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The map label for this gene is hsdM [C]

Identifier: 117676179

GI number: 117676179

Start: 113252

End: 114955

Strand: Direct

Name: hsdM [C]

Synonym: Shewana3_4240

Alternate gene names: 117676179

Gene position: 113252-114955 (Clockwise)

Preceding gene: 117676176

Following gene: 117676180

Centisome position: 40.6

GC content: 45.72

Gene sequence:

>1704_bases
ATGAACGAACTAGAACAAGAATTCCTAAAAGATTTAGAAAAGAAGCTGTGGAATGCCGCAGATAAGCTCAGAGCAACGCT
AGACGCTTCGCAATACAAACATGCTGTATTGGGTCTAATCTTCGTAAAATACGTCTCAGACGCCTTCTCAATGCGTCAGG
AAGAGATTAAAGCTGACCTCACTAATCCAGAACATGAGTATTATCTTGATCCGGCTGATTTCTCTGAAGACGAATTGGCA
GAAGAGATCGCAGCCGAACTGGAAGTTCGCGATTTCTACACTGAGAAAAACGTATTCTGGTTACCAACTGAATCTCGTTG
GAAGTTCCTGCAAGACAATGGCCCGATGGTCATTGGTGGTGCCGATTTGGTCATTGATGGTAAGACGAAAAAAATCACGT
CTGTTGGACATCTGATTGATAATGCACTGGAAGGCATTGAGCGCGACAACCAGAAACTAAAAGGTGTTCTCAACAAACAC
TACGCCTCGCTAAAAATTGATCAGGCAAAACTTAATGAGTTGATTAACCTAATCGCGACTATTCCATTCAATCATAAGTC
TCTTAACAGCAAAGATATTCTTGGTCATATTTACGAATACTTCTTAGGCCAATTTGCGCTTGCTGAAGGTAAGAAAGGCG
GCCAGTTCTACACGCCAGCCTCCATCGTTTCGCTGATTGTTGAAATGATTGAACCGTTTGAAGGTCGAGTGTATGACCCT
GCAATGGGGTCTGGTGGCTTCTTTGTGCAATCAGAGAAGTTCATTGAGCGCAGAGCGAATCAAAAAGAAATCGACCCGCT
AACGCAAAAGCAAAGAATCTCGATTTACGGACAGGAATACAACTACACCACATGGCAGCTTGCTGCGATGAATATGGCAA
TTCGTGGCTTGGATTACGATTTCGGTAAAGAGCCTGCCAGTACCTATACCAACGACCAGCATCCTGATTTACGTGCTGAT
TTCATCATGGCGAACCCGCCCTTCAACATGAAAGAGTGGAATACTGGTGTTGATGATAACGATCCACGTTGGGTATACGG
CACACCACCATCAGGTAACGCAAACTTTGCTTGGATGCAGCACATGCTTTACCACCTTGCACCAGATGGTTCTCAAGCCT
TGTTACTTGCCAATGGTTCGATGAGTTCAACCACCAACAACGAAGGTGAAATTCGTGCGGCCTTGGTCGAGAACGATTTG
GTCGAGTGTATGGTTGCGCTTCCGGGGCAACTGTTTACCAACACCCAGATCCCTGCCTGTATCTGGTTCTTAGCCAAAAA
CAAAAAGGCTCGTACCGATAAGTCAGGTCGTAAGCTGCGTGATCGCAAAGGTGAAGTGTTATTTATTGATGCGCGCAACC
TTGGCTATATGAAAGACCGCGTTCTGCGTGATTTCACCCAAGATGATATCCAGAAAGTCGCTGACCTTTACCACGCTTGG
AAAACAGGTGCGGAAGTAAATGGTATCGCTTATGAAGACCAAGCAGGCTTCTGCAAATCAGCAACTTTGGAAGAGATTAA
GAAACACGATTTTGTTCTAACTCCGGGACGTTACGTTGGTGCCACAGAAGAGCTGGACGACGGCATTCCATTCGGTGAGA
AGATGGCAACGCTAACCTCCAAGTTGAGCGATCAGTTTGCCGAGTCAGCCACGTTAGAAGCAGAGATCAAGAAGAACCTA
GCGGGGTTGGGTTATGACCTGTAG

Upstream 100 bases:

>100_bases
CTTTTTCATAGAAAACATTTAAAGTAAGGCACAATCCAATGAAAACGTGCCAATTTCGCGGTATGATTTTCTAACTCAAA
CGTCTTAAAAGTTGCCAGAA

Downstream 100 bases:

>100_bases
TTGGCCTACTGTAACTTTAGATGAGTGTGCATCATTTCAAGAAGGGTATGTAAATCCTACTCAGAAAAAAGAACATTACT
TTGATGGGCCTGTAAAATGG

Product: N-6 DNA methylase

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MNELEQEFLKDLEKKLWNAADKLRATLDASQYKHAVLGLIFVKYVSDAFSMRQEEIKADLTNPEHEYYLDPADFSEDELA
EEIAAELEVRDFYTEKNVFWLPTESRWKFLQDNGPMVIGGADLVIDGKTKKITSVGHLIDNALEGIERDNQKLKGVLNKH
YASLKIDQAKLNELINLIATIPFNHKSLNSKDILGHIYEYFLGQFALAEGKKGGQFYTPASIVSLIVEMIEPFEGRVYDP
AMGSGGFFVQSEKFIERRANQKEIDPLTQKQRISIYGQEYNYTTWQLAAMNMAIRGLDYDFGKEPASTYTNDQHPDLRAD
FIMANPPFNMKEWNTGVDDNDPRWVYGTPPSGNANFAWMQHMLYHLAPDGSQALLLANGSMSSTTNNEGEIRAALVENDL
VECMVALPGQLFTNTQIPACIWFLAKNKKARTDKSGRKLRDRKGEVLFIDARNLGYMKDRVLRDFTQDDIQKVADLYHAW
KTGAEVNGIAYEDQAGFCKSATLEEIKKHDFVLTPGRYVGATEELDDGIPFGEKMATLTSKLSDQFAESATLEAEIKKNL
AGLGYDL

Sequences:

>Translated_567_residues
MNELEQEFLKDLEKKLWNAADKLRATLDASQYKHAVLGLIFVKYVSDAFSMRQEEIKADLTNPEHEYYLDPADFSEDELA
EEIAAELEVRDFYTEKNVFWLPTESRWKFLQDNGPMVIGGADLVIDGKTKKITSVGHLIDNALEGIERDNQKLKGVLNKH
YASLKIDQAKLNELINLIATIPFNHKSLNSKDILGHIYEYFLGQFALAEGKKGGQFYTPASIVSLIVEMIEPFEGRVYDP
AMGSGGFFVQSEKFIERRANQKEIDPLTQKQRISIYGQEYNYTTWQLAAMNMAIRGLDYDFGKEPASTYTNDQHPDLRAD
FIMANPPFNMKEWNTGVDDNDPRWVYGTPPSGNANFAWMQHMLYHLAPDGSQALLLANGSMSSTTNNEGEIRAALVENDL
VECMVALPGQLFTNTQIPACIWFLAKNKKARTDKSGRKLRDRKGEVLFIDARNLGYMKDRVLRDFTQDDIQKVADLYHAW
KTGAEVNGIAYEDQAGFCKSATLEEIKKHDFVLTPGRYVGATEELDDGIPFGEKMATLTSKLSDQFAESATLEAEIKKNL
AGLGYDL
>Mature_567_residues
MNELEQEFLKDLEKKLWNAADKLRATLDASQYKHAVLGLIFVKYVSDAFSMRQEEIKADLTNPEHEYYLDPADFSEDELA
EEIAAELEVRDFYTEKNVFWLPTESRWKFLQDNGPMVIGGADLVIDGKTKKITSVGHLIDNALEGIERDNQKLKGVLNKH
YASLKIDQAKLNELINLIATIPFNHKSLNSKDILGHIYEYFLGQFALAEGKKGGQFYTPASIVSLIVEMIEPFEGRVYDP
AMGSGGFFVQSEKFIERRANQKEIDPLTQKQRISIYGQEYNYTTWQLAAMNMAIRGLDYDFGKEPASTYTNDQHPDLRAD
FIMANPPFNMKEWNTGVDDNDPRWVYGTPPSGNANFAWMQHMLYHLAPDGSQALLLANGSMSSTTNNEGEIRAALVENDL
VECMVALPGQLFTNTQIPACIWFLAKNKKARTDKSGRKLRDRKGEVLFIDARNLGYMKDRVLRDFTQDDIQKVADLYHAW
KTGAEVNGIAYEDQAGFCKSATLEEIKKHDFVLTPGRYVGATEELDDGIPFGEKMATLTSKLSDQFAESATLEAEIKKNL
AGLGYDL

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=296, Percent_Identity=22.6351351351351, Blast_Score=79, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 64070; Mature: 64070

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNELEQEFLKDLEKKLWNAADKLRATLDASQYKHAVLGLIFVKYVSDAFSMRQEEIKADL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TNPEHEYYLDPADFSEDELAEEIAAELEVRDFYTEKNVFWLPTESRWKFLQDNGPMVIGG
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHCHHEEECCCCEEECC
ADLVIDGKTKKITSVGHLIDNALEGIERDNQKLKGVLNKHYASLKIDQAKLNELINLIAT
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHH
IPFNHKSLNSKDILGHIYEYFLGQFALAEGKKGGQFYTPASIVSLIVEMIEPFEGRVYDP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCCEEECC
AMGSGGFFVQSEKFIERRANQKEIDPLTQKQRISIYGQEYNYTTWQLAAMNMAIRGLDYD
CCCCCCEEEECHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHCCCCCC
FGKEPASTYTNDQHPDLRADFIMANPPFNMKEWNTGVDDNDPRWVYGTPPSGNANFAWMQ
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHH
HMLYHLAPDGSQALLLANGSMSSTTNNEGEIRAALVENDLVECMVALPGQLFTNTQIPAC
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCCHHE
IWFLAKNKKARTDKSGRKLRDRKGEVLFIDARNLGYMKDRVLRDFTQDDIQKVADLYHAW
EEEEECCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
KTGAEVNGIAYEDQAGFCKSATLEEIKKHDFVLTPGRYVGATEELDDGIPFGEKMATLTS
HCCCCCCCEEECCCCCCCHHHHHHHHHHCCEEECCCCCCCCCHHHCCCCCCCHHHHHHHH
KLSDQFAESATLEAEIKKNLAGLGYDL
HHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNELEQEFLKDLEKKLWNAADKLRATLDASQYKHAVLGLIFVKYVSDAFSMRQEEIKADL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TNPEHEYYLDPADFSEDELAEEIAAELEVRDFYTEKNVFWLPTESRWKFLQDNGPMVIGG
CCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHCHHEEECCCCEEECC
ADLVIDGKTKKITSVGHLIDNALEGIERDNQKLKGVLNKHYASLKIDQAKLNELINLIAT
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHH
IPFNHKSLNSKDILGHIYEYFLGQFALAEGKKGGQFYTPASIVSLIVEMIEPFEGRVYDP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHHCCCCCEEECC
AMGSGGFFVQSEKFIERRANQKEIDPLTQKQRISIYGQEYNYTTWQLAAMNMAIRGLDYD
CCCCCCEEEECHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCEEEHHHHHHHHCCCCCC
FGKEPASTYTNDQHPDLRADFIMANPPFNMKEWNTGVDDNDPRWVYGTPPSGNANFAWMQ
CCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHH
HMLYHLAPDGSQALLLANGSMSSTTNNEGEIRAALVENDLVECMVALPGQLFTNTQIPAC
HHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHCCCCCHHE
IWFLAKNKKARTDKSGRKLRDRKGEVLFIDARNLGYMKDRVLRDFTQDDIQKVADLYHAW
EEEEECCCCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
KTGAEVNGIAYEDQAGFCKSATLEEIKKHDFVLTPGRYVGATEELDDGIPFGEKMATLTS
HCCCCCCCEEECCCCCCCHHHHHHHHHHCCEEECCCCCCCCCHHHCCCCCCCHHHHHHHH
KLSDQFAESATLEAEIKKNLAGLGYDL
HHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]