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The map label for this gene is aspC [H]

Identifier: 116873684

GI number: 116873684

Start: 2307408

End: 2308559

Strand: Direct

Name: aspC [H]

Synonym: lwe2268

Alternate gene names: 116873684

Gene position: 2307408-2308559 (Clockwise)

Preceding gene: 116873683

Following gene: 116873686

Centisome position: 81.99

GC content: 36.28

Gene sequence:

>1152_bases
ATGATGAGTAACTCAAAAATTGCTAAAAAACATCAACAAATGCCCGTTAACATCCTAGCTGATATCGGAACATTAGCAAA
AACAATGCCTGATATTCTAGATTTATCCATTGGTGATCCCGATTTAATTACAGATGAATCAATCATTAACGCAGCTTTTG
AAGATGTTCGAGCAGGTCATACAAAATACACAGAATCTGGTGGAGATGTTGAGTTAATTGATGCCATCCGAGGTTATTTC
AGTCGTAATTACGAGCTTTCCTTTGAACGTAGTCAAATCCGCGCCACAGTGGGCGCACTCCATGGTATGTATTTAACTTT
ACAAACGATTCTTGACCCTGGTGATGAAGTGATTATTCACGAACCTTACTTCTCCCCTTATAAAGATCAAGTGCTAAATT
CTGGTGGTACGCCAATTATCATTCCTACTTATGAAAAAGATGATTTTGCTATTAATGTAGCTATTTTAGAAGCCGCTATT
ACAAATAAAACCAAAGCATTAATTTTAAACTCGCCTAATAACCCAACTGGCGCTGTTTTCTCACCTGAAACCTTTGAAAA
AATCGCTAATCTTGCAAAAAAATACGATTTCTTCATTTTATCTGACGAGGTGTATGATGGTTTTAGTTTTTATGAACCTT
TCGTTCCTATGGCAAAATTTGCACCAGATCATACTATTACTTTCGGTAGTATGTCTAAAAATTTTGCGATGACTGGATGG
CGCTTAGGTTATATGATTGCTCCCACCTATCTAAACGAAGCTGCCAAAATTATTAACGAAGGAATAACTTATTCAGCTCC
TACACCTTCTCAACGAGCTGCTATTTACGCATTGAATCATTCTGAGACTCTCATTCCTCAAGTAACAGAAACGTTCCAAA
AACGCTTAGAATACATCTCCAAACGTGTAAAAGAAATTCCGTATCTTTCTTTACATCCACTTAAAGGATCGATTTATGCG
TTTATTAATATTTCAAAAACTGGAATGGATTCCGTTTCATTTACGGAATATGTTTTAAAAGAAACACAAGTACTCGTTAT
TCCAGGTTTAGCTTTTGGAGAATCCGGTGATAATTATGCACGATTAGCTGCAACACAAGATATTAGTGTGCTGGAAGAAG
CCTTCAACCGTCTAGCCAAATTAACCTTTTAA

Upstream 100 bases:

>100_bases
GACTTTTTAGGAAAAGTTTTAGCATAAAACATAGATTGCGTCTTACCTGTTACTGGTGAGGCGTTTATCTGCACTTATAG
AAAAAAGGAGCTAATTAAAC

Downstream 100 bases:

>100_bases
TCAAAAAGAGCAAACTCGCTAAATCAGCAAGTTTGCTCTTTTTTAATTTAAATTAATTTCTGCAAAGGAAGAAACAACCG
TTGCTTCTTTTGGAAAAACA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MMSNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGHTKYTESGGDVELIDAIRGYF
SRNYELSFERSQIRATVGALHGMYLTLQTILDPGDEVIIHEPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVAILEAAI
TNKTKALILNSPNNPTGAVFSPETFEKIANLAKKYDFFILSDEVYDGFSFYEPFVPMAKFAPDHTITFGSMSKNFAMTGW
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPQVTETFQKRLEYISKRVKEIPYLSLHPLKGSIYA
FINISKTGMDSVSFTEYVLKETQVLVIPGLAFGESGDNYARLAATQDISVLEEAFNRLAKLTF

Sequences:

>Translated_383_residues
MMSNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGHTKYTESGGDVELIDAIRGYF
SRNYELSFERSQIRATVGALHGMYLTLQTILDPGDEVIIHEPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVAILEAAI
TNKTKALILNSPNNPTGAVFSPETFEKIANLAKKYDFFILSDEVYDGFSFYEPFVPMAKFAPDHTITFGSMSKNFAMTGW
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPQVTETFQKRLEYISKRVKEIPYLSLHPLKGSIYA
FINISKTGMDSVSFTEYVLKETQVLVIPGLAFGESGDNYARLAATQDISVLEEAFNRLAKLTF
>Mature_383_residues
MMSNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGHTKYTESGGDVELIDAIRGYF
SRNYELSFERSQIRATVGALHGMYLTLQTILDPGDEVIIHEPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVAILEAAI
TNKTKALILNSPNNPTGAVFSPETFEKIANLAKKYDFFILSDEVYDGFSFYEPFVPMAKFAPDHTITFGSMSKNFAMTGW
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPQVTETFQKRLEYISKRVKEIPYLSLHPLKGSIYA
FINISKTGMDSVSFTEYVLKETQVLVIPGLAFGESGDNYARLAATQDISVLEEAFNRLAKLTF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=281, Percent_Identity=31.3167259786477, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI56713256, Length=281, Percent_Identity=31.3167259786477, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI95147551, Length=391, Percent_Identity=25.3196930946292, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI169881279, Length=391, Percent_Identity=25.3196930946292, Blast_Score=133, Evalue=3e-31,
Organism=Homo sapiens, GI169881281, Length=300, Percent_Identity=25.3333333333333, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=25.3968253968254, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI19263340, Length=402, Percent_Identity=23.3830845771144, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI215599424, Length=397, Percent_Identity=23.4256926952141, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI149944424, Length=199, Percent_Identity=27.1356783919598, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788722, Length=373, Percent_Identity=29.7587131367292, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1786816, Length=389, Percent_Identity=24.6786632390745, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788627, Length=291, Percent_Identity=26.1168384879725, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1787909, Length=357, Percent_Identity=22.6890756302521, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=396, Percent_Identity=28.2828282828283, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI71994476, Length=396, Percent_Identity=28.2828282828283, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17567369, Length=355, Percent_Identity=30.1408450704225, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17567663, Length=399, Percent_Identity=25.062656641604, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6322401, Length=363, Percent_Identity=28.3746556473829, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=29.0488431876607, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=29.0488431876607, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=29.0488431876607, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=29.0488431876607, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI21356535, Length=398, Percent_Identity=24.3718592964824, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=22.5464190981432, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42572; Mature: 42572

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGH
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
TKYTESGGDVELIDAIRGYFSRNYELSFERSQIRATVGALHGMYLTLQTILDPGDEVIIH
CEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVAILEAAITNKTKALILNSPNNPTGAVF
CCCCCCHHHHHHCCCCCEEEEECCCCCCEEEEEEEEEHHHCCCCEEEEEECCCCCCCCEE
SPETFEKIANLAKKYDFFILSDEVYDGFSFYEPFVPMAKFAPDHTITFGSMSKNFAMTGW
CHHHHHHHHHHHHHCCEEEEEHHHHCCHHHHCCCCCHHHCCCCCEEEECCCCCCEEECCE
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPQVTETFQKRLEYIS
EEEEEECHHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KRVKEIPYLSLHPLKGSIYAFINISKTGMDSVSFTEYVLKETQVLVIPGLAFGESGDNYA
HHHHHCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEECCEEECCCCCCEE
RLAATQDISVLEEAFNRLAKLTF
EEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSNSKIAKKHQQMPVNILADIGTLAKTMPDILDLSIGDPDLITDESIINAAFEDVRAGH
CCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
TKYTESGGDVELIDAIRGYFSRNYELSFERSQIRATVGALHGMYLTLQTILDPGDEVIIH
CEECCCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EPYFSPYKDQVLNSGGTPIIIPTYEKDDFAINVAILEAAITNKTKALILNSPNNPTGAVF
CCCCCCHHHHHHCCCCCEEEEECCCCCCEEEEEEEEEHHHCCCCEEEEEECCCCCCCCEE
SPETFEKIANLAKKYDFFILSDEVYDGFSFYEPFVPMAKFAPDHTITFGSMSKNFAMTGW
CHHHHHHHHHHHHHCCEEEEEHHHHCCHHHHCCCCCHHHCCCCCEEEECCCCCCEEECCE
RLGYMIAPTYLNEAAKIINEGITYSAPTPSQRAAIYALNHSETLIPQVTETFQKRLEYIS
EEEEEECHHHHHHHHHHHHCCCEECCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
KRVKEIPYLSLHPLKGSIYAFINISKTGMDSVSFTEYVLKETQVLVIPGLAFGESGDNYA
HHHHHCCCEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCCEEEEECCEEECCCCCCEE
RLAATQDISVLEEAFNRLAKLTF
EEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]