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The map label for this gene is pdtaS [H]

Identifier: 116872547

GI number: 116872547

Start: 1143678

End: 1145135

Strand: Direct

Name: pdtaS [H]

Synonym: lwe1131

Alternate gene names: 116872547

Gene position: 1143678-1145135 (Clockwise)

Preceding gene: 116872546

Following gene: 116872548

Centisome position: 40.64

GC content: 34.09

Gene sequence:

>1458_bases
ATGACTAAAACGATTCGAGAAATGTGCTTACGTTATACAGACTTGGCTGAATATGATATTGATGAATTAATACATACAGC
AAAATCATTAAGCGAGTCTTCTATGTATCAAGATGTTGATGTATTTATTGATGTTTACAACAAACTTACTAGTGAAGCAC
TTGTTATTCATCACATGCCACCAAAAACAACCAAATCACTTTATAAAAACAATGTTGTCGGAGAAACAGCTCTTCGTAGT
AATGAACCAGGTGTACTTAGAACACTTGAAACGGGCATGAACTCCAATGATTTACTAGCAAAAACACAAGAAAACGTATT
AATTCGTCAAAAAGTGTATCCGATTCGAAACAAACAACGCGTGATTGCCGTACTTATTCTAGAAAATGATATTAGTGCAG
AAATTAAAGCACATTTTGAAATCGACAATGAAGAAACGGCTTATAGAGATGTTTCCACGACACTTTCTGCAATGAGCAAA
TTAACTGATTCCATTACAGATCAGCTAGATGACGCCATTTTGATTTTTGATGGTAAAGGTATTTTACAACAAAAAAATTG
CGCGGCAGATCAGTATTATGAACGACTCGGTTACATGGAAAATATCCAAGGAATGCACTATGATAATTTATCACTGGATC
AGATGATGTTTGATGCCATTATGTATCAAATTGAAACAGGAAAACAACCAATTCAACTAAAAAAAGAAGTGGTTATTGCT
GGGAATTACTTTATTATGAAGCAAATTTTTGTGAAGGAGGAGGATGAACAAGAGTGTCGTTTTATTCTTATTCTTCATGA
TATTACGGATATTAAAGTGAAAGAAGCAGAAATTGTTTCGAAATCAGTAGCAATTCGAGAAATTCATCATCGTGTAAAAA
ATAATTTACAATCCGTTGTTTCCTTACTGAGAATTCAAGGTAGGCGCTCCACCAGTGTTGAAGCCCAGAAAGTTTTAAAT
GAAAGTGTCAGCCGAATTCTTGCTATTGCAGCAACACATGAACTTTTATCGAAGCAGATGGAAGACGGAATCAACTTATA
TATGGTTATTGAAACAGTTGCTTATAATGTGGAAAGATGTTGTAACGACTGTCCAAAAGTTGCTGTTCGAATGGATATTG
ATAAACGAATTTATTTGGATAGTGACCGAACTGTGGCACTGGCACTTGTTATGAATGAGCTTTTACAAAACTCATATGAT
CATGCTTTCCATCCAAATGAATCAGGCGAAATTTTACTACAAATAAAAGAAGAAAAAAATATTATTCATGCAGAAGTGAG
CGACAATGGGCATGGATTTAACGTTCGTAAAGTGTCCGAAAAAAGCTTAGGACTCTCCATTGTCAAAAGTTACATCAAAG
ATAAACTCCGAGGAAAAGTAACCATTGAATCAAATGAATTTGGAACAAAAACAATGTTTGATTTTAAATACATTTCAATC
CATGCTACAAAGAAGTAG

Upstream 100 bases:

>100_bases
AATAACATCACAGAAGAAGAAGCTTACAATATGATTCGTAATCTGAGCATGGATAAACGTTGTCCAATGATGGAAATCGC
TGAAACGATTGTGATGAGCG

Downstream 100 bases:

>100_bases
CTATGAAAAAGCGATGAAGCTTAAAGCCAAGTAACGAAACTGTTATTTGTCTTTAAGCTTTTTCTTTTTGTTAGAAAGGA
GTGAGGGTTTTGGCGGAAAC

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTKTIREMCLRYTDLAEYDIDELIHTAKSLSESSMYQDVDVFIDVYNKLTSEALVIHHMPPKTTKSLYKNNVVGETALRS
NEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQRVIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSK
LTDSITDQLDDAILIFDGKGILQQKNCAADQYYERLGYMENIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVVSLLRIQGRRSTSVEAQKVLN
ESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNVERCCNDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYD
HAFHPNESGEILLQIKEEKNIIHAEVSDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEFGTKTMFDFKYISI
HATKK

Sequences:

>Translated_485_residues
MTKTIREMCLRYTDLAEYDIDELIHTAKSLSESSMYQDVDVFIDVYNKLTSEALVIHHMPPKTTKSLYKNNVVGETALRS
NEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQRVIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSK
LTDSITDQLDDAILIFDGKGILQQKNCAADQYYERLGYMENIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVVSLLRIQGRRSTSVEAQKVLN
ESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNVERCCNDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYD
HAFHPNESGEILLQIKEEKNIIHAEVSDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEFGTKTMFDFKYISI
HATKK
>Mature_484_residues
TKTIREMCLRYTDLAEYDIDELIHTAKSLSESSMYQDVDVFIDVYNKLTSEALVIHHMPPKTTKSLYKNNVVGETALRSN
EPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQRVIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSKL
TDSITDQLDDAILIFDGKGILQQKNCAADQYYERLGYMENIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIAG
NYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVVSLLRIQGRRSTSVEAQKVLNE
SVSRILAIAATHELLSKQMEDGINLYMVIETVAYNVERCCNDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYDH
AFHPNESGEILLQIKEEKNIIHAEVSDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEFGTKTMFDFKYISIH
ATKK

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55475; Mature: 55344

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTIREMCLRYTDLAEYDIDELIHTAKSLSESSMYQDVDVFIDVYNKLTSEALVIHHMP
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PKTTKSLYKNNVVGETALRSNEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQR
CHHHHHHHHCCCCCHHHHCCCCCCEEHHHHCCCCCCCCHHHHHCCEEEHHHCCCCCCCCE
VIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSKLTDSITDQLDDAILIFDGKG
EEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
ILQQKNCAADQYYERLGYMENIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
CCCCCCCCHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVV
CCHHEEHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLRIQGRRSTSVEAQKVLNESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNVERC
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH
CNDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYDHAFHPNESGEILLQIKEEKN
HCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCC
IIHAEVSDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEFGTKTMFDFKYISI
EEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEE
HATKK
EECCC
>Mature Secondary Structure 
TKTIREMCLRYTDLAEYDIDELIHTAKSLSESSMYQDVDVFIDVYNKLTSEALVIHHMP
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCC
PKTTKSLYKNNVVGETALRSNEPGVLRTLETGMNSNDLLAKTQENVLIRQKVYPIRNKQR
CHHHHHHHHCCCCCHHHHCCCCCCEEHHHHCCCCCCCCHHHHHCCEEEHHHCCCCCCCCE
VIAVLILENDISAEIKAHFEIDNEETAYRDVSTTLSAMSKLTDSITDQLDDAILIFDGKG
EEEEEEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
ILQQKNCAADQYYERLGYMENIQGMHYDNLSLDQMMFDAIMYQIETGKQPIQLKKEVVIA
CCCCCCCCHHHHHHHHCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
GNYFIMKQIFVKEEDEQECRFILILHDITDIKVKEAEIVSKSVAIREIHHRVKNNLQSVV
CCHHEEHHHHHCCCCCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLRIQGRRSTSVEAQKVLNESVSRILAIAATHELLSKQMEDGINLYMVIETVAYNVERC
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHH
CNDCPKVAVRMDIDKRIYLDSDRTVALALVMNELLQNSYDHAFHPNESGEILLQIKEEKN
HCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCC
IIHAEVSDNGHGFNVRKVSEKSLGLSIVKSYIKDKLRGKVTIESNEFGTKTMFDFKYISI
EEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCEEEEEEEEEE
HATKK
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]