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The map label for this gene is lolA [H]

Identifier: 117920495

GI number: 117920495

Start: 2460741

End: 2461361

Strand: Direct

Name: lolA [H]

Synonym: Shewana3_2051

Alternate gene names: 117920495

Gene position: 2460741-2461361 (Clockwise)

Preceding gene: 117920494

Following gene: 117920496

Centisome position: 49.49

GC content: 45.25

Gene sequence:

>621_bases
ATGAAAAAACTGTTGTGTGCTGTGTTGTTATCACCATTGTTATACAGCAATGCAGTATTGGCCGATGACGCAAAGCAATT
ACGCGAAACCTTAAACGGCACTGAGTCACTCAAGGCGGATTTCAAGCAAACCGTTACCGATATCAATAAAAAGGTTATCC
AAACGGGCGCGGGTGTATTCGCGCTTGCCCATCCAAACCAGTTCTATTGGCATTTAACCGCGCCCGATGAATCCCAAATT
GTCGCCGACGGTAAAGATTTATGGATTTATAATCCCTTCGCCGAAGAAGTGGTGATCATGGATTTTGCTGAAGCCATTAA
TGCATCGCCGATCGCCTTATTGGTTCACCGCGATGACGCCACTTGGTCACAATATAGCGTCGCCAAGAAGCAAGACTGTT
ATGAAATCAAACCTAAGGCCACGGATGCCGGGATCTCCTCGGTCAATGTCTGTTTTAACAAAGGCACGCTGAATAAATTC
AATGTGCTCGATGATAAAGGCAACCAGAGCCAGTTTGATTTGAGCAATCAACACAGCATTAGCGCCGCGGATAAAGCGTT
ATTTAAGTTCGTGTTGCCAGAAAACGTTGATGTGGATGATCAACGTCTTAAAAGCCAGTAG

Upstream 100 bases:

>100_bases
GCTGGCACCGCCGGCCCCGAAACACTATTAATGTTAAGCTAGATGTCAGTTTGAACTCGCCATAATGCGGCGAGTTCAAC
TTTTAGTCCAAAGGATACCT

Downstream 100 bases:

>100_bases
GTTTACGCGTGAGCAGTTTATCGTTTAATTTTGCGCCTGATTTTCGTCCCTTAGCCGCGCGTATGCGGCCAAGGACGATT
GCCGAGTATATAGGTCAAGC

Product: outer membrane lipoprotein carrier protein LolA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MKKLLCAVLLSPLLYSNAVLADDAKQLRETLNGTESLKADFKQTVTDINKKVIQTGAGVFALAHPNQFYWHLTAPDESQI
VADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVAKKQDCYEIKPKATDAGISSVNVCFNKGTLNKF
NVLDDKGNQSQFDLSNQHSISAADKALFKFVLPENVDVDDQRLKSQ

Sequences:

>Translated_206_residues
MKKLLCAVLLSPLLYSNAVLADDAKQLRETLNGTESLKADFKQTVTDINKKVIQTGAGVFALAHPNQFYWHLTAPDESQI
VADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVAKKQDCYEIKPKATDAGISSVNVCFNKGTLNKF
NVLDDKGNQSQFDLSNQHSISAADKALFKFVLPENVDVDDQRLKSQ
>Mature_206_residues
MKKLLCAVLLSPLLYSNAVLADDAKQLRETLNGTESLKADFKQTVTDINKKVIQTGAGVFALAHPNQFYWHLTAPDESQI
VADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDATWSQYSVAKKQDCYEIKPKATDAGISSVNVCFNKGTLNKF
NVLDDKGNQSQFDLSNQHSISAADKALFKFVLPENVDVDDQRLKSQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family [H]

Homologues:

Organism=Escherichia coli, GI145693108, Length=205, Percent_Identity=35.609756097561, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004564
- InterPro:   IPR018323 [H]

Pfam domain/function: PF03548 LolA [H]

EC number: NA

Molecular weight: Translated: 22867; Mature: 22867

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLLCAVLLSPLLYSNAVLADDAKQLRETLNGTESLKADFKQTVTDINKKVIQTGAGVF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
ALAHPNQFYWHLTAPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDA
EEECCCEEEEEEECCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCC
TWSQYSVAKKQDCYEIKPKATDAGISSVNVCFNKGTLNKFNVLDDKGNQSQFDLSNQHSI
CCHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCH
SAADKALFKFVLPENVDVDDQRLKSQ
HHHHHHHHHHCCCCCCCCCHHHHCCC
>Mature Secondary Structure
MKKLLCAVLLSPLLYSNAVLADDAKQLRETLNGTESLKADFKQTVTDINKKVIQTGAGVF
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
ALAHPNQFYWHLTAPDESQIVADGKDLWIYNPFAEEVVIMDFAEAINASPIALLVHRDDA
EEECCCEEEEEEECCCCCEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCC
TWSQYSVAKKQDCYEIKPKATDAGISSVNVCFNKGTLNKFNVLDDKGNQSQFDLSNQHSI
CCHHHHHHHCCCCEECCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCH
SAADKALFKFVLPENVDVDDQRLKSQ
HHHHHHHHHHCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]