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The map label for this gene is yeiG [H]

Identifier: 117920285

GI number: 117920285

Start: 2179947

End: 2180786

Strand: Direct

Name: yeiG [H]

Synonym: Shewana3_1838

Alternate gene names: 117920285

Gene position: 2179947-2180786 (Clockwise)

Preceding gene: 117920284

Following gene: 117920286

Centisome position: 43.84

GC content: 49.52

Gene sequence:

>840_bases
ATGACCATAGAAAATATCAGCTGTAACAAGAGCTTTGGTGGTTGGCACAAACAGTATCGCCATCAATCTCAGGCGCTGAA
TTGCGAGATGCGCTTTGCGATTTACCTGCCTCCGGAGGCGGCCAACAAACCTGTGCCTGTGTTGTATTGGCTATCGGGTC
TCACCTGTACCGACGAAAACTTTATGCAGAAGGCGGGCGCGCAGCGTATTGCGGCTCAATTGGGGATAGCCATCGTTGCC
CCCGATACCAGCCCGCGTGGTGATGATGTTGCCGATGCACCGGATAAAGCCTATGACTTAGGCTTAGGCGCGGGGTTTTA
TTTGAACGCGACCAGAGCGCCTTGGAATCGTCACTATAAAATGTACGACTATATAGTGCATGAATTGCCTGCGCTGATCG
AAGCCAATTTCCCCGTGACAGATCAACGCGCTATCTCTGGCCATTCGATGGGCGGGCATGGCGCGTTAGTGATAGGGTTA
ACCAATCCCCACAGATACAGTTCAATCTCGGCCTTTAGTCCTATCAGTAATCCAAGCAACGCGCCTTGGGGGATTAAAGC
TTTTACCGAGTATTTGGGCGAGAATCGCGAGCACTGGCGCCAATACGATGCCTGTGAGTTACTCAAATTGGCGATTAACG
AAGTGCCCGTATTAGTCGACCAAGGTGACGCCGACAGCTTTTTAGAGGCGCAACTGATGCCGCAAACGCTCAGTGATATT
GCCAAAGCAAAAGGTTACCCCTTAGATTTGCGTATGCAGGCGGGATACGACCATAGCTATTATTTTATTGCGAGCTTTAT
CGAAGAGCACCTTAAATTCCATAGCTTGTATTTTAAATAA

Upstream 100 bases:

>100_bases
ATAACCGCTAACGGCTTATCTGCTGCTTATGCGTTTTAAGCTTGTGATAGGGCCTTGAACGGCAAGCTAAACGCTAAAAG
TGAACAGGAAAGGGATTGAC

Downstream 100 bases:

>100_bases
GGCTGCCTAGCGTTAACCCCCAAGCATTAAACCCTAGAGTTAAACTTTAGGGTTTAATATAAAAAGCGCAGTGAACATTA
AGTTCACCGCGCTTTTTATT

Product: putative esterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAANKPVPVLYWLSGLTCTDENFMQKAGAQRIAAQLGIAIVA
PDTSPRGDDVADAPDKAYDLGLGAGFYLNATRAPWNRHYKMYDYIVHELPALIEANFPVTDQRAISGHSMGGHGALVIGL
TNPHRYSSISAFSPISNPSNAPWGIKAFTEYLGENREHWRQYDACELLKLAINEVPVLVDQGDADSFLEAQLMPQTLSDI
AKAKGYPLDLRMQAGYDHSYYFIASFIEEHLKFHSLYFK

Sequences:

>Translated_279_residues
MTIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAANKPVPVLYWLSGLTCTDENFMQKAGAQRIAAQLGIAIVA
PDTSPRGDDVADAPDKAYDLGLGAGFYLNATRAPWNRHYKMYDYIVHELPALIEANFPVTDQRAISGHSMGGHGALVIGL
TNPHRYSSISAFSPISNPSNAPWGIKAFTEYLGENREHWRQYDACELLKLAINEVPVLVDQGDADSFLEAQLMPQTLSDI
AKAKGYPLDLRMQAGYDHSYYFIASFIEEHLKFHSLYFK
>Mature_278_residues
TIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAANKPVPVLYWLSGLTCTDENFMQKAGAQRIAAQLGIAIVAP
DTSPRGDDVADAPDKAYDLGLGAGFYLNATRAPWNRHYKMYDYIVHELPALIEANFPVTDQRAISGHSMGGHGALVIGLT
NPHRYSSISAFSPISNPSNAPWGIKAFTEYLGENREHWRQYDACELLKLAINEVPVLVDQGDADSFLEAQLMPQTLSDIA
KAKGYPLDLRMQAGYDHSYYFIASFIEEHLKFHSLYFK

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=281, Percent_Identity=50.5338078291815, Blast_Score=305, Evalue=2e-83,
Organism=Escherichia coli, GI1788477, Length=278, Percent_Identity=58.273381294964, Blast_Score=344, Evalue=3e-96,
Organism=Escherichia coli, GI1786551, Length=273, Percent_Identity=55.3113553113553, Blast_Score=317, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17510185, Length=279, Percent_Identity=49.1039426523297, Blast_Score=262, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6322393, Length=283, Percent_Identity=44.5229681978799, Blast_Score=236, Evalue=4e-63,
Organism=Drosophila melanogaster, GI45551932, Length=280, Percent_Identity=48.9285714285714, Blast_Score=278, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24648347, Length=280, Percent_Identity=48.9285714285714, Blast_Score=278, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 31252; Mature: 31120

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAANKPVPVLYWLSGLTCTDEN
CCCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEEEEECCCEECCHH
FMQKAGAQRIAAQLGIAIVAPDTSPRGDDVADAPDKAYDLGLGAGFYLNATRAPWNRHYK
HHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCHHCCCCCCCEEEECCCCCHHHHHH
MYDYIVHELPALIEANFPVTDQRAISGHSMGGHGALVIGLTNPHRYSSISAFSPISNPSN
HHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
APWGIKAFTEYLGENREHWRQYDACELLKLAINEVPVLVDQGDADSFLEAQLMPQTLSDI
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHCHHHHHHH
AKAKGYPLDLRMQAGYDHSYYFIASFIEEHLKFHSLYFK
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIENISCNKSFGGWHKQYRHQSQALNCEMRFAIYLPPEAANKPVPVLYWLSGLTCTDEN
CCCCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCCEEEEEECCCEECCHH
FMQKAGAQRIAAQLGIAIVAPDTSPRGDDVADAPDKAYDLGLGAGFYLNATRAPWNRHYK
HHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCCCHHCCCCCCCEEEECCCCCHHHHHH
MYDYIVHELPALIEANFPVTDQRAISGHSMGGHGALVIGLTNPHRYSSISAFSPISNPSN
HHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
APWGIKAFTEYLGENREHWRQYDACELLKLAINEVPVLVDQGDADSFLEAQLMPQTLSDI
CCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHCHHHHHHH
AKAKGYPLDLRMQAGYDHSYYFIASFIEEHLKFHSLYFK
HHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA