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The map label for this gene is ycjW [H]

Identifier: 116874187

GI number: 116874187

Start: 2805149

End: 2806174

Strand: Direct

Name: ycjW [H]

Synonym: lwe2771

Alternate gene names: 116874187

Gene position: 2805149-2806174 (Clockwise)

Preceding gene: 116874175

Following gene: 116874190

Centisome position: 99.68

GC content: 35.77

Gene sequence:

>1026_bases
TTGGCAGCAACTATTTATGACATAGCAAAACATGCGGGAGTTTCAAAATCAACGGTATCTAGAGTACTAAATAATCAAGC
TAACATCTCTAAAGAATCCAGAAAAAAAGTATTAGCAGCAATTGATGAACTGAACTACCAACCAAGCAAATTAGCACGTG
CTCTCACTTCTTCAGGGTTTGATGCTATCATGGTAATCTCCAATCGCTCTACTACAACAACAACTGGAAATCCGTTTTTT
TCGGAAATAATTCAATCCATTTCCACTCAAGCTGAGTTGGAAAATTTTGACTTGATTCTTCAAACTGCTAAAAATAGCGA
AGACGAACTGAAAAAATGTCTTTCAAAAATTCAAGAAAAAATGATTAAAGGAATAATTATGCTCAGTTCACCAGCTGACG
AAGATTTTTTTCATCAATTAGACCCATATAATATTCCTATTGTTGTTACAGGAAAAGTAGAAGGCCATTATAAAAACATT
TATTCTGTTGACACAGACAATTTTGGCGACAGTTATGCCTTAACTAAACATTTGATTACTCAAGGTCATAAAAAAATCGC
TTGTATTCATGCACCACTTGATTACCACGTTTCAATCGATCGGCTCGCTGGTTTTCGTAGCTGTTTGTTTGACCACCAGT
TAGACCTTCGAAGTGACTGGATTATTGATAGCGGTTATAGTATTGAAGATAGCTATAAAGCCGCATTGAGGCTGATGGAA
GGACATGACAAACCGACAGCAGTTTTTGCAACAGATGATTTAAAAGTTCTTAGCGTCTATAAAATGGCAGCTGATAAAAA
CTTGCAAATTCCTGCAGATTTTTCTATCATAGGCTATAATGATAAGGTCGCTTCAGCATTTCTATCACCACCACTCACTT
CCATAGATATTCCAATCAACAAACTTGGAAGGAAAGCGACTAACTTATTATTCCGCTTAATTCACCAAGACAAAAACGTA
CCAAAAACAACCATTATCCAAACCGAAATGATTGAACGTGAATCCATTCAGAAAATAAACACCTAA

Upstream 100 bases:

>100_bases
CATCTAGTTGGACATTTACTTGGAAATTGAGTAAGATAAATATGGATGCTAATGACCGGAACCGATACCGGCAAGAAGAT
AGAGAGAAAGGAAGATTACC

Downstream 100 bases:

>100_bases
GCTTATTTTCTGAATTTACTTGGTCCTGTAGCTCAGTTGGGAGAGTATCACCTTGACATGGTGGGGGTCGCTGGTTCGAG
ACCAGTCGGGACCATTTATC

Product: LacI family transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MAATIYDIAKHAGVSKSTVSRVLNNQANISKESRKKVLAAIDELNYQPSKLARALTSSGFDAIMVISNRSTTTTTGNPFF
SEIIQSISTQAELENFDLILQTAKNSEDELKKCLSKIQEKMIKGIIMLSSPADEDFFHQLDPYNIPIVVTGKVEGHYKNI
YSVDTDNFGDSYALTKHLITQGHKKIACIHAPLDYHVSIDRLAGFRSCLFDHQLDLRSDWIIDSGYSIEDSYKAALRLME
GHDKPTAVFATDDLKVLSVYKMAADKNLQIPADFSIIGYNDKVASAFLSPPLTSIDIPINKLGRKATNLLFRLIHQDKNV
PKTTIIQTEMIERESIQKINT

Sequences:

