| Definition | Listeria welshimeri serovar 6b str. SLCC5334, complete genome. |
|---|---|
| Accession | NC_008555 |
| Length | 2,814,130 |
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The map label for this gene is yvgN [H]
Identifier: 116874067
GI number: 116874067
Start: 2683955
End: 2684797
Strand: Direct
Name: yvgN [H]
Synonym: lwe2651
Alternate gene names: 116874067
Gene position: 2683955-2684797 (Clockwise)
Preceding gene: 116874065
Following gene: 116874076
Centisome position: 95.37
GC content: 40.09
Gene sequence:
>843_bases ATGACACTTTCTTTCTCGGATACATACAAATTGAACAATGGAATTGAAATGCCTAGACATGGTTTTGGAGTCTACAAGCT CACTGACGAAAAGCGTATGCGTACAGCTTTGGAAACTGCTGTAGACGTTGGATATCGCTTGTTTGATACGGCTTCATTTT ACCATAATGAAAAAGAACTCGGAGACTTTTTTGCATCAAGTGGCTTAAAACGTGACGAGTTTTTTGTAACGACAAAAATG TGGAATACGGAGCAAGGCTACGACGAGACGCTTCGTGCTTTTGAAAAATCTCAGAAGAAACTACAACTAGATCAAATTGA TTTATATTTAGTTCATTGGCCTAAACAAGATACATTTTTTGAAACATGGCGAGCTGTGGAAAAACTATATGATGAAGGGC TTGTTCGCGCTATCGGAGTAAGTAATTTTGAAGCGCATCACTTGGATCGTCTTCGCACAAGCGCAAATGTTCTTCCAGTG GTTGATCAACTTGAAACGCATCCGCACTTTCCAAACCGTTTATTGCATCGTTACTTAGAAGAGTTACATATTGTTCACCA AGCGTGGAGCCCACTCGGTCGCGGCGGAGTACTAGAAGAGCAAATTCTTATTGACTTAGCAAAAAAACACGGAAAATCGC CTGCACAAATTGTTCTTCGTTGGCATTTGCAAAACAATATCTCGATTATTCCAAAATCTGAAACACCTTCCAGAATCAAA GAAAATGCAGCAATTTATGATTTTGAATTAACAGAAGCGGATATGCATCAAGTTGACCGCTTAAATAATGGCGAACGCGT TAGCCACGCCCCAGACGTAATGTACGTCCGCTCTGAAATTTAA
Upstream 100 bases:
>100_bases ATATATAAAAAATTTTCTACAAATTCGCCCCTTCTTTCTACAGAAATGATCCATTTTCTGGTATGCTTAAATTAATAAAC TAAAGTAGGAGGCTATTTAA
Downstream 100 bases:
>100_bases AATAAAAAATCTACTATTCCGAAATGGTTTAGTAGATTTTTTATTTATTTCTTTAATTGTCTTGTTCTAGCTTCTTTAAA AAGATAAAAATAGCGCGCTT
Product: aldo/keto reductase family oxidoreductase
Products: NA
Alternate protein names: GR; Methylglyoxal reductase [H]
Number of amino acids: Translated: 280; Mature: 279
Protein sequence:
>280_residues MTLSFSDTYKLNNGIEMPRHGFGVYKLTDEKRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASSGLKRDEFFVTTKM WNTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPV VDQLETHPHFPNRLLHRYLEELHIVHQAWSPLGRGGVLEEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIK ENAAIYDFELTEADMHQVDRLNNGERVSHAPDVMYVRSEI
Sequences:
>Translated_280_residues MTLSFSDTYKLNNGIEMPRHGFGVYKLTDEKRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASSGLKRDEFFVTTKM WNTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPV VDQLETHPHFPNRLLHRYLEELHIVHQAWSPLGRGGVLEEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIK ENAAIYDFELTEADMHQVDRLNNGERVSHAPDVMYVRSEI >Mature_279_residues TLSFSDTYKLNNGIEMPRHGFGVYKLTDEKRMRTALETAVDVGYRLFDTASFYHNEKELGDFFASSGLKRDEFFVTTKMW NTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFFETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVV DQLETHPHFPNRLLHRYLEELHIVHQAWSPLGRGGVLEEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIKE NAAIYDFELTEADMHQVDRLNNGERVSHAPDVMYVRSEI
Specific function: Reduces glyoxal and methylglyoxal. Is not involved in the vitamin B6 biosynthesis [H]
COG id: COG0656
COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the aldo/keto reductase family [H]
Homologues:
Organism=Homo sapiens, GI24497577, Length=291, Percent_Identity=36.426116838488, Blast_Score=192, Evalue=3e-49, Organism=Homo sapiens, GI5174391, Length=291, Percent_Identity=36.426116838488, Blast_Score=192, Evalue=3e-49, Organism=Homo sapiens, GI223468663, Length=295, Percent_Identity=33.2203389830508, Blast_Score=177, Evalue=6e-45, Organism=Homo sapiens, GI93277124, Length=307, Percent_Identity=35.1791530944625, Blast_Score=176, Evalue=2e-44, Organism=Homo sapiens, GI5453543, Length=298, Percent_Identity=34.2281879194631, Blast_Score=169, Evalue=2e-42, Organism=Homo sapiens, GI310109922, Length=278, Percent_Identity=34.8920863309352, Blast_Score=168, Evalue=5e-42, Organism=Homo sapiens, GI310109920, Length=298, Percent_Identity=33.8926174496644, Blast_Score=167, Evalue=9e-42, Organism=Homo sapiens, GI291291012, Length=272, Percent_Identity=33.0882352941176, Blast_Score=166, Evalue=3e-41, Organism=Homo sapiens, GI45446745, Length=298, Percent_Identity=33.5570469798658, Blast_Score=165, Evalue=4e-41, Organism=Homo sapiens, GI4503285, Length=298, Percent_Identity=33.5570469798658, Blast_Score=165, Evalue=4e-41, Organism=Homo sapiens, GI24497583, Length=295, Percent_Identity=34.5762711864407, Blast_Score=162, Evalue=3e-40, Organism=Homo sapiens, GI4502049, Length=294, Percent_Identity=35.7142857142857, Blast_Score=162, Evalue=5e-40, Organism=Homo sapiens, GI24497585, Length=296, Percent_Identity=34.1216216216216, Blast_Score=160, Evalue=1e-39, Organism=Homo sapiens, GI5174695, Length=296, Percent_Identity=32.4324324324324, Blast_Score=158, Evalue=4e-39, Organism=Homo sapiens, GI300116273, Length=272, Percent_Identity=31.6176470588235, Blast_Score=140, Evalue=1e-33, Organism=Homo sapiens, GI300116271, Length=276, Percent_Identity=30.7971014492754, Blast_Score=124, Evalue=1e-28, Organism=Homo sapiens, GI310109924, Length=154, Percent_Identity=35.7142857142857, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI310109926, Length=128, Percent_Identity=35.9375, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI207028673, Length=128, Percent_Identity=35.15625, Blast_Score=82, Evalue=5e-16, Organism=Escherichia coli, GI87082198, Length=267, Percent_Identity=43.4456928838951, Blast_Score=235, Evalue=2e-63, Organism=Escherichia coli, GI1786400, Length=257, Percent_Identity=28.4046692607004, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI1788081, Length=266, Percent_Identity=29.6992481203008, Blast_Score=115, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17561298, Length=287, Percent_Identity=39.7212543554007, Blast_Score=202, Evalue=1e-52, Organism=Caenorhabditis elegans, GI71998625, Length=267, Percent_Identity=38.9513108614232, Blast_Score=197, Evalue=5e-51, Organism=Caenorhabditis elegans, GI17564128, Length=300, Percent_Identity=36, Blast_Score=191, Evalue=5e-49, Organism=Caenorhabditis elegans, GI17537077, Length=295, Percent_Identity=34.5762711864407, Blast_Score=176, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17537075, Length=295, Percent_Identity=34.2372881355932, Blast_Score=172, Evalue=2e-43, Organism=Caenorhabditis elegans, GI17538386, Length=273, Percent_Identity=32.6007326007326, Blast_Score=163, Evalue=9e-41, Organism=Caenorhabditis elegans, GI17562292, Length=278, Percent_Identity=33.8129496402878, Blast_Score=162, Evalue=1e-40, Organism=Caenorhabditis elegans, GI17566692, Length=284, Percent_Identity=35.9154929577465, Blast_Score=161, Evalue=3e-40, Organism=Caenorhabditis elegans, GI17550248, Length=298, Percent_Identity=33.8926174496644, Blast_Score=160, Evalue=1e-39, Organism=Caenorhabditis elegans, GI17552492, Length=263, Percent_Identity=31.1787072243346, Blast_Score=152, Evalue=3e-37, Organism=Caenorhabditis elegans, GI17561300, Length=278, Percent_Identity=34.1726618705036, Blast_Score=150, Evalue=1e-36, Organism=Caenorhabditis elegans, GI17537079, Length=303, Percent_Identity=26.4026402640264, Blast_Score=130, Evalue=6e-31, Organism=Saccharomyces cerevisiae, GI6320576, Length=289, Percent_Identity=36.6782006920415, Blast_Score=182, Evalue=4e-47, Organism=Saccharomyces cerevisiae, GI6324694, Length=307, Percent_Identity=34.8534201954397, Blast_Score=168, Evalue=8e-43, Organism=Saccharomyces cerevisiae, GI6322556, Length=262, Percent_Identity=35.8778625954198, Blast_Score=163, Evalue=2e-41, Organism=Saccharomyces cerevisiae, GI6321896, Length=312, Percent_Identity=30.7692307692308, Blast_Score=138, Evalue=9e-34, Organism=Saccharomyces cerevisiae, GI6319625, Length=293, Percent_Identity=30.7167235494881, Blast_Score=134, Evalue=1e-32, Organism=Saccharomyces cerevisiae, GI6320079, Length=297, Percent_Identity=27.9461279461279, Blast_Score=104, Evalue=2e-23, Organism=Drosophila melanogaster, GI24663317, Length=299, Percent_Identity=35.1170568561873, Blast_Score=174, Evalue=8e-44, Organism=Drosophila melanogaster, GI24657054, Length=303, Percent_Identity=34.6534653465347, Blast_Score=170, Evalue=1e-42, Organism=Drosophila melanogaster, GI20129731, Length=292, Percent_Identity=35.6164383561644, Blast_Score=167, Evalue=5e-42, Organism=Drosophila melanogaster, GI24644950, Length=300, Percent_Identity=33.6666666666667, Blast_Score=167, Evalue=7e-42, Organism=Drosophila melanogaster, GI24662789, Length=298, Percent_Identity=32.8859060402685, Blast_Score=162, Evalue=3e-40, Organism=Drosophila melanogaster, GI221378297, Length=320, Percent_Identity=31.5625, Blast_Score=160, Evalue=1e-39, Organism=Drosophila melanogaster, GI45553081, Length=297, Percent_Identity=33.6700336700337, Blast_Score=159, Evalue=2e-39, Organism=Drosophila melanogaster, GI21356425, Length=291, Percent_Identity=34.3642611683849, Blast_Score=157, Evalue=7e-39, Organism=Drosophila melanogaster, GI24662781, Length=276, Percent_Identity=35.8695652173913, Blast_Score=146, Evalue=1e-35, Organism=Drosophila melanogaster, GI24662785, Length=273, Percent_Identity=35.1648351648352, Blast_Score=142, Evalue=3e-34, Organism=Drosophila melanogaster, GI281366140, Length=257, Percent_Identity=32.6848249027237, Blast_Score=132, Evalue=4e-31,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001395 - InterPro: IPR018170 - InterPro: IPR020471 - InterPro: IPR023210 [H]
Pfam domain/function: PF00248 Aldo_ket_red [H]
EC number: =1.1.1.283 [H]
Molecular weight: Translated: 32641; Mature: 32510
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: PS00798 ALDOKETO_REDUCTASE_1 ; PS00062 ALDOKETO_REDUCTASE_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 2.1 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 1.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTLSFSDTYKLNNGIEMPRHGFGVYKLTDEKRMRTALETAVDVGYRLFDTASFYHNEKEL CCCCCCCCEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH GDFFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFF HHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHEECCEEEEEEEECCCCCHHH ETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNRLLHRYLE HHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH ELHIVHQAWSPLGRGGVLEEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIK HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEEEECCCCEEEECCCCHHHHH ENAAIYDFELTEADMHQVDRLNNGERVSHAPDVMYVRSEI CCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEEECCC >Mature Secondary Structure TLSFSDTYKLNNGIEMPRHGFGVYKLTDEKRMRTALETAVDVGYRLFDTASFYHNEKEL CCCCCCCEECCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH GDFFASSGLKRDEFFVTTKMWNTEQGYDETLRAFEKSQKKLQLDQIDLYLVHWPKQDTFF HHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHEECCEEEEEEEECCCCCHHH ETWRAVEKLYDEGLVRAIGVSNFEAHHLDRLRTSANVLPVVDQLETHPHFPNRLLHRYLE HHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH ELHIVHQAWSPLGRGGVLEEQILIDLAKKHGKSPAQIVLRWHLQNNISIIPKSETPSRIK HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEEEECCCCEEEECCCCHHHHH ENAAIYDFELTEADMHQVDRLNNGERVSHAPDVMYVRSEI CCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9639930; 9384377 [H]