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The map label for this gene is yhdP [H]

Identifier: 116873665

GI number: 116873665

Start: 2287809

End: 2289113

Strand: Direct

Name: yhdP [H]

Synonym: lwe2249

Alternate gene names: 116873665

Gene position: 2287809-2289113 (Clockwise)

Preceding gene: 116873664

Following gene: 116873667

Centisome position: 81.3

GC content: 36.4

Gene sequence:

>1305_bases
TTGATATTAACCATTAAATTTTTAATTATAGCTTTACTTATTGCTATATCGGCTTTTTTCGTAGCAACGGAATTTGCAAT
TGTTAAAATGCGACCAAGCCGATTGGACCAATTAATAGCAGAGAAAGATAAACGTGCTGTACTCGCTAGATATATTTATA
ACCATTTGAATGCTTATTTGTCCGCTTGTCAGCTCGGAATAACCATCAGCTCTCTTGGACTTGGTTGGTTAGGTGAATCG
ACTGTAGAGGCTGCACTGCATCCATTGTTTAGTTTAATGGAACTTCCGCAATCTGCTATTACGATTCTTTCTTTCACAAT
TGCCTTCCTTTTTATCACATTTTTACATGTGGTTGTTGGGGAACTTGTTCCAAAAACACTTGCGATTGATAAAACAGAAG
CAGTTGCGCTTGCAGTTGCCCGTCCATTGCATATTTTTTATAAAGTGATGTTCCCTTTCATTTGGATTTTAAATGGTTCC
GCGGTTTTTATCGCGCGTCTTTTCGGCTTAGAACCAGCTTCCGAACATGAAATCGCTCATACGGAAGACGAATTAAAAAT
CATTGTTGGCGAAAGTTACAAGAGTGGCGAGATAAACCAGTCAGAATTTCGTTATGTAAATAAAATTTTTGACTTTGATG
AACGTATGGCAAAAGAAGTGATGATTCCACGAACAGAAATTGTCACGGTTGATACAGGTTCTACTATTGGTGAATTATCT
GATATTATGCGAAATGAACGATATACGCGTTATCCAGTCATTGATGGTGACAAAGACCATGTTATTGGTGTACTTAATCT
AAAAGAAATTTTATCAGCCTATGTAGAGCACGGTTCCAATCCAAGCTTTAGTATTGATCCATATGTCAAACCAATTATCC
GTGTTATTGAGACCATTCCAATTAAAGAATTGCTTTTCCGGATGCAGCGTGAACGTTCTCATATTGCGATTCTCCTTGAC
GAATACGGCGGTACTTCTGGACTTGTTACTGTAGAAGATATTGTCGAGGAAATTGTTGGAGATATTCGTGATGAATTTGA
TGCTGATGAAATTCCAGAAATTCGCAAAATCAAAGACGGTCACTACATTGTAGATGCTAAACTTCTTATTGATGAGGTAA
ACAATATTTTAGGAACTGAAATTGAAGAAGAAGAAGTTGATACAATCGGTGGTTGGTTCTTAACACAAAATTATGAAGTA
GAAGTTGGGGACGAAATTGATTACGATGGATTTATTTTCCGCGTTAAACAAGGTGAACCTCATCATATTGAGTATATTGA
AATTATCAAAAAAACGAATGATTAA

Upstream 100 bases:

>100_bases
AGCGGTTTTTCTTCTATATAGATAGTTTTATCATAAGCTTATTTATATTAAATTAGGAGGTGTTTGCCTTCGCAGAAACT
ATTTCTGTCAAGGCGATTTA

Downstream 100 bases:

>100_bases
TAAAAGGCGGCTATCTCAAAAGGATAGCTGCTTTTTAAATACGTTGATTTAACATAAATTGTTTGAATTTTTCTGCTGCC
GGAGTTAAGGTTTGGTTTTT

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MILTIKFLIIALLIAISAFFVATEFAIVKMRPSRLDQLIAEKDKRAVLARYIYNHLNAYLSACQLGITISSLGLGWLGES
TVEAALHPLFSLMELPQSAITILSFTIAFLFITFLHVVVGELVPKTLAIDKTEAVALAVARPLHIFYKVMFPFIWILNGS
AVFIARLFGLEPASEHEIAHTEDELKIIVGESYKSGEINQSEFRYVNKIFDFDERMAKEVMIPRTEIVTVDTGSTIGELS
DIMRNERYTRYPVIDGDKDHVIGVLNLKEILSAYVEHGSNPSFSIDPYVKPIIRVIETIPIKELLFRMQRERSHIAILLD
EYGGTSGLVTVEDIVEEIVGDIRDEFDADEIPEIRKIKDGHYIVDAKLLIDEVNNILGTEIEEEEVDTIGGWFLTQNYEV
EVGDEIDYDGFIFRVKQGEPHHIEYIEIIKKTND

Sequences:

