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The map label for this gene is aaeR [H]

Identifier: 117919540

GI number: 117919540

Start: 1284289

End: 1285212

Strand: Direct

Name: aaeR [H]

Synonym: Shewana3_1091

Alternate gene names: 117919540

Gene position: 1284289-1285212 (Clockwise)

Preceding gene: 117919537

Following gene: 117919541

Centisome position: 25.83

GC content: 53.57

Gene sequence:

>924_bases
ATGGATAGACTCGAAGCGGCAAAGGTGTTTGTGACTATTGTCGAACGGGGGAGCATGATTGGCGCCGCCGAGGCGTTAGA
TATGTCGCGCTCCATGGTGACCCGTTACTTGGCCGAGATGGAAGAATGGTCGGGCGCCCGTTTATTGCACCGTTCGACAA
GACGTTTGAGCCTGACCGATGCGGGTGAACAGGTGCTCGATTATTGTCAGCGTTTGCTTGAGTTGGCGCAGGAAGTCCCT
GCGGTAAGTCATGCTCAGAGTGCCCAGCCCCGAGGGCTACTGCGGATCAGCTGCTCGCAATTTATGGCGCATTTACTCCT
CCCCAGCGTCGTGCGCCCTTATTTAGCACAATACCCGCAGGCGAGTGTGAACTTTCATGTGACGAGTCAAACCGTTGATT
TAGTGGCTGAACGAATCGATCTTGCCATTCGTATCACCAACGAACTCGACCCTACGCTTATCGCCAGACGTTTAGGCGAG
TGTGAGTCTGTGGTGTGCGCGGCACCGAGTTATCTTGCCAGCCATTCGGCCATCACGCATCCCGAGGATTTAACTCGGCA
TAACTGCCTAACCTATTCCTACTTTGGCGATGTGATGTGGCGATTCACTCAAACGCCTATCGCCGTGAAGGCAACGCCAA
CGCAGGAAGTCGGGCAGATATTCAATATTCCGGTGAAGGGCAACCTAAGTGCCAATGACTCTATGGTGGTGTTAAACGCC
ACTTTGGCGGGGGAGGGAATTGCCATGCAGCCCCTGTGGGCGGCTAAACCGCACCTCGATTCGGGGGCATTAGTGCCATT
GCTGCGGGAATTCAAACCTCAATCCCTAGGCGTGTACGGGGTTTATCAATCCCGCAAACATATGCAGCCCGCATTAAGGG
TGATGATGGATATGCTAGTGCAGCATTTTAATGGGGCAATTTAA

Upstream 100 bases:

>100_bases
GATAAACACGGAAAATTGCGCTTGTTTGTTGCATAATTCGGATGAATTGGTGTTGAAAGCCGAGAATCTAGTGCAAGCTA
ATCCACAAGGGAGAATAACC

Downstream 100 bases:

>100_bases
GGGCGTGATCTTGAATGCGCGACTTGCACTTGCGCTTGCATCTCTATGAGATAGCGGCGACTGGGTTGCGTTGTTCGTTC
GACTCTGTCACTCGGTTAAC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTDAGEQVLDYCQRLLELAQEVP
AVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGE
CESVVCAAPSYLASHSAITHPEDLTRHNCLTYSYFGDVMWRFTQTPIAVKATPTQEVGQIFNIPVKGNLSANDSMVVLNA
TLAGEGIAMQPLWAAKPHLDSGALVPLLREFKPQSLGVYGVYQSRKHMQPALRVMMDMLVQHFNGAI

Sequences:

>Translated_307_residues
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTDAGEQVLDYCQRLLELAQEVP
AVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGE
CESVVCAAPSYLASHSAITHPEDLTRHNCLTYSYFGDVMWRFTQTPIAVKATPTQEVGQIFNIPVKGNLSANDSMVVLNA
TLAGEGIAMQPLWAAKPHLDSGALVPLLREFKPQSLGVYGVYQSRKHMQPALRVMMDMLVQHFNGAI
>Mature_307_residues
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTDAGEQVLDYCQRLLELAQEVP
AVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGE
CESVVCAAPSYLASHSAITHPEDLTRHNCLTYSYFGDVMWRFTQTPIAVKATPTQEVGQIFNIPVKGNLSANDSMVVLNA
TLAGEGIAMQPLWAAKPHLDSGALVPLLREFKPQSLGVYGVYQSRKHMQPALRVMMDMLVQHFNGAI

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=303, Percent_Identity=33.3333333333333, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI87081978, Length=305, Percent_Identity=32.1311475409836, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789440, Length=298, Percent_Identity=28.8590604026846, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786401, Length=308, Percent_Identity=29.8701298701299, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787589, Length=314, Percent_Identity=25.796178343949, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787128, Length=291, Percent_Identity=25.085910652921, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=27.4247491638796, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789173, Length=264, Percent_Identity=26.1363636363636, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=175, Percent_Identity=29.7142857142857, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787601, Length=135, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI87082132, Length=299, Percent_Identity=22.4080267558528, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34030; Mature: 34030

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEEECCC
AGEQVLDYCQRLLELAQEVPAVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQ
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGECESVVCAAPSYLASHSAITH
CCEEEEEEHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHCCCCCC
PEDLTRHNCLTYSYFGDVMWRFTQTPIAVKATPTQEVGQIFNIPVKGNLSANDSMVVLNA
HHHHHHCCCEEHHHHHHHHHHHHCCCEEEEECCHHHHHHEECCCCCCCCCCCCCEEEEEE
TLAGEGIAMQPLWAAKPHLDSGALVPLLREFKPQSLGVYGVYQSRKHMQPALRVMMDMLV
EECCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QHFNGAI
HHHCCCC
>Mature Secondary Structure
MDRLEAAKVFVTIVERGSMIGAAEALDMSRSMVTRYLAEMEEWSGARLLHRSTRRLSLTD
CCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCEEECCC
AGEQVLDYCQRLLELAQEVPAVSHAQSAQPRGLLRISCSQFMAHLLLPSVVRPYLAQYPQ
HHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCC
ASVNFHVTSQTVDLVAERIDLAIRITNELDPTLIARRLGECESVVCAAPSYLASHSAITH
CCEEEEEEHHHHHHHHHHHHEEEEECCCCCHHHHHHHHCCHHHHHHCCCHHHHHCCCCCC
PEDLTRHNCLTYSYFGDVMWRFTQTPIAVKATPTQEVGQIFNIPVKGNLSANDSMVVLNA
HHHHHHCCCEEHHHHHHHHHHHHCCCEEEEECCHHHHHHEECCCCCCCCCCCCCEEEEEE
TLAGEGIAMQPLWAAKPHLDSGALVPLLREFKPQSLGVYGVYQSRKHMQPALRVMMDMLV
EECCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
QHFNGAI
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]