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The map label for this gene is htpG [H]

Identifier: 117920886

GI number: 117920886

Start: 2929409

End: 2931322

Strand: Reverse

Name: htpG [H]

Synonym: Shewana3_2443

Alternate gene names: 117920886

Gene position: 2931322-2929409 (Counterclockwise)

Preceding gene: 117920887

Following gene: 117920885

Centisome position: 58.95

GC content: 50.37

Gene sequence:

>1914_bases
ATGTCACAACAAGAAACTCATGGTTTTCAAACTGAAGTCAAACAGCTGTTGCATTTGATGATCCATTCTTTGTATTCCAA
CAAAGAAATTTTCTTGCGTGAACTGGTCTCCAATGCTGCGGATGCGGCCGATAAGCTGCGTTACCTTGCGTTGACCAACG
ACGCGCTATACGAAGGTGACGGTGAGCTACGTGTGCGCATTAGCGCAGACAAAGAAAAAGGCACTGTAACCATCGAAGAC
AACGGCGTAGGTATGACCCGCGATGGTGTGATTGAGCATTTAGGCACGATCGCCAAATCGGGCACCGCTGAATTCTTTAA
AAACCTCTCTGGCGAAGCCTCAAAGGATTCGCAGCTGATCGGTCAATTCGGTGTGGGCTTTTATTCGGCCTTTATCGTGG
CGAAAAAAGTCACTGTACGCACCCGTGCGGCAGGCCATAAGGCTAATGAAGCCGTATTGTGGGAATCGGAAGGTGAGGGC
AGTTTCACAGTCGATACCATCACTAAGGCGAGCCGTGGTACCGAGATCACTCTGCACCTGCGTGATGAAGAGAAAGAGTT
TGCCGATGAGTGGCGCCTACGCTCCATCATCACTAAATACTCAGACCATATCTCTGTACCAGTTGAAATGTGGCAGGAAG
GCACCCCTGAGCGCGATGGCCCAGACGGTGAAAAAATCCCCGCAACCGAAGGTTACTGGAAAGTCATGAACAAGGCGACT
GCGCTGTGGATGCGCAATAAGTCTGAGATCAGTGACGAAGAGTACCAAGAATTTTATAAGCACATTTCCCACGACTACAC
AGACGCACTGCTGTGGAGCCATAACCGCGTAGAAGGTAAACAGGAATACACTAACCTGTTGTATATCCCTTCAAAAGCAC
CATGGGATCTGTGGAACCGCGACCGTAAGCATGGTCTAAAACTCTTTGTTCAGCGCGTGTTTATCATGGATGACGCCGAG
CAGTTTATGCCATCTTACCTGCGCTTTGTGCAGGGTTTGATTGACTCAAACGATCTGCCGCTGAACGTGTCTCGCGAGAT
TTTACAGGACAACCACATCACCAAAGCGATGCGCACCGGTATCACTAAGCGCGTGCTGGGCATGTTGGAAAAACTGGCAA
AAGACGATGCGGAAAAATACCAACAATTCTGGGCCGAATTTGGTCAAGTGTTGAAGGAAGGTCCAGCGGAAGACTTTGCA
AACCGTGAGCGTATCGCAGGCTTATTGCGTTTTGCGTCTACCCATACGGGCAGCGCGGCACCGACTGTTTCACTCGATGA
CTACTTAAGCCGCATGAAGGAAGGCCAAAACAAGATTTACTATATCGTGGCCGACAGCCACGAAGCCGCGGCCAACAGCC
CACACTTAGAACTGCTGCGTAAGAAAGGCATCGAAGTGTTGCTGATGTCAGAACGTATCGACGAGTGGTTAATCAACCAC
TTAACTGAGTACAAAGAAAAACAATTGCACTCAGTCACCCGTGGCGAGCTGGAGTTAGGTGAGCTGGAAGATGCGGCCGA
GAAGGAAGCGCAAGAGAAACTCGCCGAAGAGTCTGCGCCATTGATTGAACGCATTAAAGCGGCATTAGGCGCTAGCGTGG
CCGATGTGAAAGTGACCTCACGCTTAACCGATACCCCAGCCTGTGTGGTGACGGGGGAAGGTGAGATGTCGAGCCAGATG
ATCAAACTGATGCAGGCTGCGGGTCAGCCAGTGCCAGAGGTCAAGCCGACGTTTGAGGTAAACCCTGCGCACCCATTAGT
ATCGCGCTTAAACGATCTTCAAGATGAAGCCGCCTTTGCCGATTGGTCGAATCTGTTATTGCAACAGGCGCAATTGTCGG
AGAAGGGCAGCCTAGCGGATCCATCGGCCTTTATTAAGCTGATGAACCAAATGTTATTGGCGAACCTGAAGTAA

Upstream 100 bases:

>100_bases
TGATTTTATCTCCCCCCTTGAAAAGTGGATTTACAGCCCCATTTTATTAATCACTAAGCGTTTGCTTTAACCAAATTGCG
TAACAAATAAGGAAAATTTC

Downstream 100 bases:

>100_bases
GACATTCGGGGCACTTGAGTCGAGACACAAGTGCCCCGATTCCGTTTTAGGCACCGCAAAGAGCATTATCCTAGGGCATT
TCTCTGTAGAGGTGCCAGTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 637; Mature: 636

Protein sequence:

>637_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIED
NGVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEG
SFTVDTITKASRGTEITLHLRDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKAT
ALWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFA
NRERIAGLLRFASTHTGSAAPTVSLDDYLSRMKEGQNKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLIERIKAALGASVADVKVTSRLTDTPACVVTGEGEMSSQM
IKLMQAAGQPVPEVKPTFEVNPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK

Sequences:

>Translated_637_residues
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIED
NGVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEG
SFTVDTITKASRGTEITLHLRDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKAT
ALWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNRDRKHGLKLFVQRVFIMDDAE
QFMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFA
NRERIAGLLRFASTHTGSAAPTVSLDDYLSRMKEGQNKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
LTEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLIERIKAALGASVADVKVTSRLTDTPACVVTGEGEMSSQM
IKLMQAAGQPVPEVKPTFEVNPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK
>Mature_636_residues
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGDGELRVRISADKEKGTVTIEDN
GVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLIGQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEGS
FTVDTITKASRGTEITLHLRDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKATA
LWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNRDRKHGLKLFVQRVFIMDDAEQ
FMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTGITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFAN
RERIAGLLRFASTHTGSAAPTVSLDDYLSRMKEGQNKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINHL
TEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLIERIKAALGASVADVKVTSRLTDTPACVVTGEGEMSSQMI
KLMQAAGQPVPEVKPTFEVNPAHPLVSRLNDLQDEAAFADWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI20149594, Length=681, Percent_Identity=38.0323054331865, Blast_Score=427, Evalue=1e-119,
Organism=Homo sapiens, GI4507677, Length=690, Percent_Identity=37.3913043478261, Blast_Score=422, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=644, Percent_Identity=34.3167701863354, Blast_Score=371, Evalue=1e-102,
Organism=Homo sapiens, GI154146191, Length=408, Percent_Identity=38.2352941176471, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI153792590, Length=408, Percent_Identity=38.2352941176471, Blast_Score=269, Evalue=8e-72,
Organism=Escherichia coli, GI1786679, Length=635, Percent_Identity=68.6614173228347, Blast_Score=891, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=38.4730538922156, Blast_Score=440, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17542208, Length=677, Percent_Identity=37.2230428360414, Blast_Score=415, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115535205, Length=647, Percent_Identity=31.3755795981453, Blast_Score=316, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI115535167, Length=452, Percent_Identity=34.7345132743363, Blast_Score=262, Evalue=3e-70,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=37.9411764705882, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=37.4269005847953, Blast_Score=439, Evalue=1e-124,
Organism=Drosophila melanogaster, GI17647529, Length=684, Percent_Identity=38.1578947368421, Blast_Score=462, Evalue=1e-130,
Organism=Drosophila melanogaster, GI21357739, Length=684, Percent_Identity=36.6959064327485, Blast_Score=411, Evalue=1e-115,
Organism=Drosophila melanogaster, GI24586016, Length=647, Percent_Identity=34.4667697063369, Blast_Score=363, Evalue=1e-100,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 71767; Mature: 71636

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGD
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECC
GELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHH
GQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEGSFTVDTITKASRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEHHHHHCCCCCEEEEEE
RDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNR
HHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCEEECCCCCCCCHHHH
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
ITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PTVSLDDYLSRMKEGQNKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LTEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLIERIKAALGASVADVKVTS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEHHH
RLTDTPACVVTGEGEMSSQMIKLMQAAGQPVPEVKPTFEVNPAHPLVSRLNDLQDEAAFA
HCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
DWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQQETHGFQTEVKQLLHLMIHSLYSNKEIFLRELVSNAADAADKLRYLALTNDALYEGD
CCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEEEECCCEEECC
GELRVRISADKEKGTVTIEDNGVGMTRDGVIEHLGTIAKSGTAEFFKNLSGEASKDSQLI
CCEEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHH
GQFGVGFYSAFIVAKKVTVRTRAAGHKANEAVLWESEGEGSFTVDTITKASRGTEITLHL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCEEEHHHHHCCCCCEEEEEE
RDEEKEFADEWRLRSIITKYSDHISVPVEMWQEGTPERDGPDGEKIPATEGYWKVMNKAT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALWMRNKSEISDEEYQEFYKHISHDYTDALLWSHNRVEGKQEYTNLLYIPSKAPWDLWNR
HHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHHCCEEECCCCCCCCHHHH
DRKHGLKLFVQRVFIMDDAEQFMPSYLRFVQGLIDSNDLPLNVSREILQDNHITKAMRTG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHHHHHHH
ITKRVLGMLEKLAKDDAEKYQQFWAEFGQVLKEGPAEDFANRERIAGLLRFASTHTGSAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCC
PTVSLDDYLSRMKEGQNKIYYIVADSHEAAANSPHLELLRKKGIEVLLMSERIDEWLINH
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHH
LTEYKEKQLHSVTRGELELGELEDAAEKEAQEKLAEESAPLIERIKAALGASVADVKVTS
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHEEHHH
RLTDTPACVVTGEGEMSSQMIKLMQAAGQPVPEVKPTFEVNPAHPLVSRLNDLQDEAAFA
HCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHHHHHHHHHHHH
DWSNLLLQQAQLSEKGSLADPSAFIKLMNQMLLANLK
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA