Click here to switch to the map view.

The map label for this gene is cheA [H]

Identifier: 117920661

GI number: 117920661

Start: 2664764

End: 2666878

Strand: Reverse

Name: cheA [H]

Synonym: Shewana3_2218

Alternate gene names: 117920661

Gene position: 2666878-2664764 (Counterclockwise)

Preceding gene: 117920662

Following gene: 117920660

Centisome position: 53.64

GC content: 48.98

Gene sequence:

>2115_bases
ATGTCCATTAATATGGCAGAGTTCCATCAGGTTTTTTTTGAAGAAAGCCACGAACATCTTGAAAATATGGAGCAATTGCT
CCTTGCATTAGATTTAGCCGCCCCCGATCCCGAAGAACTAAATACCATCTTCCGTGCCGCCCATTCGATTAAAGGGGGCA
GTGGAATCTTTGGTTTTACCGCGCTGACCAGTGTGACTCACGTAATGGAGAATTTGCTCGATAAAACCCGAAAGGGCACG
TTTGAGCTGTCATCCTCCGTCATTGATCTCTTGCTTCGTACCGTCGATACCCTGTCGCATATTTTAAATCTCTATCGAGA
GGAAGAACCTATCGATTGGCAACAGGTGGAGTTTGCTAAAAACCAGTTAGTGGCGGCGTTAAATGGTGAGCCGTTTTCGA
CCCAGGCGGCCAAGGTTGTCGAGACCGCTAACCAAGAGAAACCTGCTGCGGTATCAACCAATTCGGCATCACAAGAAGAT
GCGAGTTTTGGTTTTTTTGAAGATGAAGTCGAGCTGGGGCTGGTCGATGAAACGGAACATTTCGGCTTTTTTGACGAGGC
TTATACCGCAAAGGAAATCCGCGTCGAGGATATTCATTCAAACGCTGCAGATTCCGCAACCCATGCTGCTGTGAGTGACG
ATGAATTAGGTTACGGCTTTTTTGAATCACTGACAGCAGAGAGTTTTGCAAATGAGTTGGACGCGTTATCAACACCGATT
CAGAATGTGCAAGTAACTGATAAGCCGGTATATAAAACCTTGGTTGAACAATCTGACGCCAAAACGGCTCGTTCAAAAAA
GCCGCCTAAAGACAGCGCCCAACTTAAATCTCAAGCGACTACGGATGTAAAACTGGAGGCGCAAACCCATTTAGCTTCAT
CCCCTGCGATGAATACGACATCAGCAACACCAGCTGCCTCTAGCCAAGTGGCGAAAAAGGCGAGCACATCGACTCAAGAT
GCCACCTTGAGGGTGGAAACCTCCAAGATAGATACCTTAGTTAATCTGGCGGGTGAATTGGTGATCACCCAATCCATGCT
CACTCTTATAGGCAATGAACTGGGCGGTGAATTAGGTGAGCGGCTTAAAACCGCGCTCAATGAGTTAGAGCGCAATACCC
GGGAAATGCAGGAAGCCGTGATGTCGGTGCGCATGTTACCCGTGTCGTTCGTGTTTAACCGTTTCCATCGTTTGGTGCGG
GATTTGTCGGAGCAGCTTGGCAAAAATGTCACTCTGGTGATTGAAGGCGGTAACACTGAAATTGATAAGGGAATGATCGA
AAAGTTGGTCGACCCTTTGACCCATCTCGTACGCAACAGTCTAGACCATGGTATTGAAAAGCCAGAAAAAAGAGTCGCGG
CAGGTAAAAGTGAGGTCGGTGTGTTGTCCCTTAAGGCGAGTCAGCGTGGCGGCAGTATAGTGATCGCCGTTCACGATGAT
GGCGGCGGTTTAAACCGCGAGCGCATTTTGCAAAAGGCCCGGGAAAATGGCATGGCACTGCCTGAGAACATGACGGACAA
GCAAGTATGGCAATTGATCTTTGCCGCGGGGTTCTCAACGGCCGCTGAGGTCACCGATGTCTCTGGTCGCGGCGTGGGTA
TGGATGTGGTGCGCAAGAATATTGAGGCCTTAGGCGGTCGCATCGATATTGATTCCGTTGCGGGCGAGGGCGCGACCTTC
GAAATCCAGCTTCCTCTTACCTTAGCCATAGTCGATGGCATGAGTGTCAGCGTGGGCAATCAAATCTATATCTTGCCCTT
AGTGCACATTATTGAATCGATACAGCCACAAACCGAGCAGCTTAAATTTTTGGCTAAAGAGCGGTTACTCAGGGTGCGGG
AAGAATATTTACCCCTGCTAAACCTCTATCAATTAATGGAAATAGAACCCCAAGCCAAGACGCCAGAAGCCGGCATAGTG
GTCTTGCTCGAAAGCAATAATAAACGCTTTGGCCTGTGTGTCGATGCACTCGTCGGGCAGCAACAAGTGGTGATCAAGAG
CCTTGAAAAACACTATCGGCGGATCCCCGGTGTATCGGGGGCGACCATCATGGGCGATGGCAGCGTGGCCTTGATCCTCG
ATGTTGAATCACTTGCACTGCATATCAAAAATTAA

