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The map label for this gene is ahpF [C]

Identifier: 116873403

GI number: 116873403

Start: 2015049

End: 2016047

Strand: Direct

Name: ahpF [C]

Synonym: lwe1987

Alternate gene names: 116873403

Gene position: 2015049-2016047 (Clockwise)

Preceding gene: 116873402

Following gene: 116873408

Centisome position: 71.6

GC content: 38.64

Gene sequence:

>999_bases
TTGCCAAATGAAGTATATGATGTCACCATTATTGGCGGCGGTCCAATTGGACTTTTTTCCGCATTTTATAGTGGCCTACG
TTCAATGAAAACTAAAATAATTGATGCGGAACCAGCTGTTGGTGGCAAAGTCCGTTACTTTTTTCCCGAAAAAATTATTC
GCGACATTGGTGGTATTCCAGCTATTACTGGTGAAAATCTTGTTGCAAATTTAAAAGAACAAGCCGAGACGTTCCATCCA
ACTATTGTTTGTAATGAGCGTGTAGTGGATGTGACTAGATTAACGGATGGTACTTTTCAATTAATCACTCATAATGGTTC
CATCCATTTTTCTAAAACAATTGTTATCGCAACAGGTAGTGGAACTTTTGAAGTAAATAAACTGGAAGCATTACATGTGG
AGGATTTTCCACTAGCGATTCATTACGATGTGAAAAATATCGAGCAATTTCGAGATAAAGTTGTTGCCGTTTCCGGTGGA
GGAAATTCAGCTATTGACTGGGCCCAAACACTTGAGCCAATCGCTAAACAAGTACATCTTATTTATCGCGGAGAAGATTT
TAAAGCACATGAAGAAAGCGTTCGTGAACTTAAAAACTCTCGCGTCAAAATTCATATTCACCATGAAATCCATGAATTAT
TTGGAACGAACAACCAGCTAGCTGAAATAAGTGTTATTTGCAATCAAACACAAGCTACTAAAACTATTGAAACAGAAGCA
CTCTTCATTAATCATGGAGTGAAAGTAGATCTTGGAACGATGGCTGAGTGGGGATTCGAACAAGCTGATTTTGGTATCGT
TGTAGATGATGAAATGAAAACGACTGTCCCTGGCATTTTTGCTTGTGGAGATAGCGCCACATATCCTCGAAAACTTCGCA
TTATTGCAGCTGGATTACATGAAGGGCCGATTGCGATTAATAGCGCAAAAAAATATTTAGAACCAACTGCTGCTGATGAA
GCAATGATCAGCACTCACCACGAAAGCTTTATTGGTTAA

Upstream 100 bases:

>100_bases
ATCAAAGCAGATATTTTGATTGATCCACGCAGCGGCGTCCCTCTTTGTCTCCCGTACGAAACTTGTAATGGATGCGAAAT
TGTAAAGGAGCTTGATTCCA

Downstream 100 bases:

>100_bases
AAAAAGGATTTGGGCTCACTCGCCCAAATCCTTTTTTTCATCACATATACCAAATTCAACAATTCGCATCATTTCCGTAA
ATTCATTCGCAAGCGGAATA

Product: pyridine nucleotide-disulfide oxidoreductase family protein

Products: NA

Alternate protein names: FNR 1; Fd-NADP+ reductase 1 [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKEQAETFHP
TIVCNERVVDVTRLTDGTFQLITHNGSIHFSKTIVIATGSGTFEVNKLEALHVEDFPLAIHYDVKNIEQFRDKVVAVSGG
GNSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELKNSRVKIHIHHEIHELFGTNNQLAEISVICNQTQATKTIETEA
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKLRIIAAGLHEGPIAINSAKKYLEPTAADE
AMISTHHESFIG

Sequences:

>Translated_332_residues
MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKEQAETFHP
TIVCNERVVDVTRLTDGTFQLITHNGSIHFSKTIVIATGSGTFEVNKLEALHVEDFPLAIHYDVKNIEQFRDKVVAVSGG
GNSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELKNSRVKIHIHHEIHELFGTNNQLAEISVICNQTQATKTIETEA
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKLRIIAAGLHEGPIAINSAKKYLEPTAADE
AMISTHHESFIG
>Mature_331_residues
PNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIPAITGENLVANLKEQAETFHPT
IVCNERVVDVTRLTDGTFQLITHNGSIHFSKTIVIATGSGTFEVNKLEALHVEDFPLAIHYDVKNIEQFRDKVVAVSGGG
NSAIDWAQTLEPIAKQVHLIYRGEDFKAHEESVRELKNSRVKIHIHHEIHELFGTNNQLAEISVICNQTQATKTIETEAL
FINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKLRIIAAGLHEGPIAINSAKKYLEPTAADEA
MISTHHESFIG

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI87081763, Length=324, Percent_Identity=26.8518518518519, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787114, Length=323, Percent_Identity=26.625386996904, Blast_Score=75, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6321898, Length=331, Percent_Identity=25.6797583081571, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR022890
- InterPro:   IPR001327
- InterPro:   IPR000103 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 36493; Mature: 36362

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIP
CCCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECHHHHHHHCCCCC
AITGENLVANLKEQAETFHPTIVCNERVVDVTRLTDGTFQLITHNGSIHFSKTIVIATGS
CCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCEEEEEEECCEEEEEEEEEEEECC
GTFEVNKLEALHVEDFPLAIHYDVKNIEQFRDKVVAVSGGGNSAIDWAQTLEPIAKQVHL
CEEEEEEEEEEEECCCCEEEEECHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEEE
IYRGEDFKAHEESVRELKNSRVKIHIHHEIHELFGTNNQLAEISVICNQTQATKTIETEA
EEECCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEE
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKLRIIAAGLH
EEEECCCEEEECCHHHCCCCCCCCCEEECCCCCCCCCEEEECCCCCCCCEEEEEEEECCC
EGPIAINSAKKYLEPTAADEAMISTHHESFIG
CCCEEECCHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PNEVYDVTIIGGGPIGLFSAFYSGLRSMKTKIIDAEPAVGGKVRYFFPEKIIRDIGGIP
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEEECHHHHHHHCCCCC
AITGENLVANLKEQAETFHPTIVCNERVVDVTRLTDGTFQLITHNGSIHFSKTIVIATGS
CCCCCHHHHHHHHHHHHCCCEEEECCCEEEEEEECCCEEEEEEECCEEEEEEEEEEEECC
GTFEVNKLEALHVEDFPLAIHYDVKNIEQFRDKVVAVSGGGNSAIDWAQTLEPIAKQVHL
CEEEEEEEEEEEECCCCEEEEECHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHEEE
IYRGEDFKAHEESVRELKNSRVKIHIHHEIHELFGTNNQLAEISVICNQTQATKTIETEA
EEECCCCCHHHHHHHHHHCCEEEEEEEHHHHHHHCCCCCEEEEEEEECCCCCCCEEEEEE
LFINHGVKVDLGTMAEWGFEQADFGIVVDDEMKTTVPGIFACGDSATYPRKLRIIAAGLH
EEEECCCEEEECCHHHCCCCCCCCCEEECCCCCCCCCEEEECCCCCCCCEEEEEEEECCC
EGPIAINSAKKYLEPTAADEAMISTHHESFIG
CCCEEECCHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]