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The map label for this gene is gltS [H]

Identifier: 117919989

GI number: 117919989

Start: 1798073

End: 1799296

Strand: Reverse

Name: gltS [H]

Synonym: Shewana3_1541

Alternate gene names: 117919989

Gene position: 1799296-1798073 (Counterclockwise)

Preceding gene: 117919990

Following gene: 117919985

Centisome position: 36.19

GC content: 49.35

Gene sequence:

>1224_bases
ATGCACACCACTTATACAATTGGCGAACTCGAGTCGTTCTTAATTGCTATCTTCGTGCTGTTTATTGGCCATTCCATCAA
TCGCCATGTGCGTGTTTTTAGACAATACAATATTCCCGAACCTATCGTTGGCGGGCTAGTCGTCGCCGCCGTCGTGGCCT
TTTTACATTTCCAAGACATCACCCTCGCCTTTAGTTTACCCATGCAAAATACCTTAATGCTGATGTTTTTCAGTACGATA
GGTTTATCTGCAAACTATAAGCTACTGCTCAGTGGCGGCAAAAAAGTGTTTATCTTTTTAGGCGTCGCTTCGGTCTATAT
CGTCATTCAAAATGCTGTTGGGGTGAGTCTTGCAAGCCTCCTCGGTTTAGACCCCATCTTAGGCCTTATCGCAGGCTCAA
TTACGCTGTCAGGCGGCCATGGGACTGGCGTTGCCTGGTCACAAACCTTTGCCGAAAACTACGGCATCAACACCTTAGAG
CTGGCCATGGCGGCGGCTACCTTTGGCTTAGTCATGGGCGGCATTATCGGCGGCCCCGTCGCGCAGCGATTAATTGGCAA
ACACAATCTGGTCTCAAGCTACGGCATGGGCCGTAAACACCACGCCACGCATCCTCAACTGGTCACCTACGATCAGCTCG
AAGAAGACCAAGTCACCGCTAAGACAATCATCGAAACCCTGTTTGTACTGCTTATCTGCGTTGCTGGGGCGAAATGGTTT
ACTGTGCTTGTCAGCGAATATCAGCTGAATTGGCTCAAGATGCCGGACTTTGTCTATGCCCTGTTTCTTGGGGTGATCAT
CGCCAACATCACCGAAGTGACCCGAGGTTATAAACCCCATACCGAGAGTATCGATGTAATAGGCACTGTGGCACTGTCGT
TATTTCTCTCTATGGCCTTGATGAACCTCAAATTGTGGGAAATTTTGGATCTGGCTATCCCACTACTGATTATCCTGCTA
GTGCAAACCGCAGTGCTGGCGGTATTCGCCTATTTTGTGACCTTTAAAATCATGGGCAGCAACTATGACGCAGCGGTGAT
CACCGGCGGTCACTGTGGCTTTGGTATGGGCGCCACTCCTACGGCGGTGATGAATATGGGCGCACTGGTGTCACGCACAG
GCCCCTCTCCTCAGGCCTTTATGGTGGTACCGATTGTCGGCGCCTTCTTTATCGATATAGTCAATTTAATTGTATTGCAG
GGCTACCTCAGCTTTTTGATGTAA

Upstream 100 bases:

>100_bases
GATAATGCTAAATAACGAGATGGGTCGCCCTCACTCAGCTTGAATACAGCCAGCTTGAGTACAGCGGTATTCCCACACAA
ACCATTTGTAAGGAACTATC

Downstream 100 bases:

>100_bases
GAGTGCAACGCTTTATCATTAAACAAAAATGGCGCCGATAAGGGCGCCATTTTTATATCTCGTGAAGAGTGAAATCAAAG
GACAAGTTAGAACGTGCGCA

Product: sodium/glutamate symporter

Products: Na (I) [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: Glutamate permease [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MHTTYTIGELESFLIAIFVLFIGHSINRHVRVFRQYNIPEPIVGGLVVAAVVAFLHFQDITLAFSLPMQNTLMLMFFSTI
GLSANYKLLLSGGKKVFIFLGVASVYIVIQNAVGVSLASLLGLDPILGLIAGSITLSGGHGTGVAWSQTFAENYGINTLE
LAMAAATFGLVMGGIIGGPVAQRLIGKHNLVSSYGMGRKHHATHPQLVTYDQLEEDQVTAKTIIETLFVLLICVAGAKWF
TVLVSEYQLNWLKMPDFVYALFLGVIIANITEVTRGYKPHTESIDVIGTVALSLFLSMALMNLKLWEILDLAIPLLIILL
VQTAVLAVFAYFVTFKIMGSNYDAAVITGGHCGFGMGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNLIVLQ
GYLSFLM

