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The map label for this gene is pepV [H]

Identifier: 117920934

GI number: 117920934

Start: 2980677

End: 2982278

Strand: Reverse

Name: pepV [H]

Synonym: Shewana3_2491

Alternate gene names: 117920934

Gene position: 2982278-2980677 (Counterclockwise)

Preceding gene: 117920936

Following gene: 117920933

Centisome position: 59.98

GC content: 50.62

Gene sequence:

>1602_bases
ATGGAATTGCCTCAGTTTAACTATACGAGCCTTTGTCGTCGTTTTTCTTATTCCCTATTAGCCGCTGCGCTGTGGACATC
GACGCAAGCTGCAGCGTCGCCAATCACGCTTAGCCAAGATGCGCTTAAGGTGGCCGATTATGCGGTGAGCACCTATGACG
TGCAGATGGTCGAGAGTCTGGCGCATTTAATCAGTTTTAATACCCAAGCGGTTGAGGGGCAGACACCCGATACCAACCCT
GCCTTTATTGGTTTTAAGTCGAGTTTAAAAAGCTTGAGCCAAGAACTCGGGCTCGATTATGCCGACCATGGTTATGTGGT
GCTGATTGGCCTCGATGCCAATGCTGTCGATGCCCAACGCTCACAGGTTGAGAAATTGGGCATCGTCACCCACGGCGATG
TGCAACCCGCCAATCCCGCACTCTGGGCCAAAAGCCCCTATGTGCTGGATACCGAGTCTGAACCTGGCAAGCTGATAGGT
CGCGGCACCGAAGATGATAAAGGCGCGATTGTCACCGCCATGTATGCGATGAAGGCCATCAAAGATAAACAACTCAAACG
GGAAAAACGCATTGAACTGTTGGTGTATTTAGCCGAAGAGTCCGATTGGGATCCGCTAAAGGCCTTTTTAGCCCATTACA
CCCCAGCGCAGATGAATATCACCATAGATGCTGAGTATCCTGTGGTTACCGCCGAAAAGGGTTGGAGTAAGATTGGCTTT
ACTGTACCGAATCTCGAGTTAACGCAGGAGCAGGGCGCGGCAACGAATATTCCGATCCTAATGGCATTTTCCGGCGGCTA
TTTTGCAAGCCAAGTACCACAGCAAGCCGAGGCGCAAATTCATGCGATCACCCCAAGCTTGTTTGAACAATTACAAACGA
GCGCCGTCAACCAGCAGGGGATGAAGTATCGATTCGAACGCACTTGCGAGCAGGCCGTGTGCGACTTGCATATTTTTGCC
GACGGTAAGGCGGCTCATTCCTCCACACCAGAAGATGGGGTGAATGCTGTGACGCATTTGGCCGCATTACTGCAGCCATA
CACTTGGCCAAAAACCACGGCGGCTTTAACCGTCGCCGCCATGAATGAGTTAGTGGGGTTGGGGATTTATGCCGAGCAGT
TTGGCGAGCTGGCCTATAAAGATGATTTTATGGGCGCGTTAACGCTGGCCCCCACTGTCGTTGCGCAAACGAGTAAAGGG
ACGGAAGTCACCATTAATTTACGTCGCCCTGTGGGCAAAACGCCTGAGTTACTCTCAGCCCAAGCCAAGGACGCACTGAA
CAAATGGCAAGCTGAGCATCAAGTGACACTCATCGACGTAGAAAGTTATTGGGGTGAACCTATGGTGATGAAAGATGCAC
CGCATCAGCAGACCTTACTCGATGTATTTGCCCACTTTACCGGCATAGCTTCACCCAAACCTGTGGCCATTGGCGGCTCA
ACCAACAGTAAATTATTTCCCAATGCCTTAAGTTTTGGCCCCGCCATGCCGGGTGTGGAATACACTGGTCACACGGAGAA
AGAATTTATTACCCATAAACAGTTTATGCTGAATCTGAAAATGTACACCGCCGCCTTTATTGAGTTAACCGCTGCAAAAT
AG

