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The map label for this gene is xerC [H]

Identifier: 116872710

GI number: 116872710

Start: 1284728

End: 1285630

Strand: Direct

Name: xerC [H]

Synonym: lwe1294

Alternate gene names: 116872710

Gene position: 1284728-1285630 (Clockwise)

Preceding gene: 116872709

Following gene: 116872711

Centisome position: 45.65

GC content: 35.66

Gene sequence:

>903_bases
ATGACACAAGAGGGAAAGTTAGAGCAACAATTTCTGAATTATCTTCACTCAGAACGAAACTATTCAGTAAACACAAGTAC
TGCTTACGAAAATGATATACTTGATTTTCGTCGCTTCTTAAATGAACAAGCTATTTCAGAATATCAACAAGTCACTTTTT
TAGATGTTCGAATTTATTTAACTGAATTAAAACAAAAATCTTTTTCTCGAACAACTGTGGCTAGAAAGATTTCAAGTTTA
CGGAGTTTTTACACTTTTCTTTTAAGAGAGAATGTGATATCTGAAAACCCGTTTACTTACGTTTCACATGCGAAGAATCA
GCTAAGGCTTCCCAAATTTTTCTATTCAGAAGAAATGGAAGCTTTGTTTCAAGTGGTTTATGAAGATAATGAAACGCTTA
CACTTAGGGATCGAGTTTTATTAGAAGTGCTTTACGGAACTGGCATTCGCGTGAGTGAGTGCGCAGGAATATTGCTTTCT
GACTTAGATACATCTTATCAAGCGATTCTTATTCGTGGAAAAGGGAATAAAGAACGTTATGTACCTTTTGGAGCGTATGC
AGAAGATGCTATAACGGATTATTTGTCTAGTCGAACGGAATTAATGATTCGTTTCAAAAAAGAGCATGATTCATTACTTA
TTAATCATTACGGGGACCCGCTGACGACAAGAGGGATTAGATATTGTTTAACGAAAATAATTAGTAAAGCTTCTTTAACT
CGAAAAATACATCCCCATATGTTGCGCCATACCTTTGCAACAGACTTATTAAATAATGGAGCGGATATGAGGACAGTGCA
GGAGTTGCTTGGACACGCTAGCTTATCATCCACCCAGATATATACGCACGTTACAAAAGAACATTTGAAATCTACCTATA
TGAAACATCATCCTAGGGCTTGA

Upstream 100 bases:

>100_bases
GTAAATCCTAATTAATTCAAAAAGTTGTGAAAAATGGATAAAATTATTGCAACAAGTATATTCTTATGTTAACATGATAG
TGTTTGAGAGGTGTATTTGT

Downstream 100 bases:

>100_bases
ATTTGGAGGAGGTTAAGAAAATGGAACTACATGCAACAACAATATTCGCGGTTCAACATGATGGAAAAGCTGCAATGGCT
GGAGACGGACAAGTGACACT

Product: integrase/recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 299

Protein sequence:

>300_residues
MTQEGKLEQQFLNYLHSERNYSVNTSTAYENDILDFRRFLNEQAISEYQQVTFLDVRIYLTELKQKSFSRTTVARKISSL
RSFYTFLLRENVISENPFTYVSHAKNQLRLPKFFYSEEMEALFQVVYEDNETLTLRDRVLLEVLYGTGIRVSECAGILLS
DLDTSYQAILIRGKGNKERYVPFGAYAEDAITDYLSSRTELMIRFKKEHDSLLINHYGDPLTTRGIRYCLTKIISKASLT
RKIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA

Sequences:

>Translated_300_residues
MTQEGKLEQQFLNYLHSERNYSVNTSTAYENDILDFRRFLNEQAISEYQQVTFLDVRIYLTELKQKSFSRTTVARKISSL
RSFYTFLLRENVISENPFTYVSHAKNQLRLPKFFYSEEMEALFQVVYEDNETLTLRDRVLLEVLYGTGIRVSECAGILLS
DLDTSYQAILIRGKGNKERYVPFGAYAEDAITDYLSSRTELMIRFKKEHDSLLINHYGDPLTTRGIRYCLTKIISKASLT
RKIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA
>Mature_299_residues
TQEGKLEQQFLNYLHSERNYSVNTSTAYENDILDFRRFLNEQAISEYQQVTFLDVRIYLTELKQKSFSRTTVARKISSLR
SFYTFLLRENVISENPFTYVSHAKNQLRLPKFFYSEEMEALFQVVYEDNETLTLRDRVLLEVLYGTGIRVSECAGILLSD
LDTSYQAILIRGKGNKERYVPFGAYAEDAITDYLSSRTELMIRFKKEHDSLLINHYGDPLTTRGIRYCLTKIISKASLTR
KIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=36.3013698630137, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=35.8803986710963, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34993; Mature: 34862

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEGKLEQQFLNYLHSERNYSVNTSTAYENDILDFRRFLNEQAISEYQQVTFLDVRIYL
CCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TELKQKSFSRTTVARKISSLRSFYTFLLRENVISENPFTYVSHAKNQLRLPKFFYSEEME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHH
ALFQVVYEDNETLTLRDRVLLEVLYGTGIRVSECAGILLSDLDTSYQAILIRGKGNKERY
HHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
VPFGAYAEDAITDYLSSRTELMIRFKKEHDSLLINHYGDPLTTRGIRYCLTKIISKASLT
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RKIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TQEGKLEQQFLNYLHSERNYSVNTSTAYENDILDFRRFLNEQAISEYQQVTFLDVRIYL
CCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TELKQKSFSRTTVARKISSLRSFYTFLLRENVISENPFTYVSHAKNQLRLPKFFYSEEME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHH
ALFQVVYEDNETLTLRDRVLLEVLYGTGIRVSECAGILLSDLDTSYQAILIRGKGNKERY
HHHHHHHCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCCCC
VPFGAYAEDAITDYLSSRTELMIRFKKEHDSLLINHYGDPLTTRGIRYCLTKIISKASLT
CCCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHH
RKIHPHMLRHTFATDLLNNGADMRTVQELLGHASLSSTQIYTHVTKEHLKSTYMKHHPRA
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]