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The map label for this gene is yggV [C]

Identifier: 116872610

GI number: 116872610

Start: 1206241

End: 1206852

Strand: Direct

Name: yggV [C]

Synonym: lwe1194

Alternate gene names: 116872610

Gene position: 1206241-1206852 (Clockwise)

Preceding gene: 116872609

Following gene: 116872611

Centisome position: 42.86

GC content: 38.4

Gene sequence:

>612_bases
ATGAGTAAAATTATTATTGCCACCGCAAATAAAGGAAAAGCAAAAGAATTCGAAAAAATCTTTGCTAAATTTAATATTGA
AGTTGCGACACTTGCTGATTTCCCGGAAATAGGTGAAATTGAAGAAACAGGAACAACTTTTGCTGAAAATGCTGCTCTCA
AGGCAGAAACAGTCGCTAGCTTGCTAAATCAAACCGTAATTGCTGATGATTCCGGATTAATCGTAGACGCGCTTGACGGA
GCTCCTGGCGTCTATTCGGCACGCTATGCTGGTGTCGCCCACGATGATGCCAAAAATAATGAAAAACTACTTAAAAATTT
AGAAGGTGTGGAACCGGCCAAAAGAACAGCGCGTTTCCATTGTACACTTGCTGTAGCTACACCGTCTGAAAAAACTACTT
TTTATACTGGAGAAGTAGAGGGGATAATTGCAGAACAACTTTGTGGAACAAATGGATTTGGTTATGATCCACTATTTTTC
TTACCTGAATACGGTTTAACAATGGCTGAAATCCCAGCTGAGAAAAAGAATGAAATTAGCCACCGTGCGAATGCCATTAA
ACAACTAGAAAAAGATTTAACAGAAGTAGTAGAAAAAGTTACTAAAAAGTGA

Upstream 100 bases:

>100_bases
ACTAATTGCTCTAGGTAAAAAAGGAATAAGTGAACTAATCGAAATCCAAAAAGAAATACTTGGCGACAAAATCACAGCGC
GGATTAAAGGAGAATAAAAG

Downstream 100 bases:

>100_bases
GAGAATAGGTAACAGTAGCACTAGGGGGAGGAACCAAAATGAAATTATTAGTAGTTAGCGACAGTCACTCAGAACGTGAT
TGTTTAATCCATCTTAAAGA

Product: nucleoside-triphosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 203; Mature: 202

Protein sequence:

>203_residues
MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASLLNQTVIADDSGLIVDALDG
APGVYSARYAGVAHDDAKNNEKLLKNLEGVEPAKRTARFHCTLAVATPSEKTTFYTGEVEGIIAEQLCGTNGFGYDPLFF
LPEYGLTMAEIPAEKKNEISHRANAIKQLEKDLTEVVEKVTKK

Sequences:

>Translated_203_residues
MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASLLNQTVIADDSGLIVDALDG
APGVYSARYAGVAHDDAKNNEKLLKNLEGVEPAKRTARFHCTLAVATPSEKTTFYTGEVEGIIAEQLCGTNGFGYDPLFF
LPEYGLTMAEIPAEKKNEISHRANAIKQLEKDLTEVVEKVTKK
>Mature_202_residues
SKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVASLLNQTVIADDSGLIVDALDGA
PGVYSARYAGVAHDDAKNNEKLLKNLEGVEPAKRTARFHCTLAVATPSEKTTFYTGEVEGIIAEQLCGTNGFGYDPLFFL
PEYGLTMAEIPAEKKNEISHRANAIKQLEKDLTEVVEKVTKK

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=195, Percent_Identity=31.2820512820513, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789324, Length=191, Percent_Identity=45.0261780104712, Blast_Score=164, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19920712, Length=198, Percent_Identity=31.3131313131313, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22000; Mature: 21869

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVAS
CCEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHCCCCHHHCCHHHHHHHHH
LLNQTVIADDSGLIVDALDGAPGVYSARYAGVAHDDAKNNEKLLKNLEGVEPAKRTARFH
HHHHHEEECCCCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHCEEEE
CTLAVATPSEKTTFYTGEVEGIIAEQLCGTNGFGYDPLFFLPEYGLTMAEIPAEKKNEIS
EEEEEECCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHCCCHHHHHHH
HRANAIKQLEKDLTEVVEKVTKK
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SKIIIATANKGKAKEFEKIFAKFNIEVATLADFPEIGEIEETGTTFAENAALKAETVAS
CEEEEEECCCCCHHHHHHHHHHHCCEEEEECCCCCCCCHHHCCCCHHHCCHHHHHHHHH
LLNQTVIADDSGLIVDALDGAPGVYSARYAGVAHDDAKNNEKLLKNLEGVEPAKRTARFH
HHHHHEEECCCCEEEEECCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCHHHHCEEEE
CTLAVATPSEKTTFYTGEVEGIIAEQLCGTNGFGYDPLFFLPEYGLTMAEIPAEKKNEIS
EEEEEECCCCCCEEEECCHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHCCCHHHHHHH
HRANAIKQLEKDLTEVVEKVTKK
HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]