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The map label for this gene is lolC [H]

Identifier: 117920730

GI number: 117920730

Start: 2748891

End: 2750123

Strand: Reverse

Name: lolC [H]

Synonym: Shewana3_2287

Alternate gene names: 117920730

Gene position: 2750123-2748891 (Counterclockwise)

Preceding gene: 117920734

Following gene: 117920729

Centisome position: 55.31

GC content: 52.47

Gene sequence:

>1233_bases
ATGGATCTTCGATTTCCTCTCTACGTTGGTTACCGTTATTGGCGGGCCAGAAAAGCAAACGCCTTTGCTTCTTTTATTAC
CTTATTTGCCGTTTCGGGCATTTTTTTAGGGGTGGCGGCCTTAATCGTGGTCAGCTCGGTGATGAATGGCCTCGAAGGGC
AATTAAAGCAGCGCATTTTAGGCGCAGTACCTCAATTGACTGTGGTGACTGAGGCGCCCTTAAGTGATTGGACTATACCT
GCGGACAAACTCAAAGCCTTGCCGGGCGTGCAGGGCGTGACGCCGAGCGTGTCGACCCAAGCCATGGTGCAATCGGCGGC
GAATATCCGCGCCGTGCAAGTGTTTGGGGTGTTTCCTGAGCTTGCCGAAAAACTCTCAATGGTGGCGCAGCATACCTATT
CGGGCGCATTTAACGAGTTAACTAGCGGCCAATATAAAGTCATCTTAGGCAGCGAGCTTGCGCGCCAATTAAAGGTGAGC
CCAGGTGATACTGTGCGTCTGTTAAGCGGCGATGGCGTGGTATATTCGCCGCTCGGCCCAGTCCCTAGCCAACGCAAGTT
TTTAGTGTCCGCCGTGTTTGAGATGGGCTCACAGGTGGATGCGGGCGTCGCATACATTCATTACCAAGATGCCAAGCGCT
TAATGCGTCAACCGAGCGATGAAATCAATCAGTTACGGCTGTATCTGAGCGATCCTTTTATGGCCCCCGCACTGGCTAAG
GATGTAAAGCAGGTTCTTACCCAGCAGGGTATAGAGGCGACAACCAGTGACTGGCGCGACACCTATGGTCATCTGTTTAG
TGCCGTGAAGATGGAAAAAAACATGATGTCGCTGATGCTGAGCCTGATTGTAGCCGTGGCGGCGTTTAATATAGTGTCGG
CGCTGGTGATGATGGTGGTGGATAAAACCACCGACGTGGCGGTACTCAAAACCCAAGGCTTACGTACCTCGGCGGTGATG
GGCATTTTTGTGGTGCAAGGGTTATTGAATGCGGTATTAGGTTTAGTACTGGGGCTGGTGGTCGGTATTCTGCTCACCCT
TAATTTGAATGGCATTATGGCGACCCTAGGGATTTCCATTTTAGGCACTGGGCAAGTGCTGCCAGTTAAATTGGAGCTGG
GCCAATTGTCGATGATTATTGTCGGCACCTTAGTCGTGACCTTAGTGGCGACCCTTTACCCCGCATTGCGAGCGGCGCGG
GTGCAACCTGCCACGGCGCTGCGTTACGAATAG

Upstream 100 bases:

>100_bases
GAACAAGGCTTGCCTCTTTATTTATAGGACCTAAACCCCTATTATCGTGCCCATCTTTATGATTTAGCAAGTTCAGCACA
CAGGACGCAGCCCTCTTTCA

Downstream 100 bases:

>100_bases
CTGCGATGTAACAAATTACAACGTCGCTCCCATGATGAGAGACGTGTTTGGACATGGAGTTTATCCATGTCATTTAGAAT
CAATAGCGAGAATCTCAATG

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MDLRFPLYVGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTVVTEAPLSDWTIP
ADKLKALPGVQGVTPSVSTQAMVQSAANIRAVQVFGVFPELAEKLSMVAQHTYSGAFNELTSGQYKVILGSELARQLKVS
PGDTVRLLSGDGVVYSPLGPVPSQRKFLVSAVFEMGSQVDAGVAYIHYQDAKRLMRQPSDEINQLRLYLSDPFMAPALAK
DVKQVLTQQGIEATTSDWRDTYGHLFSAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVVDKTTDVAVLKTQGLRTSAVM
GIFVVQGLLNAVLGLVLGLVVGILLTLNLNGIMATLGISILGTGQVLPVKLELGQLSMIIVGTLVVTLVATLYPALRAAR
VQPATALRYE

Sequences:

>Translated_410_residues
MDLRFPLYVGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTVVTEAPLSDWTIP
ADKLKALPGVQGVTPSVSTQAMVQSAANIRAVQVFGVFPELAEKLSMVAQHTYSGAFNELTSGQYKVILGSELARQLKVS
PGDTVRLLSGDGVVYSPLGPVPSQRKFLVSAVFEMGSQVDAGVAYIHYQDAKRLMRQPSDEINQLRLYLSDPFMAPALAK
DVKQVLTQQGIEATTSDWRDTYGHLFSAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVVDKTTDVAVLKTQGLRTSAVM
GIFVVQGLLNAVLGLVLGLVVGILLTLNLNGIMATLGISILGTGQVLPVKLELGQLSMIIVGTLVVTLVATLYPALRAAR
VQPATALRYE
>Mature_410_residues
MDLRFPLYVGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRILGAVPQLTVVTEAPLSDWTIP
ADKLKALPGVQGVTPSVSTQAMVQSAANIRAVQVFGVFPELAEKLSMVAQHTYSGAFNELTSGQYKVILGSELARQLKVS
PGDTVRLLSGDGVVYSPLGPVPSQRKFLVSAVFEMGSQVDAGVAYIHYQDAKRLMRQPSDEINQLRLYLSDPFMAPALAK
DVKQVLTQQGIEATTSDWRDTYGHLFSAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVVDKTTDVAVLKTQGLRTSAVM
GIFVVQGLLNAVLGLVLGLVVGILLTLNLNGIMATLGISILGTGQVLPVKLELGQLSMIIVGTLVVTLVATLYPALRAAR
VQPATALRYE

Specific function: Part of an ATP-dependent transport system lolCDE responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprote

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=405, Percent_Identity=40.4938271604938, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=31.4903846153846, Blast_Score=192, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44030; Mature: 44030

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRFPLYVGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTVVTEAPLSDWTIPADKLKALPGVQGVTPSVSTQAMVQSAANIRAVQVFGVFPE
HCCCCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEHEECCCHH
LAEKLSMVAQHTYSGAFNELTSGQYKVILGSELARQLKVSPGDTVRLLSGDGVVYSPLGP
HHHHHHHHHHHHHCCHHHHHCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCEEECCCCC
VPSQRKFLVSAVFEMGSQVDAGVAYIHYQDAKRLMRQPSDEINQLRLYLSDPFMAPALAK
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
DVKQVLTQQGIEATTSDWRDTYGHLFSAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKTTDVAVLKTQGLRTSAVMGIFVVQGLLNAVLGLVLGLVVGILLTLNLNGIMATLGISI
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHE
LGTGQVLPVKLELGQLSMIIVGTLVVTLVATLYPALRAARVQPATALRYE
EECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MDLRFPLYVGYRYWRARKANAFASFITLFAVSGIFLGVAALIVVSSVMNGLEGQLKQRIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAVPQLTVVTEAPLSDWTIPADKLKALPGVQGVTPSVSTQAMVQSAANIRAVQVFGVFPE
HCCCCEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEHEECCCHH
LAEKLSMVAQHTYSGAFNELTSGQYKVILGSELARQLKVSPGDTVRLLSGDGVVYSPLGP
HHHHHHHHHHHHHCCHHHHHCCCCEEEEECHHHHHHHCCCCCCEEEEEECCCEEECCCCC
VPSQRKFLVSAVFEMGSQVDAGVAYIHYQDAKRLMRQPSDEINQLRLYLSDPFMAPALAK
CCCHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
DVKQVLTQQGIEATTSDWRDTYGHLFSAVKMEKNMMSLMLSLIVAVAAFNIVSALVMMVV
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKTTDVAVLKTQGLRTSAVMGIFVVQGLLNAVLGLVLGLVVGILLTLNLNGIMATLGISI
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHE
LGTGQVLPVKLELGQLSMIIVGTLVVTLVATLYPALRAARVQPATALRYE
EECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]