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The map label for this gene is ydhC [H]

Identifier: 117920506

GI number: 117920506

Start: 2467952

End: 2469223

Strand: Direct

Name: ydhC [H]

Synonym: Shewana3_2062

Alternate gene names: 117920506

Gene position: 2467952-2469223 (Clockwise)

Preceding gene: 117920499

Following gene: 117920508

Centisome position: 49.63

GC content: 45.28

Gene sequence:

>1272_bases
ATGAAAACGTCTAGTAATATCTTTGTAAATATGAAGTTTTTTATATTTTTATTCTATTTGGCCTTATTAAGCATGTTAGG
TTTTATTGCCACTGACATGTATTTGCCTGCTTTCAAAGCAATTGAAAGTTCGTTTAATTCTACACCGTCTCAAGTGGCGA
TGTCGCTCACCTGTTTCTTGGCTGGTTTAGCCTTAGGGCAACTGATTTATGGCCCTTTGGTCAGTAAACTCGGCAAACGT
TATGCTCTTATTCTCGGCCTCGGCATTTTTGCGCTTGCCAGTGTGGCCATCGCCAATAGCGACTCGATACTGATGCTGAA
CATCGCTCGCTTCTTCCAAGCCGTAGGCGCCTGTAGTGCAGGGGTCATCTGGCAAGCAATTGTGGTCGAACAGTATGATG
CCGAAAAAGCGCAGGGGATTTTCAGTAACATTATGCCGTTAGTGGCATTATCACCCGCATTAGCCCCCATCCTTGGCGCT
TATATTCTGAACGATTTTGGATGGCGTGCAATCTTTATCTCATTGTGTGTGATTGCCTTTTTGTTGGTATTGATGACCTT
ATACTTTGTGCCGAGCCACGCAGAGCATCAGGATACTAGGCCAAGCGCGGTTTCCTACGGGCAGATTTTGAAAAATACTC
GTTACCTTGGCAATGTGGTGATATTTGGTGCCTGTTCGGGTGCGTTTTTCGCATATCTTACTGTGTGGCCGATTGTGATG
GAGCAACACGGCTATCAGGCAACTGAGATTGGGCTGAGCTTTATTCCGCAAACCATCATGTTTATTGTGGGCGGATACGC
GAGTAAGTTATTGATAAAACGCATTGGTGCCGACCGTACACTCAACGTATTACTGGCCATTTTTGGACTCTGCGTTATCT
CAATTGTGTTTTTCACCTTATTAATGAAGGCGGAAACTATTTTCCCACTGCTGATTTCCTTCTCGATACTCGCAGCGGCG
AACGGGGCGATTTATCCCATTGTGGTAAACAGTGCTTTGCAGCAATTCACTCAAAATGCGGCTAAGGCGGCAGGATTACA
GAACTTTTTGCAAATTACCATCGCCTTTGGCGCTTCAAGTTTAGTCGCGCTCTGGGCAAGTTCAGGAGAAGTCGCCATAG
GTTGGGGGATTCTGAGCTGTTCATTAGTAGTGATCTTAGGTTACCTGTTAAAAACCGAGCAAACTTGGGCTGATTTTGCC
AAACACTTTACTGCGCCGGATCCTGCTCGTCTTGGGATCAATGCAGATACGAAGCAAAATCAAGCAGATTGA

Upstream 100 bases:

>100_bases
TGATGAAAATAATTGATAGCATCTGTCAAAAATAAACGTTTCCAATCAAATTAACAAGTATTTAGACTGCACGCCTTAAG
TCTTTTGACATGATTATTTT

Downstream 100 bases:

>100_bases
ATGTAATACGAGCAGTTAGCGCAGAATTATCAGTTAGTGCTTTACAGTCCGTAAACTAACTTATATTATGCGCATCGTTC
GGAGGGGTGGCAGAGTGGTT

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKTSSNIFVNMKFFIFLFYLALLSMLGFIATDMYLPAFKAIESSFNSTPSQVAMSLTCFLAGLALGQLIYGPLVSKLGKR
YALILGLGIFALASVAIANSDSILMLNIARFFQAVGACSAGVIWQAIVVEQYDAEKAQGIFSNIMPLVALSPALAPILGA
YILNDFGWRAIFISLCVIAFLLVLMTLYFVPSHAEHQDTRPSAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EQHGYQATEIGLSFIPQTIMFIVGGYASKLLIKRIGADRTLNVLLAIFGLCVISIVFFTLLMKAETIFPLLISFSILAAA
NGAIYPIVVNSALQQFTQNAAKAAGLQNFLQITIAFGASSLVALWASSGEVAIGWGILSCSLVVILGYLLKTEQTWADFA
KHFTAPDPARLGINADTKQNQAD

Sequences:

>Translated_423_residues
MKTSSNIFVNMKFFIFLFYLALLSMLGFIATDMYLPAFKAIESSFNSTPSQVAMSLTCFLAGLALGQLIYGPLVSKLGKR
YALILGLGIFALASVAIANSDSILMLNIARFFQAVGACSAGVIWQAIVVEQYDAEKAQGIFSNIMPLVALSPALAPILGA
YILNDFGWRAIFISLCVIAFLLVLMTLYFVPSHAEHQDTRPSAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EQHGYQATEIGLSFIPQTIMFIVGGYASKLLIKRIGADRTLNVLLAIFGLCVISIVFFTLLMKAETIFPLLISFSILAAA
NGAIYPIVVNSALQQFTQNAAKAAGLQNFLQITIAFGASSLVALWASSGEVAIGWGILSCSLVVILGYLLKTEQTWADFA
KHFTAPDPARLGINADTKQNQAD
>Mature_423_residues
MKTSSNIFVNMKFFIFLFYLALLSMLGFIATDMYLPAFKAIESSFNSTPSQVAMSLTCFLAGLALGQLIYGPLVSKLGKR
YALILGLGIFALASVAIANSDSILMLNIARFFQAVGACSAGVIWQAIVVEQYDAEKAQGIFSNIMPLVALSPALAPILGA
YILNDFGWRAIFISLCVIAFLLVLMTLYFVPSHAEHQDTRPSAVSYGQILKNTRYLGNVVIFGACSGAFFAYLTVWPIVM
EQHGYQATEIGLSFIPQTIMFIVGGYASKLLIKRIGADRTLNVLLAIFGLCVISIVFFTLLMKAETIFPLLISFSILAAA
NGAIYPIVVNSALQQFTQNAAKAAGLQNFLQITIAFGASSLVALWASSGEVAIGWGILSCSLVVILGYLLKTEQTWADFA
KHFTAPDPARLGINADTKQNQAD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=379, Percent_Identity=41.9525065963061, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1788509, Length=270, Percent_Identity=29.2592592592593, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1790146, Length=246, Percent_Identity=25.609756097561, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787065, Length=295, Percent_Identity=24.0677966101695, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1790794, Length=239, Percent_Identity=24.2677824267782, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082312, Length=363, Percent_Identity=21.763085399449, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45699; Mature: 45699

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]