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The map label for this gene is bioH [C]

Identifier: 117920830

GI number: 117920830

Start: 2866785

End: 2867651

Strand: Reverse

Name: bioH [C]

Synonym: Shewana3_2387

Alternate gene names: 117920830

Gene position: 2867651-2866785 (Counterclockwise)

Preceding gene: 117920831

Following gene: 117920829

Centisome position: 57.67

GC content: 50.52

Gene sequence:

>867_bases
ATGTGGCAATCTTTCGCCCCCAAAAATCAAGTCGAGTTTGTGTTACCCCATATCAAGCTCAGTGGTCGATTATGGGGAGC
GAAAGATAAGCCGTTATTGCTCGCGTTGCATGGCTGGTTAGACAATGCGAACAGTTTTGAGCCTCTCGCTGAGTATTTGC
CTCATTATCAGATACTTGCCATAGATTGGCCCGGTCATGGCTTTTCTGCACATCGGCCGGGACATTATCCATTGCATTGG
ATTGACTATTTATACGATCTCGATGCGTTACTGGCGATGTTGCCGCAAAAGCCGCTGGCTATCATAGGGCATTCGTTAGG
GGGCATTATTGCCTCGGCGTATACCGCGACCTTTCCAGAAAAGGTCAACAAACTGATTTTGATTGAGGCGTTAAGCCCAC
TGTTTGAGTCGGCGACTCAAGCGAAAACGCGGCTGCGAAAGAGTTTTTATCAGCACGAGAAGTTTTTAGCGCAAAAGCAT
AAACAGCTAAAAGTCTACGACAACATGGACACCGCAGTAAAAGCCAGAGTGCACTTGACGGGGCTGGCGGAGCCTTGGTG
CCGCTTGTTACTCGAGCGCAATATGCAACCAACCACCGATGGTGTTGCGTGGCGTAGCGATCCAAGATTAAGGCTCGACT
CGCCCATGCGGCTGACCTTTGAGCAGGTTGATGCACTGATGCAGCATATTTCGGTCTCGACCTTATTGATCTGCGGCAAA
CAGGGTTTTAGCCAGCTGCAGGCGGCGCTGCCTAAGGCGAGGAAATGGTTCACACACTTGTCAGAACATATGCTCGAGGG
CGACCACCATGTGCACATGGATAACGCCAAAGGGGTCGCGCACTTGATCCAGCAGTTTGTCGAGTAA

Upstream 100 bases:

>100_bases
CGATACCGATAAGGAGAAATACCAAGCAATTGGTGAGAGCGATCGCATGACGCTCAAATTTATCAAAAAATCGCGCTAAT
CACCTGACATTAGAGGCAAT

Downstream 100 bases:

>100_bases
TCGCTTTTGCTTACATAAAAAAGACGCTAGGTTTTTTGTTTTTTTTATGTGATGATGATCAAAATTAAAACGCCCGTATG
ATTTATGCGGGTCAATCAAT

Product: alpha/beta hydrolase fold domain-containing protein

Products: NA

Alternate protein names: Hydrolase; Alpha/Beta Fold Family Hydrolase; Alpha/Beta Hydrolase; Hydrolase Alpha/Beta Fold Family; Alpha/Beta Hydrolase Fold Protein; Hydrolase/Acyltransferase; Lipase A; Lipase; Beta-Ketoacyl Synthase; Polyketide Synthase; Hydrolase Protein; Alpha/Beta Fold Superfamily Hydrolase; Hydrolase Or Acytransferase; Alpha/Beta Hydrolase Family Protein; Lipase LipA; Hydrolase Alpha/Beta Fold Family Protein; Epoxide Hydrolase; Alpha/Beta Superfamily Hydrolase; Alpha/Beta Fold Hydrolase Family Protein

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MWQSFAPKNQVEFVLPHIKLSGRLWGAKDKPLLLALHGWLDNANSFEPLAEYLPHYQILAIDWPGHGFSAHRPGHYPLHW
IDYLYDLDALLAMLPQKPLAIIGHSLGGIIASAYTATFPEKVNKLILIEALSPLFESATQAKTRLRKSFYQHEKFLAQKH
KQLKVYDNMDTAVKARVHLTGLAEPWCRLLLERNMQPTTDGVAWRSDPRLRLDSPMRLTFEQVDALMQHISVSTLLICGK
QGFSQLQAALPKARKWFTHLSEHMLEGDHHVHMDNAKGVAHLIQQFVE

