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The map label for this gene is ppnK [H]

Identifier: 116873015

GI number: 116873015

Start: 1605237

End: 1606040

Strand: Direct

Name: ppnK [H]

Synonym: lwe1599

Alternate gene names: 116873015

Gene position: 1605237-1606040 (Clockwise)

Preceding gene: 116873009

Following gene: 116873024

Centisome position: 57.04

GC content: 34.08

Gene sequence:

>804_bases
ATGGCAAAAACTATTTTTTATTTTTCCTATCGAAAAACAGAAGAACTACATGCAAAAGCAAAAGAACTAAAGAAAATTAC
GACTGATTATGGTTATGAATTAACTGATGACTATCAAAAAGCAAACGTTATTATCAGTATTGGTGGTGATGGTGCTTTTC
TTAAATCCGTAAGAGAAACCGGCTTCCGTCAAGATTGTTTATATGCAGGAATTGCGCTAACAGAACAATTAGGTCAGTAT
TGCGATTTCCATATTAATCAATTGGATGAAATCATTAAAGCTGCCATTGAAGATCGTTGGTTAGTTCGTCGTTATCCAAC
TATTTACGGTACAGTAAATAATACTAAAGCTTTTTATGTGTTGAATGAATTTAATATTCGTTCTTCTATTATCAGAACCC
TGACAATAGATCTTTATATTAATGATTCTCACTTTGAGACGTTCCGAGGCGATGGAATGGTTATCTCCACACCAACAGGA
AGTACAGCTTATAATAAATCTGTAAATGGTTCTATCGTGGATCCACTTCTTCCATCTATGCAAGTAAGTGAACTAGCTTC
TATTAACAATAACAAATTCCGTACACTAGGGTCTTCTTTCATTCTTAGTCCAAAACGTAAACTACGTATTGAGATTGCGT
CTGAAGAAGGGAATAATGAGTTCCCAATGATTGGAATGGACAGTGAAGCACTTAGCATTCAACATGTTCATGAGGTAAAC
CTAGAAGTAGGCGATCGTTTTATCAATATTATCAAACTTCCGAAAAATTCTTTCTGGGATAAAGTTAAGCGTAATTTCTT
ATAA

Upstream 100 bases:

>100_bases
GTCCCATTTCACTTTTTTACTAGATGAAGAAAGAAATTGCTTCTAAGTCATGTTATAATAAGTTTGTTGATTAAAATTGG
ATTCTGGAGGGACAACTAAC

Downstream 100 bases:

>100_bases
TAAAAAGAGTCTGGCGTAGCTGCCAGACTCTTTTTATTTTGCTTCCAAAATAGCTGCTAGTAATGCTTTTTGTGCGTGAA
GTCTATTTCCTGCTTGTTGA

Product: inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase 2 [H]

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MAKTIFYFSYRKTEELHAKAKELKKITTDYGYELTDDYQKANVIISIGGDGAFLKSVRETGFRQDCLYAGIALTEQLGQY
CDFHINQLDEIIKAAIEDRWLVRRYPTIYGTVNNTKAFYVLNEFNIRSSIIRTLTIDLYINDSHFETFRGDGMVISTPTG
STAYNKSVNGSIVDPLLPSMQVSELASINNNKFRTLGSSFILSPKRKLRIEIASEEGNNEFPMIGMDSEALSIQHVHEVN
LEVGDRFINIIKLPKNSFWDKVKRNFL

Sequences:

>Translated_267_residues
MAKTIFYFSYRKTEELHAKAKELKKITTDYGYELTDDYQKANVIISIGGDGAFLKSVRETGFRQDCLYAGIALTEQLGQY
CDFHINQLDEIIKAAIEDRWLVRRYPTIYGTVNNTKAFYVLNEFNIRSSIIRTLTIDLYINDSHFETFRGDGMVISTPTG
STAYNKSVNGSIVDPLLPSMQVSELASINNNKFRTLGSSFILSPKRKLRIEIASEEGNNEFPMIGMDSEALSIQHVHEVN
LEVGDRFINIIKLPKNSFWDKVKRNFL
>Mature_266_residues
AKTIFYFSYRKTEELHAKAKELKKITTDYGYELTDDYQKANVIISIGGDGAFLKSVRETGFRQDCLYAGIALTEQLGQYC
DFHINQLDEIIKAAIEDRWLVRRYPTIYGTVNNTKAFYVLNEFNIRSSIIRTLTIDLYINDSHFETFRGDGMVISTPTGS
TAYNKSVNGSIVDPLLPSMQVSELASINNNKFRTLGSSFILSPKRKLRIEIASEEGNNEFPMIGMDSEALSIQHVHEVNL
EVGDRFINIIKLPKNSFWDKVKRNFL

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325068, Length=216, Percent_Identity=26.3888888888889, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 30481; Mature: 30350

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTIFYFSYRKTEELHAKAKELKKITTDYGYELTDDYQKANVIISIGGDGAFLKSVRET
CCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEECCCHHHHHHHHHC
GFRQDCLYAGIALTEQLGQYCDFHINQLDEIIKAAIEDRWLVRRYPTIYGTVNNTKAFYV
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCEEEEE
LNEFNIRSSIIRTLTIDLYINDSHFETFRGDGMVISTPTGSTAYNKSVNGSIVDPLLPSM
EEECCHHHHEEEEEEEEEEEECCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCH
QVSELASINNNKFRTLGSSFILSPKRKLRIEIASEEGNNEFPMIGMDSEALSIQHVHEVN
HHHHHHHCCCCCEEECCCCEEECCCEEEEEEEECCCCCCCCCEEECCCCHHEEEHHEECC
LEVGDRFINIIKLPKNSFWDKVKRNFL
HHHCCEEEEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure 
AKTIFYFSYRKTEELHAKAKELKKITTDYGYELTDDYQKANVIISIGGDGAFLKSVRET
CCEEEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEEEECCCHHHHHHHHHC
GFRQDCLYAGIALTEQLGQYCDFHINQLDEIIKAAIEDRWLVRRYPTIYGTVNNTKAFYV
CCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEECCEEEEEECCCEEEEE
LNEFNIRSSIIRTLTIDLYINDSHFETFRGDGMVISTPTGSTAYNKSVNGSIVDPLLPSM
EEECCHHHHEEEEEEEEEEEECCCCEEECCCCEEEECCCCCCCCCCCCCCCCCCCCCCCH
QVSELASINNNKFRTLGSSFILSPKRKLRIEIASEEGNNEFPMIGMDSEALSIQHVHEVN
HHHHHHHCCCCCEEECCCCEEECCCEEEEEEEECCCCCCCCCEEECCCCHHEEEHHEECC
LEVGDRFINIIKLPKNSFWDKVKRNFL
HHHCCEEEEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]