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The map label for this gene is cseB [H]

Identifier: 117920458

GI number: 117920458

Start: 2399717

End: 2400952

Strand: Reverse

Name: cseB [H]

Synonym: Shewana3_2013

Alternate gene names: 117920458

Gene position: 2400952-2399717 (Counterclockwise)

Preceding gene: 117920462

Following gene: 117920457

Centisome position: 48.29

GC content: 50.89

Gene sequence:

>1236_bases
ATGCCGCTCTCTTCGCTCACATCGATTCAAGCCGTTACCTTGTCTGTGCTGGTCGTGGAAGACACAGATTGCGAGCGCTT
TTATATCACTCACCTGCTAAGACAGTTTGGTTGGTTGGTCGAGAGTCGCAGTAACGGTAAGGCTGCGCTGGATTACTTGC
AGCAGAATGAAGTGCATATTTTAGTCAGCGATTGGCGCATGCCTGAGATGAGCGGCATCGAGTTGTGCCAAATCGTTAAA
AATAATCATCTGCCGCCCTTTGTGATCTTGCTGACGGCCAATAATCAGACAGCCGATATTGTGTTAGGTATTGAAGCGGG
CGCCGATGACTTTATCTGTAAGCCTTTTCTACCAGAACTGTTAAAGGTTAGGATGTTAGCTGCGATGCGTATCGTGCAGC
TGCAACATAACTTGAGCCGTAACATTCAACTGTTACAGCAAGGGCTTGCGAAAGAATCTGCCTTGCTCAGCACCATAAAA
CAGGATTTGTTTTCTGCCGCTAAGGTGCAGCGAGAATTACTGCCCCGCAGTAAAACCTTGCCAAGGGATTGGCAGTTACA
CCATGAGTTTCAGCCCGCGAGTTATCTTGCTGGCGATCTCTATCAATGTTTCGATCTTGGCGATGATCAACTCGGGTTTT
ATCTGATTGATGCCGCGGGTCATGGGGTCGCCGCCGCGCTGCAGAGTGTCAGCCTTGCCCAGCGTCTGTCGATGGAACGT
ACCGATTGGTGCGGATTATCGCCCCAAGAAATAGTGAATCAGGTTAATCGCGAGCTAAGCGACCCAGACAATACTGGCCG
CTTTGTGACTCTGTTACTCGGCAAGATCAATACGCTGACGGGTGAACTAAGGCTGTGCAGCGCCGGCCATCCCGCGCCGT
TACTGCTCACCGAGACTAGCTGCGAGCCCTTGCCCCTCGACACTGAGTTACCGCTTGGGATCCATGGCGCCGTGCAGTAT
CAAGATCAGCTAGTCACCCTCTTACCTGGCAGTCGCTTGTTGTTATTTTCCGATGGTACCTATGAGTGCCAACACCCCAA
GTTCGGTTTTTTCGGCCAAGCGCGTTTGCAAACCCTGTGCTCGAAAGCCAACAGCTTGAGCGATGAAGCCTTGCTGCATC
ACTTGAGCCATGCCTTACAACTCTGGCAAGGCGGCACAACTCAAGATGATATTTCGATGATGTTAATTACCTACCCGTCA
GCCAACTATGCCAATGCGGCTTTGGAGGCATTATGA

Upstream 100 bases:

>100_bases
TTTCGGCGATGCTTTGCAGTATCAACCTCAATTAGTTGGCTTTTTTTAAATGGGCATAGCTCTTGCTATTCGAAAATATT
CCCTTTGCAGGAGTCAGACT

Downstream 100 bases:

>100_bases
ACAGCTTGCAGTTTAACCTCACCCATGACCAATGGAGTCAACAGCCTTTTTGCTCCGAATTAGAGCAGTTTATGCTGATG
CAAAATGTACATGAGCGCCA

Product: response regulator receiver modulated serine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MPLSSLTSIQAVTLSVLVVEDTDCERFYITHLLRQFGWLVESRSNGKAALDYLQQNEVHILVSDWRMPEMSGIELCQIVK
NNHLPPFVILLTANNQTADIVLGIEAGADDFICKPFLPELLKVRMLAAMRIVQLQHNLSRNIQLLQQGLAKESALLSTIK
QDLFSAAKVQRELLPRSKTLPRDWQLHHEFQPASYLAGDLYQCFDLGDDQLGFYLIDAAGHGVAAALQSVSLAQRLSMER
TDWCGLSPQEIVNQVNRELSDPDNTGRFVTLLLGKINTLTGELRLCSAGHPAPLLLTETSCEPLPLDTELPLGIHGAVQY
QDQLVTLLPGSRLLLFSDGTYECQHPKFGFFGQARLQTLCSKANSLSDEALLHHLSHALQLWQGGTTQDDISMMLITYPS
ANYANAALEAL

Sequences:

>Translated_411_residues
MPLSSLTSIQAVTLSVLVVEDTDCERFYITHLLRQFGWLVESRSNGKAALDYLQQNEVHILVSDWRMPEMSGIELCQIVK
NNHLPPFVILLTANNQTADIVLGIEAGADDFICKPFLPELLKVRMLAAMRIVQLQHNLSRNIQLLQQGLAKESALLSTIK
QDLFSAAKVQRELLPRSKTLPRDWQLHHEFQPASYLAGDLYQCFDLGDDQLGFYLIDAAGHGVAAALQSVSLAQRLSMER
TDWCGLSPQEIVNQVNRELSDPDNTGRFVTLLLGKINTLTGELRLCSAGHPAPLLLTETSCEPLPLDTELPLGIHGAVQY
QDQLVTLLPGSRLLLFSDGTYECQHPKFGFFGQARLQTLCSKANSLSDEALLHHLSHALQLWQGGTTQDDISMMLITYPS
ANYANAALEAL
>Mature_410_residues
PLSSLTSIQAVTLSVLVVEDTDCERFYITHLLRQFGWLVESRSNGKAALDYLQQNEVHILVSDWRMPEMSGIELCQIVKN
NHLPPFVILLTANNQTADIVLGIEAGADDFICKPFLPELLKVRMLAAMRIVQLQHNLSRNIQLLQQGLAKESALLSTIKQ
DLFSAAKVQRELLPRSKTLPRDWQLHHEFQPASYLAGDLYQCFDLGDDQLGFYLIDAAGHGVAAALQSVSLAQRLSMERT
DWCGLSPQEIVNQVNRELSDPDNTGRFVTLLLGKINTLTGELRLCSAGHPAPLLLTETSCEPLPLDTELPLGIHGAVQYQ
DQLVTLLPGSRLLLFSDGTYECQHPKFGFFGQARLQTLCSKANSLSDEALLHHLSHALQLWQGGTTQDDISMMLITYPSA
NYANAALEAL

Specific function: Member of the two-component regulatory system CseB/CseC involved in the stability of the cell envelope. CseB activates transcription of RNA polymerase sigma-E factor, in response to changes in the cell envelope [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=116, Percent_Identity=31.8965517241379, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790860, Length=119, Percent_Identity=32.7731092436975, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=34.1666666666667, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788191, Length=117, Percent_Identity=32.4786324786325, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082012, Length=143, Percent_Identity=26.5734265734266, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1788394, Length=130, Percent_Identity=29.2307692307692, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 45582; Mature: 45451

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLSSLTSIQAVTLSVLVVEDTDCERFYITHLLRQFGWLVESRSNGKAALDYLQQNEVHI
CCCCHHHHHEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEE
LVSDWRMPEMSGIELCQIVKNNHLPPFVILLTANNQTADIVLGIEAGADDFICKPFLPEL
EEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHH
LKVRMLAAMRIVQLQHNLSRNIQLLQQGLAKESALLSTIKQDLFSAAKVQRELLPRSKTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PRDWQLHHEFQPASYLAGDLYQCFDLGDDQLGFYLIDAAGHGVAAALQSVSLAQRLSMER
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
TDWCGLSPQEIVNQVNRELSDPDNTGRFVTLLLGKINTLTGELRLCSAGHPAPLLLTETS
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCEEEECCCCCCEEEEEECC
CEPLPLDTELPLGIHGAVQYQDQLVTLLPGSRLLLFSDGTYECQHPKFGFFGQARLQTLC
CCCCCCCCCCCCCCCCEEECCCEEEEECCCCEEEEEECCCCEECCCCCCCCHHHHHHHHH
SKANSLSDEALLHHLSHALQLWQGGTTQDDISMMLITYPSANYANAALEAL
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCC
>Mature Secondary Structure 
PLSSLTSIQAVTLSVLVVEDTDCERFYITHLLRQFGWLVESRSNGKAALDYLQQNEVHI
CCCHHHHHEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEE
LVSDWRMPEMSGIELCQIVKNNHLPPFVILLTANNQTADIVLGIEAGADDFICKPFLPEL
EEECCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHH
LKVRMLAAMRIVQLQHNLSRNIQLLQQGLAKESALLSTIKQDLFSAAKVQRELLPRSKTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PRDWQLHHEFQPASYLAGDLYQCFDLGDDQLGFYLIDAAGHGVAAALQSVSLAQRLSMER
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCC
TDWCGLSPQEIVNQVNRELSDPDNTGRFVTLLLGKINTLTGELRLCSAGHPAPLLLTETS
CCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCCCEEEECCCCCCEEEEEECC
CEPLPLDTELPLGIHGAVQYQDQLVTLLPGSRLLLFSDGTYECQHPKFGFFGQARLQTLC
CCCCCCCCCCCCCCCCEEECCCEEEEECCCCEEEEEECCCCEECCCCCCCCHHHHHHHHH
SKANSLSDEALLHHLSHALQLWQGGTTQDDISMMLITYPSANYANAALEAL
HHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]