Sequences:

>Translated_288_residues
MWQSFAPKNQVEFVLPHIKLSGRLWGAKDKPLLLALHGWLDNANSFEPLAEYLPHYQILAIDWPGHGFSAHRPGHYPLHW
IDYLYDLDALLAMLPQKPLAIIGHSLGGIIASAYTATFPEKVNKLILIEALSPLFESATQAKTRLRKSFYQHEKFLAQKH
KQLKVYDNMDTAVKARVHLTGLAEPWCRLLLERNMQPTTDGVAWRSDPRLRLDSPMRLTFEQVDALMQHISVSTLLICGK
QGFSQLQAALPKARKWFTHLSEHMLEGDHHVHMDNAKGVAHLIQQFVE
>Mature_288_residues
MWQSFAPKNQVEFVLPHIKLSGRLWGAKDKPLLLALHGWLDNANSFEPLAEYLPHYQILAIDWPGHGFSAHRPGHYPLHW
IDYLYDLDALLAMLPQKPLAIIGHSLGGIIASAYTATFPEKVNKLILIEALSPLFESATQAKTRLRKSFYQHEKFLAQKH
KQLKVYDNMDTAVKARVHLTGLAEPWCRLLLERNMQPTTDGVAWRSDPRLRLDSPMRLTFEQVDALMQHISVSTLLICGK
QGFSQLQAALPKARKWFTHLSEHMLEGDHHVHMDNAKGVAHLIQQFVE

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI18777795, Length=307, Percent_Identity=26.0586319218241, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17137390, Length=300, Percent_Identity=29.6666666666667, Blast_Score=108, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24655874, Length=305, Percent_Identity=29.8360655737705, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667992, Length=300, Percent_Identity=25, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI21357291, Length=306, Percent_Identity=24.8366013071895, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24667999, Length=296, Percent_Identity=25, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21356937, Length=291, Percent_Identity=25.4295532646048, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24655886, Length=144, Percent_Identity=31.9444444444444, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21356953, Length=145, Percent_Identity=31.0344827586207, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 32882; Mature: 32882

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWQSFAPKNQVEFVLPHIKLSGRLWGAKDKPLLLALHGWLDNANSFEPLAEYLPHYQILA
CCCCCCCCCCCEEEECCEEECCEEECCCCCCEEEEEECCCCCCCCCCHHHHHCCCEEEEE
IDWPGHGFSAHRPGHYPLHWIDYLYDLDALLAMLPQKPLAIIGHSLGGIIASAYTATFPE
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHH
KVNKLILIEALSPLFESATQAKTRLRKSFYQHEKFLAQKHKQLKVYDNMDTAVKARVHLT
HHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHEEEC
GLAEPWCRLLLERNMQPTTDGVAWRSDPRLRLDSPMRLTFEQVDALMQHISVSTLLICGK
CCHHHHHHHHHHCCCCCCCCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHEEECC
QGFSQLQAALPKARKWFTHLSEHMLEGDHHVHMDNAKGVAHLIQQFVE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHC
>Mature Secondary Structure
MWQSFAPKNQVEFVLPHIKLSGRLWGAKDKPLLLALHGWLDNANSFEPLAEYLPHYQILA
CCCCCCCCCCCEEEECCEEECCEEECCCCCCEEEEEECCCCCCCCCCHHHHHCCCEEEEE
IDWPGHGFSAHRPGHYPLHWIDYLYDLDALLAMLPQKPLAIIGHSLGGIIASAYTATFPE
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHH
KVNKLILIEALSPLFESATQAKTRLRKSFYQHEKFLAQKHKQLKVYDNMDTAVKARVHLT
HHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHEEEC
GLAEPWCRLLLERNMQPTTDGVAWRSDPRLRLDSPMRLTFEQVDALMQHISVSTLLICGK
CCHHHHHHHHHHCCCCCCCCCCEECCCCCEECCCCHHHHHHHHHHHHHHHHHHHHEEECC
QGFSQLQAALPKARKWFTHLSEHMLEGDHHVHMDNAKGVAHLIQQFVE
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA