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The map label for this gene is msbB [H]

Identifier: 117920311

GI number: 117920311

Start: 2211053

End: 2211991

Strand: Direct

Name: msbB [H]

Synonym: Shewana3_1866

Alternate gene names: 117920311

Gene position: 2211053-2211991 (Clockwise)

Preceding gene: 117920310

Following gene: 117920319

Centisome position: 44.47

GC content: 49.52

Gene sequence:

>939_bases
TTGTCAAGACAGCCCAAACATTTTGACCGACGTTTTCAACTGGCCTTATTGCACCCTAAATATTGGGTCACTTGGTTGGC
GATCGGCCTATTAGTGATTTTTGGGATCATGCCCGCGTGGCTGCGTGATCCTATCGCCAGAACCTTGGCCAAACTGGTGG
CGCCTATTGCGAAAAAACCGATAGGCATTGCCAGAGCGAACTTAAAGGCGTGTTTCCCTGAAAAATCCGCCGCCGAAATT
GAAACTTTAATCGATGAGAACGTGCAGAACTTCGTATTAGTGCTGTTATCTCAAGGTGAGCTGTTAGTACGCTCCAAGGC
GCATTTACGCCGCCGTGTGAATCTCATGGGCTTTGAGCACGTACAAGCGGCGCAGGCGGAAGGGCAGCCTGTAATATTTA
TCATGCCCCATGTGTGGCCCATCGATTATGCGGGACTGAGGTTAAACCTCGACTTGCCCATGGTGACCATGGCTAAGGCC
CACAAAAACGCTCTATTTAACTGGTTTAATAATCGGGTACGTAGCAGTGGCGGTGGCCATGTTTATATGCGAGAGGCGGG
GATCCGCGCCTTGTTGGCCGAATTGAAGCAGAACAATAGCTTTTTCTATTTGCCCGATGAGGATTTAGGCCCAGATCAAA
GCGTGTTTACCCCGTTTTTAGGCACAGTTAAAGCAACATTACCCGTGGTTGGCCGCTTAGCTCAGGCGGGAAATGCCCAA
GTGCTGCCGGTGAAAATTGGTTATAACCAAGCTTCACGCCAGTTTGATTTAACCGTAATGCCCGCGATTGCCGCCGAAGA
CATGGTCGGTAAAGAAAACGAAGCGTTGGCACTGAATAAAGCGGTTGAGCAAGTGATCCTCGCTTACCCTGAGCAGTATA
TGTGGTTCTTAAGATTGCTTAAGACCCGCCCTGAAGGGCAAGCCTCGATTTATCAATAG

Upstream 100 bases:

>100_bases
GTAATTTCTTAAAGTTTGATAGGAAAGCCACTCCATCGCGAGTGGCTTTCCTATTTTCTTCCTATGCGAATTCAGTCTTT
AACTGTCTGAGGTGATTCCT

Downstream 100 bases:

>100_bases
TTATTTATCTATAGCGACTTATCGATAGTGAAAGTGGCTGCTAGCAGACCAATAAAATGGGCTTTAAGTGGATACTTAAA
GCCCATTTTATATCAAGTGT

Product: lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSRQPKHFDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIARTLAKLVAPIAKKPIGIARANLKACFPEKSAAEI
ETLIDENVQNFVLVLLSQGELLVRSKAHLRRRVNLMGFEHVQAAQAEGQPVIFIMPHVWPIDYAGLRLNLDLPMVTMAKA
HKNALFNWFNNRVRSSGGGHVYMREAGIRALLAELKQNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQ
VLPVKIGYNQASRQFDLTVMPAIAAEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLLKTRPEGQASIYQ

Sequences:

>Translated_312_residues
MSRQPKHFDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIARTLAKLVAPIAKKPIGIARANLKACFPEKSAAEI
ETLIDENVQNFVLVLLSQGELLVRSKAHLRRRVNLMGFEHVQAAQAEGQPVIFIMPHVWPIDYAGLRLNLDLPMVTMAKA
HKNALFNWFNNRVRSSGGGHVYMREAGIRALLAELKQNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQ
VLPVKIGYNQASRQFDLTVMPAIAAEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLLKTRPEGQASIYQ
>Mature_311_residues
SRQPKHFDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIARTLAKLVAPIAKKPIGIARANLKACFPEKSAAEIE
TLIDENVQNFVLVLLSQGELLVRSKAHLRRRVNLMGFEHVQAAQAEGQPVIFIMPHVWPIDYAGLRLNLDLPMVTMAKAH
KNALFNWFNNRVRSSGGGHVYMREAGIRALLAELKQNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQV
LPVKIGYNQASRQFDLTVMPAIAAEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLLKTRPEGQASIYQ

Specific function: Transfers myristate or laurate, activated on ACP, to (KDO)2-(lauroyl)-lipid IVA [H]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the htrB/msbB family [H]

Homologues:

Organism=Escherichia coli, GI1788161, Length=309, Percent_Identity=32.6860841423948, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI87082094, Length=303, Percent_Identity=29.042904290429, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787292, Length=304, Percent_Identity=28.6184210526316, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004960
- InterPro:   IPR011921 [H]

Pfam domain/function: PF03279 Lip_A_acyltrans [H]

EC number: 2.3.1.-

Molecular weight: Translated: 35077; Mature: 34945

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQPKHFDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIARTLAKLVAPIAKKP
CCCCCCCHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGIARANLKACFPEKSAAEIETLIDENVQNFVLVLLSQGELLVRSKAHLRRRVNLMGFEH
CCHHHCCHHHCCCCCHHHHHHHHHHCCHHHEEEEEECCCCEEEHHHHHHHHHHHHCCHHH
VQAAQAEGQPVIFIMPHVWPIDYAGLRLNLDLPMVTMAKAHKNALFNWFNNRVRSSGGGH
HHHHHCCCCEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
VYMREAGIRALLAELKQNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQ
EEEEHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLPVKIGYNQASRQFDLTVMPAIAAEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLL
EEEEEECCCCCCCEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KTRPEGQASIYQ
HCCCCCCCCCCC
>Mature Secondary Structure 
SRQPKHFDRRFQLALLHPKYWVTWLAIGLLVIFGIMPAWLRDPIARTLAKLVAPIAKKP
CCCCCCHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
IGIARANLKACFPEKSAAEIETLIDENVQNFVLVLLSQGELLVRSKAHLRRRVNLMGFEH
CCHHHCCHHHCCCCCHHHHHHHHHHCCHHHEEEEEECCCCEEEHHHHHHHHHHHHCCHHH
VQAAQAEGQPVIFIMPHVWPIDYAGLRLNLDLPMVTMAKAHKNALFNWFNNRVRSSGGGH
HHHHHCCCCEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCE
VYMREAGIRALLAELKQNNSFFYLPDEDLGPDQSVFTPFLGTVKATLPVVGRLAQAGNAQ
EEEEHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCE
VLPVKIGYNQASRQFDLTVMPAIAAEDMVGKENEALALNKAVEQVILAYPEQYMWFLRLL
EEEEEECCCCCCCEEEEEEECHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KTRPEGQASIYQ
HCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]