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The map label for this gene is umuC [H]

Identifier: 117676112

GI number: 117676112

Start: 38365

End: 39615

Strand: Reverse

Name: umuC [H]

Synonym: Shewana3_4172

Alternate gene names: 117676112

Gene position: 39615-38365 (Counterclockwise)

Preceding gene: 117676113

Following gene: 117676108

Centisome position: 14.2

GC content: 47.32

Gene sequence:

>1251_bases
ATGAGCAGCATAATAGCGTTATGCGATGGGAATAAGTTTTACAGCTCATGCGAACAGATTTTTAACCCGCAGTATCGTGG
TAAGCCTCTAATTGTGGTCTCGAACAATGACGGCATGACAGTGACGTTAAGCCCTGAAGCGGCTGCGTTGGGGCTTAAAA
AATTCACGCCTTACTTTCAAGTTGCTGAGTTCTGTAGGGCGAATGGCGTGGTTGTTTGCTCGAGCAATTACGCCTTGTAT
TCAGAAATCAGCTCTCAGTTTATGAAAGTCGCATCGAGAGAGTGTTTTTCGTATTTTCCCTATTCGATAGACGAGATTTT
TGCTGAATTTGGGAATGATGACACACCACAGAACCTCTCAATATTAGGCCGCAAGCTCAGGCACGATGTCTGGCGCGAGG
TCCGATTGCCTATTGGTGTCGGGCTAGGGGATACCTTAACGCTGGCGAAAGCCGCAAATCATGCAGCGAAGCGCTTAGGC
TATCGCGGTGTTTGCGTGATTAAAGCGCACAATCGCGAAGCCATCTTAGGGGCGATGTTGACTACCGATGTGTGGGGAGT
GGGTAAACGAATTGGTCAGCGGCTAAGTTCGATGGGGATTCATACTGCGCTGCAGTTGGCCCAAATGAAGACTAAGACCG
CGAGGAAAATGTTTGGCGTTAACATCGAAAGAACAATTTTCAAATTGAATGGGACAAAGGCGTTTAACTGGGACGATATG
CCCGTTAATAAGCGACAGATATTCTCCACACGCTCAGTTGGCCAGCGAATAACGACGATAGAGGGGTTAAAAGAGGCGTT
GTCATTCCATGCGTGTGAAGCGGCTCGAAAGCTAAGGGGTCAAAAATCGGTAGCACGTTGCTTGGTATTTTTTGCTCAAA
CATCCGCGTATGACAAGCATGGTGTTAGTGGTTTCAGTCGGACAATTCATTTACCAGCCCCCACCAGTGACAGCATGATT
ATCAGTCAGCAAATTACCTCTGCGGTTGAGTCATTTTATGCCGCAGTGCCGTACTATCGCGTTGGGGTAGGGCTATTAGA
TATAGAACCAGGCTTGCAGCTCGATATGTTCAACGACAACCTGGGAAAACCAGCGTTGATGTCAGTCATGGACAGATTAA
ACGAGCAAATGGGCAAAGGTGCCGTGTTCGTCGCTGCCAATGGCATTGAGAAAAAATGGCAGATGCGGCGAGCGTTCTTG
AGTCCATCTTATCTAACAAATTGGAATGAAATTCCAACCATTCACTGTTAG

Upstream 100 bases:

>100_bases
ACGATTTTGAGCCGGTATCAATTAGGCTTGATGACCGCTTCTGGTGCGAAGGGGTCGTGCCAGCATCCATTAGATTATTG
AAACAACCGAGTTTATTGGT

Downstream 100 bases:

>100_bases
CAACGTAGTAAAATTTGCCTCATTTAAAGCTTGTGTGATGATTACTCTCAACGAATTTAGGAGAGCATCATGCGGTTAAA
ATCAGATTTTGAGTTTTCAT

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSSIIALCDGNKFYSSCEQIFNPQYRGKPLIVVSNNDGMTVTLSPEAAALGLKKFTPYFQVAEFCRANGVVVCSSNYALY
SEISSQFMKVASRECFSYFPYSIDEIFAEFGNDDTPQNLSILGRKLRHDVWREVRLPIGVGLGDTLTLAKAANHAAKRLG
YRGVCVIKAHNREAILGAMLTTDVWGVGKRIGQRLSSMGIHTALQLAQMKTKTARKMFGVNIERTIFKLNGTKAFNWDDM
PVNKRQIFSTRSVGQRITTIEGLKEALSFHACEAARKLRGQKSVARCLVFFAQTSAYDKHGVSGFSRTIHLPAPTSDSMI
ISQQITSAVESFYAAVPYYRVGVGLLDIEPGLQLDMFNDNLGKPALMSVMDRLNEQMGKGAVFVAANGIEKKWQMRRAFL
SPSYLTNWNEIPTIHC

Sequences:

>Translated_416_residues
MSSIIALCDGNKFYSSCEQIFNPQYRGKPLIVVSNNDGMTVTLSPEAAALGLKKFTPYFQVAEFCRANGVVVCSSNYALY
SEISSQFMKVASRECFSYFPYSIDEIFAEFGNDDTPQNLSILGRKLRHDVWREVRLPIGVGLGDTLTLAKAANHAAKRLG
YRGVCVIKAHNREAILGAMLTTDVWGVGKRIGQRLSSMGIHTALQLAQMKTKTARKMFGVNIERTIFKLNGTKAFNWDDM
PVNKRQIFSTRSVGQRITTIEGLKEALSFHACEAARKLRGQKSVARCLVFFAQTSAYDKHGVSGFSRTIHLPAPTSDSMI
ISQQITSAVESFYAAVPYYRVGVGLLDIEPGLQLDMFNDNLGKPALMSVMDRLNEQMGKGAVFVAANGIEKKWQMRRAFL
SPSYLTNWNEIPTIHC
>Mature_415_residues
SSIIALCDGNKFYSSCEQIFNPQYRGKPLIVVSNNDGMTVTLSPEAAALGLKKFTPYFQVAEFCRANGVVVCSSNYALYS
EISSQFMKVASRECFSYFPYSIDEIFAEFGNDDTPQNLSILGRKLRHDVWREVRLPIGVGLGDTLTLAKAANHAAKRLGY
RGVCVIKAHNREAILGAMLTTDVWGVGKRIGQRLSSMGIHTALQLAQMKTKTARKMFGVNIERTIFKLNGTKAFNWDDMP
VNKRQIFSTRSVGQRITTIEGLKEALSFHACEAARKLRGQKSVARCLVFFAQTSAYDKHGVSGFSRTIHLPAPTSDSMII
SQQITSAVESFYAAVPYYRVGVGLLDIEPGLQLDMFNDNLGKPALMSVMDRLNEQMGKGAVFVAANGIEKKWQMRRAFLS
PSYLTNWNEIPTIHC

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=418, Percent_Identity=37.5598086124402, Blast_Score=280, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 46209; Mature: 46078

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIIALCDGNKFYSSCEQIFNPQYRGKPLIVVSNNDGMTVTLSPEAAALGLKKFTPYFQ
CCCEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHCCHHHH
VAEFCRANGVVVCSSNYALYSEISSQFMKVASRECFSYFPYSIDEIFAEFGNDDTPQNLS
HHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
ILGRKLRHDVWREVRLPIGVGLGDTLTLAKAANHAAKRLGYRGVCVIKAHNREAILGAML
HHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
TTDVWGVGKRIGQRLSSMGIHTALQLAQMKTKTARKMFGVNIERTIFKLNGTKAFNWDDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCEECCCCCC
PVNKRQIFSTRSVGQRITTIEGLKEALSFHACEAARKLRGQKSVARCLVFFAQTSAYDKH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
GVSGFSRTIHLPAPTSDSMIISQQITSAVESFYAAVPYYRVGVGLLDIEPGLQLDMFNDN
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEEEECCCCEEEECCCC
LGKPALMSVMDRLNEQMGKGAVFVAANGIEKKWQMRRAFLSPSYLTNWNEIPTIHC
CCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCCCCC
>Mature Secondary Structure 
SSIIALCDGNKFYSSCEQIFNPQYRGKPLIVVSNNDGMTVTLSPEAAALGLKKFTPYFQ
CCEEEEECCCHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHCCHHHH
VAEFCRANGVVVCSSNYALYSEISSQFMKVASRECFSYFPYSIDEIFAEFGNDDTPQNLS
HHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHH
ILGRKLRHDVWREVRLPIGVGLGDTLTLAKAANHAAKRLGYRGVCVIKAHNREAILGAML
HHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
TTDVWGVGKRIGQRLSSMGIHTALQLAQMKTKTARKMFGVNIERTIFKLNGTKAFNWDDM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCEECCCCCC
PVNKRQIFSTRSVGQRITTIEGLKEALSFHACEAARKLRGQKSVARCLVFFAQTSAYDKH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCC
GVSGFSRTIHLPAPTSDSMIISQQITSAVESFYAAVPYYRVGVGLLDIEPGLQLDMFNDN
CCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEEEECCCCEEEECCCC
LGKPALMSVMDRLNEQMGKGAVFVAANGIEKKWQMRRAFLSPSYLTNWNEIPTIHC
CCCHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2989817; 2989816; 8905232; 9278503; 1320188 [H]