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The map label for this gene is glsA [H]

Identifier: 117919633

GI number: 117919633

Start: 1390927

End: 1391841

Strand: Direct

Name: glsA [H]

Synonym: Shewana3_1184

Alternate gene names: 117919633

Gene position: 1390927-1391841 (Clockwise)

Preceding gene: 117919632

Following gene: 117919634

Centisome position: 27.97

GC content: 49.29

Gene sequence:

>915_bases
ATGCCAGAACAGGCGTTATTAGAGGAAGTGGTCGACAAAGTTCGACCCTTGCTCGGCCAAGGAAAGGTTGCTAATTACAT
CCCTGCGCTCGCCAATGTTGATGCTGGTAAATTGGGCATTGCCGTGACCACAATCGACGGTGAAACCATAGGCGCAGGCG
ATTACCTTGAGCCATTTTCAATTCAAAGTATTTCTAAAGTTTTCAGCTTAACCTTAGCGCTAACTTTATATGAAGAAACC
GAAATTTGGAGCCGCGTCGGCAAAGAACCCTCGGGACACTCCTTCAATTCATTAGTCCAAGTTGAACTCGAGCGGGGTAA
ACCTCGCAATCCCTTTATTAATGCTGGCGCATTAGTCATCGCTGACTTATTACAGAGCCGTTTAGGGGCACCTAAGCATC
GGATGTTGGAATTGGTCAGGGCGCTGAGCCAAAACGATAAAGTCTGTTTCGATAAGCAAGTCGCGGATTCTGAATATCAG
CACAGTGCACGTAATGCGGCCATCGCTTATCTGATGAAATCCTTCGGCAATTTTCAAGGCGATGTCGATACAGTGCTGCG
CACTTATTTTCATTATTGCGCCTTAAAAATGAATTGCGCCGACCTATCGCGGGCGATGCTGTATTTAGCCAATCGCGGTA
AAACCTTAGATGGCACTGAGCTTATTTCGCAGGTGCAGACTCGGCAGTTAAATGCCCTGTTAGCAACCTCAGGCTTGTAC
GACGGCGCCGGTGAGTTTGCCTATCGTGTTGGTATGCCGGGTAAAAGCGGTGTCGGTGGCGGCATTATTGCGGTGATCCC
TGGGGAACTCTCGGTCTGCGTTTGGTCACCCGAATTAGATAATCAAGGTAACTCCCTCGCGGGGACGGCGATGCTTGAGC
ATCTTAGCCAGCGCCTCGGACGTTCAATCTTCTGA

Upstream 100 bases:

>100_bases
AGTGCACCGAGGAAGATGTTGCTGCAGTGAAGGCATTCTGGGCGGGTCAAAAAGTGACTCAACTCGAAGTTAGCGATCTG
TACGATATCTGGTGGAGTTA

Downstream 100 bases:

>100_bases
TTTAACTCTTCTATTAGCACTGTTAGGCTAACTATTAGTGAAATTCACTAATCTGCTATCGGTGCTAATTTTTATAACTC
CATACTAATCATATTGTTAC

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MPEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEET
EIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQ
HSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLGRSIF

Sequences:

>Translated_304_residues
MPEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEET
EIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQ
HSARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLGRSIF
>Mature_303_residues
PEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFSIQSISKVFSLTLALTLYEETE
IWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVIADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQH
SARNAAIAYLMKSFGNFQGDVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLYD
GAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=280, Percent_Identity=35.3571428571429, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=32.6530612244898, Blast_Score=155, Evalue=3e-38,
Organism=Escherichia coli, GI1787804, Length=303, Percent_Identity=62.3762376237624, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI1786693, Length=303, Percent_Identity=34.983498349835, Blast_Score=173, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17507019, Length=296, Percent_Identity=35.8108108108108, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17532727, Length=297, Percent_Identity=32.3232323232323, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193204073, Length=310, Percent_Identity=32.9032258064516, Blast_Score=157, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI193204075, Length=312, Percent_Identity=32.6923076923077, Blast_Score=155, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=34.7368421052632, Blast_Score=168, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=34.7368421052632, Blast_Score=167, Evalue=6e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 32925; Mature: 32794

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCCEECCCCCCCCCH
IQSISKVFSLTLALTLYEETEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQG
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
DVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLY
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC
>Mature Secondary Structure 
PEQALLEEVVDKVRPLLGQGKVANYIPALANVDAGKLGIAVTTIDGETIGAGDYLEPFS
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCCEECCCCCCCCCH
IQSISKVFSLTLALTLYEETEIWSRVGKEPSGHSFNSLVQVELERGKPRNPFINAGALVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHH
ADLLQSRLGAPKHRMLELVRALSQNDKVCFDKQVADSEYQHSARNAAIAYLMKSFGNFQG
HHHHHHHHCCCHHHHHHHHHHHCCCCCEEECHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
DVDTVLRTYFHYCALKMNCADLSRAMLYLANRGKTLDGTELISQVQTRQLNALLATSGLY
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGELSVCVWSPELDNQGNSLAGTAMLEHLSQRLG
CCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA