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The map label for this gene is 117920782

Identifier: 117920782

GI number: 117920782

Start: 2812988

End: 2814445

Strand: Direct

Name: 117920782

Synonym: Shewana3_2339

Alternate gene names: NA

Gene position: 2812988-2814445 (Clockwise)

Preceding gene: 117920781

Following gene: 117920785

Centisome position: 56.57

GC content: 48.83

Gene sequence:

>1458_bases
ATGAATTTAACTGTGCCACTAACAGCCAAAGATGATGCCATAGAATGGGCGCTAACCCATGGGATGGCCTTTAAAGAAAC
TGCGTATTCCGCCCGCCACGCCCCATTTACCCTAACGCCCAGTTTAATCAGTAAAGCACACTATCAATATCTCAAAGGTG
CGGTGGAACCACTGGGTAAACTTATCCATTATGTGTCTGAAGCACATGCTTTTTTAGTTGATGCTATTCAACCTATTACA
GCAAGCGATCCCTTCTTTGCCGCGCTATTGAAAGCGCATCAACAGCTGCATGGCTCTGCACATAGCTCTACAAATAGCTC
TGGCACCCCAGCCCCAAGAATGCCACTGCTTATTATGCGTAGCGACTTTATGGACGATCGGGACTTAGGACCCAAACTGG
TGGAGTTTAATGGCATAGCGGCTGGCATGGGCCCCTTTGGGCAGCGGGCCCATCAACTTCATCGCTATTTACAGCAGCAA
TGGTCTATACAACCTAAGGGGGAACTGGTTGAAAATCATGCTATTGAACAATTATCCGTCGGCATAGCAACAGCAACCTT
TAAGATAAAACAGGAATTTGAAGATTCAGGACCGGCAAGATTTTTGATGCTAGTGCAAGAAAATGAAGACAATGTGTTTG
ATCAGCATTTGCTCGAACTCGCGCTGCAGCAAAAAGGAATACAAACCCTGCGCAGAACCTTGAGTGAACTGCAAGGGCAA
CTCACCACCGGCGCGCAGCAAAGGCTAATACTCGAAGGCGTGGGGACAATTGATACCGTCTATCTGCGTACAGGTTATCA
ATTTGCAGATTATGCAACCATCGACATCAATGGCAACAGGGATTACCAAGCCCTGATGGAGATCCGGGTGTTGCTTGAAC
AACATCGCATCGCCCTCAATGCGACCTTAGGCCAGCAGTTGGCAACCAGTAAACGAATGCAAATGCTGCTCTCGACTATG
GATGAACAGGCCTTAACTCAGTTTGGATTAACTCAGCCAGAAGCCAGCATGGTCAAGTCACTCCTCGGTGAAATGCGCCC
TGTCACCGCACAGAGCCCCCAGTTAATTGCCGAGTCCCCAATAGAGACTTGGGTCTTAAAAAATCAAGGGGAAGGCGGCG
GTCATTGTATTTTTGGCGCCGATATTCTCCCCAAATTAGCCGAGCTTGAGCCCGCACAATACCCAGTATGGTCCTTAATG
CGTCGCTTACACCCAAGGCCGAGAGCAACCCAGGCTTTAGTGGTACGCAACGGCGAAATACACATCATCGATGACTTGAT
CCCTGAAATTGGCATGTTCAGCGTCCACTGTGATGGCATAGCCGCCGTCAATGATAAAACCCATGCCGAGAGTCCCAGCT
ATGCGGGGTATTTAATTCGCAGCAAATCCGCCAAAGTCACAGAGGGCGGTGTTCACAGCGGCCAAGGGGTATTAGATTCG
CTGATGTTTAGTGATTGA

Upstream 100 bases:

>100_bases
GCACTCACTGTATGCCCTTAAAGTGAGTGCCTTAGGGCTACCCCCTACAAATGCAAAGACAGGTATTGCCAATAGACGCT
GTCAGTTTAAGAGAATCAAC

Downstream 100 bases:

>100_bases
TAGGGCGCGTATAAAGTAAAAAGCCACAGAATCTCATCTGTGGCTTTCACTAACAAATTAACCTCTATGATTAATAAGCG
GTTTTAACACCAAAACTGCG

Product: glutathione synthase

Products: ADP; phosphate; glutathione

Alternate protein names: Glutathione Synthetase

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MNLTVPLTAKDDAIEWALTHGMAFKETAYSARHAPFTLTPSLISKAHYQYLKGAVEPLGKLIHYVSEAHAFLVDAIQPIT
ASDPFFAALLKAHQQLHGSAHSSTNSSGTPAPRMPLLIMRSDFMDDRDLGPKLVEFNGIAAGMGPFGQRAHQLHRYLQQQ
WSIQPKGELVENHAIEQLSVGIATATFKIKQEFEDSGPARFLMLVQENEDNVFDQHLLELALQQKGIQTLRRTLSELQGQ
LTTGAQQRLILEGVGTIDTVYLRTGYQFADYATIDINGNRDYQALMEIRVLLEQHRIALNATLGQQLATSKRMQMLLSTM
DEQALTQFGLTQPEASMVKSLLGEMRPVTAQSPQLIAESPIETWVLKNQGEGGGHCIFGADILPKLAELEPAQYPVWSLM
RRLHPRPRATQALVVRNGEIHIIDDLIPEIGMFSVHCDGIAAVNDKTHAESPSYAGYLIRSKSAKVTEGGVHSGQGVLDS
LMFSD

Sequences:

>Translated_485_residues
MNLTVPLTAKDDAIEWALTHGMAFKETAYSARHAPFTLTPSLISKAHYQYLKGAVEPLGKLIHYVSEAHAFLVDAIQPIT
ASDPFFAALLKAHQQLHGSAHSSTNSSGTPAPRMPLLIMRSDFMDDRDLGPKLVEFNGIAAGMGPFGQRAHQLHRYLQQQ
WSIQPKGELVENHAIEQLSVGIATATFKIKQEFEDSGPARFLMLVQENEDNVFDQHLLELALQQKGIQTLRRTLSELQGQ
LTTGAQQRLILEGVGTIDTVYLRTGYQFADYATIDINGNRDYQALMEIRVLLEQHRIALNATLGQQLATSKRMQMLLSTM
DEQALTQFGLTQPEASMVKSLLGEMRPVTAQSPQLIAESPIETWVLKNQGEGGGHCIFGADILPKLAELEPAQYPVWSLM
RRLHPRPRATQALVVRNGEIHIIDDLIPEIGMFSVHCDGIAAVNDKTHAESPSYAGYLIRSKSAKVTEGGVHSGQGVLDS
LMFSD
>Mature_485_residues
MNLTVPLTAKDDAIEWALTHGMAFKETAYSARHAPFTLTPSLISKAHYQYLKGAVEPLGKLIHYVSEAHAFLVDAIQPIT
ASDPFFAALLKAHQQLHGSAHSSTNSSGTPAPRMPLLIMRSDFMDDRDLGPKLVEFNGIAAGMGPFGQRAHQLHRYLQQQ
WSIQPKGELVENHAIEQLSVGIATATFKIKQEFEDSGPARFLMLVQENEDNVFDQHLLELALQQKGIQTLRRTLSELQGQ
LTTGAQQRLILEGVGTIDTVYLRTGYQFADYATIDINGNRDYQALMEIRVLLEQHRIALNATLGQQLATSKRMQMLLSTM
DEQALTQFGLTQPEASMVKSLLGEMRPVTAQSPQLIAESPIETWVLKNQGEGGGHCIFGADILPKLAELEPAQYPVWSLM
RRLHPRPRATQALVVRNGEIHIIDDLIPEIGMFSVHCDGIAAVNDKTHAESPSYAGYLIRSKSAKVTEGGVHSGQGVLDS
LMFSD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4504169, Length=486, Percent_Identity=28.3950617283951, Blast_Score=141, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17535239, Length=490, Percent_Identity=24.0816326530612, Blast_Score=89, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6324524, Length=497, Percent_Identity=26.3581488933602, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI281361051, Length=500, Percent_Identity=26.2, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24642900, Length=500, Percent_Identity=26.2, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281361044, Length=500, Percent_Identity=26.2, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281361034, Length=500, Percent_Identity=26.2, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI281361053, Length=364, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI281376915, Length=364, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI281361042, Length=364, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI281361040, Length=364, Percent_Identity=26.9230769230769, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 6.3.2.3

Molecular weight: Translated: 53533; Mature: 53533

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTVPLTAKDDAIEWALTHGMAFKETAYSARHAPFTLTPSLISKAHYQYLKGAVEPLGK
CCEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
LIHYVSEAHAFLVDAIQPITASDPFFAALLKAHQQLHGSAHSSTNSSGTPAPRMPLLIMR
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
SDFMDDRDLGPKLVEFNGIAAGMGPFGQRAHQLHRYLQQQWSIQPKGELVENHAIEQLSV
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GIATATFKIKQEFEDSGPARFLMLVQENEDNVFDQHLLELALQQKGIQTLRRTLSELQGQ
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTGAQQRLILEGVGTIDTVYLRTGYQFADYATIDINGNRDYQALMEIRVLLEQHRIALN
HCCCHHHHHHHHCCCCCEEEEEECCCEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHEE
ATLGQQLATSKRMQMLLSTMDEQALTQFGLTQPEASMVKSLLGEMRPVTAQSPQLIAESP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCC
IETWVLKNQGEGGGHCIFGADILPKLAELEPAQYPVWSLMRRLHPRPRATQALVVRNGEI
CCEEEEECCCCCCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCE
HIIDDLIPEIGMFSVHCDGIAAVNDKTHAESPSYAGYLIRSKSAKVTEGGVHSGQGVLDS
EEHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHH
LMFSD
HHCCC
>Mature Secondary Structure
MNLTVPLTAKDDAIEWALTHGMAFKETAYSARHAPFTLTPSLISKAHYQYLKGAVEPLGK
CCEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHH
LIHYVSEAHAFLVDAIQPITASDPFFAALLKAHQQLHGSAHSSTNSSGTPAPRMPLLIMR
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEE
SDFMDDRDLGPKLVEFNGIAAGMGPFGQRAHQLHRYLQQQWSIQPKGELVENHAIEQLSV
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
GIATATFKIKQEFEDSGPARFLMLVQENEDNVFDQHLLELALQQKGIQTLRRTLSELQGQ
HHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTGAQQRLILEGVGTIDTVYLRTGYQFADYATIDINGNRDYQALMEIRVLLEQHRIALN
HCCCHHHHHHHHCCCCCEEEEEECCCEEECEEEEEECCCCHHHHHHHHHHHHHHHHHHEE
ATLGQQLATSKRMQMLLSTMDEQALTQFGLTQPEASMVKSLLGEMRPVTAQSPQLIAESP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCC
IETWVLKNQGEGGGHCIFGADILPKLAELEPAQYPVWSLMRRLHPRPRATQALVVRNGEI
CCEEEEECCCCCCCEEEECHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCE
HIIDDLIPEIGMFSVHCDGIAAVNDKTHAESPSYAGYLIRSKSAKVTEGGVHSGQGVLDS
EEHHHHHHCCCEEEEECCCEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHH
LMFSD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; gamma-L-glutamyl-L-cysteine; glycine

Specific reaction: ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA