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The map label for this gene is frr [H]

Identifier: 116872745

GI number: 116872745

Start: 1319160

End: 1319717

Strand: Direct

Name: frr [H]

Synonym: lwe1329

Alternate gene names: 116872745

Gene position: 1319160-1319717 (Clockwise)

Preceding gene: 116872744

Following gene: 116872746

Centisome position: 46.88

GC content: 34.77

Gene sequence:

>558_bases
ATGAGTAAAGAAGTATTAACTAAATCCAAAGAAAAAATGGACAAAGCAGAACAAGCATTAACTAGACAATTAGGTACAAT
TCGTGCTGGACGTGCGAATGCATCACTACTTGATCGTTTATCTGTAGACTATTACGGAGCGCCTACACCAGTTAATCAAA
TGGCTTCTATTAGTGTGCCGGAAGCTAGAATGTTGCTTATTACACCTTATGATAAAACTGTTTTAGGTGAAATTGAAAAA
GCAATTTTGAAATCTGATTTGGGATTAACACCAAATAATGATGGATCTGTACTACGTTTATCTATTCCACAATTAACGGA
AGAACGTCGTAAAGAACTAGTAAAAGAAGTGAAAAAAGAAGCAGAAGAAGCGAAAGTAGCTGTTCGTAATATTCGTCGTG
AAGCAAACGAAGAACTGAAAAAATTAGAAAAAAATGGCGATATTACAGAAGATGATTTGCGTTCTTATGGGGAAGACGTT
CAAAAATTAACGGATGAAAGCATCAAGAACATTGATAACATCACGAAAGACAAAGAAGCGGAAATCTTAGAAGTTTAA

Upstream 100 bases:

>100_bases
ACATTCCATTAATCGTCTTCTCGTTTACAGAACAAGGCAATAATATTAAACGTGTTATTTTAGGAGAAAAAATTGGAACT
ACTGTTAGGGGGAAAAAATA

Downstream 100 bases:

>100_bases
TTGGTACTTTTCAAATAGTAACAAATAAGGTTAATAACCTTTTAAGTTGAAATGACATTCCTAATTCTTTCCATATGTGT
TGGGTTAGGAATGTTTTTTA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MSKEVLTKSKEKMDKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAPTPVNQMASISVPEARMLLITPYDKTVLGEIEK
AILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDV
QKLTDESIKNIDNITKDKEAEILEV

Sequences:

>Translated_185_residues
MSKEVLTKSKEKMDKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAPTPVNQMASISVPEARMLLITPYDKTVLGEIEK
AILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDV
QKLTDESIKNIDNITKDKEAEILEV
>Mature_184_residues
SKEVLTKSKEKMDKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAPTPVNQMASISVPEARMLLITPYDKTVLGEIEKA
ILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKEAEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQ
KLTDESIKNIDNITKDKEAEILEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI291042689, Length=150, Percent_Identity=28.6666666666667, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1786368, Length=174, Percent_Identity=51.7241379310345, Blast_Score=182, Evalue=2e-47,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20795; Mature: 20664

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEVLTKSKEKMDKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAPTPVNQMASISVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHCCCC
EARMLLITPYDKTVLGEIEKAILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKE
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQKLTDESIKNIDNITKDKEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EILEV
HHCCC
>Mature Secondary Structure 
SKEVLTKSKEKMDKAEQALTRQLGTIRAGRANASLLDRLSVDYYGAPTPVNQMASISVP
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCHHHHHHCCCC
EARMLLITPYDKTVLGEIEKAILKSDLGLTPNNDGSVLRLSIPQLTEERRKELVKEVKKE
CCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHH
AEEAKVAVRNIRREANEELKKLEKNGDITEDDLRSYGEDVQKLTDESIKNIDNITKDKEA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EILEV
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]