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The map label for this gene is lytG [H]

Identifier: 116872588

GI number: 116872588

Start: 1178040

End: 1179053

Strand: Direct

Name: lytG [H]

Synonym: lwe1172

Alternate gene names: 116872588

Gene position: 1178040-1179053 (Clockwise)

Preceding gene: 116872587

Following gene: 116872589

Centisome position: 41.86

GC content: 36.0

Gene sequence:

>1014_bases
ATGTTACAACTCGCAAAGAAGCATTTGGTGACAATTGGTCTTGGAATTACAATTACATTATGTGCCTTACCAATCCACTC
CCAAGCTGCTGGTCTAGAGGACGGCCTGACTTCCAAGCAAGAGAAGTTTATTAATGAGATTGCGCCGCATGCTCAAAAAG
TGCAAAAAGAACATGGTATTTTAGCAAGTATTACAATTTCGCAAGCAATATTAGAATCCAATTGGGGAAATAGTAAGCTA
GCAAAAGAGGGCAAAAACTTATTTGGTATTAAAGGTTCCTATAAAGGAAATACAATTAAGTTGCCAACTAAAGAACATAA
TGGGATTGTTTGGGTTGGAACGGACGCTGAATTTAGAGCGTATCCAGGCTGGTATGAATCATTGAATGACCATGCGCTTT
TATTTGTTAAAGGCCCATCATGGAATCCTAGTTTATATGCAGGATTAATCAAAGAATATAACTATGAAAATGCAGCCATT
GCACTAGGGAAAACTGGTTATTCATCTGACCCAGAGTATGCAGCGAAATTAATCGAACTAATAAAAAAAGCAAATTTAGA
TAAATATGATACTGTTTATAGTGAACGGATATCAGAAAAAGCAATCAAGGCAGCCGGAGAAGTGGCACCAAAAGACAATT
GCTTTATTTGGTCCGCACCTAGTGGAACAAAAGGTGCAAAAACGATTGAAAGTACTTCGAAATATTTTGGACGTCAAGTG
GCTATTAATCAAGAAGTTAAAGTGACAGACTCTAATATTTCATGGTACCACCTTCATCATAATGGAGAACCAATAGGTTG
GATTGAAAGTACATCAATAAAAAACTTTTACCAACTAGAAGATTATTCTCCAACGATTGCAACTTCCCTAAAAACGGATA
ATCAAAATCGATTAGTGATTAATATGGATGTTGACATATCTGAACTTCATAAGACCAGAATCACTAAAGTAGAAACTAAA
AATAAATCCGCGCTCAATGTACCCTTATTAAACATACAATCTGTTGCATGGTAA

Upstream 100 bases:

>100_bases
TTTTGATAGAATGAAGAAGTTGTTTAAAGGACACTGGTTTCTGGCAACTTTTTTATTTAGCCAGAAGGATAACTCAAAAA
AGGATGTGCAATAAATCATT

Downstream 100 bases:

>100_bases
AATTTAAGTAAAAGCTGGGAATTAACTCAGCTTTTTTTGCGTTTTCAAAGGAATTTTAGAAAGAAACTGTTATAATGGAA
AAGGAGTTTATAAGGAGGTT

Product: N-acetylmuramoyl-L-alanine amidase

Products: NA

Alternate protein names: Autolysin lytG; Exo-beta-N-acetylglucosaminidase lytG; Peptidoglycan hydrolase lytG [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MLQLAKKHLVTIGLGITITLCALPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQAILESNWGNSKL
AKEGKNLFGIKGSYKGNTIKLPTKEHNGIVWVGTDAEFRAYPGWYESLNDHALLFVKGPSWNPSLYAGLIKEYNYENAAI
ALGKTGYSSDPEYAAKLIELIKKANLDKYDTVYSERISEKAIKAAGEVAPKDNCFIWSAPSGTKGAKTIESTSKYFGRQV
AINQEVKVTDSNISWYHLHHNGEPIGWIESTSIKNFYQLEDYSPTIATSLKTDNQNRLVINMDVDISELHKTRITKVETK
NKSALNVPLLNIQSVAW

Sequences:

>Translated_337_residues
MLQLAKKHLVTIGLGITITLCALPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQAILESNWGNSKL
AKEGKNLFGIKGSYKGNTIKLPTKEHNGIVWVGTDAEFRAYPGWYESLNDHALLFVKGPSWNPSLYAGLIKEYNYENAAI
ALGKTGYSSDPEYAAKLIELIKKANLDKYDTVYSERISEKAIKAAGEVAPKDNCFIWSAPSGTKGAKTIESTSKYFGRQV
AINQEVKVTDSNISWYHLHHNGEPIGWIESTSIKNFYQLEDYSPTIATSLKTDNQNRLVINMDVDISELHKTRITKVETK
NKSALNVPLLNIQSVAW
>Mature_337_residues
MLQLAKKHLVTIGLGITITLCALPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGILASITISQAILESNWGNSKL
AKEGKNLFGIKGSYKGNTIKLPTKEHNGIVWVGTDAEFRAYPGWYESLNDHALLFVKGPSWNPSLYAGLIKEYNYENAAI
ALGKTGYSSDPEYAAKLIELIKKANLDKYDTVYSERISEKAIKAAGEVAPKDNCFIWSAPSGTKGAKTIESTSKYFGRQV
AINQEVKVTDSNISWYHLHHNGEPIGWIESTSIKNFYQLEDYSPTIATSLKTDNQNRLVINMDVDISELHKTRITKVETK
NKSALNVPLLNIQSVAW

Specific function: Is the major glucosaminidase responsible for peptidoglycan structural determination during vegetative growth. Acts processively from the ends of the glycan strands. Also plays a role in motility, chemotaxis and cell division [H]

COG id: COG1705

COG function: function code NU; Muramidase (flagellum-specific)

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 73 family [H]

Homologues:

Organism=Escherichia coli, GI1787321, Length=173, Percent_Identity=31.2138728323699, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000423
- InterPro:   IPR013338
- InterPro:   IPR002901 [H]

Pfam domain/function: PF01832 Glucosaminidase [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 37347; Mature: 37347

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLAKKHLVTIGLGITITLCALPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGI
CCCCCCCEEEEEECCEEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
LASITISQAILESNWGNSKLAKEGKNLFGIKGSYKGNTIKLPTKEHNGIVWVGTDAEFRA
EEEEHHHHHHHHCCCCCCHHHHCCCCEEEEECCCCCCEEECCCCCCCCEEEEECCCCCEE
YPGWYESLNDHALLFVKGPSWNPSLYAGLIKEYNYENAAIALGKTGYSSDPEYAAKLIEL
CCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
IKKANLDKYDTVYSERISEKAIKAAGEVAPKDNCFIWSAPSGTKGAKTIESTSKYFGRQV
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEE
AINQEVKVTDSNISWYHLHHNGEPIGWIESTSIKNFYQLEDYSPTIATSLKTDNQNRLVI
EECCEEEEEECCEEEEEEECCCCCCCEEECCCCCCEEEECCCCCCEEEEEECCCCCEEEE
NMDVDISELHKTRITKVETKNKSALNVPLLNIQSVAW
EECCCHHHHHHHHHEEEECCCCCEEECEEEECCCCCC
>Mature Secondary Structure
MLQLAKKHLVTIGLGITITLCALPIHSQAAGLEDGLTSKQEKFINEIAPHAQKVQKEHGI
CCCCCCCEEEEEECCEEEEEEECCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCE
LASITISQAILESNWGNSKLAKEGKNLFGIKGSYKGNTIKLPTKEHNGIVWVGTDAEFRA
EEEEHHHHHHHHCCCCCCHHHHCCCCEEEEECCCCCCEEECCCCCCCCEEEEECCCCCEE
YPGWYESLNDHALLFVKGPSWNPSLYAGLIKEYNYENAAIALGKTGYSSDPEYAAKLIEL
CCCHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHH
IKKANLDKYDTVYSERISEKAIKAAGEVAPKDNCFIWSAPSGTKGAKTIESTSKYFGRQV
HHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCEEE
AINQEVKVTDSNISWYHLHHNGEPIGWIESTSIKNFYQLEDYSPTIATSLKTDNQNRLVI
EECCEEEEEECCEEEEEEECCCCCCCEEECCCCCCEEEECCCCCCEEEEEECCCCCEEEE
NMDVDISELHKTRITKVETKNKSALNVPLLNIQSVAW
EECCCHHHHHHHHHEEEECCCCCEEECEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]