Upstream 100 bases:

>100_bases
AGCCGCTGGCGCCACGGGATGGATGGTCAAGCCCTTTGACCCCCAAAAGTTATTAGCTATCACAGCCAAAGTGCTGGGCT
AACTTAGGTCGGGGTGTGCT

Downstream 100 bases:

>100_bases
CTAAGGATGTCGCAATGGATAACCGCACGAACACGGCGAGTAAGCAGGAATATAGCGTCCACGATGAGGTCGAGTTTTTA
AGCTTTGTGCTGGGTGAAGA

Product: CheA signal transduction histidine kinases

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MSINMAEFHQVFFEESHEHLENMEQLLLALDLAAPDPEELNTIFRAAHSIKGGSGIFGFTALTSVTHVMENLLDKTRKGT
FELSSSVIDLLLRTVDTLSHILNLYREEEPIDWQQVEFAKNQLVAALNGEPFSTQAAKVVETANQEKPAAVSTNSASQED
ASFGFFEDEVELGLVDETEHFGFFDEAYTAKEIRVEDIHSNAADSATHAAVSDDELGYGFFESLTAESFANELDALSTPI
QNVQVTDKPVYKTLVEQSDAKTARSKKPPKDSAQLKSQATTDVKLEAQTHLASSPAMNTTSATPAASSQVAKKASTSTQD
ATLRVETSKIDTLVNLAGELVITQSMLTLIGNELGGELGERLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFHRLVR
DLSEQLGKNVTLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRVAAGKSEVGVLSLKASQRGGSIVIAVHDD
GGGLNRERILQKARENGMALPENMTDKQVWQLIFAAGFSTAAEVTDVSGRGVGMDVVRKNIEALGGRIDIDSVAGEGATF
EIQLPLTLAIVDGMSVSVGNQIYILPLVHIIESIQPQTEQLKFLAKERLLRVREEYLPLLNLYQLMEIEPQAKTPEAGIV
VLLESNNKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLALHIKN

Sequences:

>Translated_704_residues
MSINMAEFHQVFFEESHEHLENMEQLLLALDLAAPDPEELNTIFRAAHSIKGGSGIFGFTALTSVTHVMENLLDKTRKGT
FELSSSVIDLLLRTVDTLSHILNLYREEEPIDWQQVEFAKNQLVAALNGEPFSTQAAKVVETANQEKPAAVSTNSASQED
ASFGFFEDEVELGLVDETEHFGFFDEAYTAKEIRVEDIHSNAADSATHAAVSDDELGYGFFESLTAESFANELDALSTPI
QNVQVTDKPVYKTLVEQSDAKTARSKKPPKDSAQLKSQATTDVKLEAQTHLASSPAMNTTSATPAASSQVAKKASTSTQD
ATLRVETSKIDTLVNLAGELVITQSMLTLIGNELGGELGERLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFHRLVR
DLSEQLGKNVTLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRVAAGKSEVGVLSLKASQRGGSIVIAVHDD
GGGLNRERILQKARENGMALPENMTDKQVWQLIFAAGFSTAAEVTDVSGRGVGMDVVRKNIEALGGRIDIDSVAGEGATF
EIQLPLTLAIVDGMSVSVGNQIYILPLVHIIESIQPQTEQLKFLAKERLLRVREEYLPLLNLYQLMEIEPQAKTPEAGIV
VLLESNNKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLALHIKN
>Mature_703_residues
SINMAEFHQVFFEESHEHLENMEQLLLALDLAAPDPEELNTIFRAAHSIKGGSGIFGFTALTSVTHVMENLLDKTRKGTF
ELSSSVIDLLLRTVDTLSHILNLYREEEPIDWQQVEFAKNQLVAALNGEPFSTQAAKVVETANQEKPAAVSTNSASQEDA
SFGFFEDEVELGLVDETEHFGFFDEAYTAKEIRVEDIHSNAADSATHAAVSDDELGYGFFESLTAESFANELDALSTPIQ
NVQVTDKPVYKTLVEQSDAKTARSKKPPKDSAQLKSQATTDVKLEAQTHLASSPAMNTTSATPAASSQVAKKASTSTQDA
TLRVETSKIDTLVNLAGELVITQSMLTLIGNELGGELGERLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFHRLVRD
LSEQLGKNVTLVIEGGNTEIDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRVAAGKSEVGVLSLKASQRGGSIVIAVHDDG
GGLNRERILQKARENGMALPENMTDKQVWQLIFAAGFSTAAEVTDVSGRGVGMDVVRKNIEALGGRIDIDSVAGEGATFE
IQLPLTLAIVDGMSVSVGNQIYILPLVHIIESIQPQTEQLKFLAKERLLRVREEYLPLLNLYQLMEIEPQAKTPEAGIVV
LLESNNKRFGLCVDALVGQQQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLALHIKN

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=408, Percent_Identity=53.6764705882353, Blast_Score=439, Evalue=1e-124,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76894; Mature: 76763

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINMAEFHQVFFEESHEHLENMEQLLLALDLAAPDPEELNTIFRAAHSIKGGSGIFGFT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
ALTSVTHVMENLLDKTRKGTFELSSSVIDLLLRTVDTLSHILNLYREEEPIDWQQVEFAK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
NQLVAALNGEPFSTQAAKVVETANQEKPAAVSTNSASQEDASFGFFEDEVELGLVDETEH
HHEEEEECCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEECCHHH
FGFFDEAYTAKEIRVEDIHSNAADSATHAAVSDDELGYGFFESLTAESFANELDALSTPI
CCCHHHHCCHHHEEHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QNVQVTDKPVYKTLVEQSDAKTARSKKPPKDSAQLKSQATTDVKLEAQTHLASSPAMNTT
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEHHHHHCCCCCCCCC
SATPAASSQVAKKASTSTQDATLRVETSKIDTLVNLAGELVITQSMLTLIGNELGGELGE
CCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFHRLVRDLSEQLGKNVTLVIEGGNTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
IDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRVAAGKSEVGVLSLKASQRGGSIVIAVHDD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECC
GGGLNRERILQKARENGMALPENMTDKQVWQLIFAAGFSTAAEVTDVSGRGVGMDVVRKN
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHH
IEALGGRIDIDSVAGEGATFEIQLPLTLAIVDGMSVSVGNQIYILPLVHIIESIQPQTEQ
HHHHCCEEEEHHCCCCCCEEEEECCEEEEEECCCEECCCCEEEEHHHHHHHHHCCCHHHH
LKFLAKERLLRVREEYLPLLNLYQLMEIEPQAKTPEAGIVVLLESNNKRFGLCVDALVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHCC
QQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLALHIKN
HHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHHEEEECC
>Mature Secondary Structure 
SINMAEFHQVFFEESHEHLENMEQLLLALDLAAPDPEELNTIFRAAHSIKGGSGIFGFT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHH
ALTSVTHVMENLLDKTRKGTFELSSSVIDLLLRTVDTLSHILNLYREEEPIDWQQVEFAK
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
NQLVAALNGEPFSTQAAKVVETANQEKPAAVSTNSASQEDASFGFFEDEVELGLVDETEH
HHEEEEECCCCCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEECCHHH
FGFFDEAYTAKEIRVEDIHSNAADSATHAAVSDDELGYGFFESLTAESFANELDALSTPI
CCCHHHHCCHHHEEHHHHHCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
QNVQVTDKPVYKTLVEQSDAKTARSKKPPKDSAQLKSQATTDVKLEAQTHLASSPAMNTT
CCCEECCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEHHHHHCCCCCCCCC
SATPAASSQVAKKASTSTQDATLRVETSKIDTLVNLAGELVITQSMLTLIGNELGGELGE
CCCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLKTALNELERNTREMQEAVMSVRMLPVSFVFNRFHRLVRDLSEQLGKNVTLVIEGGNTE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCC
IDKGMIEKLVDPLTHLVRNSLDHGIEKPEKRVAAGKSEVGVLSLKASQRGGSIVIAVHDD
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEEECCCCCEEEEEEECC
GGGLNRERILQKARENGMALPENMTDKQVWQLIFAAGFSTAAEVTDVSGRGVGMDVVRKN
CCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCHHHHHHH
IEALGGRIDIDSVAGEGATFEIQLPLTLAIVDGMSVSVGNQIYILPLVHIIESIQPQTEQ
HHHHCCEEEEHHCCCCCCEEEEECCEEEEEECCCEECCCCEEEEHHHHHHHHHCCCHHHH
LKFLAKERLLRVREEYLPLLNLYQLMEIEPQAKTPEAGIVVLLESNNKRFGLCVDALVGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCEEEEHHHHHHCC
QQVVIKSLEKHYRRIPGVSGATIMGDGSVALILDVESLALHIKN
HHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEEEHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]