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The map label for this gene is msrB [H]

Identifier: 117676270

GI number: 117676270

Start: 222837

End: 223277

Strand: Reverse

Name: msrB [H]

Synonym: Shewana3_4333

Alternate gene names: 117676270

Gene position: 223277-222837 (Counterclockwise)

Preceding gene: 117676271

Following gene: 117676269

Centisome position: 80.04

GC content: 49.89

Gene sequence:

>441_bases
ATGTTCAATTGGAAAAGCATTTACAACTACCTGGATAACGGCACTCCCGCGCCTCCCAAAAAAGTAGAAAAGAGCGAGGA
AGAGTGGAAAGAAATTCTGACGCCAGCGCAATTTCGGGTCATGCGGATGAAAGGCACCGAACGCGCGCACACCGGAGAAC
TCTGTTCATTTTATGAAGCTGGAAGGTACGCCTGTGTGGGCTGCGACACCGAACTCTTTGACTCGAACCTAAAGTTCGAT
TCGGGAACGGGATGGCCGAGTTTTTCTGAGCCAGTCGCAGACAACGTAATTCAATATGAACTGGATACGACCTTCGGGCG
CAGAATCGAAGTGCTATGCAATGTGTGCGAAGCCCATCTGGGGCACGCTTTTCCAGACGGTCCTGAGCCATCAGGGGTCC
GATTCTGTATTAACTCGGAGTCATTGAAGTTTGTAGAATAA

Upstream 100 bases:

>100_bases
CCGCAAGTTTTTGTGGATGGAGAATTCATTGGTAGTGCTACAGACTTCTTCTCGTGGATTGATAGCTAAAGAGTGAACCC
TAAAATAAAGGAGCAAATAT

Downstream 100 bases:

>100_bases
TTTTTAAATCGAGGGGGTTTATGAAAGTGAACCTTTTGAAAAAAGGAGCCGTTCGTGTTGATTAAGCTGTTCGGTCATAA
AGACTGCCATAAAACCAAGA

Product: methionine-R-sulfoxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MFNWKSIYNYLDNGTPAPPKKVEKSEEEWKEILTPAQFRVMRMKGTERAHTGELCSFYEAGRYACVGCDTELFDSNLKFD
SGTGWPSFSEPVADNVIQYELDTTFGRRIEVLCNVCEAHLGHAFPDGPEPSGVRFCINSESLKFVE

Sequences:

>Translated_146_residues
MFNWKSIYNYLDNGTPAPPKKVEKSEEEWKEILTPAQFRVMRMKGTERAHTGELCSFYEAGRYACVGCDTELFDSNLKFD
SGTGWPSFSEPVADNVIQYELDTTFGRRIEVLCNVCEAHLGHAFPDGPEPSGVRFCINSESLKFVE
>Mature_146_residues
MFNWKSIYNYLDNGTPAPPKKVEKSEEEWKEILTPAQFRVMRMKGTERAHTGELCSFYEAGRYACVGCDTELFDSNLKFD
SGTGWPSFSEPVADNVIQYELDTTFGRRIEVLCNVCEAHLGHAFPDGPEPSGVRFCINSESLKFVE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI117606353, Length=128, Percent_Identity=53.125, Blast_Score=126, Evalue=7e-30,
Organism=Homo sapiens, GI301336164, Length=126, Percent_Identity=47.6190476190476, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI301336162, Length=126, Percent_Identity=47.6190476190476, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI73089054, Length=126, Percent_Identity=47.6190476190476, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI37620216, Length=126, Percent_Identity=47.6190476190476, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI7706511, Length=89, Percent_Identity=38.2022471910112, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1788077, Length=123, Percent_Identity=50.4065040650407, Blast_Score=126, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI115532676, Length=129, Percent_Identity=48.062015503876, Blast_Score=114, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17553450, Length=129, Percent_Identity=48.062015503876, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319816, Length=129, Percent_Identity=39.5348837209302, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24645799, Length=137, Percent_Identity=42.3357664233577, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=43.75, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=43.75, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI221378664, Length=128, Percent_Identity=43.75, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI221378662, Length=135, Percent_Identity=43.7037037037037, Blast_Score=112, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=39.568345323741, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=39.568345323741, Blast_Score=109, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16560; Mature: 16560

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
4.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFNWKSIYNYLDNGTPAPPKKVEKSEEEWKEILTPAQFRVMRMKGTERAHTGELCSFYEA
CCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHCCHHHHEEEECCCCCCCCHHHHHHHHHC
GRYACVGCDTELFDSNLKFDSGTGWPSFSEPVADNVIQYELDTTFGRRIEVLCNVCEAHL
CCEEEEECCHHHHCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHH
GHAFPDGPEPSGVRFCINSESLKFVE
CCCCCCCCCCCCEEEEECCCCCEECC
>Mature Secondary Structure
MFNWKSIYNYLDNGTPAPPKKVEKSEEEWKEILTPAQFRVMRMKGTERAHTGELCSFYEA
CCCHHHHHHHHHCCCCCCCHHHCCCHHHHHHHCCHHHHEEEECCCCCCCCHHHHHHHHHC
GRYACVGCDTELFDSNLKFDSGTGWPSFSEPVADNVIQYELDTTFGRRIEVLCNVCEAHL
CCEEEEECCHHHHCCCCCCCCCCCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHH
GHAFPDGPEPSGVRFCINSESLKFVE
CCCCCCCCCCCCEEEEECCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA