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The map label for this gene is yclJ [H]

Identifier: 116872936

GI number: 116872936

Start: 1515236

End: 1515922

Strand: Direct

Name: yclJ [H]

Synonym: lwe1520

Alternate gene names: 116872936

Gene position: 1515236-1515922 (Clockwise)

Preceding gene: 116872929

Following gene: 116872937

Centisome position: 53.84

GC content: 34.5

Gene sequence:

>687_bases
ATGAAACTACTGATGATAGAAGATAATGTGAGTGTTTGTGAAATGATAGAAATGTTCTTTATGAAAGAAGAAATTGATGC
AACGTTTGTGCACGATGGCAAACTTGGCTTTGAAACATTTTTTAAAGATGATTTTGATATTGCGATTATTGATTTAATGT
TGCCAAATATGGATGGCATGACTATTTGCAGGAAAATACGTGAAGTCAGCGATGTTCCTATCATTATTTTAACAGCGAAA
GAATCAGAATCAGACCAGGTACTTGGACTTGAAATGGGTGCGGATGATTATGTAACAAAACCATTTAGCCCACTTACTTT
AATGGCTCGAATCAAAGCTGTCACTCGTCGGAAAAATAATAGTTCTTCCAATGAAAACGAGGAAGATATTTTAGAAACAA
ACTATTTTAAAATCAGTAAACGTACTCGCGAAATTTTTTATCAAGGAAAGCTTTTAGATGCTTTAACACCAAAAGAATTT
GATTTACTTTACTTTTTAATGCAGCATCCACGTCAAGTTTTTTCAAGAGAACAATTACTGGAGCAAGTTTGGGGTTATCA
ATTTTATGGAGATGAGCGTACTGTGGATGTTCATATTAAACGTTTACGCCAAAAAATTGCCACAGATACGAAGCCGTTTT
TACACACTGTTTGGGGTGTGGGCTACAAATTTGATGAAACGGAATGA

Upstream 100 bases:

>100_bases
AACTATGATGCATATTTTAAACTTTCGCGAAAAAAATAATTTGGCTTGATTATTGGGTCTAATTAGTCTAATTTTAATGT
AAGAGGAGTGAATACAAATT

Downstream 100 bases:

>100_bases
AGCGAATGAAATTTAAATATGCTTATCAACTTTTTTTCACACAATTTATCATCTTGCTCATTGCTTGTATTATGATTGGG
GTGTTAGTCTCCCATTCATT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKLGFETFFKDDFDIAIIDLMLPNMDGMTICRKIREVSDVPIIILTAK
ESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNNSSSNENEEDILETNYFKISKRTREIFYQGKLLDALTPKEF
DLLYFLMQHPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRQKIATDTKPFLHTVWGVGYKFDETE

Sequences:

>Translated_228_residues
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKLGFETFFKDDFDIAIIDLMLPNMDGMTICRKIREVSDVPIIILTAK
ESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNNSSSNENEEDILETNYFKISKRTREIFYQGKLLDALTPKEF
DLLYFLMQHPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRQKIATDTKPFLHTVWGVGYKFDETE
>Mature_228_residues
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKLGFETFFKDDFDIAIIDLMLPNMDGMTICRKIREVSDVPIIILTAK
ESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNNSSSNENEEDILETNYFKISKRTREIFYQGKLLDALTPKEF
DLLYFLMQHPRQVFSREQLLEQVWGYQFYGDERTVDVHIKRLRQKIATDTKPFLHTVWGVGYKFDETE

Specific function: Could be member of the two-component regulatory system yclK/yclJ [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=37.280701754386, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1788394, Length=230, Percent_Identity=36.5217391304348, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=36.5638766519824, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=35.0877192982456, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=34.5132743362832, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.8017621145374, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=35.3191489361702, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.9559471365639, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=33.4821428571429, Blast_Score=119, Evalue=1e-28,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=30.672268907563, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.0043668122271, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1786911, Length=181, Percent_Identity=34.2541436464088, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=32.4561403508772, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=29.1479820627803, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26755; Mature: 26755

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKLGFETFFKDDFDIAIIDLMLPNMDGM
CEEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHCCCCCCEEEEEEECCCCCHH
TICRKIREVSDVPIIILTAKESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNN
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
SSSNENEEDILETNYFKISKRTREIFYQGKLLDALTPKEFDLLYFLMQHPRQVFSREQLL
CCCCCCHHHHHHCCCEEHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EQVWGYQFYGDERTVDVHIKRLRQKIATDTKPFLHTVWGVGYKFDETE
HHHHCEEEECCCEEEHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCC
>Mature Secondary Structure
MKLLMIEDNVSVCEMIEMFFMKEEIDATFVHDGKLGFETFFKDDFDIAIIDLMLPNMDGM
CEEEEEECCCHHHHHHHHHHHHHHCCEEEEECCCCCHHHHCCCCCCEEEEEEECCCCCHH
TICRKIREVSDVPIIILTAKESESDQVLGLEMGADDYVTKPFSPLTLMARIKAVTRRKNN
HHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCC
SSSNENEEDILETNYFKISKRTREIFYQGKLLDALTPKEFDLLYFLMQHPRQVFSREQLL
CCCCCCHHHHHHCCCEEHHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
EQVWGYQFYGDERTVDVHIKRLRQKIATDTKPFLHTVWGVGYKFDETE
HHHHCEEEECCCEEEHHHHHHHHHHHCCCCCHHHHHHHCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]