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The map label for this gene is hsdS [C]

Identifier: 117920473

GI number: 117920473

Start: 2425817

End: 2426992

Strand: Direct

Name: hsdS [C]

Synonym: Shewana3_2028

Alternate gene names: 117920473

Gene position: 2425817-2426992 (Clockwise)

Preceding gene: 117920472

Following gene: 117920474

Centisome position: 48.79

GC content: 41.67

Gene sequence:

>1176_bases
ATGGTAAAGTTGGGCGATATTTTTGATATAGCTAGGGGAGGATCGCCTCGCCCTATCGACGACTATATAACCGATGCCGA
TGACGGGTTAAATTGGATATCCATAAAAGACGCTAGTAACAGTAATAAATACATTAATTCAACAAAACTAAAAATTAAAC
CTGAAGGTTTAACTAAAACTCGTATGGTTTATCCAGGCGATTTTTTGCTGACAAACTCTATGAGTTTTGGACGGCCATAT
ATTATGAATACTACGGGATGTATTCATGACGGATGGTTAGTACTATCAGGGAATCCGGATAAAGTTAATTCGGATTATTT
CTACTATTTACTAGGAAGCGATACTTTAAAACAACGTTTTTCTGGATTAGCAGCTGGTGCTGTTGTCAAAAACCTCAATA
CTGAATTAGTTAAAAGTGTGGAAGTCCCACTCCCACCACTAGCCGAGCAAAAACGGATTGCTGCGATACTGGACAAAGCC
GACGCCATCCGCCGCAAACGCCAACAAGCCATCCAACTCGCCGACGACTTACTCCGCGCCGTCTTCCTAGAAATGTTCGG
CGACCCAGTCACCAACCCAAAAGGCTTTCAGAAGTCAAAATTGTCGGCTCTTGCCGACGTTATTACTGGATTTGCGTTTA
AAAGCGCTGAGTATGTCGAAGACAGTGATGATGCTGTAAGGCTTTGTCGTGGGGTTAATACACTGACTGGCTATTTTGAG
TGGAAAGATACTGCTTTTTGGGATTCAAATAAAATAAATGGGCTACACAATTACAAACTAGAAGCTGGCGACGTGATACT
AGCTATGGACCGTCCATGGATTTCAAGTGGATTAAAGGTATGTGTCTTCCCTGAAAACGAGCGAGATACATATTTAGTTC
AACGTGTAGCAAGAATCCGCTCAAAACAGCCACGTTATACCGATTATTTGTATTCAAGCATTTTGTCACCGGCATTTGAG
AAGCATTGCTGTCCTACAGAAACAACAGTCCCTCATATTTCGCCAGTTGAACTAAAGAACTTTGAGATTCTGGTACCTGA
TGAAAAATCAGTTAGCAAATATCACGATATAGTCTCTAAGTTAAGGCGCTCGAAAGATCGAATGGAAATGAACTTGACTG
AGGCTAATCAAATCTTCAACTCGCTAAGCCAAAAAGCCTTCTCCGGCCAGCTTTAG

Upstream 100 bases:

>100_bases
AGTATGACGACCCGAAAGTGATCCTTAGTAAATTAGTGGCGCTGGAAAACGATATTCTGGCGGATTTAAAAGCGTTGGAG
GATATGCTGTGAGTTGGCCG

Downstream 100 bases:

>100_bases
TAAATTCTCAAGGACGAAACCGTGTCAGAAAAATTCAGCCTTTACGACATCTATGAGCAAAATTTAAACTTTCTTTTTGG
CGCTGGCGCCTCTTATGGTT

Product: restriction modification system DNA specificity subunit

Products: NA

Alternate protein names: S.MjaXIP; Type I restriction enzyme MjaXIP specificity protein; S protein [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MVKLGDIFDIARGGSPRPIDDYITDADDGLNWISIKDASNSNKYINSTKLKIKPEGLTKTRMVYPGDFLLTNSMSFGRPY
IMNTTGCIHDGWLVLSGNPDKVNSDYFYYLLGSDTLKQRFSGLAAGAVVKNLNTELVKSVEVPLPPLAEQKRIAAILDKA
DAIRRKRQQAIQLADDLLRAVFLEMFGDPVTNPKGFQKSKLSALADVITGFAFKSAEYVEDSDDAVRLCRGVNTLTGYFE
WKDTAFWDSNKINGLHNYKLEAGDVILAMDRPWISSGLKVCVFPENERDTYLVQRVARIRSKQPRYTDYLYSSILSPAFE
KHCCPTETTVPHISPVELKNFEILVPDEKSVSKYHDIVSKLRRSKDRMEMNLTEANQIFNSLSQKAFSGQL

Sequences:

>Translated_391_residues
MVKLGDIFDIARGGSPRPIDDYITDADDGLNWISIKDASNSNKYINSTKLKIKPEGLTKTRMVYPGDFLLTNSMSFGRPY
IMNTTGCIHDGWLVLSGNPDKVNSDYFYYLLGSDTLKQRFSGLAAGAVVKNLNTELVKSVEVPLPPLAEQKRIAAILDKA
DAIRRKRQQAIQLADDLLRAVFLEMFGDPVTNPKGFQKSKLSALADVITGFAFKSAEYVEDSDDAVRLCRGVNTLTGYFE
WKDTAFWDSNKINGLHNYKLEAGDVILAMDRPWISSGLKVCVFPENERDTYLVQRVARIRSKQPRYTDYLYSSILSPAFE
KHCCPTETTVPHISPVELKNFEILVPDEKSVSKYHDIVSKLRRSKDRMEMNLTEANQIFNSLSQKAFSGQL
>Mature_391_residues
MVKLGDIFDIARGGSPRPIDDYITDADDGLNWISIKDASNSNKYINSTKLKIKPEGLTKTRMVYPGDFLLTNSMSFGRPY
IMNTTGCIHDGWLVLSGNPDKVNSDYFYYLLGSDTLKQRFSGLAAGAVVKNLNTELVKSVEVPLPPLAEQKRIAAILDKA
DAIRRKRQQAIQLADDLLRAVFLEMFGDPVTNPKGFQKSKLSALADVITGFAFKSAEYVEDSDDAVRLCRGVNTLTGYFE
WKDTAFWDSNKINGLHNYKLEAGDVILAMDRPWISSGLKVCVFPENERDTYLVQRVARIRSKQPRYTDYLYSSILSPAFE
KHCCPTETTVPHISPVELKNFEILVPDEKSVSKYHDIVSKLRRSKDRMEMNLTEANQIFNSLSQKAFSGQL

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 44023; Mature: 44023

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKLGDIFDIARGGSPRPIDDYITDADDGLNWISIKDASNSNKYINSTKLKIKPEGLTKT
CCCCCCHHHHHCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCEEECEEEEEECCCCCEE
RMVYPGDFLLTNSMSFGRPYIMNTTGCIHDGWLVLSGNPDKVNSDYFYYLLGSDTLKQRF
EEECCCCEEEECCCCCCCCEEECCCCEEECCEEEEECCCCCCCCCEEEEEECCHHHHHHH
SGLAAGAVVKNLNTELVKSVEVPLPPLAEQKRIAAILDKADAIRRKRQQAIQLADDLLRA
HHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFLEMFGDPVTNPKGFQKSKLSALADVITGFAFKSAEYVEDSDDAVRLCRGVNTLTGYFE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCHHHEEEEE
WKDTAFWDSNKINGLHNYKLEAGDVILAMDRPWISSGLKVCVFPENERDTYLVQRVARIR
ECCCEEECCCCCCCCCCCEECCCCEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHHH
SKQPRYTDYLYSSILSPAFEKHCCPTETTVPHISPVELKNFEILVPDEKSVSKYHDIVSK
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCEEEEECCCHHHHHHHHHHHH
LRRSKDRMEMNLTEANQIFNSLSQKAFSGQL
HHHHHHHHEECHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVKLGDIFDIARGGSPRPIDDYITDADDGLNWISIKDASNSNKYINSTKLKIKPEGLTKT
CCCCCCHHHHHCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCEEECEEEEEECCCCCEE
RMVYPGDFLLTNSMSFGRPYIMNTTGCIHDGWLVLSGNPDKVNSDYFYYLLGSDTLKQRF
EEECCCCEEEECCCCCCCCEEECCCCEEECCEEEEECCCCCCCCCEEEEEECCHHHHHHH
SGLAAGAVVKNLNTELVKSVEVPLPPLAEQKRIAAILDKADAIRRKRQQAIQLADDLLRA
HHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFLEMFGDPVTNPKGFQKSKLSALADVITGFAFKSAEYVEDSDDAVRLCRGVNTLTGYFE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCHHHHHHHHCCHHHEEEEE
WKDTAFWDSNKINGLHNYKLEAGDVILAMDRPWISSGLKVCVFPENERDTYLVQRVARIR
ECCCEEECCCCCCCCCCCEECCCCEEEEECCCHHHCCCEEEEECCCCCHHHHHHHHHHHH
SKQPRYTDYLYSSILSPAFEKHCCPTETTVPHISPVELKNFEILVPDEKSVSKYHDIVSK
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCEEEEECCCHHHHHHHHHHHH
LRRSKDRMEMNLTEANQIFNSLSQKAFSGQL
HHHHHHHHEECHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]