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The map label for this gene is hlyB [H]

Identifier: 117920237

GI number: 117920237

Start: 2116330

End: 2118324

Strand: Direct

Name: hlyB [H]

Synonym: Shewana3_1790

Alternate gene names: 117920237

Gene position: 2116330-2118324 (Clockwise)

Preceding gene: 117920236

Following gene: 117920238

Centisome position: 42.56

GC content: 48.07

Gene sequence:

>1995_bases
ATGAAATGGCAATGGATTGGCAACCTCAGCTTAAAGCAAAAATTACTTATGGTTGTATTGCCACCGTTATTTGCGTGTTT
TCTGTATGGTGCGTTGTTTCTCATTGAAAAATATGAATATCGTCAAGAGCTCAAGCTGATTGTGCAATTGAGTGAACTGG
CCGTCACCAACAGTAACTTGGTGCATGAATTACAAAAAGAGCGCGGCATGAGCGCTGGCTTTATTGGCTCAGCCGGTAAA
GCCTTTGCAGGCAAAATTCCTGGTCAAAGACAGTTGACCGACACTCAGTTGAGACAATTCCAGGATTTCATTGCAAACAA
TGCGTTACCCGAAGTATTTGCGCCTAAGTTGCGGGAGATAAACACCCAACTTGGCCGCCTTTCTAGCATACGTTCTCAGG
TCGATAGCCTATCCATTAGTGTGGCCGATGAAGTGGCCTATTACACCGACTTAAACAAACAGCTATTAGCCATCGTCGAT
GAAACGGCAAAGGCGGGGGCTAACCAAGAAATTGCCATTAAGGCTGCAGCATTCAGTGCCTATCTACAGATGAAGGAGAG
GGCGGGGATTGAGCGGGCGGTACTGAGTTCAACCTTCGGACAAGCAGGCTTTAAGCCTAAGGTTTATGCCAAGTTTATTA
CCTTAGTCTCTGAGCAAAATACGTATCTTGAGCGCTTCTTGGCGCTGGCCACGCCCAATTTGGTGGATGGTATTCGCCAG
CTGCAAAATGGTAACGAAGTTAAAGAGGTTGAGGCATTAAGACAAATAGCAACCGATCAAGATAATCAGAAAATTCAACA
ACAAAACCCAGAGGATTGGTTTGCTAAATCCACGGCGCGTATCGACCGTTTGCGTGACTTTGAGCAACAAGTTTCTGCTG
ATCTGTTAAAAACCACCACAGACCGACTCTTTACTGCCAACAAGCATATGTTCTTCGTGCTGGTGACCTTAACTGTGGTG
CTAGTCTTAGTGTTATTGCTGAGTTTGTCGGTGATCCGTTATCTACACGACAGTGTGCATCATGTGTATTCGACGGTGAC
CAAGGCAAGAAAACATTATGATCTTAGTGTGCGCTTAACCCAAAACAGCTCGGATGAATTTGGGGAATTAGCCATTGCAT
TCAACGATATGATGAATGATTTCGAGAGTGTTATCCTGCAAGTGCGTGCTAGCGCTAGCAAGTTACAGCAAGCGGTAGAG
CAAATGGATGTGTGCACCCACGCAATGGAGCAAGATGTGATGGCAGGGCACAGTGAGGCTGAGCAAGTGGCCTCGGCAAT
GACAGAGATGAGCGCAACCGTGGCAGAAATCGCCAGTAACGCCGTTAATGCCTCGGAAGCTTCCACCGCGGCGAACCATG
AAGCGAAAGCGGGTAATATCGAAGTGGGCCGCACCAGTGCCGCCATTAAGGCTTTAGCCAATGATATTGATGGCGCCTCT
AAAGCCATTAATGAACTCGACCGTGAAATCCACGGTATTGTGGTGGTGCTCGATGTGATCAGCGGCATCGCCGAACAAAC
GAATCTACTCGCGCTTAATGCGGCAATTGAAGCGGCAAGGGCTGGCGAAATGGGACGAGGCTTTGCTGTAGTGGCCGATG
AGGTGCGAAGCCTCGCGCAGCGCTCACAAACCTCGACCTCGGATATTAAGAACATGACGGATAGACTCAAATCGGGTGCC
AGCATCGCCGTTAAAGCGATGGAGCGCGGGCTGATGCAGGCCAATAACAGCGTGCACGAAGCCGAGCAGGCGGGGATTGA
GCTTAAACGCATCGTAGAGCAAGTGGATATTATCGACCGCATGAATGAACAAATTGCCACGGCAACCCATGAGCAGTCTG
CCGTGTCAGAGGATGTGAATCGCAATGCATTAAAAATCAGTGAAATTTACCTCAATACCCAGAGGATTTCGGATGAATTA
CGGGAATTGACCAAAGCACTGACCTACGATGCGGCCTTAATGTCTAAGGAAGTGAACAAGTTCCACGTCAATTAA

Upstream 100 bases:

