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The map label for this gene is bglK [H]

Identifier: 116874127

GI number: 116874127

Start: 2746170

End: 2747054

Strand: Direct

Name: bglK [H]

Synonym: lwe2711

Alternate gene names: 116874127

Gene position: 2746170-2747054 (Clockwise)

Preceding gene: 116874126

Following gene: 116874128

Centisome position: 97.59

GC content: 44.07

Gene sequence:

>885_bases
ATGAAAATTGCAGCTTTTGATATCGGTGGAACGGCCCTTAAAATGGGGGTCGTTTTGCCGCATGGTGAAATTATTTTAAC
AAAATCAGCCGAAATTAGTGGTAGCGACGGTGAGCAAATTTTAGCAGAAATGAAAGTGTTTCTTGCTGAAAATACGGATG
TGACGGGCATCGCAGTCAGCGCACCGGGCTATGTGAATCCGAAAACTGGGCTTATCACAATGGGCGGCGCTATCCGTAGA
TTTGATAACTTTAATTTGAAAGAATGGCTCGAAGCTGAAACTGGGCTTCCTGTTGCCATCGAAAATGACGCTAATTGTGC
CCTACTTGCTGAAAAGTGGCTTGGTAAAGGGCAAGAATTAGATGATTTTCTTTGTTTAACTATTGGTACTGGAATTGGTG
GTGGGATCTTTTCTAACGGTGAGCTAGTTCGTGGCGGTCGTTTCCGCGCTGGTGAATTTGGTTATATGTTTAGCGAACGT
CCTGGTGCTTTTCGGCCTGGTAGATATACCCTAAACGAAACTACAACCATGCTCGTTCTTCGTAGACAATACGCGGAACT
TACTGGGCGCCCTTTGGAAGAGATTACTGGTGAAGAAATTTTTGCTAATTATGACGCGCACGACGCCGTCTCAGAACGAC
TTGTTACTGAGTTTTATACCGGGATTTGTACGGGGCTTTATAATTTAATTTACCTGTTCGATCCAACGCACATTTTTATC
GGTGGCGGAATTACAAGCCGCCCTACTTTTATCGCGGAGCTAAAGCATCATATGGAGAGCTTTGGACTTCGTGACACAAT
TATCGAAACAGCTACACATAAAAACCAAGCTGGCCTACTCGGCGCAGTGTATCACTTTTTACAGGAGGAAAATAAACATG
GATGA

Upstream 100 bases:

>100_bases
TTTATCTACCATTCGTACTTGTATCTAACAAAATTGCCGCGAGTGATGCTGCAATGGACAAAAATGCAACAGCCTCAACG
GAACAATAGGATGTGACAAA

Downstream 100 bases:

>100_bases
AATGGAAACAGTCATTTTTGGCATGATTAGCCAAGTTGGTTCTGCGAGAAGCAGTTACTTAGAAGGGCTTCGTGCGGCTC
GTGAAGGCAATTTCGAGGAA

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGEQILAEMKVFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRR
FDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQELDDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSER
PGAFRPGRYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFANYDAHDAVSERLVTEFYTGICTGLYNLIYLFDPTHIFI
GGGITSRPTFIAELKHHMESFGLRDTIIETATHKNQAGLLGAVYHFLQEENKHG

Sequences:

>Translated_294_residues
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGEQILAEMKVFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRR
FDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQELDDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSER
PGAFRPGRYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFANYDAHDAVSERLVTEFYTGICTGLYNLIYLFDPTHIFI
GGGITSRPTFIAELKHHMESFGLRDTIIETATHKNQAGLLGAVYHFLQEENKHG
>Mature_294_residues
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGEQILAEMKVFLAENTDVTGIAVSAPGYVNPKTGLITMGGAIRR
FDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQELDDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSER
PGAFRPGRYTLNETTTMLVLRRQYAELTGRPLEEITGEEIFANYDAHDAVSERLVTEFYTGICTGLYNLIYLFDPTHIFI
GGGITSRPTFIAELKHHMESFGLRDTIIETATHKNQAGLLGAVYHFLQEENKHG

Specific function: Catalyzes the ATP-dependent phosphorylation of cellobiose to produce cellobiose-6'-P. May have a dual role of kinase and transcriptional regulator of the cellobiose-PTS operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=271, Percent_Identity=26.5682656826568, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI298566325, Length=271, Percent_Identity=26.5682656826568, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI190014632, Length=271, Percent_Identity=26.5682656826568, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4885285, Length=271, Percent_Identity=26.5682656826568, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1787363, Length=311, Percent_Identity=25.7234726688103, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081733, Length=311, Percent_Identity=23.1511254019293, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082127, Length=196, Percent_Identity=25.5102040816327, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.85 [H]

Molecular weight: Translated: 32133; Mature: 32133

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGEQILAEMKVFLAENTDVTGIAVS
CEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
APGYVNPKTGLITMGGAIRRFDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQEL
CCCCCCCCCCEEECCCHHHHHCCCCHHHHHHHCCCCCEEEECCCCEEEEEHHHCCCCCCC
DDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSERPGAFRPGRYTLNETTTMLVL
CCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCCCCEEECCHHHHHHH
RRQYAELTGRPLEEITGEEIFANYDAHDAVSERLVTEFYTGICTGLYNLIYLFDPTHIFI
HHHHHHHCCCCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEE
GGGITSRPTFIAELKHHMESFGLRDTIIETATHKNQAGLLGAVYHFLQEENKHG
ECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIAAFDIGGTALKMGVVLPHGEIILTKSAEISGSDGEQILAEMKVFLAENTDVTGIAVS
CEEEEEECCCCEEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEE
APGYVNPKTGLITMGGAIRRFDNFNLKEWLEAETGLPVAIENDANCALLAEKWLGKGQEL
CCCCCCCCCCEEECCCHHHHHCCCCHHHHHHHCCCCCEEEECCCCEEEEEHHHCCCCCCC
DDFLCLTIGTGIGGGIFSNGELVRGGRFRAGEFGYMFSERPGAFRPGRYTLNETTTMLVL
CCEEEEEECCCCCCCCCCCCCEEECCCCCCCCCCEEECCCCCCCCCCCEEECCHHHHHHH
RRQYAELTGRPLEEITGEEIFANYDAHDAVSERLVTEFYTGICTGLYNLIYLFDPTHIFI
HHHHHHHCCCCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCEEEE
GGGITSRPTFIAELKHHMESFGLRDTIIETATHKNQAGLLGAVYHFLQEENKHG
ECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669; 12110692 [H]