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The map label for this gene is pheT [H]

Identifier: 116872593

GI number: 116872593

Start: 1182926

End: 1185334

Strand: Direct

Name: pheT [H]

Synonym: lwe1177

Alternate gene names: 116872593

Gene position: 1182926-1185334 (Clockwise)

Preceding gene: 116872592

Following gene: 116872594

Centisome position: 42.04

GC content: 38.9

Gene sequence:

>2409_bases
ATGTTAGTTTCATATAATTGGGTAAAAGAATTTTTCCAAGACTTCCCTTTAACGGCGGAAGAGCTAGGAGAAGCAATTAC
AAGAACTGGAATCGAAATCGAAGGCGTAGAAGAATTAAGCGCTAGTTTGAAAAATGTTGTAGTGGGGGAAGTTTTATCAT
GTGAACGCCACCCAGATGCAGAAAAATTGAATAAATGCATCGTTCAAACAGACGAAAATGAACCAGTTCAAATTATTTGC
GGCGCACCAAATGTAGCTGCTGGTCAAAAAGTTATCGTAGCCAAAGTTGGCGCAAGACTTCCAGGCGGACTTAAAATCAA
ACGAGCTAAACTACGCGGTGAAGTGTCAGAAGGAATGATTTGTTCTCTTTCTGAACTAGGCTTTGAAAGTAAAGTTGTAC
CAAAAGCATATGCAGATGGTATATATGTATTACCAGATCATGTTGAAACAGGGGTAAGCGCGATTACATTACTCGGTTTA
GATGATGCGATTCTTGATATGGCTATCACTCCCAATCGTGCAGACGCATTAAGTATGAATGGTGTAGCTCACGAAGTAGG
CGCGATTATTCATCAAAAACCAGCACAACCAACAGAACCCGACGTATCTGAAAAAGGGAAAGCAGATGACTTTATTTCTG
TAGAAGTGGAAAATCCAGCTGAAACCCCTTATTATGCTATTAAAATGGTCGAAAATATCGAAATTAAAGAATCACCACTT
TGGTTGCAAACAAAATTGATGAAGGCTGGCATTCGTCCTCATAATAATGTGGTTGATGTAACAAATTACATCAATTTATT
ATACGGACAACCCCTTCATTCCTTTGATTATGATAAAATCGGCAGCAAAAAAATCGTTGTCCGTTCCGCAAAAGAGCAAG
AAGAAATTACCACACTAGATGGCGAGAAAAGAACTTTACAAGCAGGTCATACAGTCATTACGAACGGAATAGAACCAATT
GCTATTGCGGGTGTTATGGGCGGTGAATTTTCTGAAGTAACTCATAGCACAACGACTGTAGCGCTTGAGGGAGCTATTTT
CAGTAGTTCATCTATCGGAAAAGCATCTCGCGAATTATATTTACGCACAGAAGCAAGTATCCGTTACGACAAAGGATCGG
ATGCTTGGAAAGTAGAAAAAGCACTGGCACACGGCGGAGCGCTTATCGCTGAACTGAGCGGCGGCACGCTAATTGGCGGT
GTGGTGGAAGTGGATAATCGTAAAAAAGCAGTGAATAAAATCGAAACAAGTTTAACTCGTATTAACCGTATTCTAGGAAC
AACAATTACCCTTTCTGAAATAAAAACTATTTTTGATCGTTTAGGCTTTGTGTTAGAAGTAAAAGAGGACAAATTGATTG
TTGAAGTACCGACTAGACGTTGGGATATTACGATTGAAGCGGACATTTTAGAAGAAGTAGCACGTATTTATGGTTATGAT
GAAATTCCAGTAACTTTACCAGCGACAAGTACAACTGGCGGCTTATCTGAAAGTCAAAAAGCTCGTCGGGTGATGCGCGC
TTATTTAGAATGTGCAGGACTTAACCAAGCATTAACTTATTCTTTAACTTCTAAAAAAGATGCAACACGCTTAGCTTTAT
CTGATGAAAAAACCGTGGCGCTCTCGATGCCTATGAGTGAGGAACATAGCCATTTAAGAACAAGTATTGTCCCACAATTA
ATCCGTAGTGCAAGTTATAATATTGCTCGTAAAAATATGGATGTGGCCCTTTACGAAATGGGAACTGTGTTTTATGCAAC
AGAAGGCGACAATTTACCAATCGAACAAGAACATTTAGCAGGCTTAATTACTGGGAATTGGCACACTTCCGATTGGCAAA
AAACACCAAAACCAGTAGATTTCTTTGTTTTAAAAGGGATTGTGGAAGGCTTAGTGAATAAACTAGGAATCAAAGCTGAG
CTACACTGGAATCAAACAGAAAAAGAAGAACTGCATCCAGGAAGAACGGCAAGTATCCAGTTAGAAGGAAAAGAAATTGG
TTACCTTGGTGCACTTCATCCAGCTGTAGAAGCAAACTATGATTTAAAAGAAACTTATGTATTTGAAATTAATGTAGAAG
CTTTACTTGAAGCGACAAAAGAAAAAGTTGTTTATCATCCAATCCCGCGTTATCCGGAAATGACTCGTGACTTAGCATTA
CTAGTTGATAAAGATATCAACCACGCAACCATATCAGAAGTAATCAAAGAACACGGCGGGAAACTACTAGTAGACATCGA
GCTATTTGATATTTTTGAAGGTGAAAGTCTGGGAGAAAATAAAAAATCACTCGCATATACGTTAACTTTCCTTGATAGCG
AAAGAACGCTTGTAGAAGAAGATGTCCAAAAAGCGACTAACAAAGTAGTGGAAGCATTACAAACAAAACTGAATGCGATT
ATTCGCTAA

Upstream 100 bases:

>100_bases
TTGCAATGTTGAAATACGCGGTCGATGATATTCGCCATTTATATACGAATGATTTACGTTTTACCAAGCAATTCCAAAGC
ACAGAAACGGGGGAAATCTA

Downstream 100 bases:

>100_bases
ATAAAAAATGAACTAATCTATTTGGAAAACATTTCTATATAGGTTAGTTCTTTTTTTGTATATTTTTATCTTTTTATTGA
ATTACTGTAAGCTTTTCATT

Product: phenylalanyl-tRNA synthetase subunit beta

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase beta chain; PheRS [H]

Number of amino acids: Translated: 802; Mature: 802

Protein sequence:

>802_residues
MLVSYNWVKEFFQDFPLTAEELGEAITRTGIEIEGVEELSASLKNVVVGEVLSCERHPDAEKLNKCIVQTDENEPVQIIC
GAPNVAAGQKVIVAKVGARLPGGLKIKRAKLRGEVSEGMICSLSELGFESKVVPKAYADGIYVLPDHVETGVSAITLLGL
DDAILDMAITPNRADALSMNGVAHEVGAIIHQKPAQPTEPDVSEKGKADDFISVEVENPAETPYYAIKMVENIEIKESPL
WLQTKLMKAGIRPHNNVVDVTNYINLLYGQPLHSFDYDKIGSKKIVVRSAKEQEEITTLDGEKRTLQAGHTVITNGIEPI
AIAGVMGGEFSEVTHSTTTVALEGAIFSSSSIGKASRELYLRTEASIRYDKGSDAWKVEKALAHGGALIAELSGGTLIGG
VVEVDNRKKAVNKIETSLTRINRILGTTITLSEIKTIFDRLGFVLEVKEDKLIVEVPTRRWDITIEADILEEVARIYGYD
EIPVTLPATSTTGGLSESQKARRVMRAYLECAGLNQALTYSLTSKKDATRLALSDEKTVALSMPMSEEHSHLRTSIVPQL
IRSASYNIARKNMDVALYEMGTVFYATEGDNLPIEQEHLAGLITGNWHTSDWQKTPKPVDFFVLKGIVEGLVNKLGIKAE
LHWNQTEKEELHPGRTASIQLEGKEIGYLGALHPAVEANYDLKETYVFEINVEALLEATKEKVVYHPIPRYPEMTRDLAL
LVDKDINHATISEVIKEHGGKLLVDIELFDIFEGESLGENKKSLAYTLTFLDSERTLVEEDVQKATNKVVEALQTKLNAI
IR

Sequences:

>Translated_802_residues
MLVSYNWVKEFFQDFPLTAEELGEAITRTGIEIEGVEELSASLKNVVVGEVLSCERHPDAEKLNKCIVQTDENEPVQIIC
GAPNVAAGQKVIVAKVGARLPGGLKIKRAKLRGEVSEGMICSLSELGFESKVVPKAYADGIYVLPDHVETGVSAITLLGL
DDAILDMAITPNRADALSMNGVAHEVGAIIHQKPAQPTEPDVSEKGKADDFISVEVENPAETPYYAIKMVENIEIKESPL
WLQTKLMKAGIRPHNNVVDVTNYINLLYGQPLHSFDYDKIGSKKIVVRSAKEQEEITTLDGEKRTLQAGHTVITNGIEPI
AIAGVMGGEFSEVTHSTTTVALEGAIFSSSSIGKASRELYLRTEASIRYDKGSDAWKVEKALAHGGALIAELSGGTLIGG
VVEVDNRKKAVNKIETSLTRINRILGTTITLSEIKTIFDRLGFVLEVKEDKLIVEVPTRRWDITIEADILEEVARIYGYD
EIPVTLPATSTTGGLSESQKARRVMRAYLECAGLNQALTYSLTSKKDATRLALSDEKTVALSMPMSEEHSHLRTSIVPQL
IRSASYNIARKNMDVALYEMGTVFYATEGDNLPIEQEHLAGLITGNWHTSDWQKTPKPVDFFVLKGIVEGLVNKLGIKAE
LHWNQTEKEELHPGRTASIQLEGKEIGYLGALHPAVEANYDLKETYVFEINVEALLEATKEKVVYHPIPRYPEMTRDLAL
LVDKDINHATISEVIKEHGGKLLVDIELFDIFEGESLGENKKSLAYTLTFLDSERTLVEEDVQKATNKVVEALQTKLNAI
IR
>Mature_802_residues
MLVSYNWVKEFFQDFPLTAEELGEAITRTGIEIEGVEELSASLKNVVVGEVLSCERHPDAEKLNKCIVQTDENEPVQIIC
GAPNVAAGQKVIVAKVGARLPGGLKIKRAKLRGEVSEGMICSLSELGFESKVVPKAYADGIYVLPDHVETGVSAITLLGL
DDAILDMAITPNRADALSMNGVAHEVGAIIHQKPAQPTEPDVSEKGKADDFISVEVENPAETPYYAIKMVENIEIKESPL
WLQTKLMKAGIRPHNNVVDVTNYINLLYGQPLHSFDYDKIGSKKIVVRSAKEQEEITTLDGEKRTLQAGHTVITNGIEPI
AIAGVMGGEFSEVTHSTTTVALEGAIFSSSSIGKASRELYLRTEASIRYDKGSDAWKVEKALAHGGALIAELSGGTLIGG
VVEVDNRKKAVNKIETSLTRINRILGTTITLSEIKTIFDRLGFVLEVKEDKLIVEVPTRRWDITIEADILEEVARIYGYD
EIPVTLPATSTTGGLSESQKARRVMRAYLECAGLNQALTYSLTSKKDATRLALSDEKTVALSMPMSEEHSHLRTSIVPQL
IRSASYNIARKNMDVALYEMGTVFYATEGDNLPIEQEHLAGLITGNWHTSDWQKTPKPVDFFVLKGIVEGLVNKLGIKAE
LHWNQTEKEELHPGRTASIQLEGKEIGYLGALHPAVEANYDLKETYVFEINVEALLEATKEKVVYHPIPRYPEMTRDLAL
LVDKDINHATISEVIKEHGGKLLVDIELFDIFEGESLGENKKSLAYTLTFLDSERTLVEEDVQKATNKVVEALQTKLNAI
IR

Specific function: Unknown

COG id: COG0072

COG function: function code J; Phenylalanyl-tRNA synthetase beta subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 tRNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI124028525, Length=288, Percent_Identity=27.4305555555556, Blast_Score=96, Evalue=2e-19,
Organism=Escherichia coli, GI1788006, Length=809, Percent_Identity=36.0939431396786, Blast_Score=444, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17533403, Length=579, Percent_Identity=22.279792746114, Blast_Score=86, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323089, Length=315, Percent_Identity=23.8095238095238, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355211, Length=555, Percent_Identity=21.0810810810811, Blast_Score=96, Evalue=8e-20,

Paralogues:

None

Copy number: 1,800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005146
- InterPro:   IPR005147
- InterPro:   IPR009061
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004532
- InterPro:   IPR020825
- InterPro:   IPR005121
- InterPro:   IPR002547 [H]

Pfam domain/function: PF03483 B3_4; PF03484 B5; PF03147 FDX-ACB; PF01588 tRNA_bind [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 88277; Mature: 88277