>100_bases
TAGCAGTTGCTAAATTAGCGCAAAATGGTCGTTATCGTGTTAATCCTATGCTATACCTTATTTGTCTTACCTTTTAACCC
CATCTAATAAGGATATCGCT

Downstream 100 bases:

>100_bases
TGGTGAAAGCCGGACATAAATCCCACTTTATCAGGCGGTTTGTTTAGCAATTGCGCAACCGCCTGAAATCCTCTCTTTTT
TACTTGACCACCCACAGGCT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 664; Mature: 664

Protein sequence:

>664_residues
MKWQWIGNLSLKQKLLMVVLPPLFACFLYGALFLIEKYEYRQELKLIVQLSELAVTNSNLVHELQKERGMSAGFIGSAGK
AFAGKIPGQRQLTDTQLRQFQDFIANNALPEVFAPKLREINTQLGRLSSIRSQVDSLSISVADEVAYYTDLNKQLLAIVD
ETAKAGANQEIAIKAAAFSAYLQMKERAGIERAVLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVDGIRQ
LQNGNEVKEVEALRQIATDQDNQKIQQQNPEDWFAKSTARIDRLRDFEQQVSADLLKTTTDRLFTANKHMFFVLVTLTVV
LVLVLLLSLSVIRYLHDSVHHVYSTVTKARKHYDLSVRLTQNSSDEFGELAIAFNDMMNDFESVILQVRASASKLQQAVE
QMDVCTHAMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVNASEASTAANHEAKAGNIEVGRTSAAIKALANDIDGAS
KAINELDREIHGIVVVLDVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMTDRLKSGA
SIAVKAMERGLMQANNSVHEAEQAGIELKRIVEQVDIIDRMNEQIATATHEQSAVSEDVNRNALKISEIYLNTQRISDEL
RELTKALTYDAALMSKEVNKFHVN

Sequences:

>Translated_664_residues
MKWQWIGNLSLKQKLLMVVLPPLFACFLYGALFLIEKYEYRQELKLIVQLSELAVTNSNLVHELQKERGMSAGFIGSAGK
AFAGKIPGQRQLTDTQLRQFQDFIANNALPEVFAPKLREINTQLGRLSSIRSQVDSLSISVADEVAYYTDLNKQLLAIVD
ETAKAGANQEIAIKAAAFSAYLQMKERAGIERAVLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVDGIRQ
LQNGNEVKEVEALRQIATDQDNQKIQQQNPEDWFAKSTARIDRLRDFEQQVSADLLKTTTDRLFTANKHMFFVLVTLTVV
LVLVLLLSLSVIRYLHDSVHHVYSTVTKARKHYDLSVRLTQNSSDEFGELAIAFNDMMNDFESVILQVRASASKLQQAVE
QMDVCTHAMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVNASEASTAANHEAKAGNIEVGRTSAAIKALANDIDGAS
KAINELDREIHGIVVVLDVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMTDRLKSGA
SIAVKAMERGLMQANNSVHEAEQAGIELKRIVEQVDIIDRMNEQIATATHEQSAVSEDVNRNALKISEIYLNTQRISDEL
RELTKALTYDAALMSKEVNKFHVN
>Mature_664_residues
MKWQWIGNLSLKQKLLMVVLPPLFACFLYGALFLIEKYEYRQELKLIVQLSELAVTNSNLVHELQKERGMSAGFIGSAGK
AFAGKIPGQRQLTDTQLRQFQDFIANNALPEVFAPKLREINTQLGRLSSIRSQVDSLSISVADEVAYYTDLNKQLLAIVD
ETAKAGANQEIAIKAAAFSAYLQMKERAGIERAVLSSTFGQAGFKPKVYAKFITLVSEQNTYLERFLALATPNLVDGIRQ
LQNGNEVKEVEALRQIATDQDNQKIQQQNPEDWFAKSTARIDRLRDFEQQVSADLLKTTTDRLFTANKHMFFVLVTLTVV
LVLVLLLSLSVIRYLHDSVHHVYSTVTKARKHYDLSVRLTQNSSDEFGELAIAFNDMMNDFESVILQVRASASKLQQAVE
QMDVCTHAMEQDVMAGHSEAEQVASAMTEMSATVAEIASNAVNASEASTAANHEAKAGNIEVGRTSAAIKALANDIDGAS
KAINELDREIHGIVVVLDVISGIAEQTNLLALNAAIEAARAGEMGRGFAVVADEVRSLAQRSQTSTSDIKNMTDRLKSGA
SIAVKAMERGLMQANNSVHEAEQAGIELKRIVEQVDIIDRMNEQIATATHEQSAVSEDVNRNALKISEIYLNTQRISDEL
RELTKALTYDAALMSKEVNKFHVN

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=286, Percent_Identity=31.1188811188811, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI2367378, Length=361, Percent_Identity=27.4238227146814, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787690, Length=361, Percent_Identity=28.5318559556787, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1789453, Length=373, Percent_Identity=26.2734584450402, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1788194, Length=222, Percent_Identity=34.6846846846847, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73313; Mature: 73313

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS50885 HAMP ; PS50906 NIT ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCCC
>Mature Secondary Structure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HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]