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The map label for this gene is serC [H]

Identifier: 117920418

GI number: 117920418

Start: 2350697

End: 2351788

Strand: Direct

Name: serC [H]

Synonym: Shewana3_1973

Alternate gene names: 117920418

Gene position: 2350697-2351788 (Clockwise)

Preceding gene: 117920417

Following gene: 117920420

Centisome position: 47.28

GC content: 47.53

Gene sequence:

>1092_bases
GTGAGCGCGATTTATAATTTCTGTGCAGGTCCTGCGATGTTACCCGCAGCGGTAATGAAAAAAGCACAACAGGAATTACT
CGATTGGAATGGGCTAGGTGTCTCCGTGATGGAAGTCAGCCACAGAGGTAAGGAGTTTATCGCGCTGACCAAGCAAGCTG
AGGCGGATTTACGCGAGCTGATGCACATTCCACAGAACTATCATGTGTTGTTTATGCACGGCGGTGGTCGCGGTCAGTTC
TCTGCCGTTGTGAATAATTTTTTAGGCAACCAAGGCAGAGCCCTGTATTTAGTCAGTGGTCAATGGTCTTCTGCAGCATT
AGCCGAAGCACAAAAGCTGGCGGGTGACACTCAAATTGATAGCCTTAACATTGTTGAAAAACATAATGGACTCAATGCAG
TAGTGCTGCCTGAACTGCATAAGATTGATGCCGATTACCGTTATGTGCACTACTGCCCAAATGAGACAGTTGATGGTATC
GAAATTTTTGATGAGTTAGACAGTCCATGGCCGATTGTCGCCGACTTATCATCTACCATTATGTCTCGCGAAATCGATGT
CAGTCGTTACGGTTTAATCTATGCTGGCGCACAGAAGAACATTGGTCCTTCGGGCTTATCTATTGTGATCGTGCGTGATG
ATATGTTGAAGCTGCCGAGTTTAACCCAATCATCCATCATGGATTACCGTTTAGCCGTTGAGCATGACTCCATGTTCAAC
ACGCCGCCAACCTTTGCTTGGTACTTAGCGGCTGAAGTATTTGCTTGGCTCAAATCCTTAGGTGGTGTGGCTAGTATCGC
GAAAATCAATCAGCAAAAAGCGCAAATGCTGTATGCCTGTATCGATGCCAATCCTTTCTATAAAAATGGTGTCGTCGCGG
CAAACCGCTCACAAATGAACGTGACTTTCCAACTGGCGGATGAATCCCTTGATGGCGCCTTCTTAAAAGAGGCCGAAGCG
GCGGGCCTAGTGGCCTTAAAAGGTCATCGAATCGTTGGTGGCATGCGTGCCAGCCTTTACAATGCGATGCCACTTGAAGG
TGTCGCCGCGCTGGTGAGCTTTATGAACGAATTTGCGGCAAAGCATAGCTAA

Upstream 100 bases:

>100_bases
GAGTATGAAAACGAGCGTCCAATTGGACGCTCGTTTTTTTCATGGCAACGTTTTATTTTATGAATTCTAATATCATGGTT
TGTAAATAAGGAGAGTGGCA

Downstream 100 bases:

>100_bases
GCCAAGTAATGAAGTTTACCTAACTTGCTTAACTCGCTGATTGATACGTGTCGTTTAAAGTCAGTTTTAACAGCGTAAAG
TGAGAAAAAAAACGAATGCC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLRELMHIPQNYHVLFMHGGGRGQF
SAVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDTQIDSLNIVEKHNGLNAVVLPELHKIDADYRYVHYCPNETVDGI
EIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFN
TPPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMNVTFQLADESLDGAFLKEAEA
AGLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAAKHS

Sequences:

>Translated_363_residues
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLRELMHIPQNYHVLFMHGGGRGQF
SAVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDTQIDSLNIVEKHNGLNAVVLPELHKIDADYRYVHYCPNETVDGI
EIFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFN
TPPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMNVTFQLADESLDGAFLKEAEA
AGLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAAKHS
>Mature_362_residues
SAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLRELMHIPQNYHVLFMHGGGRGQFS
AVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDTQIDSLNIVEKHNGLNAVVLPELHKIDADYRYVHYCPNETVDGIE
IFDELDSPWPIVADLSSTIMSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFNT
PPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMNVTFQLADESLDGAFLKEAEAA
GLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAAKHS

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=369, Percent_Identity=41.7344173441734, Blast_Score=288, Evalue=4e-78,
Organism=Homo sapiens, GI10863955, Length=365, Percent_Identity=37.5342465753425, Blast_Score=241, Evalue=1e-63,
Organism=Escherichia coli, GI1787136, Length=364, Percent_Identity=59.0659340659341, Blast_Score=433, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17506897, Length=365, Percent_Identity=42.1917808219178, Blast_Score=280, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6324758, Length=388, Percent_Identity=39.1752577319588, Blast_Score=249, Evalue=3e-67,
Organism=Drosophila melanogaster, GI21356589, Length=364, Percent_Identity=43.956043956044, Blast_Score=305, Evalue=4e-83,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39649; Mature: 39518

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLREL
CCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCEEEEEHHHHHHHHHHH
MHIPQNYHVLFMHGGGRGQFSAVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDTQID
HHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
SLNIVEKHNGLNAVVLPELHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTI
CEEEEECCCCCCEEECCHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHH
MSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFN
HHHCCCHHHCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHEEEEEECCCCCC
TPPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMN
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCEE
VTFQLADESLDGAFLKEAEAAGLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAA
EEEEECCCCCCCHHHHHHCCCCEEEEECCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHH
KHS
CCC
>Mature Secondary Structure 
SAIYNFCAGPAMLPAAVMKKAQQELLDWNGLGVSVMEVSHRGKEFIALTKQAEADLREL
CCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCEEEEEHHHHHHHHHHH
MHIPQNYHVLFMHGGGRGQFSAVVNNFLGNQGRALYLVSGQWSSAALAEAQKLAGDTQID
HHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
SLNIVEKHNGLNAVVLPELHKIDADYRYVHYCPNETVDGIEIFDELDSPWPIVADLSSTI
CEEEEECCCCCCEEECCHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCCCCHHHHHHHH
MSREIDVSRYGLIYAGAQKNIGPSGLSIVIVRDDMLKLPSLTQSSIMDYRLAVEHDSMFN
HHHCCCHHHCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHEEEEEECCCCCC
TPPTFAWYLAAEVFAWLKSLGGVASIAKINQQKAQMLYACIDANPFYKNGVVAANRSQMN
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCEEEECCCCEE
VTFQLADESLDGAFLKEAEAAGLVALKGHRIVGGMRASLYNAMPLEGVAALVSFMNEFAA
EEEEECCCCCCCHHHHHHCCCCEEEEECCEEECHHHHHHHCCCCHHHHHHHHHHHHHHHH
KHS
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]