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The map label for this gene is glpD [H]

Identifier: 116872724

GI number: 116872724

Start: 1299492

End: 1301168

Strand: Direct

Name: glpD [H]

Synonym: lwe1308

Alternate gene names: 116872724

Gene position: 1299492-1301168 (Clockwise)

Preceding gene: 116872723

Following gene: 116872725

Centisome position: 46.18

GC content: 36.91

Gene sequence:

>1677_bases
ATGGTACAATTATTTTCAGCATTTGATAGAGAAACAATTGAAAGAAATCTTCAAGAAGAAAAATTCGATTTAGTCATCGT
TGGCGGAGGAATTACTGGTGCGGGAATCGCATTAGATGCAACTACTAGAGGAATGAATGTTGCATTAGTAGAAATGGGTG
ACTTCGCAAGCGGAACATCCAGCCGTTCAACCAAATTAGTTCATGGTGGTCTACGTTATTTACAACAATTTGAAATCAAA
GAAGTAGCAGATTTAGGGAAAGAACGTGCGATTGTATATGAAAATGGACCGCACGTAACAACACCTGAATGGATGATGCT
CCCATTCCATAAAGGTGGGAACATGGGTAAAACAACCGCTTCATTCGGAATACGTTTGTATGATTATCTTGCAGGCGTGA
AGAAAAATGAACGTCGTAAAATCCTAAGCGCAAAAGAAACATTAGCAAAAAACCCTTTTGTAAAAAAAGATGGTCTGAAG
GGTTCAGGCTATTATGTAGAATACCGGACAGACGATGCTCGTTTAACAATCGAAGTCATGAAAAAAGCGGTAGAACTAGG
AGCAAATGCAATCAATTATACGAAAGCAGAACACTTTTTATATGATGATAATAAACAAGTGGTAGGTGTTACAGTTACCG
ATCGTTTAACAGGAAAAGCTTACGATATTAAAGGTCACCGTGTTATTAATGCAGCTGGTCCTTGGGTAGATAAAGTAAGA
AAATTAGACTATGCGACAAATAATAAACACCTTCGTTTAACTAAAGGAATTCACTTAGTTATTGATAAGAAAAAATTCCC
AATGGAACAAGCTGTTTATTTTGATACTCCAGATGGAAGAATGGTATTCGCAATTCCACGTGATAAAAAAGTCTATGTTG
GAACCACAGATACAGTTTATGATGAAGCAGTAATTAATCCAAAAGCGCTTGAGTCTGATCATAATTATGTAATTAAAGCA
ATTAACTACATGTTCCCAGATGTGCATATTACTGAAAAAGATATTGAATCAAGCTGGGCAGGGGTTCGTCCATTAATTTA
CGAAGAAGGTAAAGATCCATCTGAAATTTCACGAAAAGATGAAGTTTGGTTCTCAGAAAGTGGCTTAATAACAATGGCAG
GTGGGAAACTAACTGGTTACCGTAAAATGGCTGAAAAATTACTTGATGATGTTTCCAAAACGTTGACAAAAGAAACAGGC
AAAAAATATAAACCAGTTCAAACGAAACATTTACCAATTTCGGGAGGAGATATTGGAGGCTCAGAACAACTTGAATCTTT
CCTTTCCAAAAAAGCGAAAGAAGGAAATAATCGTTTCGGTTGGACATTAGAAGAGGGCCGTGAAATCGCCAAACGTTATG
GTAGCAATATTGATCAATTGTTTACTTATGCGCAGGAACATAAAGAACAAGAGGAATCGACTCTACCAAACAGCTTATAT
GCGGAATTACGTTATTCTATTCAGCACGAAGCTGTTACAACGCCAATTGACTTTTTACTTCGTCGGACTGGCTACTTACT
GTTCGATATGCCTTATTTACTCGAGTGGAAAGATGCCGTTATTGATGAAATGGCAAAACAATTCCACTGGAGTGATGAAG
TAAAACAAACCTATATAGAAGAATTAGATATTCAAATTAATGATGCTAGAGAGCCGGCTGATTGGCACGATAGATAA

Upstream 100 bases:

>100_bases
TGTTTTTTTAAAGCTTAAAGCGTTTCAGTTAGATGAAAAAGTGGAAAAGTGAGAAGAAGGCATTATTCAGATGGTAAACA
ATTTGAAGGGGGCAAACAAA

Downstream 100 bases:

>100_bases
TTAATCATGAAAAAGCGCTTATCTTTTGAGATTTGCGCTTTTTTTATGAAAAAAAGCATTTTCGCTATTTTCAAGAACCC
ATTTTCATGGTACATTGATT

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATTRGMNVALVEMGDFASGTSSRSTKLVHGGLRYLQQFEIK
EVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTASFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLK
GSGYYVEYRTDDARLTIEVMKKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLTGKAYDIKGHRVINAAGPWVDKVR
KLDYATNNKHLRLTKGIHLVIDKKKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVYDEAVINPKALESDHNYVIKA
INYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKDEVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLTKETG
KKYKPVQTKHLPISGGDIGGSEQLESFLSKKAKEGNNRFGWTLEEGREIAKRYGSNIDQLFTYAQEHKEQEESTLPNSLY
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVIDEMAKQFHWSDEVKQTYIEELDIQINDAREPADWHDR

Sequences:

