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The map label for this gene is trxB [H]

Identifier: 117920491

GI number: 117920491

Start: 2454590

End: 2455543

Strand: Reverse

Name: trxB [H]

Synonym: Shewana3_2047

Alternate gene names: 117920491

Gene position: 2455543-2454590 (Counterclockwise)

Preceding gene: 117920492

Following gene: 117920486

Centisome position: 49.39

GC content: 48.43

Gene sequence:

>954_bases
ATGAGCCAAGTCAGACACAGTAACCTATTGATTTTAGGTTCAGGTCCCGCAGGATACACGGCCGCAGTTTATGCTGCGCG
CGCAAACTTAAAGCCTGTGATGATTACAGGTATGCAGCAAGGTGGTCAGTTAACCACCACGACTGAAGTTGAAAACTGGC
CAGGTGATGCAGAAGACTTAACGGGTCCAGCATTAATGGAACGTATGCAAAAGCATGCGGAAAAGTTTGATACTGAAATC
CTTTTCGACCATATCAATGAAGTCACACTGACTGAGCGCCCTTTCCGTCTAAAAGGCGATAACGGTGAATACACCTGTGA
TGCGCTGATCATTGCGACAGGCGCCTCAGCTCGTTACTTAGGTCTGGAGTCAGAAGAAGCGTTCAAAGGACGCGGCGTAT
CGGCTTGTGCGACCTGTGATGGTTTCTTCTATCGCAATCAGAAAGTTGCAGTCATTGGTGGTGGTAACACAGCCGTTGAA
GAAGCGCTGTATTTGAGTAACATCGCCGCCGAAGTGCACTTAATTCATCGCCGTGACACCTTCCGCTCAGAGAAAATCCT
TATCGACCGTTTAATGGATAAAGTAGCTAACGGCAACATTATCCTGCACCTAGATCAAACCATGGAAGAAGTGGTTGGTG
ACGCTATGGGTGTGACAGGCCTGAAAATGAAGAGCACCAAAGATGGCGCTATCACAGATCTGGCTGTTGCCGGTGTGTTC
GTGGCCATTGGTCACAGCCCAAATACTGGGATTTTCGAAGGCCAGTTAGAGATGAACAACGGTTATCTGAAGGTGCAAAG
CGGCCTTCAAGGTAATGCGACCCAAACCAGCATTGAAGGTGTGTTTGCCGCGGGTGACGTTATGGACCAACATTACCGTC
AAGCGATTACCTCTGCGGGTACCGGTTGTATGGCAGCATTAGATGCTGAGCGTTACTTAGACGCTAAAAAATAA

Upstream 100 bases:

>100_bases
ATTCGATTAGCATAATCTAAAAGAATCACCAAACAGCGCTTTACCCCTACAGGTAAATTCCCTACAATCCATGCAATTTG
CTAAAGGCACGGAGAGAAAA

Downstream 100 bases:

>100_bases
TCACGCGCAGAAACCATCGGATCTGGTTCTTAGTTTTAGCGAGATTCAAATAGAAATAGCAGGCATCAGCCTGCTATTTT
TTTATCTGTATTTTGTGACT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSQVRHSNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFDTEI
LFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIAAEVHLIHRRDTFRSEKILIDRLMDKVANGNIILHLDQTMEEVVGDAMGVTGLKMKSTKDGAITDLAVAGVF
VAIGHSPNTGIFEGQLEMNNGYLKVQSGLQGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAKK

Sequences:

>Translated_317_residues
MSQVRHSNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFDTEI
LFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIAAEVHLIHRRDTFRSEKILIDRLMDKVANGNIILHLDQTMEEVVGDAMGVTGLKMKSTKDGAITDLAVAGVF
VAIGHSPNTGIFEGQLEMNNGYLKVQSGLQGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAKK
>Mature_316_residues
SQVRHSNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDAEDLTGPALMERMQKHAEKFDTEIL
FDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYLGLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEE
ALYLSNIAAEVHLIHRRDTFRSEKILIDRLMDKVANGNIILHLDQTMEEVVGDAMGVTGLKMKSTKDGAITDLAVAGVFV
AIGHSPNTGIFEGQLEMNNGYLKVQSGLQGNATQTSIEGVFAAGDVMDQHYRQAITSAGTGCMAALDAERYLDAKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=81.9047619047619, Blast_Score=538, Evalue=1e-154,
Organism=Escherichia coli, GI87081763, Length=315, Percent_Identity=33.3333333333333, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=46.8085106382979, Blast_Score=287, Evalue=1e-78,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=45.9375, Blast_Score=273, Evalue=2e-74,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34100; Mature: 33969

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVRHSNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDAEDL
CCCCCCCCEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHC
TGPALMERMQKHAEKFDTEILFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIAAEVHLIHRRDT
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILIDRLMDKVANGNIILHLDQTMEEVVGDAMGVTGLKMKSTKDGAITDLAVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHEEEE
VAIGHSPNTGIFEGQLEMNNGYLKVQSGLQGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAKK
CCCEEECCHHHHCCCCC
>Mature Secondary Structure 
SQVRHSNLLILGSGPAGYTAAVYAARANLKPVMITGMQQGGQLTTTTEVENWPGDAEDL
CCCCCCCEEEEECCCCCCHHEEEEHHCCCCEEEEECCCCCCEEEEEEECCCCCCCHHHC
TGPALMERMQKHAEKFDTEILFDHINEVTLTERPFRLKGDNGEYTCDALIIATGASARYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCCCEEEEEEEEEECCCEEEE
GLESEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIAAEVHLIHRRDT
CCCCCHHHCCCCCEEEEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHEEEEEECCCC
FRSEKILIDRLMDKVANGNIILHLDQTMEEVVGDAMGVTGLKMKSTKDGAITDLAVAGVF
CCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHEEEE
VAIGHSPNTGIFEGQLEMNNGYLKVQSGLQGNATQTSIEGVFAAGDVMDQHYRQAITSAG
EEECCCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHCEEEEHHHHHHHHHHHHHHHCC
TGCMAALDAERYLDAKK
CCCEEECCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]