Upstream 100 bases:

>100_bases
TGAGCCGCGCACTAAGGCAATATTGGGCAAAGGATAAAGCCATTGCTTTGGTGCGTTTTAATGTAAGTCCCTAATCATAC
AAATAATAAATAGGACCTCT

Downstream 100 bases:

>100_bases
TGCGTTTTTTAATGTGATTAATTGAAGTTATGAGTGAAATACACAAGAAGGTGAAAGGCGCTGAGTTCACGCCAAGACTC
ATCGGTTTATAAGATAATGG

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MELPQFNYTSLCRRFSYSLLAAALWTSTQAAASPITLSQDALKVADYAVSTYDVQMVESLAHLISFNTQAVEGQTPDTNP
AFIGFKSSLKSLSQELGLDYADHGYVVLIGLDANAVDAQRSQVEKLGIVTHGDVQPANPALWAKSPYVLDTESEPGKLIG
RGTEDDKGAIVTAMYAMKAIKDKQLKREKRIELLVYLAEESDWDPLKAFLAHYTPAQMNITIDAEYPVVTAEKGWSKIGF
TVPNLELTQEQGAATNIPILMAFSGGYFASQVPQQAEAQIHAITPSLFEQLQTSAVNQQGMKYRFERTCEQAVCDLHIFA
DGKAAHSSTPEDGVNAVTHLAALLQPYTWPKTTAALTVAAMNELVGLGIYAEQFGELAYKDDFMGALTLAPTVVAQTSKG
TEVTINLRRPVGKTPELLSAQAKDALNKWQAEHQVTLIDVESYWGEPMVMKDAPHQQTLLDVFAHFTGIASPKPVAIGGS
TNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELTAAK

Sequences:

>Translated_533_residues
MELPQFNYTSLCRRFSYSLLAAALWTSTQAAASPITLSQDALKVADYAVSTYDVQMVESLAHLISFNTQAVEGQTPDTNP
AFIGFKSSLKSLSQELGLDYADHGYVVLIGLDANAVDAQRSQVEKLGIVTHGDVQPANPALWAKSPYVLDTESEPGKLIG
RGTEDDKGAIVTAMYAMKAIKDKQLKREKRIELLVYLAEESDWDPLKAFLAHYTPAQMNITIDAEYPVVTAEKGWSKIGF
TVPNLELTQEQGAATNIPILMAFSGGYFASQVPQQAEAQIHAITPSLFEQLQTSAVNQQGMKYRFERTCEQAVCDLHIFA
DGKAAHSSTPEDGVNAVTHLAALLQPYTWPKTTAALTVAAMNELVGLGIYAEQFGELAYKDDFMGALTLAPTVVAQTSKG
TEVTINLRRPVGKTPELLSAQAKDALNKWQAEHQVTLIDVESYWGEPMVMKDAPHQQTLLDVFAHFTGIASPKPVAIGGS
TNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELTAAK
>Mature_533_residues
MELPQFNYTSLCRRFSYSLLAAALWTSTQAAASPITLSQDALKVADYAVSTYDVQMVESLAHLISFNTQAVEGQTPDTNP
AFIGFKSSLKSLSQELGLDYADHGYVVLIGLDANAVDAQRSQVEKLGIVTHGDVQPANPALWAKSPYVLDTESEPGKLIG
RGTEDDKGAIVTAMYAMKAIKDKQLKREKRIELLVYLAEESDWDPLKAFLAHYTPAQMNITIDAEYPVVTAEKGWSKIGF
TVPNLELTQEQGAATNIPILMAFSGGYFASQVPQQAEAQIHAITPSLFEQLQTSAVNQQGMKYRFERTCEQAVCDLHIFA
DGKAAHSSTPEDGVNAVTHLAALLQPYTWPKTTAALTVAAMNELVGLGIYAEQFGELAYKDDFMGALTLAPTVVAQTSKG
TEVTINLRRPVGKTPELLSAQAKDALNKWQAEHQVTLIDVESYWGEPMVMKDAPHQQTLLDVFAHFTGIASPKPVAIGGS
TNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELTAAK

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 58137; Mature: 58137

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELPQFNYTSLCRRFSYSLLAAALWTSTQAAASPITLSQDALKVADYAVSTYDVQMVESL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
AHLISFNTQAVEGQTPDTNPAFIGFKSSLKSLSQELGLDYADHGYVVLIGLDANAVDAQR
HHHHHCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHH
SQVEKLGIVTHGDVQPANPALWAKSPYVLDTESEPGKLIGRGTEDDKGAIVTAMYAMKAI
HHHHHHCCEEECCCCCCCCCEECCCCEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHH
KDKQLKREKRIELLVYLAEESDWDPLKAFLAHYTPAQMNITIDAEYPVVTAEKGWSKIGF
HHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCCE
TVPNLELTQEQGAATNIPILMAFSGGYFASQVPQQAEAQIHAITPSLFEQLQTSAVNQQG
ECCCCEEECCCCCCCCCCEEEEECCCCHHHHCCCHHCCEEEEECHHHHHHHHHHHHHHHH
MKYRFERTCEQAVCDLHIFADGKAAHSSTPEDGVNAVTHLAALLQPYTWPKTTAALTVAA
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MNELVGLGIYAEQFGELAYKDDFMGALTLAPTVVAQTSKGTEVTINLRRPVGKTPELLSA
HHHHHHCCHHHHHHCCHHHCCCCCHHHHHCCHHEEECCCCCEEEEEECCCCCCCHHHHHH
QAKDALNKWQAEHQVTLIDVESYWGEPMVMKDAPHQQTLLDVFAHFTGIASPKPVAIGGS
HHHHHHHHHCCCCEEEEEEEHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCC
TNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELTAAK
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEECC
>Mature Secondary Structure
MELPQFNYTSLCRRFSYSLLAAALWTSTQAAASPITLSQDALKVADYAVSTYDVQMVESL
CCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHH
AHLISFNTQAVEGQTPDTNPAFIGFKSSLKSLSQELGLDYADHGYVVLIGLDANAVDAQR
HHHHHCCCCEECCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHH
SQVEKLGIVTHGDVQPANPALWAKSPYVLDTESEPGKLIGRGTEDDKGAIVTAMYAMKAI
HHHHHHCCEEECCCCCCCCCEECCCCEEEECCCCCCCEEECCCCCCCCHHHHHHHHHHHH
KDKQLKREKRIELLVYLAEESDWDPLKAFLAHYTPAQMNITIDAEYPVVTAEKGWSKIGF
HHHHHHHHCCEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCCE
TVPNLELTQEQGAATNIPILMAFSGGYFASQVPQQAEAQIHAITPSLFEQLQTSAVNQQG
ECCCCEEECCCCCCCCCCEEEEECCCCHHHHCCCHHCCEEEEECHHHHHHHHHHHHHHHH
MKYRFERTCEQAVCDLHIFADGKAAHSSTPEDGVNAVTHLAALLQPYTWPKTTAALTVAA
HHHHHHHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MNELVGLGIYAEQFGELAYKDDFMGALTLAPTVVAQTSKGTEVTINLRRPVGKTPELLSA
HHHHHHCCHHHHHHCCHHHCCCCCHHHHHCCHHEEECCCCCEEEEEECCCCCCCHHHHHH
QAKDALNKWQAEHQVTLIDVESYWGEPMVMKDAPHQQTLLDVFAHFTGIASPKPVAIGGS
HHHHHHHHHCCCCEEEEEEEHHHCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCEEECCC
TNSKLFPNALSFGPAMPGVEYTGHTEKEFITHKQFMLNLKMYTAAFIELTAAK
CCCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]