>Translated_558_residues
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATTRGMNVALVEMGDFASGTSSRSTKLVHGGLRYLQQFEIK
EVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTASFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLK
GSGYYVEYRTDDARLTIEVMKKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLTGKAYDIKGHRVINAAGPWVDKVR
KLDYATNNKHLRLTKGIHLVIDKKKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVYDEAVINPKALESDHNYVIKA
INYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKDEVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLTKETG
KKYKPVQTKHLPISGGDIGGSEQLESFLSKKAKEGNNRFGWTLEEGREIAKRYGSNIDQLFTYAQEHKEQEESTLPNSLY
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVIDEMAKQFHWSDEVKQTYIEELDIQINDAREPADWHDR
>Mature_558_residues
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATTRGMNVALVEMGDFASGTSSRSTKLVHGGLRYLQQFEIK
EVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTASFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLK
GSGYYVEYRTDDARLTIEVMKKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLTGKAYDIKGHRVINAAGPWVDKVR
KLDYATNNKHLRLTKGIHLVIDKKKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVYDEAVINPKALESDHNYVIKA
INYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKDEVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLTKETG
KKYKPVQTKHLPISGGDIGGSEQLESFLSKKAKEGNNRFGWTLEEGREIAKRYGSNIDQLFTYAQEHKEQEESTLPNSLY
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVIDEMAKQFHWSDEVKQTYIEELDIQINDAREPADWHDR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=558, Percent_Identity=34.4086021505376, Blast_Score=266, Evalue=5e-71,
Organism=Homo sapiens, GI285002231, Length=558, Percent_Identity=34.4086021505376, Blast_Score=266, Evalue=5e-71,
Organism=Escherichia coli, GI2367226, Length=478, Percent_Identity=30.5439330543933, Blast_Score=165, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17509253, Length=556, Percent_Identity=31.8345323741007, Blast_Score=235, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI115534726, Length=554, Percent_Identity=30.6859205776173, Blast_Score=228, Evalue=5e-60,
Organism=Saccharomyces cerevisiae, GI6322036, Length=600, Percent_Identity=30.1666666666667, Blast_Score=239, Evalue=1e-63,
Organism=Drosophila melanogaster, GI161077125, Length=554, Percent_Identity=33.7545126353791, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24653942, Length=554, Percent_Identity=33.7545126353791, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24653944, Length=554, Percent_Identity=33.7545126353791, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI20130025, Length=554, Percent_Identity=33.7545126353791, Blast_Score=256, Evalue=4e-68,
Organism=Drosophila melanogaster, GI24586295, Length=556, Percent_Identity=26.6187050359712, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19921278, Length=548, Percent_Identity=26.2773722627737, Blast_Score=162, Evalue=6e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 63365; Mature: 63365

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATTRGMNVALVEMGDFASGTS
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCC
SRSTKLVHGGLRYLQQFEIKEVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHH
SFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLKGSGYYVEYRTDDARLTIEVM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEHHHH
KKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLTGKAYDIKGHRVINAAGPWVDKVR
HHHHHHCCCCCCCCCCHHEEECCCCEEEEEEEECCCCCCEEECCCCEEEECCCCHHHHHH
KLDYATNNKHLRLTKGIHLVIDKKKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVY
HHCCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCEEEEECCCCHH
DEAVINPKALESDHNYVIKAINYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKD
HHHCCCCHHHCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCEEEECCCCHHHHCCCC
EVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLTKETGKKYKPVQTKHLPISGGDIGG
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCC
SEQLESFLSKKAKEGNNRFGWTLEEGREIAKRYGSNIDQLFTYAQEHKEQEESTLPNSLY
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHH
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVIDEMAKQFHWSDEVKQTYIE
HHHHHHHHHHHHCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ELDIQINDAREPADWHDR
HHCEEEECCCCCCCCCCC
>Mature Secondary Structure
MVQLFSAFDRETIERNLQEEKFDLVIVGGGITGAGIALDATTRGMNVALVEMGDFASGTS
CCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCEEEEEEECCCCCCCC
SRSTKLVHGGLRYLQQFEIKEVADLGKERAIVYENGPHVTTPEWMMLPFHKGGNMGKTTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHH
SFGIRLYDYLAGVKKNERRKILSAKETLAKNPFVKKDGLKGSGYYVEYRTDDARLTIEVM
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCEEEHHHH
KKAVELGANAINYTKAEHFLYDDNKQVVGVTVTDRLTGKAYDIKGHRVINAAGPWVDKVR
HHHHHHCCCCCCCCCCHHEEECCCCEEEEEEEECCCCCCEEECCCCEEEECCCCHHHHHH
KLDYATNNKHLRLTKGIHLVIDKKKFPMEQAVYFDTPDGRMVFAIPRDKKVYVGTTDTVY
HHCCCCCCCEEEEECCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCEEEEECCCCHH
DEAVINPKALESDHNYVIKAINYMFPDVHITEKDIESSWAGVRPLIYEEGKDPSEISRKD
HHHCCCCHHHCCCCCHHHHHHHHHCCCCEEEHHHHHCCCCCCCCEEEECCCCHHHHCCCC
EVWFSESGLITMAGGKLTGYRKMAEKLLDDVSKTLTKETGKKYKPVQTKHLPISGGDIGG
CEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCCCC
SEQLESFLSKKAKEGNNRFGWTLEEGREIAKRYGSNIDQLFTYAQEHKEQEESTLPNSLY
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHH
AELRYSIQHEAVTTPIDFLLRRTGYLLFDMPYLLEWKDAVIDEMAKQFHWSDEVKQTYIE
HHHHHHHHHHHHCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ELDIQINDAREPADWHDR
HHCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA