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The map label for this gene is tcpI [H]

Identifier: 117920462

GI number: 117920462

Start: 2407242

End: 2408873

Strand: Reverse

Name: tcpI [H]

Synonym: Shewana3_2017

Alternate gene names: 117920462

Gene position: 2408873-2407242 (Counterclockwise)

Preceding gene: 117920466

Following gene: 117920458

Centisome position: 48.45

GC content: 45.59

Gene sequence:

>1632_bases
ATGCGTAATCTAAAGATCAGTCACCTATTACTTGGCGCTTTTGCGATTCCAATTATTGCAATTCTAGGGTTAACCATGAT
GGCAATGAGCAAAATGCAGGTCATCAATGATCAGTCTACCGTCATATCCAATGACTGGTTGCCAGCCGTGCGGGTCATCG
AGCGACTCAACGGTCAAACCGCAGATCTTAGGGTATTAGAATCCCGGCATATTCTCTCGCTGGATGAAGGACAGATGCGA
GATACCGAGCGTGAACTGGAGAAAACCAAAGCGCAAATCGATGACTCTATCCGCACCTACGAGCAACTGATCAGCGGCAA
TAAAGAACGAAATATCTTCAATGATTTTAAGCGCTTATATAAGGAATATCTGGTCGTTCACCAGAAGCTGCTTATACTGT
CACGGGCAAATAAAAACGAAGATGCTAAACAACTGCTGTTGACGGAATCACTCGAGGCGTATAACGAATACTCGGATTTA
TTGCTGAAATTATCAGACCTGAATTACAAAGGCGCGCAGGACGCAAGCAGCTATGGCGATGTAATTTACGATGAATCGAT
CAAAATAATGTTATTCATTTTGGTCATAGTGTCATTGCTGGTGTTAGTGACGTCGACGGCTATCTCAAAATTTATTATTA
CATCGATTAAAACCGTGCAGAGTTTTATGGCGAAATTGGCTAATGGCGATCTTTCCGATCGCATTGCCGATATTGGCAAT
AATGAATTGGGTGTTTTGGCCCAGGGCTGTAATGAGACTGCCGATAAAATCTCTGAAATGACCGAGCAATTGATTACCGT
TGCCGATAATACCGCGACTTCGGCCGAAATACTCGCCTCGACCATGAATCAAGTTGAGCATAATTCCCAGCAAATGCTGG
TGCAGGTAGAACAAATCGCGACGGCGCTCAATGAAATGTCCAGTACGGCACTGGAAGTGAGTAAAAATGCGACCGAGGCG
GAAACCAGTGCAGCTGAGGCGATGGGCAATGTCTCTGAAGGCAACAAGTCCCTCGGCGAGTCCGATAATATTTCAGTCAA
AATTGGTGCGGCGATCCGAGATTCAGGCGCCATAGTGAATCAGTTGAAAGACTATTCTATCGAAATTGGCTCAGTTATTG
ATGTGATTACCAGTATTTCCGAACAAACCAACCTACTGGCACTCAATGCGGCGATTGAAGCCGCAAGGGCTGGAGAAGCG
GGTCGCGGTTTTGCCGTAGTCGCCGATGAGGTTCGCTCTCTTGCGGCTAAAACCCAGCAATCCACCATTGATATTCAAGA
AATTATTTCAAAATTACAGTCTCAGGCGGAAAAGGCCGACCATTATATGAAGGCCAATACCAGTTTGCTGGATGAGTCAC
AAATGGTATCGGAAAAAGTCCGTAGTGCTTTCCAGGGGATTTCAGCCTCCGTCAATGCGATTTCCAATGTTAATACCGTG
GTTGCCACGGCATCGAGCGAACAATCGAGCGTGACCGAAGACATTTCCAGAAATATCTCATCGACGGTTGAAATGGTCGA
TCAAAACGTGGTTGGGATCGGCAATGCCAGTAAGGCTTGCCATGATGTGTTATCTGAAGCGGGTAAACAAAAACAGCTAC
TTGCCTTCTTCAAAACCAAGCGCAGTTATTGA

Upstream 100 bases:

>100_bases
CGAAAGTGAAGACTCTGACTTATATATCTATGGAAGGAAAAATACCTACATTAGGCTTTTTTAACTGAATTTGAGCATAG
TCATCATTGCTGGGGTTTAC

Downstream 100 bases:

>100_bases
TTAGAGAATAGATGTATCCAGTGGGGCGATTGTGAGTTAAAGCGAACCACTGAACGTTAGTACACTTGAGATTTAGCGCA
GCCTAGGTTATTGGAGCCTA

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: TCP pilus biosynthesis protein tcpI [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MRNLKISHLLLGAFAIPIIAILGLTMMAMSKMQVINDQSTVISNDWLPAVRVIERLNGQTADLRVLESRHILSLDEGQMR
DTERELEKTKAQIDDSIRTYEQLISGNKERNIFNDFKRLYKEYLVVHQKLLILSRANKNEDAKQLLLTESLEAYNEYSDL
LLKLSDLNYKGAQDASSYGDVIYDESIKIMLFILVIVSLLVLVTSTAISKFIITSIKTVQSFMAKLANGDLSDRIADIGN
NELGVLAQGCNETADKISEMTEQLITVADNTATSAEILASTMNQVEHNSQQMLVQVEQIATALNEMSSTALEVSKNATEA
ETSAAEAMGNVSEGNKSLGESDNISVKIGAAIRDSGAIVNQLKDYSIEIGSVIDVITSISEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRSLAAKTQQSTIDIQEIISKLQSQAEKADHYMKANTSLLDESQMVSEKVRSAFQGISASVNAISNVNTV
VATASSEQSSVTEDISRNISSTVEMVDQNVVGIGNASKACHDVLSEAGKQKQLLAFFKTKRSY

Sequences:

>Translated_543_residues
MRNLKISHLLLGAFAIPIIAILGLTMMAMSKMQVINDQSTVISNDWLPAVRVIERLNGQTADLRVLESRHILSLDEGQMR
DTERELEKTKAQIDDSIRTYEQLISGNKERNIFNDFKRLYKEYLVVHQKLLILSRANKNEDAKQLLLTESLEAYNEYSDL
LLKLSDLNYKGAQDASSYGDVIYDESIKIMLFILVIVSLLVLVTSTAISKFIITSIKTVQSFMAKLANGDLSDRIADIGN
NELGVLAQGCNETADKISEMTEQLITVADNTATSAEILASTMNQVEHNSQQMLVQVEQIATALNEMSSTALEVSKNATEA
ETSAAEAMGNVSEGNKSLGESDNISVKIGAAIRDSGAIVNQLKDYSIEIGSVIDVITSISEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRSLAAKTQQSTIDIQEIISKLQSQAEKADHYMKANTSLLDESQMVSEKVRSAFQGISASVNAISNVNTV
VATASSEQSSVTEDISRNISSTVEMVDQNVVGIGNASKACHDVLSEAGKQKQLLAFFKTKRSY
>Mature_543_residues
MRNLKISHLLLGAFAIPIIAILGLTMMAMSKMQVINDQSTVISNDWLPAVRVIERLNGQTADLRVLESRHILSLDEGQMR
DTERELEKTKAQIDDSIRTYEQLISGNKERNIFNDFKRLYKEYLVVHQKLLILSRANKNEDAKQLLLTESLEAYNEYSDL
LLKLSDLNYKGAQDASSYGDVIYDESIKIMLFILVIVSLLVLVTSTAISKFIITSIKTVQSFMAKLANGDLSDRIADIGN
NELGVLAQGCNETADKISEMTEQLITVADNTATSAEILASTMNQVEHNSQQMLVQVEQIATALNEMSSTALEVSKNATEA
ETSAAEAMGNVSEGNKSLGESDNISVKIGAAIRDSGAIVNQLKDYSIEIGSVIDVITSISEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRSLAAKTQQSTIDIQEIISKLQSQAEKADHYMKANTSLLDESQMVSEKVRSAFQGISASVNAISNVNTV
VATASSEQSSVTEDISRNISSTVEMVDQNVVGIGNASKACHDVLSEAGKQKQLLAFFKTKRSY

Specific function: May function as an environmental regulator of TCP biogenesis. Negatively regulates the synthesis of the major pilin subunit of TCP (tcpA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=360, Percent_Identity=28.6111111111111, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI2367378, Length=363, Percent_Identity=26.7217630853994, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788195, Length=303, Percent_Identity=26.4026402640264, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788194, Length=362, Percent_Identity=25.9668508287293, Blast_Score=96, Evalue=8e-21,
Organism=Escherichia coli, GI1789453, Length=248, Percent_Identity=27.8225806451613, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 59121; Mature: 59121

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNLKISHLLLGAFAIPIIAILGLTMMAMSKMQVINDQSTVISNDWLPAVRVIERLNGQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCC
ADLRVLESRHILSLDEGQMRDTERELEKTKAQIDDSIRTYEQLISGNKERNIFNDFKRLY
HHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
KEYLVVHQKLLILSRANKNEDAKQLLLTESLEAYNEYSDLLLKLSDLNYKGAQDASSYGD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCC
VIYDESIKIMLFILVIVSLLVLVTSTAISKFIITSIKTVQSFMAKLANGDLSDRIADIGN
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
NELGVLAQGCNETADKISEMTEQLITVADNTATSAEILASTMNQVEHNSQQMLVQVEQIA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TALNEMSSTALEVSKNATEAETSAAEAMGNVSEGNKSLGESDNISVKIGAAIRDSGAIVN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEECEECCCCHHHH
QLKDYSIEIGSVIDVITSISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAAKTQQ
HHHHCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
STIDIQEIISKLQSQAEKADHYMKANTSLLDESQMVSEKVRSAFQGISASVNAISNVNTV
HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
VATASSEQSSVTEDISRNISSTVEMVDQNVVGIGNASKACHDVLSEAGKQKQLLAFFKTK
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RSY
CCC
>Mature Secondary Structure
MRNLKISHLLLGAFAIPIIAILGLTMMAMSKMQVINDQSTVISNDWLPAVRVIERLNGQT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCC
ADLRVLESRHILSLDEGQMRDTERELEKTKAQIDDSIRTYEQLISGNKERNIFNDFKRLY
HHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
KEYLVVHQKLLILSRANKNEDAKQLLLTESLEAYNEYSDLLLKLSDLNYKGAQDASSYGD
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCC
VIYDESIKIMLFILVIVSLLVLVTSTAISKFIITSIKTVQSFMAKLANGDLSDRIADIGN
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCC
NELGVLAQGCNETADKISEMTEQLITVADNTATSAEILASTMNQVEHNSQQMLVQVEQIA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHH
TALNEMSSTALEVSKNATEAETSAAEAMGNVSEGNKSLGESDNISVKIGAAIRDSGAIVN
HHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHCCCCCCCCCCCEEEEEECEECCCCHHHH
QLKDYSIEIGSVIDVITSISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAAKTQQ
HHHHCCCHHHHHHHHHHHHHHHCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
STIDIQEIISKLQSQAEKADHYMKANTSLLDESQMVSEKVRSAFQGISASVNAISNVNTV
HCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHE
VATASSEQSSVTEDISRNISSTVEMVDQNVVGIGNASKACHDVLSEAGKQKQLLAFFKTK
EEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHH
RSY
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8005659 [H]