKEAVERAAAACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPSITVINNVDVASPTAV
ADIKDALVRQLYCPVRWSETVELMAEKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE
>Mature_308_residues
MENVAFVFPGQGSQALGMLAELAGAQPIVGQTFAEASEVLGYDLWALVQDGPAETLNETDKTQPALLAASVAIWRAYVAS
GKAMPAMLAGHSLGEYSALVCAGVIDFKDAIKLVELRGQLMQQAVPAGTGAMYAIIGLDNDGIANACIEAAQDEVVSPVN
FNSPGQVVIAGQKEAVERAAAACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPSITVINNVDVASPTAV
ADIKDALVRQLYCPVRWSETVELMAEKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDVASLAALTE

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=311, Percent_Identity=34.0836012861736, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI27477045, Length=110, Percent_Identity=41.8181818181818, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=68.1818181818182, Blast_Score=398, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71984332, Length=296, Percent_Identity=30.7432432432432, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=292, Percent_Identity=29.1095890410959, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24665753, Length=318, Percent_Identity=33.0188679245283, Blast_Score=139, Evalue=3e-33,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31770; Mature: 31770

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENVAFVFPGQGSQALGMLAELAGAQPIVGQTFAEASEVLGYDLWALVQDGPAETLNETD
CCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCC
KTQPALLAASVAIWRAYVASGKAMPAMLAGHSLGEYSALVCAGVIDFKDAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNDGIANACIEAAQDEVVSPVNFNSPGQVVIAGQKEAVERAA
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPSITVINNVDVASPTAV
HHHHHCCCCEEEEEECCCCCCHHCCCCCHHHHEEEEECEEECCCCEEEEECCCCCCCHHH
ADIKDALVRQLYCPVRWSETVELMAEKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLAALTE
HHHHHHCC
>Mature Secondary Structure
MENVAFVFPGQGSQALGMLAELAGAQPIVGQTFAEASEVLGYDLWALVQDGPAETLNETD
CCCEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHEECCCCHHHHCCCC
KTQPALLAASVAIWRAYVASGKAMPAMLAGHSLGEYSALVCAGVIDFKDAIKLVELRGQL
CCCHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MQQAVPAGTGAMYAIIGLDNDGIANACIEAAQDEVVSPVNFNSPGQVVIAGQKEAVERAA
HHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHHHHH
AACKAAGAKMAVALPVSVPSHCALMKPAADKLAVALNDVQFNAPSITVINNVDVASPTAV
HHHHHCCCCEEEEEECCCCCCHHCCCCCHHHHEEEEECEEECCCCEEEEECCCCCCCHHH
ADIKDALVRQLYCPVRWSETVELMAEKGITQLVECGPGKVLTGLAKRINKSLSAQAVNDV
HHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
ASLAALTE
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]