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The map label for this gene is bepF [H]

Identifier: 117920437

GI number: 117920437

Start: 2371929

End: 2373185

Strand: Direct

Name: bepF [H]

Synonym: Shewana3_1992

Alternate gene names: 117920437

Gene position: 2371929-2373185 (Clockwise)

Preceding gene: 117920436

Following gene: 117920438

Centisome position: 47.7

GC content: 50.76

Gene sequence:

>1257_bases
ATGCCTCAACCATCTGTTACAGCTCGTTTTTTTGTTCCACGCTTAGGCTCATTTCCCCTTTATCTGAGTGGTGTTTTGCT
CTGTCTCTCGGTGAGTGGCTGCCAAGATCCTGAAATTAAAATCTCCCCCAAAATGTTGGTGGTGGAAAAAGTCACCACGG
CAACCGTACCACTCTATGGCAATTATATTGGCGTGACCCAAGCTTCCTTAGATGTGGAAGTTCGGGCGCGGGTCGATGGC
TTTGTGGAGGAGAAGCGTTTTGTCGAAGGTAGTGCTGTCAAAGCGGGTGAACTACTGTATCAGATTGATAATAAACCCTA
TGTGGCGGTGGTGAATCGTTTAAAGGCCAAACTGTCGTCACAGCAGGCGATTCTCGATAAGGCCGAGCGAGATGTGAAAC
GCTTAAAGCCGCTGTATGAGCAGGATGCAGCCAGTCAGCTCGATTACGATAATGCGCTCTCCACCTTGGCTCAGGCGCGT
TCTAACCTCACCGCGAGTCGCGCCGAGGTGGAAGAGGCCGAATTAGAACTCAGCTATACCGAAATTAAGGCGCCAATAGC
CGGACTGGTGAGTCGCTCCGAGGTCGATATTGGCGCTCTTGTGGGCAGTAAGGGCCAATCGCTACTGACCCGCGTTAAAC
AAGTCGATCCGATTTATGTCAGCTTTAATATGTCGGCACTGGATTATTTAAATGCCCAGCGCCGCCTGACCAGTTATTCG
GCGAAAAAAGAAGCCGAGGTCGAAGGTAAAGCATTGGCAGGCTTTGTGCGGATAACGCTTCCTGATAGCAGTGAATATCG
CTACCTCGGGGATGTGAGTTTTACCGATCCCCAGGTAAACCCTAACACTGGCACCTTTGAGGTGCGCGCCATTCTGCCTA
ATCCTGAAAAAGAGCTGTTGCCCGGCCAATATACTAATGTGCGGATTAAACTGTCCGAAATCCCCAATGCGATTGTTATC
CCGCAAAAAGCGACCCAAGTGGATCAGGGTGGGGTGTACGTGATGGTGGTATTGCCCAATAACACGGTCGAGCGACGTTT
TATCGTGATCGATCATCAAGGGATTGAAGGGGTTGTGGTTAAAAGTGGCCTCAAAGCTGGCGAGATGGTGATCACCGAAG
GCATGCACCGTGTACGCCACGGCCAGATTGCCGAGCCGTTAAGCGCGAAGGAATACGCTGAGAAGGAAGATGAGATGTCA
AAAGCCGAGGCACTTAAGCGCCAAGCCTTGGAGCAGCAAAAGCAGGAGCAAAAATAA

Upstream 100 bases:

>100_bases
TTGCATTGGTCACAGGACGTTACCTAGAACCGACTAAAATTGTTAAAACCACTTTGCCCATGCGAGTGGTTCCACTGTCT
TTAGAGTGCGGGATTCGCAT

Downstream 100 bases:

>100_bases
TGGCGCAGTTTTTTATTAATCGGCCGATTTTTGCCAGCGTCATCTCGATTGTTATCGTGCTGCTCGGGGTGATTGCGATG
TTTAAGCTGCCCGTCGATCA

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MPQPSVTARFFVPRLGSFPLYLSGVLLCLSVSGCQDPEIKISPKMLVVEKVTTATVPLYGNYIGVTQASLDVEVRARVDG
FVEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSSQQAILDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQAR
SNLTASRAEVEEAELELSYTEIKAPIAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYS
AKKEAEVEGKALAGFVRITLPDSSEYRYLGDVSFTDPQVNPNTGTFEVRAILPNPEKELLPGQYTNVRIKLSEIPNAIVI
PQKATQVDQGGVYVMVVLPNNTVERRFIVIDHQGIEGVVVKSGLKAGEMVITEGMHRVRHGQIAEPLSAKEYAEKEDEMS
KAEALKRQALEQQKQEQK

Sequences:

>Translated_418_residues
MPQPSVTARFFVPRLGSFPLYLSGVLLCLSVSGCQDPEIKISPKMLVVEKVTTATVPLYGNYIGVTQASLDVEVRARVDG
FVEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSSQQAILDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQAR
SNLTASRAEVEEAELELSYTEIKAPIAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYS
AKKEAEVEGKALAGFVRITLPDSSEYRYLGDVSFTDPQVNPNTGTFEVRAILPNPEKELLPGQYTNVRIKLSEIPNAIVI
PQKATQVDQGGVYVMVVLPNNTVERRFIVIDHQGIEGVVVKSGLKAGEMVITEGMHRVRHGQIAEPLSAKEYAEKEDEMS
KAEALKRQALEQQKQEQK
>Mature_417_residues
PQPSVTARFFVPRLGSFPLYLSGVLLCLSVSGCQDPEIKISPKMLVVEKVTTATVPLYGNYIGVTQASLDVEVRARVDGF
VEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSSQQAILDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARS
NLTASRAEVEEAELELSYTEIKAPIAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYSA
KKEAEVEGKALAGFVRITLPDSSEYRYLGDVSFTDPQVNPNTGTFEVRAILPNPEKELLPGQYTNVRIKLSEIPNAIVIP
QKATQVDQGGVYVMVVLPNNTVERRFIVIDHQGIEGVVVKSGLKAGEMVITEGMHRVRHGQIAEPLSAKEYAEKEDEMSK
AEALKRQALEQQKQEQK

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786668, Length=377, Percent_Identity=35.8090185676393, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1789929, Length=375, Percent_Identity=30.6666666666667, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789665, Length=379, Percent_Identity=33.245382585752, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87082036, Length=356, Percent_Identity=28.6516853932584, Blast_Score=150, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 46102; Mature: 45971

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00539 PYROKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQPSVTARFFVPRLGSFPLYLSGVLLCLSVSGCQDPEIKISPKMLVVEKVTTATVPLYG
CCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCEEEEEECCEEEEEEEC
NYIGVTQASLDVEVRARVDGFVEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSS
CEEEEEEEEEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
QQAILDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARSNLTASRAEVEEAELELSYT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEHH
EIKAPIAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYS
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHC
AKKEAEVEGKALAGFVRITLPDSSEYRYLGDVSFTDPQVNPNTGTFEVRAILPNPEKELL
CCCCCCCCCCEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHCC
PGQYTNVRIKLSEIPNAIVIPQKATQVDQGGVYVMVVLPNNTVERRFIVIDHQGIEGVVV
CCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEE
KSGLKAGEMVITEGMHRVRHGQIAEPLSAKEYAEKEDEMSKAEALKRQALEQQKQEQK
ECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQPSVTARFFVPRLGSFPLYLSGVLLCLSVSGCQDPEIKISPKMLVVEKVTTATVPLYG
CCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEECCCEEEEEECCEEEEEEEC
NYIGVTQASLDVEVRARVDGFVEEKRFVEGSAVKAGELLYQIDNKPYVAVVNRLKAKLSS
CEEEEEEEEEEEEEEEHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
QQAILDKAERDVKRLKPLYEQDAASQLDYDNALSTLAQARSNLTASRAEVEEAELELSYT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEHH
EIKAPIAGLVSRSEVDIGALVGSKGQSLLTRVKQVDPIYVSFNMSALDYLNAQRRLTSYS
HHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHC
AKKEAEVEGKALAGFVRITLPDSSEYRYLGDVSFTDPQVNPNTGTFEVRAILPNPEKELL
CCCCCCCCCCEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHCC
PGQYTNVRIKLSEIPNAIVIPQKATQVDQGGVYVMVVLPNNTVERRFIVIDHQGIEGVVV
CCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEEECCCCCEEEE
KSGLKAGEMVITEGMHRVRHGQIAEPLSAKEYAEKEDEMSKAEALKRQALEQQKQEQK
ECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]