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50886 TRBD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSYNWVKEFFQDFPLTAEELGEAITRTGIEIEGVEELSASLKNVVVGEVLSCERHPDA
CEECHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCH
EKLNKCIVQTDENEPVQIICGAPNVAAGQKVIVAKVGARLPGGLKIKRAKLRGEVSEGMI
HHHHHHEEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEHHHHCCCCCCCCE
CSLSELGFESKVVPKAYADGIYVLPDHVETGVSAITLLGLDDAILDMAITPNRADALSMN
EEHHHCCCCCCCCCHHHCCCEEEECCCHHCCCCEEEEECCCHHHHEEEECCCCCCCEECC
GVAHEVGAIIHQKPAQPTEPDVSEKGKADDFISVEVENPAETPYYAIKMVENIEIKESPL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCEECCCCC
WLQTKLMKAGIRPHNNVVDVTNYINLLYGQPLHSFDYDKIGSKKIVVRSAKEQEEITTLD
HHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCC
GEKRTLQAGHTVITNGIEPIAIAGVMGGEFSEVTHSTTTVALEGAIFSSSSIGKASRELY
CCCHHHHCCCEEEECCCCCEEEEEECCCCHHHHCCCCEEEEEECEEECCCCCCCCCCEEE
LRTEASIRYDKGSDAWKVEKALAHGGALIAELSGGTLIGGVVEVDNRKKAVNKIETSLTR
EEECCEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEEEEEEEECCHHHHHHHHHHHHHH
INRILGTTITLSEIKTIFDRLGFVLEVKEDKLIVEVPTRRWDITIEADILEEVARIYGYD
HHHHHCCEEEHHHHHHHHHHCCEEEEEECCEEEEEECCCEEEEEEEHHHHHHHHHHCCCC
EIPVTLPATSTTGGLSESQKARRVMRAYLECAGLNQALTYSLTSKKDATRLALSDEKTVA
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCEEEEECCCCEEE
LSMPMSEEHSHLRTSIVPQLIRSASYNIARKNMDVALYEMGTVFYATEGDNLPIEQEHLA
EECCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECEEEEEECCCCCCCCHHHCE
GLITGNWHTSDWQKTPKPVDFFVLKGIVEGLVNKLGIKAELHWNQTEKEELHPGRTASIQ
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCEEEEE
LEGKEIGYLGALHPAVEANYDLKETYVFEINVEALLEATKEKVVYHPIPRYPEMTRDLAL
ECCCCCCEEECCCCHHCCCCCCCEEEEEEEEHHHHHHHHHHCEEECCCCCCCHHHHHHEE
LVDKDINHATISEVIKEHGGKLLVDIELFDIFEGESLGENKKSLAYTLTFLDSERTLVEE
EEECCCCHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHH
DVQKATNKVVEALQTKLNAIIR
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLVSYNWVKEFFQDFPLTAEELGEAITRTGIEIEGVEELSASLKNVVVGEVLSCERHPDA
CEECHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHCCCCCCH
EKLNKCIVQTDENEPVQIICGAPNVAAGQKVIVAKVGARLPGGLKIKRAKLRGEVSEGMI
HHHHHHEEECCCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCEEEHHHHCCCCCCCCE
CSLSELGFESKVVPKAYADGIYVLPDHVETGVSAITLLGLDDAILDMAITPNRADALSMN
EEHHHCCCCCCCCCHHHCCCEEEECCCHHCCCCEEEEECCCHHHHEEEECCCCCCCEECC
GVAHEVGAIIHQKPAQPTEPDVSEKGKADDFISVEVENPAETPYYAIKMVENIEIKESPL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEEEECCEECCCCC
WLQTKLMKAGIRPHNNVVDVTNYINLLYGQPLHSFDYDKIGSKKIVVRSAKEQEEITTLD
HHHHHHHHCCCCCCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCHHHHHCCC
GEKRTLQAGHTVITNGIEPIAIAGVMGGEFSEVTHSTTTVALEGAIFSSSSIGKASRELY
CCCHHHHCCCEEEECCCCCEEEEEECCCCHHHHCCCCEEEEEECEEECCCCCCCCCCEEE
LRTEASIRYDKGSDAWKVEKALAHGGALIAELSGGTLIGGVVEVDNRKKAVNKIETSLTR
EEECCEEEECCCCCHHHHHHHHHCCCEEEEEECCCEEEEEEEEECCHHHHHHHHHHHHHH
INRILGTTITLSEIKTIFDRLGFVLEVKEDKLIVEVPTRRWDITIEADILEEVARIYGYD
HHHHHCCEEEHHHHHHHHHHCCEEEEEECCEEEEEECCCEEEEEEEHHHHHHHHHHCCCC
EIPVTLPATSTTGGLSESQKARRVMRAYLECAGLNQALTYSLTSKKDATRLALSDEKTVA
CCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCCEEEEECCCCEEE
LSMPMSEEHSHLRTSIVPQLIRSASYNIARKNMDVALYEMGTVFYATEGDNLPIEQEHLA
EECCCCHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEEECEEEEEECCCCCCCCHHHCE
GLITGNWHTSDWQKTPKPVDFFVLKGIVEGLVNKLGIKAELHWNQTEKEELHPGRTASIQ
EEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHCCCCCEEEEE
LEGKEIGYLGALHPAVEANYDLKETYVFEINVEALLEATKEKVVYHPIPRYPEMTRDLAL
ECCCCCCEEECCCCHHCCCCCCCEEEEEEEEHHHHHHHHHHCEEECCCCCCCHHHHHHEE
LVDKDINHATISEVIKEHGGKLLVDIELFDIFEGESLGENKKSLAYTLTFLDSERTLVEE
EEECCCCHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHH
DVQKATNKVVEALQTKLNAIIR
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]