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The map label for this gene is can [H]

Identifier: 117920354

GI number: 117920354

Start: 2266263

End: 2266868

Strand: Reverse

Name: can [H]

Synonym: Shewana3_1909

Alternate gene names: 117920354

Gene position: 2266868-2266263 (Counterclockwise)

Preceding gene: 117920355

Following gene: 117920353

Centisome position: 45.59

GC content: 50.5

Gene sequence:

>606_bases
ATGAAACTACTCAAACCCTTATTCGATAACAACCGTCGCTGGGCCGGACGCATTCGCCAAGAGCACCCTGATTTTTTTGA
ACAACTGGCGAAACAGCAGAACCCTGAATATCTTTGGATTGGTTGTTCCGACAGCCGAGTACCTTCAAACCAAATCATCG
ATTTAATGCCGGGCGAAGTCTTCGTTCACCGCAATATTGCCAACATGGTGATCCACACCGATCTTAACTGCCTGTCAGTA
CTGCAATACGCCATTGATGTGCTTAAGGTGAAGCACATTATGGTGGTTGGCCACTACGGCTGTGGCGGTGTACGTGCGGC
GATGGGCAGCCAGCGCTTAGGCCTTATCGACAACTGGCTCGGCCATTTACGCGATATTTACCGCATCTACCACGATGAAT
TAATGCAAATGGATGAAGCCAAGCGTTTCGACCGCCTGTGTGAACTCAACGTAATTGAGCAAGTGGCCAACGTCACCAGC
ACCACCATCGTGCAGGAAGCGTGGGCTCGCGGCCAAGAACTGGCGATCCACGGCTGGATTTACGGTATTGATAATGGTCT
GTTAACCGACCTTGATGTGACCGTCGATCGCGCGCAAAAGATTTAA

Upstream 100 bases:

>100_bases
CAAGCGTAAATTTACTGGTATACTCTTGCTAAAAATGTGCTGCTTGCATCACTTAGGGCAATAAAGACATTTTAATATGT
CAATAAAACAATAGGTTAAA

Downstream 100 bases:

>100_bases
ATCGATTTAGGAAACGCGCCATAAGCGCGACGTTTTCTCCGCCAAAAACCTGCCCAGTGCAGGTTTTTTATTTTGATGCA
TAGCAACATCTATCGCACGC

Product: carbonic anhydrase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MKLLKPLFDNNRRWAGRIRQEHPDFFEQLAKQQNPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAIDVLKVKHIMVVGHYGCGGVRAAMGSQRLGLIDNWLGHLRDIYRIYHDELMQMDEAKRFDRLCELNVIEQVANVTS
TTIVQEAWARGQELAIHGWIYGIDNGLLTDLDVTVDRAQKI

Sequences:

>Translated_201_residues
MKLLKPLFDNNRRWAGRIRQEHPDFFEQLAKQQNPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAIDVLKVKHIMVVGHYGCGGVRAAMGSQRLGLIDNWLGHLRDIYRIYHDELMQMDEAKRFDRLCELNVIEQVANVTS
TTIVQEAWARGQELAIHGWIYGIDNGLLTDLDVTVDRAQKI
>Mature_201_residues
MKLLKPLFDNNRRWAGRIRQEHPDFFEQLAKQQNPEYLWIGCSDSRVPSNQIIDLMPGEVFVHRNIANMVIHTDLNCLSV
LQYAIDVLKVKHIMVVGHYGCGGVRAAMGSQRLGLIDNWLGHLRDIYRIYHDELMQMDEAKRFDRLCELNVIEQVANVTS
TTIVQEAWARGQELAIHGWIYGIDNGLLTDLDVTVDRAQKI

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=201, Percent_Identity=57.2139303482587, Blast_Score=251, Evalue=2e-68,
Organism=Escherichia coli, GI1786534, Length=174, Percent_Identity=32.183908045977, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324292, Length=194, Percent_Identity=33.5051546391753, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23139; Mature: 23139

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKPLFDNNRRWAGRIRQEHPDFFEQLAKQQNPEYLWIGCSDSRVPSNQIIDLMPGEV
CCCCHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCE
FVHRNIANMVIHTDLNCLSVLQYAIDVLKVKHIMVVGHYGCGGVRAAMGSQRLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCCCHHHHHH
GHLRDIYRIYHDELMQMDEAKRFDRLCELNVIEQVANVTSTTIVQEAWARGQELAIHGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
YGIDNGLLTDLDVTVDRAQKI
EECCCCCEEHHHHHHHHHHCC
>Mature Secondary Structure
MKLLKPLFDNNRRWAGRIRQEHPDFFEQLAKQQNPEYLWIGCSDSRVPSNQIIDLMPGEV
CCCCHHHHCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEECCCCCE
FVHRNIANMVIHTDLNCLSVLQYAIDVLKVKHIMVVGHYGCGGVRAAMGSQRLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCCCCHHHHHH
GHLRDIYRIYHDELMQMDEAKRFDRLCELNVIEQVANVTSTTIVQEAWARGQELAIHGWI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
YGIDNGLLTDLDVTVDRAQKI
EECCCCCEEHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]