>Translated_434_residues
MILTIKFLIIALLIAISAFFVATEFAIVKMRPSRLDQLIAEKDKRAVLARYIYNHLNAYLSACQLGITISSLGLGWLGES
TVEAALHPLFSLMELPQSAITILSFTIAFLFITFLHVVVGELVPKTLAIDKTEAVALAVARPLHIFYKVMFPFIWILNGS
AVFIARLFGLEPASEHEIAHTEDELKIIVGESYKSGEINQSEFRYVNKIFDFDERMAKEVMIPRTEIVTVDTGSTIGELS
DIMRNERYTRYPVIDGDKDHVIGVLNLKEILSAYVEHGSNPSFSIDPYVKPIIRVIETIPIKELLFRMQRERSHIAILLD
EYGGTSGLVTVEDIVEEIVGDIRDEFDADEIPEIRKIKDGHYIVDAKLLIDEVNNILGTEIEEEEVDTIGGWFLTQNYEV
EVGDEIDYDGFIFRVKQGEPHHIEYIEIIKKTND
>Mature_434_residues
MILTIKFLIIALLIAISAFFVATEFAIVKMRPSRLDQLIAEKDKRAVLARYIYNHLNAYLSACQLGITISSLGLGWLGES
TVEAALHPLFSLMELPQSAITILSFTIAFLFITFLHVVVGELVPKTLAIDKTEAVALAVARPLHIFYKVMFPFIWILNGS
AVFIARLFGLEPASEHEIAHTEDELKIIVGESYKSGEINQSEFRYVNKIFDFDERMAKEVMIPRTEIVTVDTGSTIGELS
DIMRNERYTRYPVIDGDKDHVIGVLNLKEILSAYVEHGSNPSFSIDPYVKPIIRVIETIPIKELLFRMQRERSHIAILLD
EYGGTSGLVTVEDIVEEIVGDIRDEFDADEIPEIRKIKDGHYIVDAKLLIDEVNNILGTEIEEEEVDTIGGWFLTQNYEV
EVGDEIDYDGFIFRVKQGEPHHIEYIEIIKKTND

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=399, Percent_Identity=47.1177944862155, Blast_Score=398, Evalue=1e-111,
Organism=Escherichia coli, GI1790664, Length=431, Percent_Identity=23.2018561484919, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1786879, Length=264, Percent_Identity=31.4393939393939, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI145693175, Length=386, Percent_Identity=22.279792746114, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI87082033, Length=243, Percent_Identity=23.8683127572016, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788119, Length=239, Percent_Identity=27.6150627615063, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49181; Mature: 49181

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00024 HEMOPEXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILTIKFLIIALLIAISAFFVATEFAIVKMRPSRLDQLIAEKDKRAVLARYIYNHLNAYL
CEEEHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SACQLGITISSLGLGWLGESTVEAALHPLFSLMELPQSAITILSFTIAFLFITFLHVVVG
HHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELVPKTLAIDKTEAVALAVARPLHIFYKVMFPFIWILNGSAVFIARLFGLEPASEHEIAH
HHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
TEDELKIIVGESYKSGEINQSEFRYVNKIFDFDERMAKEVMIPRTEIVTVDTGSTIGELS
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
DIMRNERYTRYPVIDGDKDHVIGVLNLKEILSAYVEHGSNPSFSIDPYVKPIIRVIETIP
HHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
IKELLFRMQRERSHIAILLDEYGGTSGLVTVEDIVEEIVGDIRDEFDADEIPEIRKIKDG
HHHHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
HYIVDAKLLIDEVNNILGTEIEEEEVDTIGGWFLTQNYEVEVGDEIDYDGFIFRVKQGEP
CEEEEHHHHHHHHHHHHCCCCCHHHHHHHCCEEEECCEEEEECCCCCCCCEEEEEECCCC
HHIEYIEIIKKTND
CCHHHHHHHHHCCC
>Mature Secondary Structure
MILTIKFLIIALLIAISAFFVATEFAIVKMRPSRLDQLIAEKDKRAVLARYIYNHLNAYL
CEEEHHHHHHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SACQLGITISSLGLGWLGESTVEAALHPLFSLMELPQSAITILSFTIAFLFITFLHVVVG
HHHHHCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
ELVPKTLAIDKTEAVALAVARPLHIFYKVMFPFIWILNGSAVFIARLFGLEPASEHEIAH
HHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCC
TEDELKIIVGESYKSGEINQSEFRYVNKIFDFDERMAKEVMIPRTEIVTVDTGSTIGELS
CCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHH
DIMRNERYTRYPVIDGDKDHVIGVLNLKEILSAYVEHGSNPSFSIDPYVKPIIRVIETIP
HHHHCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCC
IKELLFRMQRERSHIAILLDEYGGTSGLVTVEDIVEEIVGDIRDEFDADEIPEIRKIKDG
HHHHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
HYIVDAKLLIDEVNNILGTEIEEEEVDTIGGWFLTQNYEVEVGDEIDYDGFIFRVKQGEP
CEEEEHHHHHHHHHHHHCCCCCHHHHHHHCCEEEECCEEEEECCCCCCCCEEEEEECCCC
HHIEYIEIIKKTND
CCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]