Sequences:

>Translated_407_residues
MHTTYTIGELESFLIAIFVLFIGHSINRHVRVFRQYNIPEPIVGGLVVAAVVAFLHFQDITLAFSLPMQNTLMLMFFSTI
GLSANYKLLLSGGKKVFIFLGVASVYIVIQNAVGVSLASLLGLDPILGLIAGSITLSGGHGTGVAWSQTFAENYGINTLE
LAMAAATFGLVMGGIIGGPVAQRLIGKHNLVSSYGMGRKHHATHPQLVTYDQLEEDQVTAKTIIETLFVLLICVAGAKWF
TVLVSEYQLNWLKMPDFVYALFLGVIIANITEVTRGYKPHTESIDVIGTVALSLFLSMALMNLKLWEILDLAIPLLIILL
VQTAVLAVFAYFVTFKIMGSNYDAAVITGGHCGFGMGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNLIVLQ
GYLSFLM
>Mature_407_residues
MHTTYTIGELESFLIAIFVLFIGHSINRHVRVFRQYNIPEPIVGGLVVAAVVAFLHFQDITLAFSLPMQNTLMLMFFSTI
GLSANYKLLLSGGKKVFIFLGVASVYIVIQNAVGVSLASLLGLDPILGLIAGSITLSGGHGTGVAWSQTFAENYGINTLE
LAMAAATFGLVMGGIIGGPVAQRLIGKHNLVSSYGMGRKHHATHPQLVTYDQLEEDQVTAKTIIETLFVLLICVAGAKWF
TVLVSEYQLNWLKMPDFVYALFLGVIIANITEVTRGYKPHTESIDVIGTVALSLFLSMALMNLKLWEILDLAIPLLIILL
VQTAVLAVFAYFVTFKIMGSNYDAAVITGGHCGFGMGATPTAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNLIVLQ
GYLSFLM

Specific function: Catalyzes the sodium-dependent uptake of extracellular glutamate [H]

COG id: COG0786

COG function: function code E; Na+/glutamate symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gltS symporter family [H]

Homologues:

Organism=Escherichia coli, GI1790085, Length=392, Percent_Identity=48.2142857142857, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004445 [H]

Pfam domain/function: PF03616 Glt_symporter [H]

EC number: NA

Molecular weight: Translated: 43931; Mature: 43931

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTTYTIGELESFLIAIFVLFIGHSINRHVRVFRQYNIPEPIVGGLVVAAVVAFLHFQDI
CCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
TLAFSLPMQNTLMLMFFSTIGLSANYKLLLSGGKKVFIFLGVASVYIVIQNAVGVSLASL
HEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LGLDPILGLIAGSITLSGGHGTGVAWSQTFAENYGINTLELAMAAATFGLVMGGIIGGPV
HCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHH
AQRLIGKHNLVSSYGMGRKHHATHPQLVTYDQLEEDQVTAKTIIETLFVLLICVAGAKWF
HHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
TVLVSEYQLNWLKMPDFVYALFLGVIIANITEVTRGYKPHTESIDVIGTVALSLFLSMAL
HHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
MNLKLWEILDLAIPLLIILLVQTAVLAVFAYFVTFKIMGSNYDAAVITGGHCGFGMGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCH
TAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNLIVLQGYLSFLM
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MHTTYTIGELESFLIAIFVLFIGHSINRHVRVFRQYNIPEPIVGGLVVAAVVAFLHFQDI
CCCEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
TLAFSLPMQNTLMLMFFSTIGLSANYKLLLSGGKKVFIFLGVASVYIVIQNAVGVSLASL
HEEEECCCHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEEHHHHHHHHHHHHHHHHHHHH
LGLDPILGLIAGSITLSGGHGTGVAWSQTFAENYGINTLELAMAAATFGLVMGGIIGGPV
HCHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHH
AQRLIGKHNLVSSYGMGRKHHATHPQLVTYDQLEEDQVTAKTIIETLFVLLICVAGAKWF
HHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHH
TVLVSEYQLNWLKMPDFVYALFLGVIIANITEVTRGYKPHTESIDVIGTVALSLFLSMAL
HHHHHHHHCCEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHH
MNLKLWEILDLAIPLLIILLVQTAVLAVFAYFVTFKIMGSNYDAAVITGGHCGFGMGATP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCH
TAVMNMGALVSRTGPSPQAFMVVPIVGAFFIDIVNLIVLQGYLSFLM
HHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-glutamate [Periplasm] = Na (I) [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]