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The map label for this gene is uvrX [H]

Identifier: 116874041

GI number: 116874041

Start: 2652480

End: 2653736

Strand: Direct

Name: uvrX [H]

Synonym: lwe2625

Alternate gene names: 116874041

Gene position: 2652480-2653736 (Clockwise)

Preceding gene: 116874040

Following gene: 116874048

Centisome position: 94.26

GC content: 39.22

Gene sequence:

>1257_bases
GTGCGCCGCGTCGTGATATTTTATGTATTGATATTAAATCGTTTTTTCGCCTCCGTTGAGTGTGTTAAACGCAGGTTGAA
TCCCCTTGATGCGTATTTAGTCGTAATGAGCAACGCAGAACGTGCTGGTGGCCTTGTTTTAGCTGCAACGCCAAAAATGA
AACAAGATCATCATATCAAAACCGGATCGAGAATGTATGAATTGCCAACTTGGGATAAACGAATTATTATTGCACCTCCA
CGAATGAAACTATATTTAAAAGTAAACGCGATGATTCAAGCTATATTCAAACGTTATGTTCCCGCTGAGTTTATTCATGT
TTATAGTATTGATGAATGTTTTCTAGATATTACTGGATCGCATTTGTTGTTTGGAAGTACAGAAGAAATCGTTCGCAAAA
TCCAGCGCGATATTTTAGAAGAGTTGCGGCTTTATGTCACAGTGGGAATTGGTGATAACCCGCTTCTAGCCAAGCTTGCA
CTTGATAATGTGGCTAAGAACCGTGATGACGGAATAGCTGAGTGGCGCTATGCAGATGTTCCAGAGACAATTTGGAAGAT
TAGGCATTTGGATGATGTATGCGGAATTGGTCGCCGGACTGTTGTTCGCCTTCAAAAGATGGGGATTTTTAATATGTATC
AACTAAGCCAAACTCCGCCCCCTGTTTTAAAAAAAGCAATGGGAGTTATTGGCGAACAGCTTTATTATCATGCGCACGGA
ATTGATTACAGCCTTTTAAATGAAAAATATGTTCCTGTTAGTAAAAGTTATGGAAAAAGCCAAATCCTTGAAAGAGATTA
CCATGCGTCCGCCGAAGTAGAAATAGTTATTCGCGAAATGGTAGAAGAAGTAGCTATGCGTTTGCGGCAAAACCATGTAG
ATACTGCCGTCATTCATTTAAGTATCGGCTACAGCAAATACAGCATAAAAAAAGGATTTAGCCATCAAGCTAAAATCCCA
TCTACTAGTAGTAGTCATGCGCTTATTCCTTATTTTCTGCAATTATTCCGCCGCTACGATGAACGAGAACCTGTACGCTC
CATTGCCATTTCATGTGGTAAAATCACTTTAAAAACCGGTTTGCAACTCAATTTATTTGAAGATACATCCCATACATTAA
ACCAAGAACAACTTGAAATAACAGTTGATAAAATCCGCACTCGTTATGGTTTTAAATCACTTATGCACGCGAGTAGTTTA
CTAAATGGAGCAACAGGATTAAAACGCTCTGAAATGGTTGGTGGCCATAAAGGTTAA

Upstream 100 bases:

>100_bases
TATCAAAAACTCAGAAGGTATTATTCCACTTTCTTTTTCCGCTATTAGAAATGTAGAAGAAAGGAGTGTCGACAAATGGT
ACAAGTAGAAGATTACAGTC

Downstream 100 bases:

>100_bases
CTTATTCAGGTTTAACACGGAATAAGAAATCCTCTACCATTGTCGCAAATATTTTTGATTGTTCAATTTGCAAATTATGT
CCTGCAAAATCAAGGATAGC

Product: ImpB/MucB/SamB family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MRRVVIFYVLILNRFFASVECVKRRLNPLDAYLVVMSNAERAGGLVLAATPKMKQDHHIKTGSRMYELPTWDKRIIIAPP
RMKLYLKVNAMIQAIFKRYVPAEFIHVYSIDECFLDITGSHLLFGSTEEIVRKIQRDILEELRLYVTVGIGDNPLLAKLA
LDNVAKNRDDGIAEWRYADVPETIWKIRHLDDVCGIGRRTVVRLQKMGIFNMYQLSQTPPPVLKKAMGVIGEQLYYHAHG
IDYSLLNEKYVPVSKSYGKSQILERDYHASAEVEIVIREMVEEVAMRLRQNHVDTAVIHLSIGYSKYSIKKGFSHQAKIP
STSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTGLQLNLFEDTSHTLNQEQLEITVDKIRTRYGFKSLMHASSL
LNGATGLKRSEMVGGHKG

Sequences:

>Translated_418_residues
MRRVVIFYVLILNRFFASVECVKRRLNPLDAYLVVMSNAERAGGLVLAATPKMKQDHHIKTGSRMYELPTWDKRIIIAPP
RMKLYLKVNAMIQAIFKRYVPAEFIHVYSIDECFLDITGSHLLFGSTEEIVRKIQRDILEELRLYVTVGIGDNPLLAKLA
LDNVAKNRDDGIAEWRYADVPETIWKIRHLDDVCGIGRRTVVRLQKMGIFNMYQLSQTPPPVLKKAMGVIGEQLYYHAHG
IDYSLLNEKYVPVSKSYGKSQILERDYHASAEVEIVIREMVEEVAMRLRQNHVDTAVIHLSIGYSKYSIKKGFSHQAKIP
STSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTGLQLNLFEDTSHTLNQEQLEITVDKIRTRYGFKSLMHASSL
LNGATGLKRSEMVGGHKG
>Mature_418_residues
MRRVVIFYVLILNRFFASVECVKRRLNPLDAYLVVMSNAERAGGLVLAATPKMKQDHHIKTGSRMYELPTWDKRIIIAPP
RMKLYLKVNAMIQAIFKRYVPAEFIHVYSIDECFLDITGSHLLFGSTEEIVRKIQRDILEELRLYVTVGIGDNPLLAKLA
LDNVAKNRDDGIAEWRYADVPETIWKIRHLDDVCGIGRRTVVRLQKMGIFNMYQLSQTPPPVLKKAMGVIGEQLYYHAHG
IDYSLLNEKYVPVSKSYGKSQILERDYHASAEVEIVIREMVEEVAMRLRQNHVDTAVIHLSIGYSKYSIKKGFSHQAKIP
STSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTGLQLNLFEDTSHTLNQEQLEITVDKIRTRYGFKSLMHASSL
LNGATGLKRSEMVGGHKG

Specific function: Poorly Processive, Error-Prone DNA Polymerase Involved In Untargeted Mutagenesis. Copies Undamaged DNA At Stalled Replication Forks, Which Arise In Vivo From Mismatched Or Misaligned Primer Ends. These Misaligned Primers Can Be Extended By Poliv. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1786425, Length=281, Percent_Identity=28.1138790035587, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787432, Length=421, Percent_Identity=24.7030878859857, Blast_Score=83, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: 2.7.7.7 [C]

Molecular weight: Translated: 47796; Mature: 47796

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVVIFYVLILNRFFASVECVKRRLNPLDAYLVVMSNAERAGGLVLAATPKMKQDHHIK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCEEEEECCCCCCCCCCC
TGSRMYELPTWDKRIIIAPPRMKLYLKVNAMIQAIFKRYVPAEFIHVYSIDECFLDITGS
CCCEEEECCCCCCEEEEECCCEEEEEEHHHHHHHHHHHCCCHHHEEEEEHHHHHHCCCCC
HLLFGSTEEIVRKIQRDILEELRLYVTVGIGDNPLLAKLALDNVAKNRDDGIAEWRYADV
EEEECCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEECCC
PETIWKIRHLDDVCGIGRRTVVRLQKMGIFNMYQLSQTPPPVLKKAMGVIGEQLYYHAHG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHEHHCCCCCHHHHHHHHHHHHHHHHHHCCC
IDYSLLNEKYVPVSKSYGKSQILERDYHASAEVEIVIREMVEEVAMRLRQNHVDTAVIHL
CCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SIGYSKYSIKKGFSHQAKIPSTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTG
EECCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECC
LQLNLFEDTSHTLNQEQLEITVDKIRTRYGFKSLMHASSLLNGATGLKRSEMVGGHKG
CEEEEECCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MRRVVIFYVLILNRFFASVECVKRRLNPLDAYLVVMSNAERAGGLVLAATPKMKQDHHIK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEECCCCCCCEEEEECCCCCCCCCCC
TGSRMYELPTWDKRIIIAPPRMKLYLKVNAMIQAIFKRYVPAEFIHVYSIDECFLDITGS
CCCEEEECCCCCCEEEEECCCEEEEEEHHHHHHHHHHHCCCHHHEEEEEHHHHHHCCCCC
HLLFGSTEEIVRKIQRDILEELRLYVTVGIGDNPLLAKLALDNVAKNRDDGIAEWRYADV
EEEECCHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCEECCC
PETIWKIRHLDDVCGIGRRTVVRLQKMGIFNMYQLSQTPPPVLKKAMGVIGEQLYYHAHG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHEHHCCCCCHHHHHHHHHHHHHHHHHHCCC
IDYSLLNEKYVPVSKSYGKSQILERDYHASAEVEIVIREMVEEVAMRLRQNHVDTAVIHL
CCHHHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SIGYSKYSIKKGFSHQAKIPSTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTG
EECCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECC
LQLNLFEDTSHTLNQEQLEITVDKIRTRYGFKSLMHASSLLNGATGLKRSEMVGGHKG
CEEEEECCCCCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]