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The map label for this gene is nagD [H]

Identifier: 117920988

GI number: 117920988

Start: 3044528

End: 3045274

Strand: Direct

Name: nagD [H]

Synonym: Shewana3_2547

Alternate gene names: 117920988

Gene position: 3044528-3045274 (Clockwise)

Preceding gene: 117920987

Following gene: 117920989

Centisome position: 61.23

GC content: 51.27

Gene sequence:

>747_bases
ATGAAAAATATTATCTGCGATATCGATGGTGTACTCCTGCACGACAATAAGCTGATCCCCGGCAGTGATAAATTTATCCA
CCGCGTTCTCGACCAAGGCAATCCCCTCGTTATTCTGACCAATTACCCAGTACAAACGGGTAAAGATCTGCAAAACCGCC
TCAGCGCCGCCGGGATAGACGTACCTGAAGAATGTTTTTACACCTCGGCCATGGCCACCGCCGATTTTTTAAAGCATCAA
GAAGGCAGTAAAGCCTTTGTGATTGGCGAAGGCGCCCTCACCCATGAGCTCTACAAGGCTGGCTTTACCATTACCGACAT
TAATCCCGACTTCGTGATTGTGGGTGAAACCCGCTCCTATAACTGGGATATGATCCATAAGGCCGCCGGATTCGTCGCCC
GCGGTGCCCGTTTTATCGCCACCAATCCCGACACTCACGGCCCCGCTTACAGTCCAGCATGCGGCGCCCTGTGTTCTCCA
ATAGAGCGCATTACTGGCAAAAAGCCCTTTTATGTGGGCAAGCCCAGCTCGTGGATTATTCGCTCGGCGCTCAACCATAT
CGACGGTCACTCCGAAAATACCGTGATCATTGGCGACAATATGCGTACCGATATTCTGGCGGGGTTTCAAGCGGGGCTTG
AGACCATTCTGGTTACCAGCGGCGTAAGTAAGCTTGAAGATATCGATAAAGAGCCTTTCCGCCCCAATCATGTATTCGCC
TGCGCCGGCGATATTGATGTAGTTTAA

Upstream 100 bases:

>100_bases
TTTTTTCGTCTTGTCATACAAAATCATTGTTTTCTCGCCTAATGTGGCATTAGATAAGCTAACGAAAAGTGATTTTGTTC
GGCATACAAGAGACTATTAG

Downstream 100 bases:

>100_bases
TCCTTAAATCGCCCGATTCTCAGCACCTTAGCGTGCTGAGAACCACAACAGACTCGATACGGTAAAGCAACATTAAGTAA
CATTTTTCCCCTTGGCTCTC

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKNIICDIDGVLLHDNKLIPGSDKFIHRVLDQGNPLVILTNYPVQTGKDLQNRLSAAGIDVPEECFYTSAMATADFLKHQ
EGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWDMIHKAAGFVARGARFIATNPDTHGPAYSPACGALCSP
IERITGKKPFYVGKPSSWIIRSALNHIDGHSENTVIIGDNMRTDILAGFQAGLETILVTSGVSKLEDIDKEPFRPNHVFA
CAGDIDVV

Sequences:

>Translated_248_residues
MKNIICDIDGVLLHDNKLIPGSDKFIHRVLDQGNPLVILTNYPVQTGKDLQNRLSAAGIDVPEECFYTSAMATADFLKHQ
EGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWDMIHKAAGFVARGARFIATNPDTHGPAYSPACGALCSP
IERITGKKPFYVGKPSSWIIRSALNHIDGHSENTVIIGDNMRTDILAGFQAGLETILVTSGVSKLEDIDKEPFRPNHVFA
CAGDIDVV
>Mature_248_residues
MKNIICDIDGVLLHDNKLIPGSDKFIHRVLDQGNPLVILTNYPVQTGKDLQNRLSAAGIDVPEECFYTSAMATADFLKHQ
EGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWDMIHKAAGFVARGARFIATNPDTHGPAYSPACGALCSP
IERITGKKPFYVGKPSSWIIRSALNHIDGHSENTVIIGDNMRTDILAGFQAGLETILVTSGVSKLEDIDKEPFRPNHVFA
CAGDIDVV

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=248, Percent_Identity=24.5967741935484, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI108796653, Length=261, Percent_Identity=26.8199233716475, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI14149777, Length=247, Percent_Identity=24.6963562753036, Blast_Score=74, Evalue=8e-14,
Organism=Escherichia coli, GI1786890, Length=248, Percent_Identity=72.1774193548387, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17562458, Length=286, Percent_Identity=25.5244755244755, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560956, Length=286, Percent_Identity=25.5244755244755, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558880, Length=265, Percent_Identity=26.0377358490566, Blast_Score=82, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6319965, Length=234, Percent_Identity=24.3589743589744, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666141, Length=254, Percent_Identity=28.3464566929134, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI22026920, Length=257, Percent_Identity=29.5719844357977, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24656326, Length=254, Percent_Identity=24.4094488188976, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656330, Length=251, Percent_Identity=25.8964143426295, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 26984; Mature: 26984

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIICDIDGVLLHDNKLIPGSDKFIHRVLDQGNPLVILTNYPVQTGKDLQNRLSAAGID
CCCEEEECCCEEEECCEECCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCC
VPEECFYTSAMATADFLKHQEGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSY
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCCCC
NWDMIHKAAGFVARGARFIATNPDTHGPAYSPACGALCSPIERITGKKPFYVGKPSSWII
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHH
RSALNHIDGHSENTVIIGDNMRTDILAGFQAGLETILVTSGVSKLEDIDKEPFRPNHVFA
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHEEECCCCHHHHHCCCCCCCCCEEEE
CAGDIDVV
ECCCCCCC
>Mature Secondary Structure
MKNIICDIDGVLLHDNKLIPGSDKFIHRVLDQGNPLVILTNYPVQTGKDLQNRLSAAGID
CCCEEEECCCEEEECCEECCCCHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHCCCC
VPEECFYTSAMATADFLKHQEGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSY
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCCCC
NWDMIHKAAGFVARGARFIATNPDTHGPAYSPACGALCSPIERITGKKPFYVGKPSSWII
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCHHHH
RSALNHIDGHSENTVIIGDNMRTDILAGFQAGLETILVTSGVSKLEDIDKEPFRPNHVFA
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHEEECCCCHHHHHCCCCCCCCCEEEE
CAGDIDVV
ECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]