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The map label for this gene is deoD [H]

Identifier: 117919493

GI number: 117919493

Start: 1221592

End: 1222302

Strand: Direct

Name: deoD [H]

Synonym: Shewana3_1044

Alternate gene names: 117919493

Gene position: 1221592-1222302 (Clockwise)

Preceding gene: 117919492

Following gene: 117919495

Centisome position: 24.57

GC content: 45.29

Gene sequence:

>711_bases
ATGGCAACACCACACATTAATGCTGTAGAGGGCGCATTCGCTGAGACAGTTCTGTTTCCAGGCGATCCATTACGTGCAAA
ATATATTGCTGAAACATTCTTAGAAAATGTTGAGCAAGTGACTGACGTTCGAAACATGCTAGGTTTTACCGGTACTTACA
AAGGTAAACGTATTTCTGTTATGGGTTCAGGCATGGGTATTCCTTCATGCTCAATCTATGCAACTGAATTAATTAAAGAC
TACGGTGTTAAGAACCTGATCCGCGTGGGTACTTGTGGCGCGATCAGCACTGACGTTAAAGTGCGCGATGTGATCATCGG
CATGGGTGCTTGTACCGATTCTCAAGTTAACCGTTTACGTTTCAAAGGCCAAGATTTCGCTGCTATCGCGAACTACGAGC
TGATGAATGCCGTGATCGAATCTGCCAAAGTGAAAGGCACTAAGATCCGTGTTGGTAACGTTTTCTCTGCCGATCTGTTC
TACACTCCTGATCCACAAATGTTTGACGTGATGGAAAAAATGGGCGTGTTAGGCGTAGAGATGGAAGCCGCTGGTTTATA
TGGTGTTGCCCATGAATTCGGTGCTCGTGCACTGTGTGTGGTAACTGTATCTGACCATATCCGTACTGGCGAGAAAACCA
CTTCTGATGAGCGTCAAACCACGTTCAACGATATGATCGTGATGACATTAGACGCAGCAATTACGCTGTAA

Upstream 100 bases:

>100_bases
TTTATCTAAGTAAACGTGCAAGATCTCGATTTGGCGGCCAACATTGGGCCGCCAGTAAACAAAGACTTAAGTCTTAATAA
AATAAACAGGGGTTATTTCG

Downstream 100 bases:

>100_bases
TCTGTCGCTAATCTCGTTATAAAAAAAGGGTTCGCATTGCGAACCCTTTTTTATTGCCTCGTATCTTCAAGTTCAATCGG
CTTAGCTGTGTTGCTGGCTC

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP 2 [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIKD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIANYELMNAVIESAKVKGTKIRVGNVFSADLF
YTPDPQMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIVMTLDAAITL

Sequences:

>Translated_236_residues
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIKD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIANYELMNAVIESAKVKGTKIRVGNVFSADLF
YTPDPQMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIVMTLDAAITL
>Mature_235_residues
ATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISVMGSGMGIPSCSIYATELIKDY
GVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLRFKGQDFAAIANYELMNAVIESAKVKGTKIRVGNVFSADLFY
TPDPQMFDVMEKMGVLGVEMEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIVMTLDAAITL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=69.2307692307692, Blast_Score=347, Evalue=4e-97,
Organism=Escherichia coli, GI1790265, Length=199, Percent_Identity=30.1507537688442, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25589; Mature: 25458

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISV
CCCCCCCHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGSGMGIPSCSIYATELIKDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHEE
FKGQDFAAIANYELMNAVIESAKVKGTKIRVGNVFSADLFYTPDPQMFDVMEKMGVLGVE
ECCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIVMTLDAAITL
EECCCHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCHHHHHHHCEEEEEEEEEECC
>Mature Secondary Structure 
ATPHINAVEGAFAETVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGKRISV
CCCCCCHHHCHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
MGSGMGIPSCSIYATELIKDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQVNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHEE
FKGQDFAAIANYELMNAVIESAKVKGTKIRVGNVFSADLFYTPDPQMFDVMEKMGVLGVE
ECCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCEEEECEEECCCCHHHHHHHHCCCEEEE
MEAAGLYGVAHEFGARALCVVTVSDHIRTGEKTTSDERQTTFNDMIVMTLDAAITL
EECCCHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCHHHHHHHCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]