>Translated_341_residues
MAATIYDIAKHAGVSKSTVSRVLNNQANISKESRKKVLAAIDELNYQPSKLARALTSSGFDAIMVISNRSTTTTTGNPFF
SEIIQSISTQAELENFDLILQTAKNSEDELKKCLSKIQEKMIKGIIMLSSPADEDFFHQLDPYNIPIVVTGKVEGHYKNI
YSVDTDNFGDSYALTKHLITQGHKKIACIHAPLDYHVSIDRLAGFRSCLFDHQLDLRSDWIIDSGYSIEDSYKAALRLME
GHDKPTAVFATDDLKVLSVYKMAADKNLQIPADFSIIGYNDKVASAFLSPPLTSIDIPINKLGRKATNLLFRLIHQDKNV
PKTTIIQTEMIERESIQKINT
>Mature_340_residues
AATIYDIAKHAGVSKSTVSRVLNNQANISKESRKKVLAAIDELNYQPSKLARALTSSGFDAIMVISNRSTTTTTGNPFFS
EIIQSISTQAELENFDLILQTAKNSEDELKKCLSKIQEKMIKGIIMLSSPADEDFFHQLDPYNIPIVVTGKVEGHYKNIY
SVDTDNFGDSYALTKHLITQGHKKIACIHAPLDYHVSIDRLAGFRSCLFDHQLDLRSDWIIDSGYSIEDSYKAALRLMEG
HDKPTAVFATDDLKVLSVYKMAADKNLQIPADFSIIGYNDKVASAFLSPPLTSIDIPINKLGRKATNLLFRLIHQDKNVP
KTTIIQTEMIERESIQKINT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787580, Length=330, Percent_Identity=59.3939393939394, Blast_Score=413, Evalue=1e-117,
Organism=Escherichia coli, GI1787948, Length=335, Percent_Identity=30.7462686567164, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1790194, Length=320, Percent_Identity=30.9375, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1790369, Length=340, Percent_Identity=29.1176470588235, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1789068, Length=341, Percent_Identity=27.5659824046921, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1786540, Length=347, Percent_Identity=26.8011527377522, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=27.6527331189711, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789202, Length=300, Percent_Identity=27, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787906, Length=339, Percent_Identity=21.5339233038348, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994940, Length=324, Percent_Identity=25.3086419753086, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786268, Length=298, Percent_Identity=23.8255033557047, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790689, Length=332, Percent_Identity=22.5903614457831, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38059; Mature: 37928

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAATIYDIAKHAGVSKSTVSRVLNNQANISKESRKKVLAAIDELNYQPSKLARALTSSGF
CCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
DAIMVISNRSTTTTTGNPFFSEIIQSISTQAELENFDLILQTAKNSEDELKKCLSKIQEK
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHH
MIKGIIMLSSPADEDFFHQLDPYNIPIVVTGKVEGHYKNIYSVDTDNFGDSYALTKHLIT
HHHCEEEECCCCCHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
QGHKKIACIHAPLDYHVSIDRLAGFRSCLFDHQLDLRSDWIIDSGYSIEDSYKAALRLME
CCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHH
GHDKPTAVFATDDLKVLSVYKMAADKNLQIPADFSIIGYNDKVASAFLSPPLTSIDIPIN
CCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHCCCCCEECCCHH
KLGRKATNLLFRLIHQDKNVPKTTIIQTEMIERESIQKINT
HHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AATIYDIAKHAGVSKSTVSRVLNNQANISKESRKKVLAAIDELNYQPSKLARALTSSGF
CCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
DAIMVISNRSTTTTTGNPFFSEIIQSISTQAELENFDLILQTAKNSEDELKKCLSKIQEK
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHH
MIKGIIMLSSPADEDFFHQLDPYNIPIVVTGKVEGHYKNIYSVDTDNFGDSYALTKHLIT
HHHCEEEECCCCCHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
QGHKKIACIHAPLDYHVSIDRLAGFRSCLFDHQLDLRSDWIIDSGYSIEDSYKAALRLME
CCCCEEEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHH
GHDKPTAVFATDDLKVLSVYKMAADKNLQIPADFSIIGYNDKVASAFLSPPLTSIDIPIN
CCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHCCCCCEECCCHH
KLGRKATNLLFRLIHQDKNVPKTTIIQTEMIERESIQKINT
HHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]