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The map label for this gene is 116872831

Identifier: 116872831

GI number: 116872831

Start: 1405825

End: 1407387

Strand: Direct

Name: 116872831

Synonym: lwe1415

Alternate gene names: NA

Gene position: 1405825-1407387 (Clockwise)

Preceding gene: 116872830

Following gene: 116872832

Centisome position: 49.96

GC content: 40.56

Gene sequence:

>1563_bases
ATGACAATCGCAATCACGATCATCTCCAGTTTGCTTTTCTTAATCGTCGGTCTAGTTGTTGGTTCTCTAATTTTTAAATC
TAGTACAGAGAAAAAACTGGCTGCTGCAAGGGGGACTGCTGAATTAATTGTAGAAGATGCCAAGAAAGAAGCAGAAACTA
CAAAAAAAGAAGCATTGCTTGAAGCGAAGGAAGAGAATCATAGGTTACGTACTGAAATCGAAAATGAACTTCGTGGGCGA
AGAACAGAGACACAGAAAGCAGAAAATCGCTTATTGCAAAGGGAGGAAAACCTCGACCGTAAAGATACTTCTTTAAGTAA
ACGAGAAGCTACACTTGAAAGAAAAGAGGAGAGTATCAGTAAACGTCAACAACAAATTGAAGAGAAAGAAAGCAAACTAG
CTGAGATGATTCAAGCGGAGCAGACAGAACTTGAAAGAATTTCTGCGCTCAGCAAAGAAGAAGCGAAATCTATCATCCTT
AACCAGGTAGAAGATGAATTAACACATGATACTGCAATCATGGTCAAAGAAACAGAAAACCGGGCCAAGGAAGAGTCGGA
TAAAAAAGCAAAGAATATTCTCTCACTAGCTATCCAGCGTTGTGCAGCTGATCATGTGGCAGAAACAACAGTATCTGTTG
TTACCTTACCAAATGATGAGATGAAAGGACGAATTATCGGACGTGAAGGCCGTAATATTCGTACGCTAGAAACGCTTACA
GGGATTGACTTGATAATTGATGATACACCGGAAGCAGTTATTCTTTCCGGATTTGATCCAATTCGACGTGAAATCGCTAG
AATCGCCTTAGAAAAACTTGTTCAAGATGGACGAATCCATCCTGCTCGAATTGAAGAAATGGTGGACAAAGCCCGTAAAG
AGGTTGATGAACACATTCGTGAAGTCGGGGAACAAGCAACATTTGAAGTTGGAATTCACTCCATCCATCCTGATTTGATA
AAAATTCTTGGCCGCTTGCGTTATCGTACTAGTTACGGACAAAACGTTCTTAACCACTCACTCGAAGTTTCGAAACTTGC
TGGTATTTTGGCAGGAGAGCTTGGCGAAGACGTTACGCTTGCTAAACGGGCCGGACTACTTCATGACATTGGTAAAGCAA
TTGACCATGAAATTGAAGGAAGTCACGTTGAAATCGGCGTGGAACTTGCTACTAAATACAAAGAAAATGATGTGGTAATC
AACAGTATTGCTTCCCATCATGGAGATACAGAAGCTACTTCTGTTATCGCAGTATTGGTTGCAGCAGCGGATGCACTTTC
TGCTGCAAGACCAGGAGCTCGTAGTGAAACGCTTGAAAATTACATTCGTCGTTTAGAAAAATTAGAAGAAATTTCTGAGT
CTTATGATGGTGTAGAAAAATCTTATGCAATCCAAGCAGGGCGTGAAGTACGTATCATCGTTGAACCAGATACAATTGAT
GATCTTTCTTCTTACCGACTTGCTCGCGACATAAGAAAACGAATTGAAGAGGAATTAGATTACCCTGGTCATATCAAAGT
GACTGTAATTCGTGAAACAAGAGCAGTAGAATACGCTAAATAG

Upstream 100 bases:

>100_bases
AGATTAGCGCTCGGTTGTTGATGAAAAATACGCATGTGCCAGATAATTCTGGCCACCGACATAACAATAACGAAAATTGA
ATAGCAAAGGAGGTGTAAGG

Downstream 100 bases:

>100_bases
TAATATAAAGGTACATCGCGAATTTATTTTGCGGTGTATCTTTTTTTAATCGTTTGCCTAGCTTGAATAAGAACGGTATA
ATTATAAGATAAACAAAATA

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGR
RTETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIIL
NQVEDELTHDTAIMVKETENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLI
KILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVI
NSIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK

Sequences:

>Translated_520_residues
MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGR
RTETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIIL
NQVEDELTHDTAIMVKETENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLI
KILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVI
NSIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
>Mature_519_residues
TIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALLEAKEENHRLRTEIENELRGRR
TETQKAENRLLQREENLDRKDTSLSKREATLERKEESISKRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILN
QVEDELTHDTAIMVKETENRAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTG
IDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIREVGEQATFEVGIHSIHPDLIK
ILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTLAKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVIN
SIASHHGDTEATSVIAVLVAAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTIDD
LSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 58319; Mature: 58188

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALL
CEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EAKEENHRLRTEIENELRGRRTETQKAENRLLQREENLDRKDTSLSKREATLERKEESIS
HHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHH
KRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILNQVEDELTHDTAIMVKETEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
RAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEECCCCCCEEHHHHHC
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIR
CCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVGEQATFEVGIHSIHPDLIKILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVINSIASHHGDTEATSVIAVLV
HHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
AAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCH
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
TIAITIISSLLFLIVGLVVGSLIFKSSTEKKLAAARGTAELIVEDAKKEAETTKKEALL
EEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EAKEENHRLRTEIENELRGRRTETQKAENRLLQREENLDRKDTSLSKREATLERKEESIS
HHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHHH
KRQQQIEEKESKLAEMIQAEQTELERISALSKEEAKSIILNQVEDELTHDTAIMVKETEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHH
RAKEESDKKAKNILSLAIQRCAADHVAETTVSVVTLPNDEMKGRIIGREGRNIRTLETLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCEECCCCCCEEHHHHHC
GIDLIIDDTPEAVILSGFDPIRREIARIALEKLVQDGRIHPARIEEMVDKARKEVDEHIR
CCEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
EVGEQATFEVGIHSIHPDLIKILGRLRYRTSYGQNVLNHSLEVSKLAGILAGELGEDVTL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
AKRAGLLHDIGKAIDHEIEGSHVEIGVELATKYKENDVVINSIASHHGDTEATSVIAVLV
HHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHH
AAADALSAARPGARSETLENYIRRLEKLEEISESYDGVEKSYAIQAGREVRIIVEPDTID
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEECCCCCH
DLSSYRLARDIRKRIEEELDYPGHIKVTVIRETRAVEYAK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]