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The map label for this gene is fabF [H]

Identifier: 117920998

GI number: 117920998

Start: 3058542

End: 3059780

Strand: Reverse

Name: fabF [H]

Synonym: Shewana3_2557

Alternate gene names: 117920998

Gene position: 3059780-3058542 (Counterclockwise)

Preceding gene: 117920999

Following gene: 117920997

Centisome position: 61.54

GC content: 50.85

Gene sequence:

>1239_bases
GTGTCTAAACGTCGTGTAGTGGTAACCGGTTTAGGGTTAGTAACTCCCGTGGGTAATACTGTCGATACTACTTGGAAGGC
GCTGCTTTCGGGTAAGAGTGGTATTGCACCTATAACCAAATTTGATGCCAGCGAATTCACCACTCGTTTCAGTGGTTCTG
TAAAAGATTTTGATGTTGAGCAGTACTTAACCAAAAAAGACGCCCGTAAAATGGACCTCTTTATTCAATATGGTATGGCT
GCTGGCATCCAAGCTATCCAAGACTCGGGTCTGGATATGAGCAAAGAAAACCCAGGCCGCGTCGGTACCGCAATAGGTGC
GGGCATGGGCGGTATGTGGTTGATTGAACAAAACCACAGCGCGCTATTAAGCGGTGGCCCTCGTAAAATTTCGCCTTTCT
TCGTGCCAAGCACCATCATCAACATGATTGCTGGCCATTTATCGATTATGTACGGTATGACTGGGCCTAACTTTGCCGTC
ACGACCGCTTGTACTACCGGTGTGCACAACATTGGTTTTGCGGCGCGTACCATTGCCTATGGCGATGCTGATGTGATGAT
CGCAGGCGGCGCCGAAGATGTGACTTGTCCATTAGGCGTAGGTGGTTTTGGCGCGGCCAAAGCCCTATCAACCCGTAATG
ATGACCCAACGGCGGCCAGCCGTCCGTGGGACAAAGACCGTGATGGTTTCGTCATCGGTGATGGCGCGGGTGTGATGGTG
ATGGAAGAATACGAACATGCTAAGGCGCGCGGTGCGACCATTTATGGCGAACTTGTTGGCTTTGGTATGAGCGGTGATGC
GTTCCACATGACATCGCCTCCAAGCGATGGTGCGGGCGCTGCTGCGGCTATGGTTAATGCGGTGAATGATGCCAAGCTGT
CATTTGAAAAAATTGGTTATATCAATGCGCACGGTACTTCAACGCCAGCGGGCGATAAAGCCGAAGCGGCAGCGGTGAAA
TCTGTATTTGGCGACCACGCTTATAATCTGCTAGTTAGTTCGACTAAGTCTATGACGGGTCACTTGCTGGGCGCTGCGGG
TGCGGTTGAAGCGATTTTCACTTTGCTTGCGCTGCGCGATCAAGCCGTACCGCCGACCATCAACCTCGATAATCCAGACG
AAGGTTGTGATTTAGACTTCGTGGCACACACTGCCCGCGATGTGAAGTTAGAGTATGCTCTGTGTAACTCCTTCGGTTTT
GGTGGCACTAACGGTTCATTGCTGTTTAAGAAAGTCTAA

Upstream 100 bases:

>100_bases
TGTCCATGAGATGCTCGCCGCAGATTGGCGAAGATTCTTTATGATAGAAACACCATTATCTGTCATAACCTTATCTATTT
AGCATTAAAAGGTGACTGCC

Downstream 100 bases:

>100_bases
ACAGCGATTAGCCCGATAAAAAAATGCGCCTATGGGCGCATTTTTTTTATGCTCGAATTGTGCCGGATATCACTTTCTAA
CATGCTGATATCCTAAGGGT

Product: 3-oxoacyl-[acyl-carrier-protein] synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVEQYLTKKDARKMDLFIQYGMA
AGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHSALLSGGPRKISPFFVPSTIINMIAGHLSIMYGMTGPNFAV
TTACTTGVHNIGFAARTIAYGDADVMIAGGAEDVTCPLGVGGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAVNDAKLSFEKIGYINAHGTSTPAGDKAEAAAVK
SVFGDHAYNLLVSSTKSMTGHLLGAAGAVEAIFTLLALRDQAVPPTINLDNPDEGCDLDFVAHTARDVKLEYALCNSFGF
GGTNGSLLFKKV

Sequences:

>Translated_412_residues
MSKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVEQYLTKKDARKMDLFIQYGMA
AGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHSALLSGGPRKISPFFVPSTIINMIAGHLSIMYGMTGPNFAV
TTACTTGVHNIGFAARTIAYGDADVMIAGGAEDVTCPLGVGGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAVNDAKLSFEKIGYINAHGTSTPAGDKAEAAAVK
SVFGDHAYNLLVSSTKSMTGHLLGAAGAVEAIFTLLALRDQAVPPTINLDNPDEGCDLDFVAHTARDVKLEYALCNSFGF
GGTNGSLLFKKV
>Mature_411_residues
SKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVEQYLTKKDARKMDLFIQYGMAA
GIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHSALLSGGPRKISPFFVPSTIINMIAGHLSIMYGMTGPNFAVT
TACTTGVHNIGFAARTIAYGDADVMIAGGAEDVTCPLGVGGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMVM
EEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAVNDAKLSFEKIGYINAHGTSTPAGDKAEAAAVKS
VFGDHAYNLLVSSTKSMTGHLLGAAGAVEAIFTLLALRDQAVPPTINLDNPDEGCDLDFVAHTARDVKLEYALCNSFGFG
GTNGSLLFKKV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=414, Percent_Identity=47.3429951690821, Blast_Score=360, Evalue=1e-100,
Organism=Homo sapiens, GI223972627, Length=160, Percent_Identity=53.75, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI41872631, Length=404, Percent_Identity=25.990099009901, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=72.3970944309927, Blast_Score=605, Evalue=1e-174,
Organism=Escherichia coli, GI1788663, Length=416, Percent_Identity=39.1826923076923, Blast_Score=247, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=39.5631067961165, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI71983535, Length=264, Percent_Identity=45.4545454545455, Blast_Score=221, Evalue=5e-58,
Organism=Caenorhabditis elegans, GI212642053, Length=354, Percent_Identity=24.8587570621469, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17550940, Length=352, Percent_Identity=23.8636363636364, Blast_Score=92, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=40.8071748878924, Blast_Score=301, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24644341, Length=415, Percent_Identity=44.3373493975904, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI221330659, Length=381, Percent_Identity=24.6719160104987, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19920632, Length=381, Percent_Identity=24.6719160104987, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24581345, Length=379, Percent_Identity=23.4828496042216, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42901; Mature: 42770

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVE
CCCCEEEEEECEEECCCCCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHCCCCCCCCHH
QYLTKKDARKMDLFIQYGMAAGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHS
HHHHHHCCHHHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCCCEEEEECCCC
ALLSGGPRKISPFFVPSTIINMIAGHLSIMYGMTGPNFAVTTACTTGVHNIGFAARTIAY
EEECCCCCCCCCEECHHHHHHHHHHHHHEEECCCCCCEEEEEEHHCCCHHCCCCEEEEEE
GDADVMIAGGAEDVTCPLGVGGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
CCCCEEEECCCCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAVNDAKLSFEKIGY
EECHHHHHHCCCEEEEHHEECCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEHHHCEE
INAHGTSTPAGDKAEAAAVKSVFGDHAYNLLVSSTKSMTGHLLGAAGAVEAIFTLLALRD
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
QAVPPTINLDNPDEGCDLDFVAHTARDVKLEYALCNSFGFGGTNGSLLFKKV
CCCCCEECCCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SKRRVVVTGLGLVTPVGNTVDTTWKALLSGKSGIAPITKFDASEFTTRFSGSVKDFDVE
CCCEEEEEECEEECCCCCCHHHHHHHHHCCCCCCCCCEECCHHHHHHHHCCCCCCCCHH
QYLTKKDARKMDLFIQYGMAAGIQAIQDSGLDMSKENPGRVGTAIGAGMGGMWLIEQNHS
HHHHHHCCHHHHHHEEHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHCCCCCEEEEECCCC
ALLSGGPRKISPFFVPSTIINMIAGHLSIMYGMTGPNFAVTTACTTGVHNIGFAARTIAY
EEECCCCCCCCCEECHHHHHHHHHHHHHEEECCCCCCEEEEEEHHCCCHHCCCCEEEEEE
GDADVMIAGGAEDVTCPLGVGGFGAAKALSTRNDDPTAASRPWDKDRDGFVIGDGAGVMV
CCCCEEEECCCCCCEECCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCEEE
MEEYEHAKARGATIYGELVGFGMSGDAFHMTSPPSDGAGAAAAMVNAVNDAKLSFEKIGY
EECHHHHHHCCCEEEEHHEECCCCCCEEEECCCCCCCCCHHHHHHHHHCCCCEEHHHCEE
INAHGTSTPAGDKAEAAAVKSVFGDHAYNLLVSSTKSMTGHLLGAAGAVEAIFTLLALRD
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHC
QAVPPTINLDNPDEGCDLDFVAHTARDVKLEYALCNSFGFGGTNGSLLFKKV
CCCCCEECCCCCCCCCCCHHHHHCCCCEEEEEEEECCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]