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The map label for this gene is fmt [H]

Identifier: 117918493

GI number: 117918493

Start: 41372

End: 42328

Strand: Reverse

Name: fmt [H]

Synonym: Shewana3_0034

Alternate gene names: 117918493

Gene position: 42328-41372 (Counterclockwise)

Preceding gene: 117918494

Following gene: 117918492

Centisome position: 0.85

GC content: 52.56

Gene sequence:

>957_bases
TTGAAACCACTCAATATCATCTTCGCCGGAACACCGGATTTTGCCGCTCGCCATTTACAGGCGCTGATTAACTCACATCA
CAATGTGATTGCCGTCTACACTCAGCCGGACAGACCCGCAGGGCGCGGTAAAAAACTCACCGCCAGCCCAGTTAAAGAAC
TCGCAGTCAGCCACGACATTCCGGTTTATCAGCCGGGTTCACTGCGTAAAGAACCCGCGCAGCAAGAACTTGCCGCCCTC
AATGCCGATATTATGGTGGTTGTCGCCTACGGCTTAATCCTACCTAAAGTAGTGCTCGACACGCCGCGTTTAGGCTGCAT
CAATGTTCACGGTTCTATTCTGCCACGCTGGCGCGGTGCGGCGCCGATTCAACGCGCGTTGTGGGCAGGCGATAAAGAAA
CCGGTGTGACTATCATGCAAATGGATGTCGGCCTAGATACCGGCGACATGCTACTGAAAACCTACTTGCCGATTGAAGAT
GATGATACTTCAGCCACCCTTTACGAGAAGTTAGCTCTGCAAGGGCCAGACGCGCTGCTGCAAGCACTCGAAGGTTTAGC
CAACGGCACCCTAACGGCCGAGAAACAAGATGAAGTCTTAGCGAACTACGCCGAAAAGCTCAGTAAAGAAGAAGCGAGAC
TCGATTGGCGCAAATCCGCGACCCAACTTTGGCAAGAAGTTCGCGCCTTCAATCCTTGGCCTGTGAGCTATTTTGAGCAC
CAAGGCAATACCATTAAGGTGTGGCAGACCCAAGTCAGCACCACCAGCAGCAATGCCGCACCCGGCACTATTATCAGCGC
CAGTAAAAAAGGCATTGAAGTCGCTACCGGCGATGGTGTGTTAACTCTGCTCAGCATGCAATTACCCGGTAAAAAACCAC
TCAGCGTGGCCGACATACTCAATGCCCGCGGCGATTGGTTTACCCCAAACACTCGTCTTAATAACGAGGCGCAATAA

Upstream 100 bases:

>100_bases
ATTATTTGTCGATTATCTGTCGCCATTGAAACGCCAACGGATCAAACAGAAACTTGAAAAAGCGGCCAGACAGGACGCCA
AATAAGCATTAGGATCAGAT

Downstream 100 bases:

>100_bases
TGATGAACTTGCGTGCACTGGCGGCCAAAGCCATCTTCGAAGTCTTAGAGAAAGGCGTATCACTTTCAGTTGCCCTGCCA
GAACAGCAAAAGCATCTTGC

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MKPLNIIFAGTPDFAARHLQALINSHHNVIAVYTQPDRPAGRGKKLTASPVKELAVSHDIPVYQPGSLRKEPAQQELAAL
NADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTIMQMDVGLDTGDMLLKTYLPIED
DDTSATLYEKLALQGPDALLQALEGLANGTLTAEKQDEVLANYAEKLSKEEARLDWRKSATQLWQEVRAFNPWPVSYFEH
QGNTIKVWQTQVSTTSSNAAPGTIISASKKGIEVATGDGVLTLLSMQLPGKKPLSVADILNARGDWFTPNTRLNNEAQ

Sequences:

>Translated_318_residues
MKPLNIIFAGTPDFAARHLQALINSHHNVIAVYTQPDRPAGRGKKLTASPVKELAVSHDIPVYQPGSLRKEPAQQELAAL
NADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTIMQMDVGLDTGDMLLKTYLPIED
DDTSATLYEKLALQGPDALLQALEGLANGTLTAEKQDEVLANYAEKLSKEEARLDWRKSATQLWQEVRAFNPWPVSYFEH
QGNTIKVWQTQVSTTSSNAAPGTIISASKKGIEVATGDGVLTLLSMQLPGKKPLSVADILNARGDWFTPNTRLNNEAQ
>Mature_318_residues
MKPLNIIFAGTPDFAARHLQALINSHHNVIAVYTQPDRPAGRGKKLTASPVKELAVSHDIPVYQPGSLRKEPAQQELAAL
NADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGAAPIQRALWAGDKETGVTIMQMDVGLDTGDMLLKTYLPIED
DDTSATLYEKLALQGPDALLQALEGLANGTLTAEKQDEVLANYAEKLSKEEARLDWRKSATQLWQEVRAFNPWPVSYFEH
QGNTIKVWQTQVSTTSSNAAPGTIISASKKGIEVATGDGVLTLLSMQLPGKKPLSVADILNARGDWFTPNTRLNNEAQ

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI238814322, Length=304, Percent_Identity=28.6184210526316, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI164663775, Length=337, Percent_Identity=29.3768545994065, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21614513, Length=258, Percent_Identity=28.2945736434109, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789683, Length=310, Percent_Identity=66.7741935483871, Blast_Score=427, Evalue=1e-121,
Organism=Escherichia coli, GI1788589, Length=284, Percent_Identity=30.9859154929577, Blast_Score=135, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI133930964, Length=263, Percent_Identity=28.1368821292776, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319458, Length=279, Percent_Identity=28.3154121863799, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45550868, Length=318, Percent_Identity=28.3018867924528, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI28571984, Length=238, Percent_Identity=29.4117647058824, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24585660, Length=239, Percent_Identity=30.5439330543933, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR001555
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 34659; Mature: 34659

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00373 GART

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLNIIFAGTPDFAARHLQALINSHHNVIAVYTQPDRPAGRGKKLTASPVKELAVSHDI
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
PVYQPGSLRKEPAQQELAALNADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGA
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
APIQRALWAGDKETGVTIMQMDVGLDTGDMLLKTYLPIEDDDTSATLYEKLALQGPDALL
CHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHH
QALEGLANGTLTAEKQDEVLANYAEKLSKEEARLDWRKSATQLWQEVRAFNPWPVSYFEH
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHC
QGNTIKVWQTQVSTTSSNAAPGTIISASKKGIEVATGDGVLTLLSMQLPGKKPLSVADIL
CCCEEEEEEEEEECCCCCCCCCEEEECCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHH
NARGDWFTPNTRLNNEAQ
HCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPLNIIFAGTPDFAARHLQALINSHHNVIAVYTQPDRPAGRGKKLTASPVKELAVSHDI
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCC
PVYQPGSLRKEPAQQELAALNADIMVVVAYGLILPKVVLDTPRLGCINVHGSILPRWRGA
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCC
APIQRALWAGDKETGVTIMQMDVGLDTGDMLLKTYLPIEDDDTSATLYEKLALQGPDALL
CHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHH
QALEGLANGTLTAEKQDEVLANYAEKLSKEEARLDWRKSATQLWQEVRAFNPWPVSYFEH
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHC
QGNTIKVWQTQVSTTSSNAAPGTIISASKKGIEVATGDGVLTLLSMQLPGKKPLSVADIL
CCCEEEEEEEEEECCCCCCCCCEEEECCCCCEEEECCCCEEEEEEECCCCCCCCHHHHHH
NARGDWFTPNTRLNNEAQ
HCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA